-
1
-
-
0028938482
-
Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles
-
Glover, D. M., Leibowitz, M. H., McLean, D. A. & Parry, H. Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles. Cell 81, 95-105 (1995).
-
(1995)
Cell
, vol.81
, pp. 95-105
-
-
Glover, D.M.1
Leibowitz, M.H.2
McLean, D.A.3
Parry, H.4
-
2
-
-
0023804548
-
Polo, a mitotic mutant of Drosophia displaying abnormal spindle poles
-
Sunkel, C. E. & Glover, D. M. Polo, a mitotic mutant of Drosophia displaying abnormal spindle poles. J. Cell Sci. 89, 25-38 (1988).
-
(1988)
J. Cell Sci.
, vol.89
, pp. 25-38
-
-
Sunkel, C.E.1
Glover, D.M.2
-
3
-
-
0027515186
-
Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast
-
Chan, C. S. & Botstein, D. Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast. Genetics 135, 677-691 (1993).
-
(1993)
Genetics
, vol.135
, pp. 677-691
-
-
Chan, C.S.1
Botstein, D.2
-
4
-
-
0035694554
-
The S. pombe aurora-related kinase Ark 1 associates with mitotic structures in a stage dependent manner and is required for chromosome segregation
-
Petersen, J., Paris, J., Willer, M., Philippe, M. & Hagan, I. M. The S. pombe aurora-related kinase Ark1 associates with mitotic structures in a stage dependent manner and is required for chromosome segregation. J. Cell Sci. 114, 4371-4384 (2001).
-
(2001)
J. Cell Sci.
, vol.114
, pp. 4371-4384
-
-
Petersen, J.1
Paris, J.2
Willer, M.3
Philippe, M.4
Hagan, I.M.5
-
5
-
-
0036223874
-
The Schizosaccharomyces pombe Aurora-related kinase Ark 1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis
-
Leverson, J. D., Huang, H. K., Forsburg, S. L. & Hunter, T. The Schizosaccharomyces pombe Aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis. Mol. Biol. Cell 13, 1132-1143 (2002).
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 1132-1143
-
-
Leverson, J.D.1
Huang, H.K.2
Forsburg, S.L.3
Hunter, T.4
-
6
-
-
0035252654
-
Chromosomal passengers and the (Aurora) ABCs of mitosis
-
Adams, R. R., Carmena, M. & Earnshaw, W. C. Chromosomal passengers and the (Aurora) ABCs of mitosis. Trends Cell Biol. 11, 49-54 (2001).
-
(2001)
Trends Cell Biol.
, vol.11
, pp. 49-54
-
-
Adams, R.R.1
Carmena, M.2
Earnshaw, W.C.3
-
7
-
-
0035235736
-
Mitotic kinases as regulators of cell division and its checkpoints
-
Nigg, E. A. Mitotic kinases as regulators of cell division and its checkpoints. Nature Rev. Mol. Cell. Biol. 2, 21-32 (2001).
-
(2001)
Nature Rev. Mol. Cell. Biol.
, vol.2
, pp. 21-32
-
-
Nigg, E.A.1
-
8
-
-
0032100685
-
A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
-
Bischoff, J. R. et al. A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers. EMBO J. 17, 3052-3065 (1998). Provides one of the first insights into the link between Aurora kinases and carcinogenesis.
-
(1998)
EMBO J.
, vol.17
, pp. 3052-3065
-
-
Bischoff, J.R.1
-
9
-
-
0033226802
-
Aurora/lpl1p-related kinases, a new oncogenic family of mitotic serine-threonine kinases
-
Giet, R. & Prigent, C. Aurora/lpl1p-related kinases, a new oncogenic family of mitotic serine-threonine kinases. J. Cell Sci. 112, 3591-3601 (1999).
-
(1999)
J. Cell Sci.
, vol.112
, pp. 3591-3601
-
-
Giet, R.1
Prigent, C.2
-
10
-
-
0037044846
-
Crystal structure of aurora-2, an oncogenic serine/threonine kinase
-
Cheetham, G. M. et al. Crystal structure of aurora-2, an oncogenic serine/threonine kinase. J. Biol. Chem. 277, 42419-42422 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42419-42422
-
-
Cheetham, G.M.1
-
11
-
-
1842848073
-
Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography
-
Nowakowski, J. et al. Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography. Structure 10, 1659-1667 (2002).
-
(2002)
Structure
, vol.10
, pp. 1659-1667
-
-
Nowakowski, J.1
-
12
-
-
0025975264
-
Chromosomal passengers: Towards an integrated view of mitosis
-
Earnshaw, W. C. & Bernat, R. L. Chromosomal passengers: towards an integrated view of mitosis. Chromosoma 100, 139-146 (1990).
-
(1990)
Chromosoma
, vol.100
, pp. 139-146
-
-
Earnshaw, W.C.1
Bernat, R.L.2
-
13
-
-
0032212717
-
Cloning of STK13, a third human protein kinase related to Drosophila aurora and budding yeast lpl1 that maps on chromosome 19q13.3-ter
-
Bernard, M., Sanseau, P., Henry, C., Couturier, A. & Prigent, C. Cloning of STK13, a third human protein kinase related to Drosophila aurora and budding yeast lpl1 that maps on chromosome 19q13.3-ter. Genomics 53, 406-409 (1998).
-
(1998)
Genomics
, vol.53
, pp. 406-409
-
-
Bernard, M.1
Sanseau, P.2
Henry, C.3
Couturier, A.4
Prigent, C.5
-
14
-
-
0031764068
-
Protein kinase profile of sperm and eggs: Cloning and characterization of two novel testis-specific protein kinases (AIE1, AIE2) related to yeast and fly chromosome segregation regulators
-
Tseng, T. C., Chen, S. H., Hsu, Y. P. & Tang, T. K. Protein kinase profile of sperm and eggs: cloning and characterization of two novel testis-specific protein kinases (AIE1, AIE2) related to yeast and fly chromosome segregation regulators. DNA Cell Biol. 17, 823-833 (1998).
-
(1998)
DNA Cell Biol.
, vol.17
, pp. 823-833
-
-
Tseng, T.C.1
Chen, S.H.2
Hsu, Y.P.3
Tang, T.K.4
-
15
-
-
0033548619
-
Cell cycle-dependent expression and centrosome localization of a third human aurora/lpl1-related protein kinase, AIK3
-
Kimura, M., Matsuda, Y., Yoshioka, T. & Okano, Y. Cell cycle-dependent expression and centrosome localization of a third human aurora/lpl1-related protein kinase, AIK3. J. Biol. Chem. 274, 7334-7340 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7334-7340
-
-
Kimura, M.1
Matsuda, Y.2
Yoshioka, T.3
Okano, Y.4
-
16
-
-
0033652421
-
Genomic organization, expression, and chromosome localization of a third aurora-related kinase gene, Aie1
-
Hu, H. M., Chuang, C. K., Lee, M. J., Tseng, T. C. & Tang, T. K. Genomic organization, expression, and chromosome localization of a third aurora-related kinase gene, Aie1. DNA Cell Biol. 19, 679-688 (2000).
-
(2000)
DNA Cell Biol.
