-
1
-
-
0033591428
-
Phylogenetic perspectives in innate immunity
-
Hoffmann, J. A., Kafatos, F. C., Janeway, C. A., Ezekowitz, R. A. (1999) Phylogenetic perspectives in innate immunity. Science 284, 1313-1318.
-
(1999)
Science
, vol.284
, pp. 1313-1318
-
-
Hoffmann, J.A.1
Kafatos, F.C.2
Janeway, C.A.3
Ezekowitz, R.A.4
-
2
-
-
0037184995
-
Pattern recognition receptors: Doubling up for the innate immune response
-
Gordon, S. (2002) Pattern recognition receptors: doubling up for the innate immune response. Cell 111, 927-930.
-
(2002)
Cell
, vol.111
, pp. 927-930
-
-
Gordon, S.1
-
3
-
-
0030595339
-
The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults
-
Lemaitre, B., Nicolas, E., Michaut, L., Reichhart, J., Hoffmann, J. (1996) The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86, 973-983.
-
(1996)
Cell
, vol.86
, pp. 973-983
-
-
Lemaitre, B.1
Nicolas, E.2
Michaut, L.3
Reichhart, J.4
Hoffmann, J.5
-
4
-
-
0037083557
-
The Toll pathway is required for resistance to gram-positive bacterial infections in Drosophila
-
Rutschmann, S., Kilinc, A., Ferrandon, D. (2002) The Toll pathway is required for resistance to gram- positive bacterial infections in Drosophila. J. Immunol. 168, 1542-1546.
-
(2002)
J. Immunol.
, vol.168
, pp. 1542-1546
-
-
Rutschmann, S.1
Kilinc, A.2
Ferrandon, D.3
-
5
-
-
0034708614
-
The Drosophila genome sequence: Implications for biology and medicine
-
Komberg, T. B., Krasnow, M. A. (2000) The Drosophila genome sequence: implications for biology and medicine. Science 287, 2218-2220.
-
(2000)
Science
, vol.287
, pp. 2218-2220
-
-
Komberg, T.B.1
Krasnow, M.A.2
-
6
-
-
0036167107
-
Drosophila innate immunity: An evolutionary perspective
-
Hoffmann, J. A., Reichhart, J. M. (2002) Drosophila innate immunity: an evolutionary perspective. Nat. Immunol. 3, 121-126.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 121-126
-
-
Hoffmann, J.A.1
Reichhart, J.M.2
-
7
-
-
0037290892
-
Drosophila immunity: Paths and patterns
-
Hultmark, D. (2003) Drosophila immunity: paths and patterns. Curr. Opin. Immunol. 15, 12-19.
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 12-19
-
-
Hultmark, D.1
-
8
-
-
0036160153
-
How Drosophila combats microbial infection: A model to study innate immunity and host-pathogen interactions
-
Tzou, P., De Gregorio, E., Lemaitre, B. (2002) How Drosophila combats microbial infection: a model to study innate immunity and host-pathogen interactions. Curr. Opin. Microbiol. 5, 102-110.
-
(2002)
Curr. Opin. Microbiol.
, vol.5
, pp. 102-110
-
-
Tzou, P.1
De Gregorio, E.2
Lemaitre, B.3
-
9
-
-
0034084438
-
TLR4 mutations are associated with endotoxin hyporesponsiveness in humans
-
Arbour, N. C., Lorenz, E., Schutte, B. C., Zabner, J., Kline, J. N., Jones, M., Frees, K., Watt, J. L., Schwartz, D. A. (2000) TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat. Genet. 25, 187-191.
-
(2000)
Nat. Genet.
, vol.25
, pp. 187-191
-
-
Arbour, N.C.1
Lorenz, E.2
Schutte, B.C.3
Zabner, J.4
Kline, J.N.5
Jones, M.6
Frees, K.7
Watt, J.L.8
Schwartz, D.A.9
-
10
-
-
0037378655
-
Cutting edge: A toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling
-
Bochud, P. Y., Hawn, T. R., Aderem, A. (2003) Cutting edge: a toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling. J. Immunol. 170, 3451-3454.
-
(2003)
J. Immunol.
, vol.170
, pp. 3451-3454
-
-
Bochud, P.Y.1
Hawn, T.R.2
Aderem, A.3
-
11
-
-
0037130195
-
Toll-like receptor 4 polymorphisms and atherogenesis
-
Kiechl, S., Lorenz, E., Reindl, M., Wiedermann, C. J., Oberhollenzer, F., Bonora, E., Willeit, J., Schwartz, D. A. (2002) Toll-like receptor 4 polymorphisms and atherogenesis. N. Engl. J. Med. 347, 185-192.
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 185-192
-
-
Kiechl, S.1
Lorenz, E.2
Reindl, M.3
Wiedermann, C.J.4
Oberhollenzer, F.5
Bonora, E.6
Willeit, J.7
Schwartz, D.A.8
-
12
-
-
0033794461
-
A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection
-
Lorenz, E., Mira, J. P., Cornish, K. L., Arbour, N. C., Schwartz, D. A. (2000) A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection. Infect. Immun. 68, 6398-6401.
-
(2000)
Infect. Immun.
, vol.68
, pp. 6398-6401
-
-
Lorenz, E.1
Mira, J.P.2
Cornish, K.L.3
Arbour, N.C.4
Schwartz, D.A.5
-
13
-
-
0037465251
-
The interleukin-1 receptor/Toll-like receptor superfamily: Signal transduction during inflammation and host defense
-
Dunne, A., O'Neill, L. A. (2003) The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense. Sci STKE 2003, re3.
-
(2003)
Sci STKE
, vol.2003
-
-
Dunne, A.1
O'Neill, L.A.2
-
14
-
-
0035399769
-
Toll receptors in innate immunity
-
Imler, J., Hoffmann, J. A. (2001) Toll receptors in innate immunity. Trends Cell Biol. 11, 304-311.
-
(2001)
Trends Cell Biol.
, vol.11
, pp. 304-311
-
-
Imler, J.1
Hoffmann, J.A.2
-
15
-
-
0036467389
-
IL-1 and IL-18 receptors, and their extended family
-
Sims, J. E. (2002) IL-1 and IL-18 receptors, and their extended family. Curr. Opin. Immunol. 14, 117-122.
-
(2002)
Curr. Opin. Immunol.
, vol.14
, pp. 117-122
-
-
Sims, J.E.1
-
16
-
-
0036793439
-
TIR-X and TIR-NBS proteins: Two new families related to disease resistance TIR-NBS-LRR proteins encoded in Arabidopsis and other plant genomes
-
Meyers, B. C., Morgante, M., Michelmore, R. W. (2002) TIR-X and TIR-NBS proteins: two new families related to disease resistance TIR-NBS-LRR proteins encoded in Arabidopsis and other plant genomes. Plant J. 32, 77-92.
