메뉴 건너뛰기




Volumn 284, Issue 4 53-4, 2003, Pages

Cell death induced by acute renal injury: A perspective on the contributions of apoptosis and necrosis

Author keywords

Molecular components; Renal ischemia; Renal tubular epithelial cells; Signal transduction; Therapeutic approaches

Indexed keywords

ENDONUCLEASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; NITRIC OXIDE SYNTHASE; OSTEOPONTIN; PHOSPHOLIPASE; PROTEIN BCL 2; PROTEIN KINASE;

EID: 0037376701     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00284.2002     Document Type: Review
Times cited : (342)

References (257)
  • 1
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adams JM and Cory S. The Bcl-2 protein family: arbiters of cell survival. Science 281: 1322-1326, 1998.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 2
    • 0035146929 scopus 로고    scopus 로고
    • Life-or-death decisions by the Bcl-2 protein family
    • Adams JM and Cory S. Life-or-death decisions by the Bcl-2 protein family. Trends Biochem Sci 26: 61-66, 2001.
    • (2001) Trends Biochem Sci , vol.26 , pp. 61-66
    • Adams, J.M.1    Cory, S.2
  • 3
    • 0035369143 scopus 로고    scopus 로고
    • The mitochondrial apoptosome: A killer unleashed by the cytochrome seas
    • Adrain C and Martin SJ. The mitochondrial apoptosome: a killer unleashed by the cytochrome seas. Trends Biochem Sci 26: 390-397, 2001.
    • (2001) Trends Biochem Sci , vol.26 , pp. 390-397
    • Adrain, C.1    Martin, S.J.2
  • 4
    • 0034622238 scopus 로고    scopus 로고
    • Morphological and biochemical assessment of DNA damage and apoptosis in Down syndrome and Alzheimer disease, and effect of postmortem tissue archival on TUNEL
    • Anderson AJ, Stoltzner S, Lai F, Su J, and Nixon RA. Morphological and biochemical assessment of DNA damage and apoptosis in Down syndrome and Alzheimer disease, and effect of postmortem tissue archival on TUNEL. Neurobiol Aging 21: 511-524, 2000.
    • (2000) Neurobiol Aging , vol.21 , pp. 511-524
    • Anderson, A.J.1    Stoltzner, S.2    Lai, F.3    Su, J.4    Nixon, R.A.5
  • 5
    • 1542442500 scopus 로고
    • Micropuncture study of acute renal failure following temporary renal ischemia in the rat
    • Arendshorst WJ, Finn WF, and Gottschalk CW. Micropuncture study of acute renal failure following temporary renal ischemia in the rat. Kidney Int Suppl 6: S100-S105, 1976.
    • (1976) Kidney Int Suppl , vol.6
    • Arendshorst, W.J.1    Finn, W.F.2    Gottschalk, C.W.3
  • 6
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi A and Dixit VM. Death receptors: signaling and modulation. Science 281: 1305-1308, 1998.
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 11
    • 0035199934 scopus 로고    scopus 로고
    • Renal ischemic injury results in permanent damage to peritubular capillaries and influences long-term function
    • Basile DP, Donohoe D, Roethe K, and Osborn JL. Renal ischemic injury results in permanent damage to peritubular capillaries and influences long-term function. Am J Physiol Renal Physiol 281: F887-F899, 2001.
    • (2001) Am J Physiol Renal Physiol , vol.281
    • Basile, D.P.1    Donohoe, D.2    Roethe, K.3    Osborn, J.L.4
  • 12
    • 0030848745 scopus 로고    scopus 로고
    • Expression of bcl- 2 and bax in regenerating rat renal tubules following ischemic injury
    • Basile DP, Liapis H, and Hammerman MR. Expression of bcl-2 and bax in regenerating rat renal tubules following ischemic injury. Am J Physiol Renal Physiol 272: F640-F647, 1997.
    • (1997) Am J Physiol Renal Physiol , vol.272
    • Basile, D.P.1    Liapis, H.2    Hammerman, M.R.3
  • 13
    • 0036205657 scopus 로고    scopus 로고
    • DNase I-like endonuclease in rat kidney cortex that is activated during ischemia/reperfusion injury
    • Basnakian AG, Ueda N, Kaushal GP, Mikhailova MV, and Shah SV. DNase I-like endonuclease in rat kidney cortex that is activated during ischemia/reperfusion injury. J Am Soc Nephrol 13: 1000-1007, 2002.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1000-1007
    • Basnakian, A.G.1    Ueda, N.2    Kaushal, G.P.3    Mikhailova, M.V.4    Shah, S.V.5
