The S. pombe aurora-related kinase Ark1 associates with mitotic structures in a stage dependent manner and is required for chromosome segregation

Journal of Cell Science

Volumn 114, Issue 24, 2001, Pages 4371-4384

  Petersen, Janni ^a   Paris, Jeannie ^a   Willer, Martin ^a   Philippe, Michel ^a   Hagan, Iain M ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Aurora; Histone H3; INCENP; Mitosis; S. pombe

Indexed keywords

EPITOPE; HISTONE H3; PHOSPHOTRANSFERASE; SERINE;

ANAPHASE; ARTICLE; CELL CYCLE; CELL CYCLE G2 PHASE; CENTROMERE; CHROMATIN; CHROMOSOME CONDENSATION; CHROMOSOME SEGREGATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINESIS; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EXTRACT; GENE LOCATION; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; MEIOSIS; METAZOON; MITOSIS; MITOSIS SPINDLE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN RESTRICTION; PROTEIN STRUCTURE; REDUCTION; SCHIZOSACCHAROMYCES POMBE; SPINDLE POLE BODY; YEAST CELL;

ANAPHASE; ANIMALS; CELL CYCLE; CELL CYCLE PROTEINS; CENTROMERE; CHROMATIN; CHROMOSOME SEGREGATION; FUNGAL PROTEINS; G1 PHASE; GENE DELETION; HISTONES; KINESIN; MITOSIS; MITOTIC SPINDLE APPARATUS; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; SCHIZOSACCHAROMYCES POMBE PROTEINS; SERINE; XENOPUS; XENOPUS PROTEINS;

METAZOA; SACCHAROMYCES; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE;

EID: 0035694554     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (64)

1. Pavarotti encodes a kinesin-like protein required to organize the central spindle and contractile ring for cytokinesis
2. Chromosomal passengers and the (aurora) ABCs of mitosis
3. Essential roles of Drosophila inner centromere protein (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation
4. Role of polo kinase and Mid1p in determining the site of cell division in fission yeast
5. Control of S-phase periodic transcription in the fission yeast mitotic cycle
6. The conserved protein kinase Ip11 regulates microtubule binding to kinetochores in budding yeast
7. A homologue of the Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
8. Characterization of Schizosaccharomyces pombe Hus1: A PCNA-related protein that associates with Rad1 and Rad9
9. Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in Yeast
10. Signaling to chromatin through histone modifications
11. The inner centromere protein (INCENP) antigens: Movement from inner centromere to midbody during mitosis
12. Vectors for the expression of tagged proteins in Schizosaccharomyces pombe
13. Flp1, a fission yeast orthologue of the S. cerevisiae CDC14 gene, is not required for cyclin degradation or rum1p stabilisation at the end of mitosis
14. Mutations in the bimC box of Cut7 indicate divergence of regulation within the bimC family of kinesin related proteins
15. Chromosomal passenger proteins: Towards an integrated view of mitosis
16. Chromosomal proteins and cytokinesis: Patterns of cleavage furrow formation and inner centromere protein positioning in mitotic heterokaryons and mid-anaphase cells
17. Type-1 protein phosphatase acts in opposition to Ipl1 protein-kinase in regulating yeast chromosome segregation
18. Cell cycle-dependent specific positioning and clustering of centromeres and telomeres in fission yeast
19. Drosophila aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis
20. Aurora/Ip11p-related kinases, a new oncogenic family of mitotic serine-threonine kinases
21. The Xenopus laevis aurora-related protein kinase pEg2 associates with and phosphorylates the kinesin-related protein XlEg5
22. The mechanism and control of cytokinesis
23. Mutations in Aurora prevent centrosome separation leading to the formation of monopolar spindles
24. A novel mammalian, mitotic spindle-associated kinase is related to yeast and fly chromosome segregation regulators
25. Kinesin-related Cut7 protein associates with mitotic and meiotic spindles in fission yeast
26. + associates with the fission yeast spindle pole body and is essential for viability
27. Fluorescence microscopy in Yeast
28. Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation
29. Mitotic phosphorylation of histone H3 is governed by Ip11/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes
30. Incenp and an aurora-like kinase form a complex essential for chromosome segregation and efficientcompletion of cytokinesis
31. Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5
32. Downregulation of an AIM-1 kinase couples with megakaryocytic polyploidization of human hematopoietic cells
33. Slil5 associates with the Ip11 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiae
34. Nmt1 of Fission Yeast - A Highly Transcribed Gene Completely Repressed By Thiamine
35. Thiamine-repressible expression vectors pREP and pRIP for fission yeast
36. Molecular genetic analysis of fission yeast Schizosaccharomyces pombe
37. Plol kinase recruitment to the spindle pole body and its role in cell division in Schizosaccharomyces pombe
38. Splitting the chromosome: Cutting the ties that bind sister chromatids
39. Mitotic kinases as regulators of cell division and its checkpoints
40. Cold-sensitive and caffeine-supersensitive mutants of the schizosaccharomyces-pombe dis genes implicated in sister chromatid separation during mitosis
41. The fission yeast dis2+ gene required for chromosome disjoining encodes one of 2 putative type-1 protein phosphatases
42. F-actin distribution and function during sexual differentiation in Schizosaccharomyces pombe
43. The KEN box: An APC recognition signal distinct from the D box targeted by Cdhl
44. S. pombe Pbh1p: An inhibitor of apoptosis domain containing protein is essential for chromosome segregation
45. cdc10 function
46. The Xenopus protein kinase PEg2 associates with the centrosome in a cell cycle-dependent manner, binds to spindle microtubules and is involved in bipolar spindle assembly
47. Regulation of Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p
48. A human condensin complex containing hCAP-C hCAP-E and CNAP1, a homolog of Xenopus XCAP-D2, colocaliszes with phosphorylated histone H3 during the early stage of mitotic chromosome condensation
49. AIR-2: An aurora/Ip11-related kinase associated with chromosomes and midbody microtubules is required for polar body extrusion and cytokinesis in Caenorhabditis elegans
50. The aurora-related kinase AIR-2 recruits ZEN-4/CeMKLP1 to the mitotic spindle at metaphase and is required for cytokinesis
51. The aurora-related kinase AIR-2 recruits ZEN-4/CeMKLP1 to the mitotic spindle at metaphase and is required for cytokinesis
52. Two kinds of BIR-containing protein - Inhibitors of apoptosis, or required for mitosis
53. Identification of an epitope on the p-proteins and v-proteins of simian-virus 5 that distinguishes between 2 isolates with different biological characteristics
54. The role of Plol kinase in mitotic commitment and septation in Schizosaccharomyces pombe
55. Survivin and the inner centromere protein INCENP show similar cell cycle localization and gene knockout phenotype
56. Kinesin related proteins at mitotic spindle poles - Function and regulation
57. The JIL-1 tandem kinase mediates histone H3 phosphorylation and is required for maintenance of chromatin structure in Drosophila
58. Phosphorylation of histone H3 at serine 10 is correlated with chromosome condensation during mitosis and meiosis in Tetrahymena
59. Phosphorylation of histone H3 is required for proper chromosome condensation and segregation
60. The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation
61. The spindle: A dynamic assembly of microtubules and motors
62. Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal-antibodies
63. Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events