, vol.19
, pp. 679-688
-
-
Hu, H.M.1
Chuang, C.K.2
Lee, M.J.3
Tseng, T.C.4
Tang, T.K.5
-
17
-
-
0031673072
-
A highly conserved centrosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos
-
Schumacher, J. M., Ashcroft, N., Donovan, P. J & Golden, A. A highly conserved centrosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos. Development 125, 4391-4402 (1998).
-
(1998)
Development
, vol.125
, pp. 4391-4402
-
-
Schumacher, J.M.1
Ashcroft, N.2
Donovan, P.J.3
Golden, A.4
-
18
-
-
0031938231
-
The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly
-
Roghi, C. et al. The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly. J. Cell Sci. 111, 557-572 (1998).
-
(1998)
J. Cell Sci.
, vol.111
, pp. 557-572
-
-
Roghi, C.1
-
19
-
-
0037005263
-
Molecular dynamics of aurora-A kinase in living mitotic cells simultaneously visualized with histone H3 and nuclear membrane protein importinα
-
Sugimoto, K. et al. Molecular dynamics of aurora-A kinase in living mitotic cells simultaneously visualized with histone H3 and nuclear membrane protein importinα. Cell Struct. Funct. 27, 457-467 (2002).
-
(2002)
Cell Struct. Funct.
, vol.27
, pp. 457-467
-
-
Sugimoto, K.1
-
20
-
-
0037117408
-
Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis
-
Berdnik, D. & Knoblich, J. A. Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis. Curr. Biol. 12, 640-647 (2002). This describes a role for Aurora A in asymmetric cell division and examines the dynamics of Aurora-A association with centrosomes.
-
(2002)
Curr. Biol.
, vol.12
, pp. 640-647
-
-
Berdnik, D.1
Knoblich, J.A.2
-
21
-
-
0034717818
-
TPX2, a novel Xenopus MAP involved in spindle pole organization
-
Wittmann, T. Wilm, M., Karsenti, E. & Vernos, I. TPX2, a novel Xenopus MAP involved in spindle pole organization. J. Cell Biol. 149, 1405-1418 (2000).
-
(2000)
J. Cell Biol.
, vol.149
, pp. 1405-1418
-
-
Wittmann, T.1
Wilm, M.2
Karsenti, E.3
Vernos, I.4
-
22
-
-
0036849137
-
Chromosome-induced microtubule assembly mediated by TPX 2 is required for spindle formation in HeLa cells
-
Gruss, O. J. et al. Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells. Nature Cell Biol. 4, 871-879 (2002).
-
(2002)
Nature Cell Biol.
, vol.4
, pp. 871-879
-
-
Gruss, O.J.1
-
23
-
-
0034949769
-
The non-catalytic domain of the Xenopus laevis aurora A kinase localises the protein to the centrosome
-
Giet, R. & Prigent, C. The non-catalytic domain of the Xenopus laevis aurora A kinase localises the protein to the centrosome. J. Cell Sci. 114, 2095-2104 (2001).
-
(2001)
J. Cell Sci.
, vol.114
, pp. 2095-2104
-
-
Giet, R.1
Prigent, C.2
-
24
-
-
0037017398
-
Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules
-
Giet, R. et al. Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules. J. Cell Biol. 156, 437-451 (2002). RNAi analysis confirms a role for Aurora A in centrosome maturation and separation.
-
(2002)
J. Cell Biol.
, vol.156
, pp. 437-451
-
-
Giet, R.1
-
25
-
-
0037135979
-
Human TPX2 is required for targeting Aurora-A kinase to the spindle
-
Kufer T. A. et al. Human TPX2 is required for targeting Aurora-A kinase to the spindle. J. Cell Biol. 158, 617-623 (2002).
-
(2002)
J. Cell Biol.
, vol.158
, pp. 617-623
-
-
Kufer, T.A.1
-
26
-
-
0035945342
-
Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans
-
Hannak, E., Kirkham, M., Hyman, A. A. & Oegema, K. Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans. J. Cell Biol. 155, 1109-1116 (2001).
-
(2001)
J. Cell Biol.
, vol.155
, pp. 1109-1116
-
-
Hannak, E.1
Kirkham, M.2
Hyman, A.A.3
Oegema, K.4
-
27
-
-
0033591432
-
The Xenopus laevis aurora-related protein kinase pEg2 associates with and phosphorylates the kinesin-related protein XIEg 5
-
Giet, R., Uzbekov, R., Cubizolles, F., Le Guellec, K. & Prigent, C. The Xenopus laevis aurora-related protein kinase pEg2 associates with and phosphorylates the kinesin-related protein XIEg5. J. Biol. Chem. 274, 15005-15013 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 15005-15013
-
-
Giet, R.1
Uzbekov, R.2
Cubizolles, F.3
Le Guellec, K.4
Prigent, C.5
-
28
-
-
0037341906
-
A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly
-
Tsai, M. Y. et al. A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly. Nature Cell Biol. 5, 242-248 (2003). This study shows that TPX2 activates Aurora-A kinase, and proposes that Aurora A might be an important downstream target of Ran-GTP in promoting mitotic spindle assembly.
-
(2003)
Nature Cell Biol.
, vol.5
, pp. 242-248
-
-
Tsai, M.Y.1
-
29
-
-
0033591373
-
Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran
-
Wilde, A. & Zheng, Y. Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran. Science 284, 1359-1362 (1999).
-
(1999)
Science
, vol.284
, pp. 1359-1362
-
-
Wilde, A.1
Zheng, Y.2
-
30
-
-
0033528994
-
The ran GTPase regulates mitotic spindle assembly
-
Kalab, P., Pu, R. T. & Dasso, M. The ran GTPase regulates mitotic spindle assembly. Curr. Biol. 9, 481-484 (1999).
-
(1999)
Curr. Biol.
, vol.9
, pp. 481-484
-
-
Kalab, P.1
Pu, R.T.2
Dasso, M.3
-
31
-
-
0033536178
-
Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation
-
Carazo-Salas, R. E. et al. Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation. Nature 400, 178-181 (1999).
-
(1999)
Nature
, vol.400
, pp. 178-181
-
-
Carazo-Salas, R.E.1
-
32
-
-
0037446847
-
A novel mechanism for activation of the protein kinase aurora a
-
Eyers, P. A., Erikson, E., Chen, L. G. & Maller, J. L. A novel mechanism for activation of the protein kinase aurora a. Curr. Biol. 13, 691-697 (2003). This study shows that TPX2 activates Aurora-A kinase in part by blocking the inactivation of the kinase by protein phosphatase 1.
-
(2003)
Curr. Biol.
, vol.13
, pp. 691-697
-
-
Eyers, P.A.1
Erikson, E.2
Chen, L.G.3
Maller, J.L.4
-
33
-
-
0343917044
-
The kinase Eg2 is a component of the Xenopus oocyte progesterone-activated signaling pathway
-
Andresson, T. & Ruderman, J. V. The kinase Eg2 is a component of the Xenopus oocyte progesterone-activated signaling pathway. EMBO J. 17, 5627-5637 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 5627-5637
-
-
Andresson, T.1
Ruderman, J.V.2
-
34
-
-
0034673706
-
Phosphorylation of CPE binding factor by Eg2 regulates translation of c-mos mRNA
-
Mendez, R. et al. Phosphorylation of CPE binding factor by Eg2 regulates translation of c-mos mRNA. Nature 404, 302-307 (2000). This describes the involvement of Aurora A in cell-cycle regulation by regulating poly(A) -dependent translation.