-
(2002)
Plant J.
, vol.32
, pp. 77-92
-
-
Meyers, B.C.1
Morgante, M.2
Michelmore, R.W.3
-
17
-
-
0029347064
-
The L6 gene for flax rust resistance is related to the Arabidopsis bacterial resistance gene RPS2 and the tobacco viral resistance gene N
-
Lawrence, G. J., Finnegan, E. J., Ayliffe, M. A., Ellis, J. G. (1995) The L6 gene for flax rust resistance is related to the Arabidopsis bacterial resistance gene RPS2 and the tobacco viral resistance gene N. Plant Cell 7, 1195-1206.
-
(1995)
Plant Cell
, vol.7
, pp. 1195-1206
-
-
Lawrence, G.J.1
Finnegan, E.J.2
Ayliffe, M.A.3
Ellis, J.G.4
-
18
-
-
0034098633
-
Independent evolution of Toll and related genes in insects and mammals
-
Luo, C., Zheng, L. (2000) Independent evolution of Toll and related genes in insects and mammals. Immunogenetics 51, 92-98.
-
(2000)
Immunogenetics
, vol.51
, pp. 92-98
-
-
Luo, C.1
Zheng, L.2
-
19
-
-
0036166242
-
The Drosophila Toll-9 activates a constitutive antimicrobial defense
-
Ooi, J. Y., Yagi, Y., Hu, X., Ip, Y. T. (2002) The Drosophila Toll-9 activates a constitutive antimicrobial defense. EMBO Rep. 3, 82-87.
-
(2002)
EMBO Rep.
, vol.3
, pp. 82-87
-
-
Ooi, J.Y.1
Yagi, Y.2
Hu, X.3
Ip, Y.T.4
-
20
-
-
0034641738
-
Toll-related receptors and the control of antimicrobial peptide expression in drosophila
-
Tauszig, S., Jouanguy, E., Hoffmann, J. A., Imler, J. L. (2000) Toll-related receptors and the control of antimicrobial peptide expression in drosophila. Proc. Natl. Acad. Sci. USA 97, 10520-10525.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10520-10525
-
-
Tauszig, S.1
Jouanguy, E.2
Hoffmann, J.A.3
Imler, J.L.4
-
21
-
-
0037020201
-
Immunity-related genes and gene families in Anopheles gambiae
-
Christophides, G. K., Zdobnov, E., Barillas-Mury, C., Birney, E., Blandin, S., Blass, C., Brey, P. T., Collins, F. H., Danielli, A., Dimopoulos, G., et al. (2002) Immunity-related genes and gene families in Anopheles gambiae. Science 298, 159-165.
-
(2002)
Science
, vol.298
, pp. 159-165
-
-
Christophides, G.K.1
Zdobnov, E.2
Barillas-Mury, C.3
Birney, E.4
Blandin, S.5
Blass, C.6
Brey, P.T.7
Collins, F.H.8
Danielli, A.9
Dimopoulos, G.10
-
22
-
-
0037319852
-
Characterization of three Toll-like genes from mosquito Aedes aegypti
-
Luna, C., Hoa, N. T., Zhang, J., Kanzok, S. M., Brown, S. E., Imler, J. L., Knudson, D. L., Zheng, L. (2003) Characterization of three Toll-like genes from mosquito Aedes aegypti. Insect Mol. Biol. 12, 67-74.
-
(2003)
Insect Mol. Biol.
, vol.12
, pp. 67-74
-
-
Luna, C.1
Hoa, N.T.2
Zhang, J.3
Kanzok, S.M.4
Brown, S.E.5
Imler, J.L.6
Knudson, D.L.7
Zheng, L.8
-
23
-
-
0036453721
-
Evolution of the TIR, tolls and TLRs: Functional inferences from computational biology
-
Beutler, B., Rehli, M. (2002) Evolution of the TIR, tolls and TLRs: functional inferences from computational biology. Curr. Top. Microbiol. Immunol. 270, 1-21.
-
(2002)
Curr. Top. Microbiol. Immunol.
, vol.270
, pp. 1-21
-
-
Beutler, B.1
Rehli, M.2
-
24
-
-
0036712463
-
Characterization of four Toll related genes during development and immune responses in Anopheles gambiae
-
Luna, C., Wang, X., Huang, Y., Zhang, J., Zheng, L. (2002) Characterization of four Toll related genes during development and immune responses in Anopheles gambiae. Insect Biochem. Mol. Biol. 32, 1171-1179.
-
(2002)
Insect Biochem. Mol. Biol.
, vol.32
, pp. 1171-1179
-
-
Luna, C.1
Wang, X.2
Huang, Y.3
Zhang, J.4
Zheng, L.5
-
25
-
-
0036023960
-
Critical evaluation of the role of the Toll-like receptor 18-Wheeler in the host defense of Drosophila
-
Ligoxygakis, P., Bulet, P., Reichhart, J. M. (2002) Critical evaluation of the role of the Toll-like receptor 18-Wheeler in the host defense of Drosophila. EMBO Rep. 3, 666-673.
-
(2002)
EMBO Rep.
, vol.3
, pp. 666-673
-
-
Ligoxygakis, P.1
Bulet, P.2
Reichhart, J.M.3
-
26
-
-
0036141954
-
Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections
-
Tauszig-Delamasure, S., Bilak, H., Capovilla, M., Hoffmann, J. A., Imler, J. L. (2002) Drosophila MyD88 is required for the response to fungal and Gram- positive bacterial infections. Nat. Immunol. 3, 91-97.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 91-97
-
-
Tauszig-Delamasure, S.1
Bilak, H.2
Capovilla, M.3
Hoffmann, J.A.4
Imler, J.L.5
-
27
-
-
0037526795
-
Toll and Toll-like receptors in Drosophila
-
Bilak, H., Tauszig-Delamasure, S., Imler, J. L. (2003) Toll and Toll-like receptors in Drosophila. Biochem. Soc. Trans. 31, 648-651.
-
(2003)
Biochem. Soc. Trans.
, vol.31
, pp. 648-651
-
-
Bilak, H.1
Tauszig-Delamasure, S.2
Imler, J.L.3
-
28
-
-
0034777255
-
Tehao functions in the Toll pathway in Drosophila melanogaster: Possible roles in development and innate immunity
-
Luo, C., Shen, B., Manley, J. L., Zheng, L. (2001) Tehao functions in the Toll pathway in Drosophila melanogaster: possible roles in development and innate immunity. Insect Mol. Biol. 10, 457-464.
