Targeting adenovirus

Gene Therapy

Volumn 7, Issue 2, 2000, Pages 110-114

  Wickham, T J ^a  

^a GENVEC INC   (United States)

Author keywords

Adenovirus; Gene therapy; Receptor; Targeting; Vector

Indexed keywords

CELL RECEPTOR; COAT PROTEIN; VIRUS VECTOR;

ADENOVIRUS; CANCER; CARDIOVASCULAR DISEASE; CELL TYPE; COMPLEX FORMATION; GENE LOCATION; GENE TARGETING; GENE THERAPY; GENE TRANSFER; GENETIC ENGINEERING; IMMUNE RESPONSE; IMMUNOGENICITY; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SAFETY; SHORT SURVEY; TOXICITY; VIRUS ADSORPTION; VIRUS MORPHOLOGY;

EID: 0033954001     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301115     Document Type: Short Survey

References (18)

1. Bergelson JM et al. Isolation of a common receptor for coxsackie B viruses and adenoviruses 2 and 5. Science 1997; 275: 1320-1323.
2. Tomko RP, Xu R, Philipson L. HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses. Proc Natl Acad Sci USA 1997; 94: 3352-3356.
3. Wickham TJ, Mathias P, Cheresh DA, Nemerow GR. Integrins avb3 and avb5 promote adenovirus internalization but not virus attachment. Cell 1993; 73: 309-319.
4. Nemerow GR, Stewart PL. Role of αv integrins in adenovirus cell entry and gene delivery. Microbiol Molec Biol Rev 1999; 63: 725-734.
5. Hong SS et al. Adenovirus type 5 fiber knob binds to MHC class I a2 domain at the surface of human epithelial and B lymphoblastoid cells. EMBO J 1997; 16: 2294-2306.
6. Davison E, Kirby I, Elliott T, Santis G. The human HLA-A*0201 allele, expressed in hamster cells, is not a high-affinity receptor for adenovirus type 5 fiber. J Virol 1999; 73: 4513-4517.
7. Stewart PL, Fuller SD, Burnett RM. Difference imaging of adenovirus: bridging the resolution gap between X-ray crystallography and electron microscopy. EMBO J 1993; 12: 2589-2599.
8. Stewart PL et al. Cryo-EM visualization of an exposed RGD epitope on adenovirus that escapes antibody neutralization. EMBO J 1997; 16: 1189-1198.
9. Athappilly FK et al. The refined crystal structure of hexon, the major coat protein of adenovirus type 2, at 2.9 A resolution. J Mol Biol 1994; 242: 430-455.
10. Xia D, Henry LJ, Gerard RD, Deisenhofer J. Crystal Structure of the receptor-binding domain of adenovirus type 5 fiber protein at 1.7 A resolution. Structure 1994; 2: 1259-1270.
11. Roelvink PR, Lee GM, Kovesdi I, Wickham TJ. Identification of a conserved receptor binding site on the fiber proteins of CAR recognizing adenoviridae. Science 1999; 286: 1568-1571.
12. Douglas JT et al. Targeted gene delivery by tropism-modified adenoviral vectors. Nat Biotech 1996; 14: 1574-1578.
13. Wickham TJ, Roelvink PW, Brough DE, Kovesdi I. Adenovirus targeted to heparin-containing receptors increases its gene delivery efficiency to multiple cell types. Nat Biotech 1996; 14: 1570-1573.
14. Wickham TJ et al. Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins. J Virol 1997; 71: 8221-8229.
15. Shinoura N et al. Highly augmented cytopathic effect of a fiber-mutant E1B-defective adenovirus for gene therapy of gliomas. Cancer Res 1999; 59: 3411-3416.
16. Rajotte D et al. Molecular heterogeneity of the vascular endothelium revealed by in vivo phage display. J Clin Invest 1998; 102: 430-437.
17. Einfeld DA et al. Construction of a pseudoreceptor that mediates transduction by adenoviruses expressing a ligand in fiber or penton base. J Virol 1999; 73: 9130-9136.
18. Douglas JT et al. A system for the propagation of adenoviral vectors with genetically modified receptor specificities. Nat Biotechnol 1999; 17: 470-475.