-
(2000)
Nature
, vol.404
, pp. 302-307
-
-
Mendez, R.1
-
35
-
-
0034015512
-
Progesterone regulates the accumulation and the activation of Eg 2 kinase in Xenopus oocytes
-
Frank-Vaillant, M. et al. Progesterone regulates the accumulation and the activation of Eg2 kinase in Xenopus oocytes. J. Cell. 113, 1127-1138 (2000).
-
(2000)
J. Cell.
, vol.113
, pp. 1127-1138
-
-
Frank-Vaillant, M.1
-
36
-
-
0037484346
-
Cdc2-Cyclin B triggers H3 kinase activation of Aurora-A in Xenopus oocytes
-
Maton, G. et al. Cdc2-Cyclin B triggers H3 kinase activation of Aurora-A in Xenopus oocytes. J. Biol. Chem. 278, 21439-21449 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 21439-21449
-
-
Maton, G.1
-
37
-
-
0032517860
-
AIR-2: An Aurora/lpl1-related protein kinase associated with chromosomes and midbody microtubules is required for polar body extrusion and cytokinesis in Caenorhabditis elegans embryos
-
Schumacher J. M., Golden, A. & Donovan, P. J. AIR-2: An Aurora/lpl1-related protein kinase associated with chromosomes and midbody microtubules is required for polar body extrusion and cytokinesis in Caenorhabditis elegans embryos. J. Cell Biol. 143, 1635-1646 (1998).
-
(1998)
J. Cell Biol.
, vol.143
, pp. 1635-1646
-
-
Schumacher, J.M.1
Golden, A.2
Donovan, P.J.3
-
38
-
-
0037462726
-
Involvement of Aurora A kinase during meiosis I-II transition in Xenopus oocytes
-
Castro, A., Mandart, E., Lorca, T. & Galas, S. Involvement of Aurora A kinase during meiosis I-II transition in Xenopus oocytes. J. Biol. Chem. 278, 2236-2241 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 2236-2241
-
-
Castro, A.1
Mandart, E.2
Lorca, T.3
Galas, S.4
-
39
-
-
0037180488
-
Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A
-
Littlepage, L. E. et al. Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A. Proc. Natl Acad. Sci. USA 99, 15440-15445 (2002). Systematic analysis of the residues that are relevant for regulation of Aurora-A kinase.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 15440-15445
-
-
Littlepage, L.E.1
-
40
-
-
0034609753
-
The mitotic senne/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation
-
Walter, A. O., Seghezzi, W., Korver, W., Sheung, J. & Lees, E. The mitotic senne/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation. Oncogene 19, 4906-4916 (2000).
-
(2000)
Oncogene
, vol.19
, pp. 4906-4916
-
-
Walter, A.O.1
Seghezzi, W.2
Korver, W.3
Sheung, J.4
Lees, E.5
-
41
-
-
0037131572
-
Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase lpl1p
-
Cheeseman, I. M. et al. Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase lpl1p. Cell 111, 163-172 (2002). This is the most thorough study yet of the protein targets of the Aurora kinase lpl1.
-
(2002)
Cell
, vol.111
, pp. 163-172
-
-
Cheeseman, I.M.1
-
42
-
-
0028304675
-
Type 1 protein phosphatase acts in opposition to lpL1 protein kinase in regulating yeast chromosome segregation
-
Francisco, L., Wang, W. & Chan, C. S. Type 1 protein phosphatase acts in opposition to lpL1 protein kinase in regulating yeast chromosome segregation. Mol. Cell. Biol. 14, 4731-4740 (1994).
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 4731-4740
-
-
Francisco, L.1
Wang, W.2
Chan, C.S.3
-
43
-
-
0035824660
-
Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle
-
Katayama, H., Zhou, H., Li, Q., Tatsuka, M. & Sen, S. Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle. J. Biol. Chem. 276, 46219-46224 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46219-46224
-
-
Katayama, H.1
Zhou, H.2
Li, Q.3
Tatsuka, M.4
Sen, S.5
-
44
-
-
0035854776
-
Chromatin-associated protein phosphatase 1 regulates Aurora-B and histone H3 phosphorylation
-
Murnion, M. E. et al. Chromatin-associated protein phosphatase 1 regulates Aurora-B and histone H3 phosphorylation. J. Biol. Chem. 276, 26656-26665 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 26656-26665
-
-
Murnion, M.E.1
-
45
-
-
0034213929
-
Degradation of human Aurora2 protein kinase by the anaphase-promoting complex-ubiquitin-proteasome pathway
-
Honda, K. et al. Degradation of human Aurora2 protein kinase by the anaphase-promoting complex-ubiquitin-proteasome pathway. Oncogene 19, 2812-2819 (2000).
-
(2000)
Oncogene
, vol.19
, pp. 2812-2819
-
-
Honda, K.1
-
46
-
-
0035984896
-
APC/Fizzy-Related targets Aurora-A kinase for proteolysis
-
Castro, A. et al. APC/Fizzy-Related targets Aurora-A kinase for proteolysis. EMBO Rep. 3, 457-462 (2002).
-
(2002)
EMBO Rep.
, vol.3
, pp. 457-462
-
-
Castro, A.1
-
47
-
-
12244301635
-
The D-Box-activating domain (DAD) is a new proteolysis signal that stimulates the silent D-Box sequence of Aurora-A
-
Castro, A. et al. The D-Box-activating domain (DAD) is a new proteolysis signal that stimulates the silent D-Box sequence of Aurora-A EMBO Rep. 3, 1209-1214 (2002).
-
(2002)
EMBO Rep.
, vol.3
, pp. 1209-1214
-
-
Castro, A.1
-
48
-
-
0036714512
-
Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A dunng mitotic exit
-
Littlepage, L. E. & Ruderman, J. V. Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A dunng mitotic exit. Genes Dev. 16, 2274-2285 (2002). References 46 and 48 do a good job of dissecting the complexities of Aurora-A regulation by the APC/C.
-
(2002)
Genes Dev.
, vol.16
, pp. 2274-2285
-
-
Littlepage, L.E.1
Ruderman, J.V.2
-
49
-
-
0037160088
-
Aurora-A kinase interacting protein (AIP), a novel negative regulator of human Aurora-A kinase
-
Kiat, L. S., Hui, K. M. & Gopalan, G. Aurora-A kinase interacting protein (AIP), a novel negative regulator of human Aurora-A kinase. J. Biol. Chem. 277, 45558-45565 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45558-45565
-
-
Kiat, L.S.1
Hui, K.M.2
Gopalan, G.3
-
50
-
-
0032472915
-
AIM-1: A mammalian midbody-associated protein required for cytokinesis
-
Terada, Y. et al. AIM-1: a mammalian midbody-associated protein required for cytokinesis. EMBO J. 17, 667-676 (1998). One of the first reports showing the requirement of Aurora B for cytokinesis.
-
(1998)
EMBO J.
