Probing the dynamics and functions of aurora B kinase in living cells during mitosis and cytokinesis

Molecular Biology of the Cell

Volumn 13, Issue 4, 2002, Pages 1099-1108

  Murata Hori, Maki ^a   Tatsuka, Masaaki ^a   Wang, Yu Li ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AURORA B KINASE; GREEN FLUORESCENT PROTEIN; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG;

ANAPHASE; ANIMAL CELL; ARTICLE; CENTROMERE; CYTOKINESIS; DEPOLYMERIZATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; EPITHELIUM CELL; MICROTUBULE; MITOSIS; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL; PROPHASE; RAT;

ANIMALS; CELL DIVISION; CELLS, CULTURED; CYCLIN B; GREEN FLUORESCENT PROTEINS; KIDNEY; LUMINESCENT PROTEINS; MICROSCOPY, FLUORESCENCE; MICROTUBULES; MITOSIS; MODELS, BIOLOGICAL; PLASMIDS; PROTEIN-SERINE-THREONINE KINASES; RATS; RECOMBINANT FUSION PROTEINS; RHODAMINES; TIME FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TUBULIN;

ANIMALIA;

EID: 0036223382     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.01-09-0467     Document Type: Article

References (42)

1. INCENP binds the aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow
2. Essential roles of Drosophila inner centromere protein (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetocore disjunction, and chromosome segregation
3. Pavarotti encodes a kinesin-like protein required to organize the central spindle and contractile ring for cytokinesis
4. Telophase disc: A new mammalian mitotic organelle that bisects telophase cells with a possible function in cytokinesis
5. GFP tagging reveals human Polo-like kinase I at the kinetochore/centromere region of mitotic chromosomes
6. A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
7. Up-regulation of cdc2 protein during paclitaxel-induced apoptosis
8. Synthesis and application of functionally diverse 2, 6, 9-trisubstituted purine libraries as CDK inhibitors
9. Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores
10. The inner centromere protein (INCENP) antigens: Movement from inner centromere to midbody during mitosis
11. Defective chromosome segregation, microtubule bundling and nuclear bridging in inner centromere protein gene (incenp)-disrupted mice
12. Chromosomal proteins and cytokinsis: Pattern of cleavage furrow formation and inner centromere protein positioning in mitotic heterokaryons and mid-anaphase cells
13. Regulation of yeast chromosome segregation by Ipl1 protein kinase and type 1 protein phosphatase
14. Drosophila Aurora B kinase is required for histone H3 phosphorylation and condensing recruitment during chromosome condensation and to organize the central spindle during cytokinesis
15. Aurora/Ipl1p-related protein kinase, a new oncogenic family of mitotic serine-threonine kinases
16. The Xenopus lavies aurora/Ipl1prelated kinase pEg2 participates in the stability of the bipolar mitotic spindle
17. Cyclin is degraded by the ubiquitin pathway
18. Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles
19. Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc/PP1 phosphatase in budding yeast and nematodes
20. Incenp and an Aurora-like kinase form a complex essential for chromosome segregation and efficient completion of cytokinesis
21. Feedback control of mitosis in budding yeast
22. Identification of a human mitotic checkpoint gene: hsMAD2
23. A dominant mutant of inner centromere protein (INCENP), a chromosomal passenger protein, disrupts prometaphase congression and cytokinesis
24. Culturing cells on the microscope stage
25. Colocalization of TD-60 and INCENP throughout G2 and mitosis: Evidence for their possible interaction in signaling cytokinesis
26. Myosin II regulatory light chain as a novel substrate for AIM-1, an aurora/Ipl1p-related kinase from rat
27. A plus-end-directed motor enzymes that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles
28. A nematode kinesin required for cleavage furrow advancement
29. Cytokinesis and midzone microtubule organization in Caenorhabditis elegans require the kinesin-like protein ZEN-4
30. The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly
31. AIR-2: An Aurora/Ipl1-related protein kinase associated with chromosomes and midbody microtubules is required for polar body extrusion and cytokinesis in Caenorhabditis elegans embryos
32. The aurora-related kinase AIR-2 recruits ZEN-4/CeMKLP1 to the mitotic spindle at metaphase and is required for cytokinesis
33. Human survivin is a kinetochore-associated passenger protein
34. Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells
35. AIM-1: A mammalian midbody-associated protein required for cytokinesis
36. Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype
37. Fluorescence microscopic analysis of cytoskeletal organization and dynamics
38. Localization of Mad2 to kinetochores depends on microtubule attachment, not tension
39. CDK1 inactivation regulates anaphase spindle dynamics and cytokinesis in vivo
40. Incenp binds directly to tubulin and requires dynamic microtubules to target to the cleavage furrow
41. Inhibition of chromosomal separation provides insights into cleavage furrow stimulation in cultured epithelial cells
42. Midzone microtubule bundles are continuously required for cytokinesis in cultured epithelial cells