  • 14
    • 0033793564 scopus 로고    scopus 로고
    • Review of current evidence for apoptosis after spinal cord injury
    • Beattie MS, Farooqui AA, and Bresnahan JC. Review of current evidence for apoptosis after spinal cord injury. J Neurotrauma 17: 915-925, 2000.
    • (2000) J Neurotrauma , vol.17 , pp. 915-925
    • Beattie, M.S.1    Farooqui, A.A.2    Bresnahan, J.C.3
  • 18
  • 20
    • 0027156739 scopus 로고
    • Mechanisms of ischemic acute renal failure
    • Bonventre JV. Mechanisms of ischemic acute renal failure. Kidney Int 43: 1160-1178, 1993.
    • (1993) Kidney Int , vol.43 , pp. 1160-1178
    • Bonventre, J.V.1
  • 21
    • 0024238881 scopus 로고
    • Mediators of ischemic renal injury
    • Bonventre JV. Mediators of ischemic renal injury. Annu Rev Med 39: 531-544, 1988.
    • (1988) Annu Rev Med , vol.39 , pp. 531-544
    • Bonventre, J.V.1
  • 24
    • 0037062989 scopus 로고    scopus 로고
    • Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment
    • Brown S, Heinisch I, Ross E, Shaw K, Buckley CD, and Savill J. Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment. Nature 418: 200-203, 2002.
    • (2002) Nature , vol.418 , pp. 200-203
    • Brown, S.1    Heinisch, I.2    Ross, E.3    Shaw, K.4    Buckley, C.D.5    Savill, J.6
  • 25
    • 0027724039 scopus 로고
    • Apoptosis and necrosis. Basic types and mechanisms of cell death
    • Buja LM, Eigenbrodt ML, and Eigenbrodt EH. Apoptosis and necrosis. Basic types and mechanisms of cell death. Arch Pathol Lab Med 117: 1208-1214, 1993.
    • (1993) Arch Pathol Lab Med , vol.117 , pp. 1208-1214
    • Buja, L.M.1    Eigenbrodt, M.L.2    Eigenbrodt, E.H.3
  • 26
    • 0026342111 scopus 로고
    • Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity
    • Butcher EC. Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 67: 1033-1036, 1991.
    • (1991) Cell , vol.67 , pp. 1033-1036
    • Butcher, E.C.1
  • 27
    • 0028890707 scopus 로고
    • Sodium-mediated cell swelling is associated with irreversible damage in isolated hepatocytes exposed to hypoxia or mitochondrial toxins
    • Carini R, Autelli R, Bellomo G, Dianzani MU, and Albano E. Sodium-mediated cell swelling is associated with irreversible damage in isolated hepatocytes exposed to hypoxia or mitochondrial toxins. Biochem Biophys Res Commun 206: 180-185, 1995.
    • (1995) Biochem Biophys Res Commun , vol.206 , pp. 180-185
    • Carini, R.1    Autelli, R.2    Bellomo, G.3    Dianzani, M.U.4    Albano, E.5
  • 29
    • 0036190270 scopus 로고    scopus 로고
    • Meprin, a brushborder enzyme, plays an important role in hypoxic/ischemic acute renal tubular injury in rats
    • Carmago S, Shah SV, and Walker PD. Meprin, a brushborder enzyme, plays an important role in hypoxic/ischemic acute renal tubular injury in rats. Kidney Int 61: 959-966, 2002.
    • (2002) Kidney Int , vol.61 , pp. 959-966
    • Carmago, S.1    Shah, S.V.2    Walker, P.D.3
  • 31
    • 0034321532 scopus 로고    scopus 로고
    • Pathophysiologic role of selectins and their ligands in ischemia reperfusion injury
    • Chamoun F, Burne M, O'Donnell M, and Rabb H. Pathophysiologic role of selectins and their ligands in ischemia reperfusion injury. Front Biosci 5: E103-E109, 2000.
    • (2000) Front Biosci , vol.5
    • Chamoun, F.1    Burne, M.2    O'Donnell, M.3    Rabb, H.4
  • 32
    • 0031918223 scopus 로고    scopus 로고
    • BCL-2 family: Regulators of cell death
    • Chao DT and Korsmeyer SJ. BCL-2 family: regulators of cell death. Annu Rev Immunol 16: 395-419, 1998.
    • (1998) Annu Rev Immunol , vol.16 , pp. 395-419
    • Chao, D.T.1    Korsmeyer, S.J.2
  • 34
    • 0030978140 scopus 로고    scopus 로고
    • Alpha-melanocyte-stimulating hormone protects against renal injury after ischemia in mice and rats
    • Chiao H, Kohda Y, McLeroy P, Craig L, Housini I, and Star R. Alpha-melanocyte-stimulating hormone protects against renal injury after ischemia in mice and rats. J Clin Invest 99: 1165-1172, 1997.
    • (1997) J Clin Invest , vol.99 , pp. 1165-1172