-
(2001)
Insect Mol. Biol.
, vol.10
, pp. 457-464
-
-
Luo, C.1
Shen, B.2
Manley, J.L.3
Zheng, L.4
-
29
-
-
0036952124
-
Tissue and stage-specific expression of the Tolls in Drosophila embryos
-
Kambris, Z., Hoffmann, J. A., Imler, J. L., Capovilla, M. (2002) Tissue and stage-specific expression of the Tolls in Drosophila embryos. Gene Expr. Patterns 2, 311-317.
-
(2002)
Gene Expr. Patterns
, vol.2
, pp. 311-317
-
-
Kambris, Z.1
Hoffmann, J.A.2
Imler, J.L.3
Capovilla, M.4
-
30
-
-
0029730738
-
A conserved signaling pathway: The Drosophila toll-dorsal pathway
-
Belvin, M. P., Anderson, K. V. (1996) A conserved signaling pathway: the Drosophila toll-dorsal pathway. Annu. Rev. Cell Dev. Biol. 12, 393-416.
-
(1996)
Annu. Rev. Cell Dev. Biol.
, vol.12
, pp. 393-416
-
-
Belvin, M.P.1
Anderson, K.V.2
-
31
-
-
0028038271
-
Expression of a novel Toll-like gene spans the parasegment boundary and contributes to hedgehog function in the adult eye of Drosophila
-
Chiang, C., Beachy, P. A. (1994) Expression of a novel Toll-like gene spans the parasegment boundary and contributes to hedgehog function in the adult eye of Drosophila. Mech. Dev. 47, 225-239.
-
(1994)
Mech. Dev.
, vol.47
, pp. 225-239
-
-
Chiang, C.1
Beachy, P.A.2
-
32
-
-
0028326047
-
The Drosophila 18 wheeler is required for morphogenesis and has striking similarities to Toll
-
Eldon, E., Kooyer, S., D'Evelyn, D., Duman, M., Lawinger, P., Botas, J., Bellen, H. (1994) The Drosophila 18 wheeler is required for morphogenesis and has striking similarities to Toll. Development 120, 885-899.
-
(1994)
Development
, vol.120
, pp. 885-899
-
-
Eldon, E.1
Kooyer, S.2
D'Evelyn, D.3
Duman, M.4
Lawinger, P.5
Botas, J.6
Bellen, H.7
-
33
-
-
0037383779
-
Induction of neuron-specific glycosylation by Tollo/Toll-8, a Drosophila Toll-like receptor expressed in non-neural cells
-
Seppo, A., Matani, P., Sharrow, M., Tiemeyer, M. (2003) Induction of neuron-specific glycosylation by Tollo/Toll-8, a Drosophila Toll-like receptor expressed in non-neural cells. Development 130, 1439-1448.
-
(2003)
Development
, vol.130
, pp. 1439-1448
-
-
Seppo, A.1
Matani, P.2
Sharrow, M.3
Tiemeyer, M.4
-
34
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak, A., He, X., Smirnova, I., Liu, M., Huffel, C., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., et al. (1998) Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282, 2085-2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.4
Huffel, C.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
-
35
-
-
0345561540
-
Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)
-
see comments
-
Qureshi, S. T., Lariviere, L., Leveque, G., Clermont, S., Moore, K. J., Gros, P., Malo, D. (1999) Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4). J. Exp. Med. 189, 615-625 (see comments) (published erratum appears in J Exp Med 1999 May 3;189(9):following 1518).
-
(1999)
J. Exp. Med.
, vol.189
, pp. 615-625
-
-
Qureshi, S.T.1
Lariviere, L.2
Leveque, G.3
Clermont, S.4
Moore, K.J.5
Gros, P.6
Malo, D.7
-
36
-
-
0345561540
-
-
(published erratum appears, May 3; following 1518)
-
Qureshi, S. T., Lariviere, L., Leveque, G., Clermont, S., Moore, K. J., Gros, P., Malo, D. (1999) Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4). J. Exp. Med. 189, 615-625 (see comments) (published erratum appears in J Exp Med 1999 May 3;189(9):following 1518).
-
(1999)
J Exp Med
, vol.189
, Issue.9
-
-
-
37
-
-
0033213590
-
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
-
Takeuchi, O., Hoshino, K., Kawai, T., Sanjo, H., Takada, H., Ogawa, T., Takeda, K., Akira, S. (1999) Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11, 443-451.
-
(1999)
Immunity
, vol.11
, pp. 443-451
-
-
Takeuchi, O.1
Hoshino, K.2
Kawai, T.3
Sanjo, H.4
Takada, H.5
Ogawa, T.6
Takeda, K.7
Akira, S.8
-
38
-
-
0036344106
-
Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice
-
Alexopoulou, L., Thomas, V., Schnare, M., Lobet, Y., Anguita, J., Schoen, R. T., Medzhitov, R., Fikrig, E., Flavell, R. A. (2002) Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice. Nat. Med. 8, 878-884.
-
(2002)
Nat. Med.
, vol.8
, pp. 878-884
-
-
Alexopoulou, L.1
Thomas, V.2
Schnare, M.3
Lobet, Y.4
Anguita, J.5
Schoen, R.T.6
Medzhitov, R.7
Fikrig, E.8
Flavell, R.A.9
-
39
-
-
0034922923
-
Discrimination of bacterial lipoproteins by Toll-like receptor 6
-
Takeuchi, O., Kawai, T., Muhlradt, P. F., Morr, M., Radolf, J. D., Zychlinsky, A., Takeda, K., Akira, S. (2001) Discrimination of bacterial lipoproteins by Toll-like receptor 6. Int. Immunol. 13, 933-940.
-
(2001)
Int. Immunol.
, vol.13
, pp. 933-940
-
-
Takeuchi, O.1
Kawai, T.2
Muhlradt, P.F.3
Morr, M.4
Radolf, J.D.5
Zychlinsky, A.6
Takeda, K.7
Akira, S.8
-
40
-
-
0036644042
-
Cutting edge: Role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins
-
Takeuchi, O., Sato, S., Horiuchi, T., Hoshino, K., Takeda, K., Dong, Z., Modlin, R. L., Akira, S. (2002) Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins. J. Immunol. 169, 10-14.
-
(2002)
J. Immunol.
, vol.169
, pp. 10-14
-
-
Takeuchi, O.1
Sato, S.2
Horiuchi, T.3
Hoshino, K.4
Takeda, K.5
Dong, Z.6
Modlin, R.L.7
Akira, S.8
-
41
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-kappaB by Toll- like receptor 3
-
Alexopoulou, L., Holt, A. C., Medzhitov, R., Flavell, R. A. (2001) Recognition of double-stranded RNA and activation of NF-kappaB by Toll- like receptor 3. Nature 413, 732-738.