, vol.17
, pp. 667-676
-
-
Terada, Y.1
-
51
-
-
0035858865
-
Essential roles of Drosophila inner centromere protein (INCENP) and Aurora-B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation
-
Adams, R. R., Maiato, H., Earnshaw, W. C. & Carmena, M. Essential roles of Drosophila inner centromere protein (INCENP) and Aurora-B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation. J. Cell Biol. 153, 865-880 (2001).
-
(2001)
J. Cell Biol.
, vol.153
, pp. 865-880
-
-
Adams, R.R.1
Maiato, H.2
Earnshaw, W.C.3
Carmena, M.4
-
52
-
-
0036223382
-
Probing the dynamics and functions of Aurora B kinase in living cells during mitosis and cytokinesis
-
Murata-Hori, M., Tatsuka, M. & Wang, Y. L. Probing the dynamics and functions of Aurora B kinase in living cells during mitosis and cytokinesis. Mol. Biol. Cell 13, 1099-1108 (2002). Examines the dynamic behaviour of Aurora-B kinase in vivo using green-fluorescent-protein-labelled protein.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 1099-1108
-
-
Murata-Hori, M.1
Tatsuka, M.2
Wang, Y.L.3
-
53
-
-
0014047913
-
Chromosome micromanipulation. I. The mechanics of chromosome attachment to the spindle
-
Nicklas, R. B. & Staehly, C. A. Chromosome micromanipulation. I. The mechanics of chromosome attachment to the spindle. Chromosoma 21, 1-16 (1967).
-
(1967)
Chromosoma
, vol.21
, pp. 1-16
-
-
Nicklas, R.B.1
Staehly, C.A.2
-
54
-
-
0029146196
-
Kinetochore chemistry is sensitive to tension and may link mitotic forces for a cell cycle checkpoint
-
Nicklas, R. B., Wards, S. C. & Gorbsky, G. J. Kinetochore chemistry is sensitive to tension and may link mitotic forces for a cell cycle checkpoint. J. Cell Biol. 130, 929-939 (1995).
-
(1995)
J. Cell Biol.
, vol.130
, pp. 929-939
-
-
Nicklas, R.B.1
Wards, S.C.2
Gorbsky, G.J.3
-
55
-
-
0036178929
-
Evidence that the lpl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections
-
Tanaka, T. U. et al. Evidence that the lpl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections. Cell 108, 317-329 (2002). This paper was the first to propose that lpl1 might be involved in the resolution of syntelic chromsome attachments.
-
(2002)
Cell
, vol.108
, pp. 317-329
-
-
Tanaka, T.U.1
-
56
-
-
0037018844
-
Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis
-
Kallio, M. J., McCleland, M. L., Stukenberg, P. T. & Gorbsky, G. J. Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis. Curr. Biol. 12, 900-905 (2002). Antibody injection is used to identify some of the many functions of Aurora B in mammalian cells.
-
(2002)
Curr. Biol.
, vol.12
, pp. 900-905
-
-
Kallio, M.J.1
McCleland, M.L.2
Stukenberg, P.T.3
Gorbsky, G.J.4
-
57
-
-
0013057087
-
Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2 and Cenp-E to kinetochores
-
Ditchfield, C. et al. Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2 and Cenp-E to kinetochores. J. Cell Biol. 161, 267-280 (2003). This description of a small-molecule inhibitor of Aurora B identifies a role for the kinase in the spindle-assembly checkpoint when the checkpoint is activated in the presence of microtubules by altering tension within the spindle.
-
(2003)
J. Cell Biol.
, vol.161
, pp. 267-280
-
-
Ditchfield, C.1
-
58
-
-
0038746733
-
The small molecule Hesperadin reveals a role for Aurora B in correcting kinatochore-microtubule attachment and in maintaining the spindle assembly checkpoint
-
Hauf, S. et al. The small molecule Hesperadin reveals a role for Aurora B in correcting kinatochore-microtubule attachment and in maintaining the spindle assembly checkpoint. J. Cell Biol. 161, 281-294 (2003). This description of a second small-molecule inhibitor of Aurora B provides the best evidence to date that the kinase is involved in the resolution of syntelic chromosomal attachments during prometaphase.
-
(2003)
J. Cell Biol.
, vol.161
, pp. 281-294
-
-
Hauf, S.1
-
59
-
-
0037018843
-
The kinase activity of Aurora B is required for kinetochore-microtubule interactions during mitosis
-
Murata-Hori, M. & Wang, Y. The kinase activity of Aurora B is required for kinetochore-microtubule interactions during mitosis. Curr. Biol. 12, 894-899 (2002).
-
(2002)
Curr. Biol.
, vol.12
, pp. 894-899
-
-
Murata-Hori, M.1
Wang, Y.2
-
60
-
-
0033106222
-
The conserved protein kinase lpl 1 regulates microtubule binding to kinetochores in budding yeast
-
Biggins, S. et al. The conserved protein kinase lpl1 regulates microtubule binding to kinetochores in budding yeast. Genes Dev. 13, 532-544 (1999).
-
(1999)
Genes Dev.
, vol.13
, pp. 532-544
-
-
Biggins, S.1
-
61
-
-
0035956434
-
Functional cooperation of Dam1, lpl1, and the inner centromere protein (INCENP)-related protein Sli 15 during chromosome segregation
-
Kang, J. et al. Functional cooperation of Dam1, lpl1, and the inner centromere protein (INCENP)-related protein Sli15 during chromosome segregation. J. Cell Biol. 155, 763-774 (2001).
-
(2001)
J. Cell Biol.
, vol.155
, pp. 763-774
-
-
Kang, J.1
-
62
-
-
0037415571
-
The budding yeast lpl1/Aurora protein kinase regulates mitotic spindle disassembly
-
Buvelot, S., Tatsutani, S. Y., Vermaak, D. & Biggins, S. The budding yeast lpl1/Aurora protein kinase regulates mitotic spindle disassembly. J. Cell Biol. 160, 329-339 (2003).
-
(2003)
J. Cell Biol.
, vol.160
, pp. 329-339
-
-
Buvelot, S.1
Tatsutani, S.Y.2
Vermaak, D.3
Biggins, S.4
-
63
-
-
0041467803
-
Kinetochore protein interactions and their regulation by the Aurora kinase lpl 1p
-
Shang, C. et al. Kinetochore protein interactions and their regulation by the Aurora kinase lpl1p. Mol. Biol. Cell 14, 3342-3355 (2003).
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 3342-3355
-
-
Shang, C.1
-
64
-
-
0041968963
-
Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis
-
Honda, R., Korner, R. & Nigg, E. A. Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis. Mol. Biol. Cell 14, 3325-3341 (2003). A thorough study of the regulation of Aurora-B kinase activity by INCENP and survivin.
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 3325-3341
-
-
Honda, R.1
Korner, R.2
Nigg, E.A.3
-
65
-
-
0035945340
-
CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis J
-
Zeitlin, S. G., Shelby, R. D. & Sullivan, K. F. CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis J. Cell. Biol. 155, 1147-1157 (2001).
-
(2001)
Cell. Biol.
, vol.155
, pp. 1147-1157
-
-
Zeitlin, S.G.1
Shelby, R.D.2
Sullivan, K.F.3
-
66
-
-
0017853206
-
Histone phosphorylation and chromatin structure during mitosis in Chinese hamster cells
-
Gudey, L. R., D'Anna, J. A., Barham, S. S., Deaven, L. L. & Tobey, R. A. Histone phosphorylation and chromatin structure during mitosis in Chinese hamster cells. Eur. J. Biochem. 84, 1-15 (1978).
