Cationic liposome conjugation to recombinant adenoviral vector reduces viral antigenicity

Japanese Journal of Cancer Research

Volumn 91, Issue 4, 2000, Pages 363-367

  Natsume, Atsushi ^a   Mizuno, Masaaki ^a   Ryuke, Yasushi ^a   Yoshida, Jun ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Adenoviral vector; Antigenicity; Liposome; Repeated administration

Indexed keywords

BETA GALACTOSIDASE; CATION; LIPOSOME; NEUTRALIZING ANTIBODY; VIRUS ANTIBODY; VIRUS VECTOR;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGENICITY; ARTICLE; CONTROLLED STUDY; DRUG CONJUGATION; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENE; VIRUS RECOMBINANT;

EID: 0034068970     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2000.tb00953.x     Document Type: Article

References (19)

1. Ali, M., Lemoine, N. R. and Ring, C. J. A. The use of DNA viruses as vectors for gene therapy. Gene Ther., 1, 367-384 (1994).
2. Akli, S., Caillaid, D., Vigne, E., Stradford-Perricaudet, L. D., Poenaru, L., Perricaudet, M., Kahn, A. and Perschanski, M. R. Transfer of a foreign gene into the brain using adenovirus vectors. Nat. Genet., 3, 224-228 (1993).
3. Bajocchi, G., Feldman, S. H., Crystal, R. G. and Mastrangeli, A. Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors. Nat. Genet., 3, 229-231 (1993).
4. Davidson, B. L., Allen, E. D., Kozarsky, K. F., Wilson, J. M. and Rosessler, B. J. A model system for in vivo gene transfer into the central nervous system using adenoviral vector. Nat. Genet., 3, 219-223 (1993).
5. Le Gal La Salle, G., Robert, J. J., Berrard, S., Ridoux, V. and Mallet, J. An adenovirus vector for gene transfer into neurons and glia in the brain. Science, 259, 988-990 (1993).
6. Viola, J. J., Ram, Z., Walbridge, S., Oshiro, E. M., Trapnell, B., Tao-Cheng, J.-H. and Oldfield, E. H. Adenovirally mediated gene transfer into experimental solid brain tumors and leptomeningeal cancer cells. J. Neurosurg., 82, 70-76 (1995).
7. Byrnes, A. P., MacLaren, R. F. and Charlton, H. M. Immunological instability of persistent adenovirus vectors in the brain: peripheral exposure to vector leads to renewed inflammation, reduced gene expression and demyelination. J. Neurosci., 16, 3045-3055 (1996).
8. Yang, Y., Greenough, K. and Wilson, J. M. Transient immune blockade prevents formulation of neutralizing anti-body to recombinant adenovirus and allows repeated gene transfer to mouse liver. Gene Ther., 3, 412-420 (1996).
9. Dewey, R. A., Morrissey, G., Cowsill, C. M., Stone, D., Bolognani, F., Dodd, N. J., Southgate, T. D., Klatzmann, D., Lassmann, H., Castro, M. G. and Lowenstein, P. R. Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trials. Nat. Med., 5, 1256-1263 (1999).
10. Kielian, T. and Hickey, W. F. Inflammatory thoughts about glioma gene therapy. Nat. Med., 5, 1237-1238 (1999).
11. Yoshida, J. and Mizuno, M. Simple preparation and characterization of cationic liposomes associated with a monoclonal antibody against glioma-associated antigen (immunoliposomes). J. Liposome Res., 5, 981-995 (1995).
12. Ryuke, Y., Mizuno, M., Natsume, A. and Yoshida, J. The transduction efficiency of adenoviral vectors increases by associating with cationic liposomes on human glioma cells. Neurol. Med. Chir. (Tokyo), in press.
13. Beer, S. J., Matthews, C. B., Stein, C. S., Ross, B. D., Hilfinger, J. M. and Davidson, B. L. Poly (lactic-glycolic) acid copolymer encapsulation of recombinant adenovirus reduces immunogenicity in vivo. Gene Ther., 5, 740-746 (1998).
14. Raja-Walia, R., Webber, J., Naftilan, J., Chapman, G. D. and Naftilan, A. J. Enhancement of liposome-mediated gene transfer into vascular tissue by replication deficient adenovirus. Gene Ther., 2, 521-530 (1995).
15. Kreuzer, J., Denger, S., Reifers, F., Beisel, C., Haack, K., Gebert, J. and Kubler, W. Adenovirus-assisted lipofection: efficient in vitro gene transfer of luciferase and cytosine deaminase to human smooth muscle cells. Atherosclerosis, 124, 49-60 (1996).
16. Fasbender, A., Zabner, J., Chillon, M., Moninger, T. O., Puga, A. P., Davidson, B. L. and Welsh, M. J. Complexes of adenovirus with polycationic polymers and cationic lipids increase the efficiency of gene transfer in vitro and in vivo. J. Biol. Chem., 272, 6479-6489 (1997).
17. Gao, G.-P., Yang, Y. and Wilson, J. M. Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy. J. Virol. 70, 8934-8943 (1996).
18. Benihoud, K., Saggio, I., Opolon, P., Salone, B., Amiot, F., Connault, E., Chianale, C. Dautry, F., Yeh, P. and Perricaudet, M. Efficient, repeated adenovirus-mediated gene transfer in mice lacking both tumor necrosis factor alpha and lymphotoxin α. J. Virol., 72, 9514-9525 (1998).
19. Fortin, A., Shahum, E., Krzystyniak, K. and Therien, H. M. Differential activation of cell-mediated immune functions by encapsulated and surface-linked liposomal antigens. Cell Immunol., 169, 208-217 (1996).