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
42
-
-
0035953543
-
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
-
Hayashi, F., Smith, K. D., Ozinsky, A., Hawn, T. R., Yi, E. C., Goodlett, D. R., Eng, J. K., Akira, S., Underhill, D. M., Aderem, A. (2001) The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 410, 1099-1103.
-
(2001)
Nature
, vol.410
, pp. 1099-1103
-
-
Hayashi, F.1
Smith, K.D.2
Ozinsky, A.3
Hawn, T.R.4
Yi, E.C.5
Goodlett, D.R.6
Eng, J.K.7
Akira, S.8
Underhill, D.M.9
Aderem, A.10
-
43
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
In Process Citation
-
Hemmi, H., Takeuchi, O., Kawai, T., Kaisho, T., Sato, S., Sanjo, H., Matsumoto, M., Hoshino, K., Wagner, H., Takeda, K., et al. (2000) A Toll-like receptor recognizes bacterial DNA. Nature 408, 740-745 (In Process Citation).
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
Sanjo, H.6
Matsumoto, M.7
Hoshino, K.8
Wagner, H.9
Takeda, K.10
-
44
-
-
0036008014
-
Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
-
Hemmi, H., Kaisho, T., Takeuchi, O., Sato, S., Sanjo, H., Hoshino, K., Horiuchi, T., Tomizawa, H., Takeda, K., Akira, S. (2002) Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat. Immunol. 3, 196-200.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 196-200
-
-
Hemmi, H.1
Kaisho, T.2
Takeuchi, O.3
Sato, S.4
Sanjo, H.5
Hoshino, K.6
Horiuchi, T.7
Tomizawa, H.8
Takeda, K.9
Akira, S.10
-
45
-
-
0037036469
-
TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells
-
Abreu, M. T., Arnold, E. T., Thomas, L. S., Gonsky, R., Zhou, Y., Hu, B., Arditi, M. (2002) TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells. J. Biol. Chem. 277, 20431-20437.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 20431-20437
-
-
Abreu, M.T.1
Arnold, E.T.2
Thomas, L.S.3
Gonsky, R.4
Zhou, Y.5
Hu, B.6
Arditi, M.7
-
46
-
-
0034703072
-
CD14-dependent lipopolysaccharide-induced beta -defensin-2 expression in human tracheobronchial epithelium
-
Becker, M. N., Diamond, G., Verghese, M. W., Randell, S. H. (2000) CD14-dependent lipopolysaccharide-induced beta -defensin-2 expression in human tracheobronchial epithelium. J. Biol. Chem. 275, 29731-29736.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 29731-29736
-
-
Becker, M.N.1
Diamond, G.2
Verghese, M.W.3
Randell, S.H.4
-
47
-
-
0035881675
-
Cutting edge: Bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression
-
Gewirtz, A. T., Navas, T. A., Lyons, S., Godowski, P. J., Madara, J. L. (2001) Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression. J. Immunol. 167, 1882-1885.
-
(2001)
J. Immunol.
, vol.167
, pp. 1882-1885
-
-
Gewirtz, A.T.1
Navas, T.A.2
Lyons, S.3
Godowski, P.J.4
Madara, J.L.5
-
48
-
-
0037018107
-
Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells
-
Hornef, M. W., Frisan, T., Vandewalle, A., Normark, S., Richter-Dahlfors, A. (2002) Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells. J. Exp. Med. 195, 559-570.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 559-570
-
-
Hornef, M.W.1
Frisan, T.2
Vandewalle, A.3
Normark, S.4
Richter-Dahlfors, A.5
-
49
-
-
0037446528
-
Strategic compartmentalization of toll-like receptor 4 in the mouse gut
-
Ortega-Cava, C. F., Ishihara, S., Rumi, M. A., Kawashima, K., Ishimura, N., Kazumori, H., Udagawa, J., Kadowaki, Y., Kinoshita, Y. (2003) Strategic compartmentalization of toll-like receptor 4 in the mouse gut. J. Immunol. 170, 3977-3985.
-
(2003)
J. Immunol.
, vol.170
, pp. 3977-3985
-
-
Ortega-Cava, C.F.1
Ishihara, S.2
Rumi, M.A.3
Kawashima, K.4
Ishimura, N.5
Kazumori, H.6
Udagawa, J.7
Kadowaki, Y.8
Kinoshita, Y.9
-
50
-
-
0034610291
-
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
-
Ozinsky, A., Underhill, D. M., Fontenot, J. D., Hajjar, A. M., Smith, K. D., Wilson, C. B., Schroeder, L., Aderem, A. (2000) The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc. Natl. Acad. Sci. USA 97, 13766-13771.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13766-13771
-
-
Ozinsky, A.1
Underhill, D.M.2
Fontenot, J.D.3
Hajjar, A.M.4
Smith, K.D.5
Wilson, C.B.6
Schroeder, L.7
Aderem, A.8
-
51
-
-
0036301797
-
Essential role of MD-2 in LPS responsiveness and TLR4 distribution
-
Nagai, Y., Akashi, S., Nagafuku, M., Ogata, M., Iwakura, Y., Akira, S., Kitamura, T., Kosugi, A., Kimoto, M., Miyake, K. (2002) Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nat. Immunol. 3, 667-672.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 667-672
-
-
Nagai, Y.1
Akashi, S.2
Nagafuku, M.3
Ogata, M.4
Iwakura, Y.5
Akira, S.6
Kitamura, T.7
Kosugi, A.8
Kimoto, M.9
Miyake, K.10
-
52
-
-
0032997542
-
Recognition of gram-negative bacteria and endotoxin by the innate immune system
-
Ulevitch, R. J., Tobias, P. S. (1999) Recognition of gram-negative bacteria and endotoxin by the innate immune system. Curr. Opin. Immunol. 11, 19-22.
-
(1999)
Curr. Opin. Immunol.
, vol.11
, pp. 19-22
-
-
Ulevitch, R.J.1
Tobias, P.S.2
-
53
-
-
0036829687
-
Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2
-
Biragyn, A., Ruffini, P. A., Leifer, C. A., Klyushnenkova, E., Shakhov, A., Chertov, O., Shirakawa, A. K., Farber, J. M., Segal, D. M., Oppenheim, J. J., et al. (2002) Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2. Science 298, 1025-1029.