-
(1978)
Eur. J. Biochem.
, vol.84
, pp. 1-15
-
-
Gudey, L.R.1
D'Anna, J.A.2
Barham, S.S.3
Deaven, L.L.4
Tobey, R.A.5
-
67
-
-
0034604354
-
Mitotic phosphorylation of histone H3 is governed by lpl1/aurora kinase and Glc7/PP 1 phosphatase in budding yeast and nematodes
-
Hsu, J. Y. et al. Mitotic phosphorylation of histone H3 is governed by lpl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes. Cell 102, 279-291 (2000).
-
(2000)
Cell
, vol.102
, pp. 279-291
-
-
Hsu, J.Y.1
-
68
-
-
0033637849
-
The survivin-like C. elegans BIR-1 protein acts with the Aurora-like kinase AIR-2 to affect chromosomes and the spindle midzone
-
Speliotes, E. K., Uren, A., Vaux, D. & Horvitz, H. R. The survivin-like C. elegans BIR-1 protein acts with the Aurora-like kinase AIR-2 to affect chromosomes and the spindle midzone. Mol. Cell 6, 211-223 (2000).
-
(2000)
Mol. Cell
, vol.6
, pp. 211-223
-
-
Speliotes, E.K.1
Uren, A.2
Vaux, D.3
Horvitz, H.R.4
-
69
-
-
0035911159
-
Drosophila Aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis
-
Giet, R. & Glover, D. M. Drosophila Aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis. J. Cell Biol. 152, 669-681 (2001).
-
(2001)
J. Cell Biol.
, vol.152
, pp. 669-681
-
-
Giet, R.1
Glover, D.M.2
-
70
-
-
0036142218
-
Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases
-
Crosio, C. et al. Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases Mol. Cell. Biol. 22, 874-885 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 874-885
-
-
Crosio, C.1
-
71
-
-
0036153807
-
ISWI remodeling complexes in Xenopus egg extracts: identification as major chromosomal components that are regulated by INCENP-aurora B
-
MacCallum, D. E., Losada, A., Kobayashi, R. & Hirano, T. ISWI remodeling complexes in Xenopus egg extracts: identification as major chromosomal components that are regulated by INCENP-aurora B. Mol. Biol. Cell 13, 25-39 (2002).
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 25-39
-
-
MacCallum, D.E.1
Losada, A.2
Kobayashi, R.3
Hirano, T.4
-
72
-
-
0033520367
-
Identification of a novel phosphorylation site on histone H 3 coupled with mitotic chromosome condensation
-
Goto, H et al. Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation. J. Biol. Chem. 274, 25543-25549 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 25543-25549
-
-
Goto, H.1
-
73
-
-
0036158780
-
Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation
-
Goto, H., Yasui, Y., Nigg, E. A. & Inagaki, M. Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation. Genes Cells 7, 11-17 (2002).
-
(2002)
Genes Cells
, vol.7
, pp. 11-17
-
-
Goto, H.1
Yasui, Y.2
Nigg, E.A.3
Inagaki, M.4
-
74
-
-
0034631960
-
The Xenopus laevis aurora/lp11p-related kinase pEg2 participates in the stability of the bipolar mitotic spindle
-
Giet, R. & Prigent, C. The Xenopus laevis aurora/lp11p-related kinase pEg2 participates in the stability of the bipolar mitotic spindle. Exp. Cell Res. 258, 145-151 (2000).
-
(2000)
Exp. Cell Res.
, vol.258
, pp. 145-151
-
-
Giet, R.1
Prigent, C.2
-
75
-
-
0037084037
-
The ABCs of SMC proteins: Two-armed ATPases for chromosome condensation, cohesion, and repair
-
Hirano, T. The ABCs of SMC proteins: two-armed ATPases for chromosome condensation, cohesion, and repair. Genes Dev. 16, 399-414 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 399-414
-
-
Hirano, T.1
-
76
-
-
0037380133
-
pombe Aurora kinase/survivin Is required for chromosome condensation and the spindle checkpoint attachment response
-
Petersen, J. & Hagan, I. M. S. pombe Aurora kinase/survivin Is required for chromosome condensation and the spindle checkpoint attachment response. Curr. Biol. 13, 590-597 (2003). This study uses yeast genetics to show a role for Aurora B and its associated protein survivin in the spindle-assembly checkpoint.
-
(2003)
Curr. Biol.
, vol.13
, pp. 590-597
-
-
Petersen, J.1
Hagan, I.M.S.2
-
77
-
-
0037076212
-
The Aurora B kinase AIR-2 regulates kinetochores during mitosis and is required for separation of homologous chromosomes during meiosis
-
Kaitna, S., Pasierbek, P., Jantsch, M., Loidl, J. & Glotzer, M. The Aurora B kinase AIR-2 regulates kinetochores during mitosis and is required for separation of homologous chromosomes during meiosis. Curr. Biol. 12, 798-812 (2002).
-
(2002)
Curr. Biol.
, vol.12
, pp. 798-812
-
-
Kaitna, S.1
Pasierbek, P.2
Jantsch, M.3
Loidl, J.4
Glotzer, M.5
-
78
-
-
0037087623
-
C. elegans condensin promotes mitotic chromosome architecture, centromere organization, and sister chromatid segregation during mitosis and meiosis
-
Hagstrom, K. A., Holmes, V. F., Cozzarelli, N. R. & Meyer, B. J. C. elegans condensin promotes mitotic chromosome architecture, centromere organization, and sister chromatid segregation during mitosis and meiosis. Genes Dev. 16, 729-742 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 729-742
-
-
Hagstrom, K.A.1
Holmes, V.F.2
Cozzarelli, N.R.3
Meyer, B.J.4
-
79
-
-
0037092044
-
The aurora kinase AIR-2 functions in the release of chromosome cohesion in Caenorhabditis elegans meiosis
-
Rogers, E., Bishop, J. D., Waddle, J. A., Schumacher, J. M. & Lin, R. The aurora kinase AIR-2 functions in the release of chromosome cohesion in Caenorhabditis elegans meiosis. J. Cell Biol. 157, 219-229 (2002). This provides important insights into the role of Aurora B in chromosome segregation in meiosis.
-
(2002)
J. Cell Biol.
, vol.157
, pp. 219-229
-
-
Rogers, E.1
Bishop, J.D.2
Waddle, J.A.3
Schumacher, J.M.4
Lin, R.5
-
80
-
-
18044404949
-
Scc1/Rad21/Mcd 1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells
-
Sonoda, E. et al. Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells. Dev. Cell 1, 759-770 (2001).
-
(2001)
Dev. Cell
, vol.1
, pp. 759-770
-
-
Sonoda, E.1
-
81
-
-
0032498786
-
A dominant mutant of inner centromere protein (INCENP), a chromosomal protein, disrupts prometaphase congression and cytokinesis
-
Mackay, A. M., Ainsztein, A., Eckley, D. M. & Earnshaw, W. C. A dominant mutant of inner centromere protein (INCENP), a chromosomal protein, disrupts prometaphase congression and cytokinesis. J. Cell Biol. 140, 991-1002 (1998).
