INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavege furrow

Current Biology

Volumn 10, Issue 17, 2000, Pages 1075-1078

  Adams, R R ^a   Wheatleya, S P ^a   Gouldsworthy, A M ^a   Kandels Lewis, S E ^a   Carmena, M ^a   Smythe, C ^a   Gerloff, D L ^a   Earnshaw, W C ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AURORA KINASE; CYTOSKELETON; IN VITRO CULTURE; INNER CENTROMERE PROTEIN; MITOSIS; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN SERINE THREONINE KINASE; XENOPUS;

EID: 0034618724     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(00)00673-4     Document Type: Article

References (21)

1. Chromosomal passengers: Toward an integrated view of mitosis
2. The inner centromere protein (INCENP) antigens: Movement from inner centromere to midbody during mitosis
3. AIM-1: A mammalian midbody-associated protein required for cytokinesis
4. Aurora/Ipl1p-related kinases, a new oncogenic family of mitotic serine-threonine kinases
5. Telophase disc: A new mammalian mitotic organelle that bisects telophase cells with a possible function in cytokinesis
6. A dominant mutant of inner centromere protein (INCENP), a chromosomal protein, disrupts prometaphase congression and cytokinesis
7. Defective chromosome segregation, microtubule bundling and nuclear bridging in inner centromere protein gene (Incenp)-disrupted mice
8. AIR-2: An Aurora/Ipl1-related protein kinase associated with chromosomes and midbody microtubules is required for polar body extrusion and cytokinesis in Caenorhabditis elegans embryos
9. The Aurora/Ipl1p kinase family: Regulators of chromosome segregation and cytokinesis
10. The Xenopus laevis aurora-related protein kinase pEg2 associates with and phosphorylates the kinesin-related protein XIEg5
11. Cyclin is degraded by the ubiquitin pathway
12. The KEN box: An APC recognition signal distinct from the D box targeted by Cdh1
13. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
14. Sli15 associates with the ipl1 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiae
15. The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast
16. Type 1 protein phosphatase acts in opposition to IpL1 protein kinase in regulating yeast chromosome segregation
17. Chromosomal proteins and cytokinesis: Patterns of cleavage furrow formation and inner centromere protein positioning in mitotic heterokaryons and mid-anaphase cells
18. The INCENPs: Structural and functional analysis of a family of chromosome passenger proteins
19. Blasticidin S-resistance gene (bsr): A novel selectable marker for mammalian cells
20. Multinuclearity and increased ploidy caused by overexpression of the aurora-and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells
21. MultiCoil: A program for predicting two-and three-stranded coiled coils