-
(2002)
Science
, vol.298
, pp. 1025-1029
-
-
Biragyn, A.1
Ruffini, P.A.2
Leifer, C.A.3
Klyushnenkova, E.4
Shakhov, A.5
Chertov, O.6
Shirakawa, A.K.7
Farber, J.M.8
Segal, D.M.9
Oppenheim, J.J.10
-
54
-
-
0037097672
-
Cutting edge: The immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4
-
Guillot, L., Balloy, V., McCormack, F. X., Golenbock, D. T., Chignard, M., Si-Tahar, M. (2002) Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4. J. Immunol. 168, 5989-5992.
-
(2002)
J. Immunol.
, vol.168
, pp. 5989-5992
-
-
Guillot, L.1
Balloy, V.2
McCormack, F.X.3
Golenbock, D.T.4
Chignard, M.5
Si-Tahar, M.6
-
55
-
-
0037094084
-
Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4
-
Johnson, G. B., Brunn, G. J., Kodaira, Y., Platt, J. L. (2002) Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4. J. Immunol. 168, 5233-5239.
-
(2002)
J. Immunol.
, vol.168
, pp. 5233-5239
-
-
Johnson, G.B.1
Brunn, G.J.2
Kodaira, Y.3
Platt, J.L.4
-
56
-
-
0035971217
-
The extra domain A of fibronectin activates Toll-like receptor 4
-
Okamura, Y., Watari, M., Jerud, E. S., Young, D. W., Ishizaka, S. T., Rose, J., Chow, J. C., Strauss, J. F., III (2001) The extra domain A of fibronectin activates Toll-like receptor 4. J. Biol. Chem. 276, 10229-10233.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 10229-10233
-
-
Okamura, Y.1
Watari, M.2
Jerud, E.S.3
Young, D.W.4
Ishizaka, S.T.5
Rose, J.6
Chow, J.C.7
Strauss III, J.F.8
-
57
-
-
0035451118
-
Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4
-
Smiley, S. T., King, J. A., Hancock, W. W. (2001) Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4. J. Immunol. 167, 2887-2894.
-
(2001)
J. Immunol.
, vol.167
, pp. 2887-2894
-
-
Smiley, S.T.1
King, J.A.2
Hancock, W.W.3
-
58
-
-
0037033364
-
Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4
-
Termeer, C., Benedix, F., Sleeman, J., Fieber, C., Voith, U., Ahrens, T., Miyake, K., Freudenberg, M., Galanos, C., Simon, J. C. (2002) Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4. J. Exp. Med. 195, 99-111.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 99-111
-
-
Termeer, C.1
Benedix, F.2
Sleeman, J.3
Fieber, C.4
Voith, U.5
Ahrens, T.6
Miyake, K.7
Freudenberg, M.8
Galanos, C.9
Simon, J.C.10
-
59
-
-
0036452764
-
Heat shock proteins as ligands of toll-like receptors
-
Vabulas, R. M., Wagner, H., Schild, H. (2002) Heat shock proteins as ligands of toll-like receptors. Curr. Top. Microbiol. Immunol. 270, 169-184.
-
(2002)
Curr. Top. Microbiol. Immunol.
, vol.270
, pp. 169-184
-
-
Vabulas, R.M.1
Wagner, H.2
Schild, H.3
-
60
-
-
0037414787
-
Endotoxin contamination in recombinant human heat shock protein 70 (Hsp70) preparation is responsible for the induction of tumor necrosis factor alpha release by murine macrophages
-
Gao, B., Tsan, M. F. (2003) Endotoxin contamination in recombinant human heat shock protein 70 (Hsp70) preparation is responsible for the induction of tumor necrosis factor alpha release by murine macrophages. J. Biol. Chem. 278, 174-179.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 174-179
-
-
Gao, B.1
Tsan, M.F.2
-
61
-
-
0035877718
-
Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. Transfer from CD14 to TLR4 and MD-2
-
da Silva Correia, J., Soldau, K., Christen, U., Tobias, P. S., Ulevitch, R. J. (2001) Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2. J. Biol. Chem. 276, 21129-21135.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21129-21135
-
-
Da Silva Correia, J.1
Soldau, K.2
Christen, U.3
Tobias, P.S.4
Ulevitch, R.J.5
-
62
-
-
0034002247
-
Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide
-
Lien, E., Means, T. K., Heine, H., Yoshimura, A., Kusumoto, S., Fukase, K., Fenton, M. J., Oikawa, M., Qureshi, N., Monks, B., et al. (2000) Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide. J. Clin. Invest. 105, 497-504.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 497-504
-
-
Lien, E.1
Means, T.K.2
Heine, H.3
Yoshimura, A.4
Kusumoto, S.5
Fukase, K.6
Fenton, M.J.7
Oikawa, M.8
Qureshi, N.9
Monks, B.10
-
63
-
-
0034007076
-
Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation
-
Poltorak, A., Ricciardi-Castagnoli, P., Citterio, S., Beutler, B. (2000) Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation. Proc. Natl. Acad. Sci. USA 97, 2163-2167.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2163-2167
-
-
Poltorak, A.1
Ricciardi-Castagnoli, P.2
Citterio, S.3
Beutler, B.4
-
64
-
-
0032033030
-
Proteolytic processing of the Drosophila Spatzle protein by easter generates a dimeric NGF-like molecule with ventralising activity
-
DeLotto, Y., DeLotto, R. (1998) Proteolytic processing of the Drosophila Spatzle protein by easter generates a dimeric NGF-like molecule with ventralising activity. Mech. Dev. 72, 141-148.
-
(1998)
Mech. Dev.
, vol.72
, pp. 141-148
-
-
DeLotto, Y.1
DeLotto, R.2
-
65
-
-
0041989575
-
Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling
-
Weber, A. N. R., Tauszig-Delamasure, S., Hoffman, J. A., Leliévre, E., Gascan, H., Ray, K. P., Morse, M. A., Imler, J. L., Gay, N. J. (2003) Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling. Nat. Immunol. 4, 723-724.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 723-724
-
-
Weber, A.N.R.1
Tauszig-Delamasure, S.2
Hoffman, J.A.3
Leliévre, E.4
Gascan, H.5
Ray, K.P.6
Morse, M.A.7
Imler, J.L.8
Gay, N.J.9
-
66
-
-
0035479747
-
A family of proteins related to Spatzle, the toll receptor ligand, are encoded in the Drosophila genome
-
Parker, J. S., Mizuguchi, K., Gay, N. J. (2001) A family of proteins related to Spatzle, the toll receptor ligand, are encoded in the Drosophila genome. Proteins 45, 71-80.
-
(2001)
Proteins
, vol.45
, pp. 71-80
-
-
Parker, J.S.1
Mizuguchi, K.2
Gay, N.J.3
-
67
-
-
0035856990
-
Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein
-
Michel, T., Reichhart, J. M., Hoffmann, J. A., Royet, J. (2001) Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein. Nature 414, 756-759.