-
(1998)
J. Cell Biol.
, vol.140
, pp. 991-1002
-
-
Mackay, A.M.1
Ainsztein, A.2
Eckley, D.M.3
Earnshaw, W.C.4
-
82
-
-
0034618724
-
INCENP binds the aurora-related kinase AIRK2. and is required to target it to chromosomes, the central spindle and cleavage furrow
-
Adams, R. R. et al. INCENP binds the aurora-related kinase AIRK2. and is required to target it to chromosomes, the central spindle and cleavage furrow. Curr. Biol 10, 1075-1078 (2000).
-
(2000)
Curr. Biol
, vol.10
, pp. 1075-1078
-
-
Adams, R.R.1
-
83
-
-
0034609747
-
Incenp and an Aurora-like kinase form a complex essential for chromosome segregation and efficient completion of cytokinesis
-
Kaitna, S., Mendoza, M., Jantsch-Plunger, V. & Glotzer, M. Incenp and an Aurora-like kinase form a complex essential for chromosome segregation and efficient completion of cytokinesis. Curr. Biol. 10, 1172-1181 (2000).
-
(2000)
Curr. Biol.
, vol.10
, pp. 1172-1181
-
-
Kaitna, S.1
Mendoza, M.2
Jantsch-Plunger, V.3
Glotzer, M.4
-
84
-
-
0034609763
-
The aurora-related kinase AIR-2 recruits ZEN-4/CeMKLP 1 to the mitotic spindle at metaphase and is required for cytokinesis
-
Severson, A. F., Hamill, D. R., Carter, J. C., Schumacher, J. & Bowerman, B. The aurora-related kinase AIR-2 recruits ZEN-4/CeMKLP1 to the mitotic spindle at metaphase and is required for cytokinesis. Curr. Biol. 10, 1162-1171 (2000).
-
(2000)
Curr. Biol.
, vol.10
, pp. 1162-1171
-
-
Severson, A.F.1
Hamill, D.R.2
Carter, J.C.3
Schumacher, J.4
Bowerman, B.5
-
85
-
-
0034536903
-
Myosin II regulatory light chain as a novel substrate for AIM-1, an aurora/lpl1p-related kinase from rat
-
Murata-Hori, M. et al. Myosin II regulatory light chain as a novel substrate for AIM-1, an aurora/lpl1p-related kinase from rat. J. Biochem (Tokyo) 128, 903-907 (2000).
-
(2000)
J. Biochem (Tokyo)
, vol.128
, pp. 903-907
-
-
Murata-Hori, M.1
-
86
-
-
0037424487
-
Aurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic process
-
Goto, H. et al. Aurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic process J. Biol. Chem. 278, 8526-8530 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8526-8530
-
-
Goto, H.1
-
87
-
-
0038371015
-
Functional significance of the specific sites phosphorylated in desmin at cleavage furrow: Aurora-B may phosphorylate and regulate Type III intermediate filaments during cytokinesis coordinatedly with Rho-kinase
-
Kawajin, A. et al. Functional significance of the specific sites phosphorylated in desmin at cleavage furrow: Aurora-B may phosphorylate and regulate Type III intermediate filaments during cytokinesis coordinatedly with Rho-kinase. Mol. Biol. Cell 14, 1489-1500 (2003).
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 1489-1500
-
-
Kawajin, A.1
-
88
-
-
18244430352
-
CYK-4: A Rho family GTPase activating protein (GAP) required for central spindle formation and cytokinesis
-
Jantsch-Plunger, V. et al. CYK-4: A Rho family GTPase activating protein (GAP) required for central spindle formation and cytokinesis J. Cell Biol. 149, 1391-1404 (2000).
-
(2000)
J. Cell Biol.
, vol.149
, pp. 1391-1404
-
-
Jantsch-Plunger, V.1
-
89
-
-
0037387766
-
Phosphorylation by Aurora B converts MgcRacGAP to a RhoGAP during cytokinesis
-
Minoshima, Y., et al. Phosphorylation by Aurora B converts MgcRacGAP to a RhoGAP during cytokinesis. Dev. Cell 4, 549-560 (2003). An elegant study that identifies a new substrate for Aurora B and shows how the kinase might participate in the regulation of cytokinesis.
-
(2003)
Dev. Cell
, vol.4
, pp. 549-560
-
-
Minoshima, Y.1
-
90
-
-
0027509362
-
Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI)
-
Kishi, K., Sasaki, T., Kuroda, S., Itoh, T & Takai, Y. Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI). J. Cell Biol. 120, 1187-1195 (1993).
-
(1993)
J. Cell Biol.
, vol.120
, pp. 1187-1195
-
-
Kishi, K.1
Sasaki, T.2
Kuroda, S.3
Itoh, T.4
Takai, Y.5
-
91
-
-
0027691240
-
A rho-like protein is involved in the organisation of the contractile ring in dividing sand dollar eggs
-
Mabuchi, I. et al. A rho-like protein is involved in the organisation of the contractile ring in dividing sand dollar eggs. Zygote 1, 325-331 (1993).
-
(1993)
Zygote
, vol.1
, pp. 325-331
-
-
Mabuchi, I.1
-
92
-
-
0035577762
-
The budding yeast protein kinase lpl1/Aurora allows the absence of tension to activate the spindle checkpoint
-
Biggins, S. & Murray, A. W. The budding yeast protein kinase lpl1/Aurora allows the absence of tension to activate the spindle checkpoint. Genes Dev. 15, 3118-3129 (2001).
-
(2001)
Genes Dev.
, vol.15
, pp. 3118-3129
-
-
Biggins, S.1
Murray, A.W.2
-
93
-
-
0042170180
-
Survivin is required for stable checkpoint activation in taxol-treated HeLa cells
-
Carvalho, A., Carmena, M., Sambade, C., Earnshaw, W. C. & Wheatley, S. P. Survivin is required for stable checkpoint activation in taxol-treated HeLa cells. J. Cell Sci. 116, 2987-2998 (2003).
-
(2003)
J. Cell Sci.
, vol.116
, pp. 2987-2998
-
-
Carvalho, A.1
Carmena, M.2
Sambade, C.3
Earnshaw, W.C.4
Wheatley, S.P.5
-
94
-
-
0038376119
-
Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension
-
Lens, S. M. A. et al. Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension. EMBO J. 22, 2934-2947 (2003). References 93 and 94 use RNAi technology to show that survivin is required for the spindle-assembly checkpoint in the presence of microtubules, and for BubR1 targeting to the kinetochore.
-
(2003)
EMBO J.
, vol.22
, pp. 2934-2947
-
-
Lens, S.M.A.1
-
95
-
-
85047696924
-
Aurora-B associated protein phosphatases as negative regulators of kinase activation
-
Sugiyama, K. et al. Aurora-B associated protein phosphatases as negative regulators of kinase activation Oncogene 21, 3103-3111 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 3103-3111
-
-
Sugiyama, K.1
-
96
-
-
0035810919
-
INCENP is required for proper targeting of survivin to the centromeres and the anaphase spindle during mitosis
-
Wheatley, S. P., Carvalho, A., Vagnarelli, P. & Earnshaw, W. C. INCENP is required for proper targeting of survivin to the centromeres and the anaphase spindle during mitosis. Curr. Biol. 11, 886-890 (2001).
