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Volumn 3, Issue 1, 2002, Pages 91-97

Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; DROSOMYCIN; INTERLEUKIN 1 RECEPTOR; MYELOID DIFFERENTIATION FACTOR 88; UNCLASSIFIED DRUG;

EID: 0036141954     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni747     Document Type: Article
Times cited : (247)

References (50)
  • 2
  • 6
    • 0033578917 scopus 로고    scopus 로고
    • Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila
    • (1999) Science , vol.285 , pp. 1917-1919
    • Levashina, E.A.1
  • 8
    • 0033711445 scopus 로고    scopus 로고
    • The Rel protein DIF mediates the Toll-dependent antifungal response in Drosophila
    • (2000) Immunity , vol.12 , pp. 569-580
    • Rutschmann, S.1
  • 15
    • 0032133278 scopus 로고    scopus 로고
    • MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
    • (1998) Mol. Cell , vol.2 , pp. 253-258
    • Medzhitov, R.1
  • 18
    • 0033968625 scopus 로고    scopus 로고
    • Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades
    • (2000) Int. Immunol. , vol.12 , pp. 113-117
    • Takeuchi, O.1
  • 20
    • 0032415862 scopus 로고    scopus 로고
    • Phosphorylation modulates direct interactions between the Toll receptor, Pelle kinase and Tube
    • (1998) Development , vol.125 , pp. 4719-4728
    • Shen, B.1    Manley, J.L.2
  • 22
    • 0034597766 scopus 로고    scopus 로고
    • Structural basis for signal transduction by the Toll/interleukin-1 receptor domains
    • (2000) Nature , vol.408 , pp. 111-115
    • Xu, Y.1
  • 25
    • 18044400563 scopus 로고    scopus 로고
    • Drosophila immune deficiency (IMD) is a death domain protein that activates the antibacterial response and can promote apoptosis
    • (2001) Dev. Cell , vol.1 , pp. 503-514
    • Georgel, P.1
  • 28
    • 0034698739 scopus 로고    scopus 로고
    • Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF) 6
    • (2000) J. Exp. Med. , vol.192 , pp. 595-600
    • Hacker, H.1
  • 33
    • 0035423794 scopus 로고    scopus 로고
    • Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-κB-dependent innate immune responses
    • (2001) Genes Dev , vol.15 , pp. 1900-1912
    • Vidal, S.1
  • 35
    • 0033231556 scopus 로고    scopus 로고
    • Relish, a central factor in the control of humoral but not cellular immunity in Drosophila
    • (1999) Mol. Cell , vol.4 , pp. 1-20
    • Hedengren, M.1
  • 38
    • 0032509295 scopus 로고    scopus 로고
    • Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
    • (1998) Science , vol.282 , pp. 2085-2088
    • Poltorak, A.1
  • 39
    • 0345561540 scopus 로고    scopus 로고
    • Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)
    • [published erratum appears in J Exp Med 1999 May 3;189(9):following 1518]. Published erratum: J. Exp. Med. 189, 1518 (1999)
    • (1999) J. Exp. Med. , vol.189 , pp. 615-625
    • Qureshi, S.T.1
  • 40
    • 0028326047 scopus 로고
    • The Drosophila 18 wheeler is required for morphogenesis and has striking similarities to Toll
    • (1994) Development , vol.120 , pp. 885-899
    • Eldon, E.1
  • 41
    • 0024003902 scopus 로고
    • Zygotic expression and activity of the Drosophila Toll gene, a gene required maternally for embryonic dorsal-ventral pattern formation
    • (1988) Genetics , vol.119 , pp. 123-133
    • Gerttula, S.1    Jin, Y.S.2    Anderson, K.V.3
  • 42
    • 0024299087 scopus 로고
    • The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein
    • (1988) Cell , vol.52 , pp. 269-279
    • Hashimoto, C.1    Hudson, K.2    Anderson, K.3
  • 43
    • 0028038271 scopus 로고
    • Expression of a novel Toll-like gene spans the parasegment boundary and contributes to hedgehog function in the adult eye of Drosophila
    • (1994) Mech. Dev. , vol.47 , pp. 225-239
    • Chiang, C.1    Beachy, P.A.2
  • 49
    • 0001532967 scopus 로고    scopus 로고
    • Systematic gain-of-function genetics in Drosophila
    • (1998) Development , vol.125 , pp. 1049-1057
    • Rorth, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.