-
(2001)
Nature
, vol.414
, pp. 756-759
-
-
Michel, T.1
Reichhart, J.M.2
Hoffmann, J.A.3
Royet, J.4
-
68
-
-
0037025213
-
Activation of Drosophila Toll during fungal infection by a blood serine protease
-
Ligoxygakis, P., Pelte, N., Hoffmann, J. A., Reichhart, J. M. (2002) Activation of Drosophila Toll during fungal infection by a blood serine protease. Science 297, 114-116.
-
(2002)
Science
, vol.297
, pp. 114-116
-
-
Ligoxygakis, P.1
Pelte, N.2
Hoffmann, J.A.3
Reichhart, J.M.4
-
69
-
-
0037218616
-
By IL-1 signaling, monocyte-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide
-
Liu, L., Roberts, A. A., Ganz, T. (2003) By IL-1 signaling, monocyte-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide. J. Immunol. 170, 575-580.
-
(2003)
J. Immunol.
, vol.170
, pp. 575-580
-
-
Liu, L.1
Roberts, A.A.2
Ganz, T.3
-
70
-
-
0000215491
-
Production of beta-defensins by human airway epithelia
-
Singh, P. K., Jia, H. P., Wiles, K., Hesselberth, J., Liu, L., Conway, B. A., Greenberg, E. P., Valore, E. V., Welsh, M. J., Ganz, T., et al. (1998) Production of beta-defensins by human airway epithelia. Proc. Natl. Acad. Sci. USA 95, 14961-14966.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 14961-14966
-
-
Singh, P.K.1
Jia, H.P.2
Wiles, K.3
Hesselberth, J.4
Liu, L.5
Conway, B.A.6
Greenberg, E.P.7
Valore, E.V.8
Welsh, M.J.9
Ganz, T.10
-
71
-
-
0035524488
-
Toll-like receptors and innate immunity
-
Medzhitov, R. (2001) Toll-like receptors and innate immunity. Nat. Rev. Immunol. 1, 135-145.
-
(2001)
Nat. Rev. Immunol.
, vol.1
, pp. 135-145
-
-
Medzhitov, R.1
-
72
-
-
0036709969
-
A universal role for MyD88 in TLR/IL-1R-mediated signaling
-
Janssens, S., Beyaert, R. (2002) A universal role for MyD88 in TLR/IL-1R-mediated signaling. Trends Biochem. Sci. 27, 474-482.
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 474-482
-
-
Janssens, S.1
Beyaert, R.2
-
73
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai, T., Adachi, O., Ogawa, T., Takeda, K., Akira, S. (1999) Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11, 115-122.
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
74
-
-
0033968625
-
Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades
-
In Process Citation
-
Takeuchi, O., Takeda, K., Hoshino, K., Adachi, O., Ogawa, T., Akira, S. (2000) Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades. Int. Immunol. 12, 113-117 (In Process Citation).
-
(2000)
Int. Immunol.
, vol.12
, pp. 113-117
-
-
Takeuchi, O.1
Takeda, K.2
Hoshino, K.3
Adachi, O.4
Ogawa, T.5
Akira, S.6
-
75
-
-
0035339861
-
Endotoxin-induced maturation of MyD88-deficient dendritic cells
-
Kaisho, T., Takeuchi, O., Kawai, T., Hoshino, K., Akira, S. (2001) Endotoxin-induced maturation of MyD88-deficient dendritic cells. J. Immunol. 166, 5688-5694.
-
(2001)
J. Immunol.
, vol.166
, pp. 5688-5694
-
-
Kaisho, T.1
Takeuchi, O.2
Kawai, T.3
Hoshino, K.4
Akira, S.5
-
76
-
-
18644376284
-
IRF3 Mediates a TLR3/TLR4-Specific Antiviral Gene Program
-
Doyle, S., Vaidya, S., O'Connell, R., Dadgostar, H., Dempsey, P., Wu, T., Rao, G., Sun, R., Haberland, M., Modlin, R., et al. (2002) IRF3 Mediates a TLR3/TLR4-Specific Antiviral Gene Program. Immunity 17, 251-263.
-
(2002)
Immunity
, vol.17
, pp. 251-263
-
-
Doyle, S.1
Vaidya, S.2
O'Connell, R.3
Dadgostar, H.4
Dempsey, P.5
Wu, T.6
Rao, G.7
Sun, R.8
Haberland, M.9
Modlin, R.10
-
77
-
-
0035889228
-
Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes
-
Kawai, T., Takeuchi, O., Fujita, T., Inoue, J., Muhlradt, P. F., Sato, S., Hoshino, K., Akira, S. (2001) Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes. J. Immunol. 167, 5887-5894.
-
(2001)
J. Immunol.
, vol.167
, pp. 5887-5894
-
-
Kawai, T.1
Takeuchi, O.2
Fujita, T.3
Inoue, J.4
Muhlradt, P.F.5
Sato, S.6
Hoshino, K.7
Akira, S.8
-
78
-
-
0037153130
-
The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
-
Horng, T., Barton, G. M., Flavell, R. A., Medzhitov, R. (2002) The adaptor molecule TIRAP provides signalling specificity for Toll- like receptors. Nature 420, 329-333.
-
(2002)
Nature
, vol.420
, pp. 329-333
-
-
Horng, T.1
Barton, G.M.2
Flavell, R.A.3
Medzhitov, R.4
-
79
-
-
0037153191
-
Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4
-
Yamamoto, M., Sato, S., Hemmi, H., Sanjo, H., Uematsu, S., Kaisho, T., Hoshino, K., Takeuchi, O., Kobayashi, M., Fujita, T., et al. (2002) Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4. Nature 420, 324-329.
-
(2002)
Nature
, vol.420
, pp. 324-329
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Sanjo, H.4
Uematsu, S.5
Kaisho, T.6
Hoshino, K.7
Takeuchi, O.8
Kobayashi, M.9
Fujita, T.10
-
80
-
-
0037307766
-
Krapfen/dMyd88 is required for the establishment of dorsoventral pattern in the Drosophila embryo
-
Charatsi, I., Luschnig, S., Bartoszewski, S., Nusslein-Volhard, C., Moussian, B. (2003) Krapfen/dMyd88 is required for the establishment of dorsoventral pattern in the Drosophila embryo. Mech. Dev. 120, 219-226.
-
(2003)
Mech. Dev.