-
(2001)
Curr. Biol.
, vol.11
, pp. 886-890
-
-
Wheatley, S.P.1
Carvalho, A.2
Vagnarelli, P.3
Earnshaw, W.C.4
-
97
-
-
0036732808
-
Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation
-
Bolton, M. A. et al. Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation. Mol. Biol. Cell 13, 3064-3077 (2002). A thorough study of the regulation of Aurora-B kinase activity by INCENP and survivin.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 3064-3077
-
-
Bolton, M.A.1
-
98
-
-
0035862191
-
INCENP binds directly to tubulin and requires dynamic microtubules to target to the cleavage furrow
-
Wheatley, S. P., Kandels-Lewis, S. E., Adams, R. R., Ainsztein, A. M. & Earnshaw, W. C. INCENP binds directly to tubulin and requires dynamic microtubules to target to the cleavage furrow. Exp. Cell. Res. 262, 122-127 (2001).
-
(2001)
Exp. Cell. Res.
, vol.262
, pp. 122-127
-
-
Wheatley, S.P.1
Kandels-Lewis, S.E.2
Adams, R.R.3
Ainsztein, A.M.4
Earnshaw, W.C.5
-
99
-
-
0032576619
-
INCENP centromere and spindle targeting: Identification of essential conserved motifs and involvement of heterochromatin protein HP1
-
Ainsztein, A. M., Kandels-Lewis, S. E., Mackay, A. M. & Earnshaw, W. C. INCENP centromere and spindle targeting: identification of essential conserved motifs and involvement of heterochromatin protein HP1. J. Cell Biol. 143, 1763-1774 (1998).
-
(1998)
J. Cell Biol.
, vol.143
, pp. 1763-1774
-
-
Ainsztein, A.M.1
Kandels-Lewis, S.E.2
Mackay, A.M.3
Earnshaw, W.C.4
-
100
-
-
25544443164
-
AIM-1 regulates onset of cytokinesis by targeting INCENP to midzone and midbody
-
Terada, Y., Katayama, H., Tatsuka, M. & Kuriyama, R. AIM-1 regulates onset of cytokinesis by targeting INCENP to midzone and midbody. Mol. Biol. Cell 11S, 343a (2000).
-
(2000)
Mol. Biol. Cell
, vol.11 S
-
-
Terada, Y.1
Katayama, H.2
Tatsuka, M.3
Kuriyama, R.4
-
101
-
-
0037008684
-
Phosphorylation of the carboxyl terminus of inner centromere protein (INCENP) by the Aurora B kinase stimulates Aurora B kinase activity
-
Bishop, J. D. & Schumacher, J. M. Phosphorylation of the carboxyl terminus of inner centromere protein (INCENP) by the Aurora B kinase stimulates Aurora B kinase activity. J. Biol. Chem. 277, 27577-27580 (2002). Provided a clear demonstration that INCENP phosphorylation by Aurora B is part of a feedback loop that stimulates kinase activity.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 27577-27580
-
-
Bishop, J.D.1
Schumacher, J.M.2
-
102
-
-
0033082995
-
IAP family proteins - Suppressors of apoptosis
-
Deveraux, Q. L. & Reed, J. C. IAP family proteins - suppressors of apoptosis. Genes Dev. 13, 239-252 (1999).
-
(1999)
Genes Dev.
, vol.13
, pp. 239-252
-
-
Deveraux, Q.L.1
Reed, J.C.2
-
103
-
-
0034597594
-
Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype
-
Uren, A. G. et al. Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype. Curr. Biol. 10, 1319-1328 (2000).
-
(2000)
Curr. Biol.
, vol.10
, pp. 1319-1328
-
-
Uren, A.G.1
-
104
-
-
0037414775
-
Survivin enhances Aurora-B kinase activity and localizes Aurora-B in human cells
-
Chen, J. et al. Survivin enhances Aurora-B kinase activity and localizes Aurora-B in human cells. J. Biol. Chem. 278, 486-490 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 486-490
-
-
Chen, J.1
-
105
-
-
0034820448
-
Bir1/Cut17 moving from chromosome to spindle upon the loss of cohesion is required for condensation, spindle elongation and repair
-
Morishita, J. et al. Bir1/Cut17 moving from chromosome to spindle upon the loss of cohesion is required for condensation, spindle elongation and repair. Genes Cells 6, 743-763 (2001).
-
(2001)
Genes Cells
, vol.6
, pp. 743-763
-
-
Morishita, J.1
-
106
-
-
0032417221
-
Colocalization of TD-60 and INCENP throughout G2 and mitosis: Evidence for their possible interaction in signalling cytokinesis
-
Martineau-Thuillier, S., Andreassen, P. R. & Margolis, R. L. Colocalization of TD-60 and INCENP throughout G2 and mitosis: evidence for their possible interaction in signalling cytokinesis. Chromosoma (Berl.) 107, 461-470 (1998).
-
(1998)
Chromosoma (Berl.)
, vol.107
, pp. 461-470
-
-
Martineau-Thuillier, S.1
Andreassen, P.R.2
Margolis, R.L.3
-
107
-
-
0041778335
-
The mammalian passenger protein TD-60 is an RCC1 family member with an essential role in prometaphase to metaphase progression
-
Mollinari, C. et al. The mammalian passenger protein TD-60 is an RCC1 family member with an essential role in prometaphase to metaphase progression Dev. Cell 5, 295-307 (2003).
-
(2003)
Dev. Cell
, vol.5
, pp. 295-307
-
-
Mollinari, C.1
-
108
-
-
0041941573
-
An inner centromere protein that stimulates the microtubule depolymerizing activity of a Kin 1 kinesin
-
Ohi, R., Coughlin, M. L., Lane, W. S. & Mitchison, T. J. An inner centromere protein that stimulates the microtubule depolymerizing activity of a Kin1 kinesin. Dev. Cell 5, 309-321 (2003).
-
(2003)
Dev. Cell
, vol.5
, pp. 309-321
-
-
Ohi, R.1
Coughlin, M.L.2
Lane, W.S.3
Mitchison, T.J.4
-
109
-
-
0038070181
-
CSC-1: A subunit of the Aurora B kinase complex that binds to the survivin-like protein BIR-1 and the incenp-like protein ICP-1
-
Romano, A. et al. CSC-1: a subunit of the Aurora B kinase complex that binds to the survivin-like protein BIR-1 and the incenp-like protein ICP-1. J. Cell Biol. 161, 229-236 (2003).
-
(2003)
J. Cell Biol.
, vol.161
, pp. 229-236
-
-
Romano, A.1
-
110
-
-
0032213515
-
Multinuclearity and increased ploidy caused by overexpression of the aurora- and lpl1-like midbody-associated protein mitotic kinase in human cancer cells
-
Tatsuka, M. et al. Multinuclearity and increased ploidy caused by overexpression of the aurora- and lpl1-like midbody-associated protein mitotic kinase in human cancer cells. Cancer Res. 58, 4811-4816 (1998).
-
(1998)
Cancer Res.
