Ablating adenovirus type 5 fiber-CAR binding and HI loop insertion of the SIGYPLP peptide generate an endothelial cell-selective adenovirus

Molecular Therapy

Volumn 4, Issue 6, 2001, Pages 534-542

  Nicklin, Stuart A ^a   Von Seggern, Dan J ^b   Work, Lorraine M ^a   Pek, Don C K ^a   Dominiczak, Anna F ^a   Nemerow, Glen R ^b   Baker, Andrew H ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Adenovirus; CAR ablation; Endothelial cells; HI loop; Peptides; Phage display; Targeting

Indexed keywords

BINDING PROTEIN; BISPECIFIC ANTIBODY; LIGAND; VIRUS PROTEIN; VIRUS RECEPTOR; VIRUS VECTOR;

ADENOVIRUS 5; ARTICLE; BINDING AFFINITY; CELL SELECTION; CELL SPECIFICITY; CONTROLLED STUDY; COXSACKIE VIRUS; ENDOTHELIUM CELL; GENE INSERTION; GENE MUTATION; GENE TARGETING; GENETIC ENGINEERING; HUMAN; HUMAN CELL; POINT MUTATION; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; SAFETY; VIRION;

ADENOVIRIDAE; COXSACKIEVIRUS; HUMAN ADENOVIRUS TYPE 5; INSERTION SEQUENCES; MAMMALIA;

EID: 0035661202     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2001.0489     Document Type: Article

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