, vol.120
, pp. 219-226
-
-
Charatsi, I.1
Luschnig, S.2
Bartoszewski, S.3
Nusslein-Volhard, C.4
Moussian, B.5
-
81
-
-
0035940499
-
Drosophila MyD88 is an adapter in the Toll signaling pathway
-
Horng, T., Medzhitov, R. (2001) Drosophila MyD88 is an adapter in the Toll signaling pathway. Proc. Natl. Acad. Sci. USA 98, 12654-12658.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12654-12658
-
-
Horng, T.1
Medzhitov, R.2
-
82
-
-
0036791016
-
A heterotrimeric death domain complex in Toll signaling
-
Sun, H., Bristow, B. N., Qu, G., Wasserman, S. A. (2002) A heterotrimeric death domain complex in Toll signaling. Proc. Natl. Acad. Sci. USA 99, 12871-12876.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 12871-12876
-
-
Sun, H.1
Bristow, B.N.2
Qu, G.3
Wasserman, S.A.4
-
83
-
-
0037320451
-
TICAM-1, an adapter molecule that participates in Toll-like receptor 3-mediated interferon-β induction
-
Oshiumi, H., Matsumoto, M., Funami, K., Akazawa, T., Seya, T. (2003) TICAM-1, an adapter molecule that participates in Toll-like receptor 3-mediated interferon-β induction. Nat. Immunol. 4, 161-167.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 161-167
-
-
Oshiumi, H.1
Matsumoto, M.2
Funami, K.3
Akazawa, T.4
Seya, T.5
-
84
-
-
0037114185
-
Cutting Edge: A Novel Toll/IL-1 Receptor Domain-Containing Adapter That Preferentially Activates the IFN-beta Promoter in the Toll-Like Receptor Signaling
-
Yamamoto, M., Sato, S., Mori, K., Hoshino, K., Takeuchi, O., Takeda, K., Akira, S. (2002) Cutting Edge: A Novel Toll/IL-1 Receptor Domain-Containing Adapter That Preferentially Activates the IFN-beta Promoter in the Toll-Like Receptor Signaling. J. Immunol. 169, 6668-6672.
-
(2002)
J. Immunol.
, vol.169
, pp. 6668-6672
-
-
Yamamoto, M.1
Sato, S.2
Mori, K.3
Hoshino, K.4
Takeuchi, O.5
Takeda, K.6
Akira, S.7
-
85
-
-
0037454946
-
Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4
-
Burns, K., Janssens, S., Brissoni, B., Olivos, N., Beyaert, R., Tschopp, J. (2003) Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. J. Exp. Med. 197, 263-268.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 263-268
-
-
Burns, K.1
Janssens, S.2
Brissoni, B.3
Olivos, N.4
Beyaert, R.5
Tschopp, J.6
-
86
-
-
0037219193
-
DmMyD88 controls dorsoventral patterning of the Drosophila embryo
-
Kambris, Z., Bilak, H., D'Alessandro, R., Belvin, M., Imler, J. L., Capovilla, M. (2003) DmMyD88 controls dorsoventral patterning of the Drosophila embryo. EMBO Rep. 4, 64-69.
-
(2003)
EMBO Rep.
, vol.4
, pp. 64-69
-
-
Kambris, Z.1
Bilak, H.2
D'Alessandro, R.3
Belvin, M.4
Imler, J.L.5
Capovilla, M.6
-
87
-
-
0037292275
-
Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members
-
Janssens, S., Beyaert, R. (2003) Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members. Mol. Cell 11, 293-302.
-
(2003)
Mol. Cell
, vol.11
, pp. 293-302
-
-
Janssens, S.1
Beyaert, R.2
-
88
-
-
0037129212
-
Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4
-
Suzuki, N., Suzuki, S., Duncan, G. S., Millar, D. G., Wada, T., Mirtsos, C., Takada, H., Wakeham, A., Itie, A., Li, S., et al. (2002) Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4. Nature 416, 750-756.
-
(2002)
Nature
, vol.416
, pp. 750-756
-
-
Suzuki, N.1
Suzuki, S.2
Duncan, G.S.3
Millar, D.G.4
Wada, T.5
Mirtsos, C.6
Takada, H.7
Wakeham, A.8
Itie, A.9
Li, S.10
-
89
-
-
0034655280
-
IL-1 receptor-associated kinase modulates host responsiveness to endotoxin
-
Swantek, J. L., Tsen, M. F., Cobb, M. H. Thomas, J. A. (2000) IL-1 receptor-associated kinase modulates host responsiveness to endotoxin. J. Immunol. 164, 4301-4306.
-
(2000)
J. Immunol.
, vol.164
, pp. 4301-4306
-
-
Swantek, J.L.1
Tsen, M.F.2
Cobb, M.H.3
Thomas, J.A.4
-
90
-
-
0033565779
-
Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase
-
Thomas, J. A., Allen, J. L., Tsen, M., Dubnicoff, T., Danao, J., Liao, X. C., Cao, Z., Wasserman, S. A. (1999) Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase. J. Immunol. 163, 978-984.
-
(1999)
J. Immunol.
, vol.163
, pp. 978-984
-
-
Thomas, J.A.1
Allen, J.L.2
Tsen, M.3
Dubnicoff, T.4
Danao, J.5
Liao, X.C.6
Cao, Z.7
Wasserman, S.A.8
-
91
-
-
0037178785
-
IRAK-M is a negative regulator of Toll-like receptor signaling
-
Kobayashi, K., Hernandez, L. D., Galan, J. E., Janeway, C. A., Jr., Medzhitov, R., Flavell, R. A. (2002) IRAK-M is a negative regulator of Toll-like receptor signaling. Cell 110, 191-202.
-
(2002)
Cell
, vol.110
, pp. 191-202
-
-
Kobayashi, K.1
Hernandez, L.D.2
Galan, J.E.3
Janeway Jr., C.A.4
Medzhitov, R.5
Flavell, R.A.6
-
92
-
-
0034644474
-
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
-
Deng, L., Wang, C., Spencer, E., Yang, L., Braun, A., You, J., Slaughter, C., Pickart, C., Chen, Z. J. (2000) Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell 103, 351-361.
-
(2000)
Cell
, vol.103
, pp. 351-361
-
-
Deng, L.1
Wang, C.2
Spencer, E.3
Yang, L.4
Braun, A.5
You, J.6
Slaughter, C.7
Pickart, C.8
Chen, Z.J.9
-
93
-
-
0035913278
-
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
-
Wang, C., Deng, L., Hong, M., Akkaraju, G. R., Inoue, J., Chen, Z. J. (2001) TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature 412, 346-351.
-
(2001)
Nature
, vol.412
, pp. 346-351
-
-
Wang, C.1
Deng, L.2
Hong, M.3
Akkaraju, G.R.4
Inoue, J.5
Chen, Z.J.6
-
94
-
-
0035883151
-
NF-kappaB signaling pathways in mammalian and insect innate immunity
-
Silverman, N., Maniatis, T. (2001) NF-kappaB signaling pathways in mammalian and insect innate immunity. Genes Dev. 15, 2321-2342.