, vol.58
, pp. 4811-4816
-
-
Tatsuka, M.1
-
111
-
-
0033756439
-
Centrosomal kinases, HsAIRK1 and HsAIRK3, are overexpressed in primary colorectal cancers
-
Takahashi, T. et al. Centrosomal kinases, HsAIRK1 and HsAIRK3, are overexpressed in primary colorectal cancers Jpn. J. Cancer Res. 91, 1007-1014 (2000).
-
(2000)
Jpn. J. Cancer Res.
, vol.91
, pp. 1007-1014
-
-
Takahashi, T.1
-
112
-
-
0031714080
-
Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation
-
Zhou, H. et al. Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nature Genet. 20, 189-193 (1998).
-
(1998)
Nature Genet.
, vol.20
, pp. 189-193
-
-
Zhou, H.1
-
113
-
-
0034025874
-
Frequent amplification of chromosomal region 20q12-q 13 in ovarian cancer
-
Tanner, M. M. et al. Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer. Clin. Cancer Res. 6, 1833-1839 (2000).
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 1833-1839
-
-
Tanner, M.M.1
-
115
-
-
0036752341
-
Duplicating dangerously: Linking centrosome duplication and aneuploidy
-
Doxsey, S. Duplicating dangerously: linking centrosome duplication and aneuploidy. Mol. Cell 10, 439-440 (2002).
-
(2002)
Mol. Cell
, vol.10
, pp. 439-440
-
-
Doxsey, S.1
-
116
-
-
0037084163
-
-/- cells
-
-/- cells. EMBO J. 21, 483-492 (2002). Presents data indicating that centrosome amplification in response to Aurora kinase overexpression arises as a result of failures in cytokinesis.
-
(2002)
EMBO J.
, vol.21
, pp. 483-492
-
-
Meraidi, P.1
Honda, R.2
Nigg, E.A.3
-
117
-
-
0037586498
-
AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol
-
Anand, S., Penrhyn-Lowe, S. & Venkitaraman, A. R. AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol. Cancer Cell 3, 51-62 (2003).
-
(2003)
Cancer Cell
, vol.3
, pp. 51-62
-
-
Anand, S.1
Penrhyn-Lowe, S.2
Venkitaraman, A.R.3
-
118
-
-
0037009435
-
Suppression of the STK15 oncogenic activity requires a transactivation-independent p53 function
-
Chen, S. S., Chang, P. C., Cheng, Y. W., Tang, F. M. & Lin, Y. S. Suppression of the STK15 oncogenic activity requires a transactivation-independent p53 function. EMBO J. 21, 4491-4499 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 4491-4499
-
-
Chen, S.S.1
Chang, P.C.2
Cheng, Y.W.3
Tang, F.M.4
Lin, Y.S.5
-
119
-
-
0029658664
-
Expression of Bcl-xL and loss of p 53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage
-
Minn, A. J., Boise, L. H. & Thompson, C. B. Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage. Genes Dev. 10, 2621-2631 (1996).
-
(1996)
Genes Dev.
, vol.10
, pp. 2621-2631
-
-
Minn, A.J.1
Boise, L.H.2
Thompson, C.B.3
-
120
-
-
0031931414
-
Characterization of the p53-dependent postmitotic checkpoint following spindle disruption
-
Lanni, J. S. & Jacks, T. Characterization of the p53-dependent postmitotic checkpoint following spindle disruption. Mol. Cell. Biol. 18, 1055-1064 (1998).
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 1055-1064
-
-
Lanni, J.S.1
Jacks, T.2
-
121
-
-
0032005132
-
p53 and pRb prevent rereplication in response to microtubule inhibitors by mediating a reversible G1 arrest
-
Khan, S. H. & Wahl, G. M. p53 and pRb prevent rereplication in response to microtubule inhibitors by mediating a reversible G1 arrest. Cancer Res. 58, 396-401 (1998).
-
(1998)
Cancer Res.
, vol.58
, pp. 396-401
-
-
Khan, S.H.1
Wahl, G.M.2
-
122
-
-
0033178452
-
p53-independent apoptosis and p53-dependent block of DNA rereplication following mitotic spindle inhibition in human cells
-
Casenghi, M. et al. p53-independent apoptosis and p53-dependent block of DNA rereplication following mitotic spindle inhibition in human cells. Exp. Cell Res. 250, 339-350 (1999).
-
(1999)
Exp. Cell Res.
, vol.250
, pp. 339-350
-
-
Casenghi, M.1
-
123
-
-
0034767429
-
Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1
-
Andreassen, P. R., Lohez, O. D., Lacroix, F. B. & Margolis, R. L. Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1. Mol. Biol. Cell 12, 1315-1328 (2001).
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 1315-1328
-
-
Andreassen, P.R.1
Lohez, O.D.2
Lacroix, F.B.3
Margolis, R.L.4
-
124
-
-
0037189527
-
Identification of Aurora kinases as RasGAP Src homology 3 domain-binding proteins
-
Gigoux, V., L'Hoste, S., Raynaud, F., Camonis, J. & Garbay, C. Identification of Aurora kinases as RasGAP Src homology 3 domain-binding proteins. J. Biol. Chem. 277, 23742-23746 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 23742-23746
-
-
Gigoux, V.1
L'Hoste, S.2
Raynaud, F.3
Camonis, J.4
Garbay, C.5
-
125
-
-
0037105758
-
Increased mitotic phosphorylation of histone H3 attributable to AIM-1/Aurora-B overexpression contributes to chromosome number instability
-
Ota, T. et al. Increased mitotic phosphorylation of histone H3 attributable to AIM-1/Aurora-B overexpression contributes to chromosome number instability. Cancer Res. 62, 5168-5177 (2002).
-
(2002)
Cancer Res.
, vol.62
, pp. 5168-5177
-
-
Ota, T.1
-
126
-
-
0024299475
-
Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+
-
Gautier, J., Norbury, C., Lohka, M., Nurse, P. & Maller J. Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+. Cell 54, 433-439 (1988).
-
(1988)
Cell
, vol.54
, pp. 433-439
-
-
Gautier, J.1
Norbury, C.2
Lohka, M.3
Nurse, P.4
Maller, J.5
-
127
-
-
0345054420
-
Purification of maturation-promoting factor, an intracellular regulator of early mitotic events
-
Lohka, M., Hayes, M. K. & Maller, J. L. Purification of maturation-promoting factor, an intracellular regulator of early mitotic events. Proc. Natl Acad. Sci. USA 85, 3009-3013 (1988).
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 3009-3013
-
-
Lohka, M.1
Hayes, M.K.2
Maller, J.L.3
-
128
-
-
0033574614
-
Mechanisms of cyclin-dependent kinase regulation: Structures of Cdks, their cyclin activators, and Cip and INK 4 inhibitors
-
Pavletich, N. P. Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors. J. Mol. Biol. 287, 821-828 (1999).
-
(1999)
J. Mol. Biol.
, vol.287
, pp. 821-828
-
-
Pavletich, N.P.1
-
129
-
-
0037135979
-
Human TPX2 is required for targeting Aurora-A kinase to the spindle
-
Kufer, T. A. et al. Human TPX2 is required for targeting Aurora-A kinase to the spindle. J. Cell Biol. 158, 617-623 (2002).
-
(2002)
J. Cell Biol.
, vol.158
, pp. 617-623
-
-
Kufer, T.A.1
|