INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis

Current Biology

Volumn 11, Issue 11, 2001, Pages 886-890

  Wheatley, Sally P ^a   Carvalho, Ana ^a,b   Vagnarelli, Paola ^a   Earnshaw, William C ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHASE; CELL DISRUPTION; CENTROMERE; CHROMOSOME PROTEIN; CHROMOSOME STRUCTURE; CYTOKINESIS; ENZYME LOCALIZATION; MAMMAL CELL; MITOSIS; PROTEIN INTERACTION; PROTEIN TARGETING; SURVIVIN; XENOPUS;

MAMMALIA; VERTEBRATA;

EID: 0035810919     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00238-X     Document Type: Article

References (21)

1. Chromosomal proteins and cytokinesis: Patterns of cleavage furrow formation and inner centromere protein positioning in mitotic heterokaryons and mid-anaphase cells
2. A dominant mutant of inner centromere protein (INCENP), a chromosomal protein, disrupts prometaphase congression and cytokinesis
3. AIM-1: A mammalian midbody-associated protein required for cytokinesis
4. Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis
5. The Survivin-like C. elegans BIR-1 protein acts with the Aurora-like kinase AIR-2 to affect chromosomes and the spindle midzone
6. The Aurora-related kinase AIR-2 recruits ZEN-4/CeMKLP1 to the mitotic spindle at metaphase and is required for cytokinesis
7. Incenp and an Aurora-like kinase form a complex essential for chromosome segregation and efficient completion of cytokinesis
8. Chromosomal passengers and the (Aurora) ABCs of mitosis
9. INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow
10. Control of apoptosis and mitotic spindle checkpoint by Survivin
11. Pleiotropic cell-division defects and apoptosis induced by interference with Survivin function
12. Chromosomal passengers: Towards an integrated view of mitosis
13. Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype
14. Human Survivin is a kinetochore-associated passenger protein
15. The INCENP antigens: Movement from the inner centromere to the midbody during mitosis
16. Telophase disk: A new mammalian mitotic organelle that bisects telophase cells with a possible function in cytokinesis
17. AIR-2: An Aurora/lpl1-related protein kinase associated with chromosomes and midbody microtubules is required for polar body extrusion and cytokinesis in Caenorhabditis elegans embryos
18. INCENP centromere and spindle targeting: Identification of essential conserved motifs and involvement of heterochromatin protein HP1
19. Essential roles of Drosophila INCENP and aurora-B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction and chromosome segregation
20. Regulation of apoptosis at cell division by p34cdc2 phosphorylation of Survivin
21. INCENP binds directly to tubulin and requires dynamic microtubules to target to the cleavage furrow