-
(2001)
Genes Dev.
, vol.15
, pp. 2321-2342
-
-
Silverman, N.1
Maniatis, T.2
-
95
-
-
0035187882
-
The antibacterial arm of the drosophila innate immune response requires an IkappaB kinase
-
Lu, Y., Wu, L. P., Anderson, K. V. (2001) The antibacterial arm of the drosophila innate immune response requires an IkappaB kinase. Genes Dev. 15, 104-110.
-
(2001)
Genes Dev.
, vol.15
, pp. 104-110
-
-
Lu, Y.1
Wu, L.P.2
Anderson, K.V.3
-
96
-
-
0034303573
-
Role of Drosophila IKKγ in a Toll-independent antibacterial immune response
-
Rutschmann, S., Jung, A., Zhou, R., Silverman, N., Hoffmann, J. A., Ferrandon, D. (2000) Role of Drosophila IKKγ in a Toll-independent antibacterial immune response. Nat. Immunol. 1, 342-347.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 342-347
-
-
Rutschmann, S.1
Jung, A.2
Zhou, R.3
Silverman, N.4
Hoffmann, J.A.5
Ferrandon, D.6
-
97
-
-
18744372992
-
The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway
-
Avila, A., Silverman, N., Diaz-Meco, M. T., Moscat, J. (2002) The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway. Mol. Cell. Biol. 22, 8787-8795.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 8787-8795
-
-
Avila, A.1
Silverman, N.2
Diaz-Meco, M.T.3
Moscat, J.4
-
98
-
-
0034577944
-
Toll-like receptor 2-mediated NF-κB activation requires a Rac1-dependent pathway
-
Arbibe, L., Mira, J., Teusch, N., Kline, L., Guha, M., Mackman, N., Godowski, P., Ulevitch, R., Knaus, U. (2000) Toll-like receptor 2-mediated NF-κB activation requires a Rac1-dependent pathway. Nat. Immunol. 1, 533-540.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 533-540
-
-
Arbibe, L.1
Mira, J.2
Teusch, N.3
Kline, L.4
Guha, M.5
Mackman, N.6
Godowski, P.7
Ulevitch, R.8
Knaus, U.9
-
99
-
-
0038701608
-
Double-stranded RNA Signaling by Toll-like Receptor 3 Requires Specific Tyrosine Residues in Its Cytoplasmic Domain
-
Sarkar, S. N., Smith, H. L., Rowe, T. M., Sen, G. C. (2003) Double-stranded RNA Signaling by Toll-like Receptor 3 Requires Specific Tyrosine Residues in Its Cytoplasmic Domain. J. Biol. Chem. 278, 4393-4396.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 4393-4396
-
-
Sarkar, S.N.1
Smith, H.L.2
Rowe, T.M.3
Sen, G.C.4
-
100
-
-
0034775153
-
Toll-like receptors control activation of adaptive immune responses
-
Schnare, M., Barton, G. M., Holt, A. C., Takeda, K., Akira, S., Medzhitov, R. (2001) Toll-like receptors control activation of adaptive immune responses. Nat. Immunol. 2, 947-950.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 947-950
-
-
Schnare, M.1
Barton, G.M.2
Holt, A.C.3
Takeda, K.4
Akira, S.5
Medzhitov, R.6
-
101
-
-
0037446651
-
Genetically resistant mice lacking MyD88-adapter protein display a high susceptibility to Leishmania major infection associated with a polarized Th2 response
-
Muraille, E., De Trez, C., Brait, M., De Baetselier, P., Leo, O., Carlier, Y. (2003) Genetically resistant mice lacking MyD88-adapter protein display a high susceptibility to Leishmania major infection associated with a polarized Th2 response. J. Immunol. 170, 4237-4241.
-
(2003)
J. Immunol.
, vol.170
, pp. 4237-4241
-
-
Muraille, E.1
De Trez, C.2
Brait, M.3
De Baetselier, P.4
Leo, O.5
Carlier, Y.6
-
102
-
-
0037121946
-
Lipopolysaccharide-enhanced, Toll-like Receptor 4-dependent T Helper Cell Type 2 Responses to Inhaled Antigen
-
Eisenbarth, S. C., Piggott, D. A., Huleatt, J. W., Visintin, I., Herrick, C. A., Bottomly, K. (2002) Lipopolysaccharide-enhanced, Toll-like Receptor 4-dependent T Helper Cell Type 2 Responses to Inhaled Antigen. J. Exp. Med. 196, 1645-1651.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 1645-1651
-
-
Eisenbarth, S.C.1
Piggott, D.A.2
Huleatt, J.W.3
Visintin, I.4
Herrick, C.A.5
Bottomly, K.6
-
103
-
-
0035554676
-
Regulatory T cells in the control of immune pathology
-
Maloy, K. J., Powrie, F. (2001) Regulatory T cells in the control of immune pathology. Nat. Immunol. 2, 816-822.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 816-822
-
-
Maloy, K.J.1
Powrie, F.2
-
104
-
-
0037436119
-
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
-
Pasare, C., Medzhitov, R. (2003) Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science 299, 1033-1036.
-
(2003)
Science
, vol.299
, pp. 1033-1036
-
-
Pasare, C.1
Medzhitov, R.2
-
105
-
-
0037061453
-
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
-
Leadbetter, E. A., Rifkin, I. R., Hohlbaum, A. M., Beaudette, B. C., Shlomchik, M. J., Marshak-Rothstein, A. (2002) Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors, Nature 416, 603-607.
-
(2002)
Nature
, vol.416
, pp. 603-607
-
-
Leadbetter, E.A.1
Rifkin, I.R.2
Hohlbaum, A.M.3
Beaudette, B.C.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
106
-
-
0033957469
-
SMART: A web-based tool for the study of genetically mobile domains
-
Schultz, J., Copley, R. R., Doerks, T., Ponting, C. P., Bork, P. (2000) SMART: a web-based tool for the study of genetically mobile domains. Nucleic Acids Res. 28, 231-234.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 231-234
-
-
Schultz, J.1
Copley, R.R.2
Doerks, T.3
Ponting, C.P.4
Bork, P.5
-
107
-
-
0031574072
-
The CLUSTAL_X windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools
-
Thompson, J. D., Gibson, T. J., Plewniak, F., Jeanmougin, F., Higgins, D. G. (1997) The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 25, 4876-4882.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 4876-4882
-
-
Thompson, J.D.1
Gibson, T.J.2
Plewniak, F.3
Jeanmougin, F.4
Higgins, D.G.5
|