    • Chiao, H.1    Kohda, Y.2    McLeroy, P.3    Craig, L.4    Housini, I.5    Star, R.6
  • 35
    • 0026788002 scopus 로고
    • Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation
    • Cohen GM, Sun XM, Snowden RT, Dinsdale D, and Skilleter DN. Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation. Biochem J 286: 331-334, 1992.
    • (1992) Biochem J , vol.286 , pp. 331-334
    • Cohen, G.M.1    Sun, X.M.2    Snowden, R.T.3    Dinsdale, D.4    Skilleter, D.N.5
  • 36
    • 0029114238 scopus 로고
    • Increased nitric oxide synthase activity despite lack of response to endothelium-dependent vasodilators in postischemic acute renal failure in rats
    • Conger J, Robinette J, Villar A, Raij L, and Shultz P. Increased nitric oxide synthase activity despite lack of response to endothelium-dependent vasodilators in postischemic acute renal failure in rats. J Clin Invest 96: 631-638, 1995.
    • (1995) J Clin Invest , vol.96 , pp. 631-638
    • Conger, J.1    Robinette, J.2    Villar, A.3    Raij, L.4    Shultz, P.5
  • 37
    • 0029381533 scopus 로고
    • Abnormal vascular function following ischemia-reperfusion injury
    • Conger JD and Weil JV. Abnormal vascular function following ischemia-reperfusion injury. J Investig Med 43: 431-442, 1995.
    • (1995) J Investig Med , vol.43 , pp. 431-442
    • Conger, J.D.1    Weil, J.V.2
  • 38
    • 0033565557 scopus 로고    scopus 로고
    • The mitochondrial permeability transition pore and its role in cell death
    • Crompton M. The mitochondrial permeability transition pore and its role in cell death. Biochem J 341: 233-249, 1999.
    • (1999) Biochem J , vol.341 , pp. 233-249
    • Crompton, M.1
  • 40
    • 0035049537 scopus 로고    scopus 로고
    • Bcl-X(L) translocation in renal tubular epithelial cells in vitro protects distal cells from oxidative stress
    • Cuttle L, Zhang XJ, Endre ZH, Winterford C, and Gobe GC. Bcl-X(L) translocation in renal tubular epithelial cells in vitro protects distal cells from oxidative stress. Kidney Int 59: 1779-1788, 2001.
    • (2001) Kidney Int , vol.59 , pp. 1779-1788
    • Cuttle, L.1    Zhang, X.J.2    Endre, Z.H.3    Winterford, C.4    Gobe, G.C.5
  • 42
    • 0037096712 scopus 로고    scopus 로고
    • Apoptosis and inflammation in renal reperfusion injury
    • Daemen MA, de Vries B, and Buurman WA. Apoptosis and inflammation in renal reperfusion injury. Transplantation 73: 1693-1700, 2002.
    • (2002) Transplantation , vol.73 , pp. 1693-1700
    • Daemen, M.A.1    De Vries, B.2    Buurman, W.A.3
  • 44
    • 0033679661 scopus 로고    scopus 로고
    • Modeling ischemia in vitro: Selective depletion of adenine and guanine nucleotide pools
    • Dagher P, Modeling ischemia in vitro: selective depletion of adenine and guanine nucleotide pools. Am J Physiol Cell Physiol 279: C1270-C1277, 2000.
    • (2000) Am J Physiol Cell Physiol , vol.279
    • Dagher, P.1
  • 45
    • 0036156658 scopus 로고    scopus 로고
    • Single injection of naked plasmid encoding hepatocyte growth factor prevents cell death and ameliorates acute renal failure in mice
    • Dai C, Yang J, and Liu Y. Single injection of naked plasmid encoding hepatocyte growth factor prevents cell death and ameliorates acute renal failure in mice. J Am Soc Nephrol 13: 411-422, 2002.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 411-422
    • Dai, C.1    Yang, J.2    Liu, Y.3
  • 46
    • 0034791614 scopus 로고    scopus 로고
    • Apoptosis in acute renal failure
    • De Broe ME, Apoptosis in acute renal failure. Nephrol Dial Transplant 16: 23-26, 2001.
    • (2001) Nephrol Dial Transplant , vol.16 , pp. 23-26
    • De Broe, M.E.1
  • 47
    • 0032848771 scopus 로고    scopus 로고
    • MAPK activation determines renal epithelial cell survival during oxidative injury
    • DiMari JF, Davis R, and Safirstein RL. MAPK activation determines renal epithelial cell survival during oxidative injury. Am J Physiol Renal Physiol 277: F195-F203, 1999.
    • (1999) Am J Physiol Renal Physiol , vol.277
    • DiMari, J.F.1    Davis, R.2    Safirstein, R.L.3
  • 49
    • 0030663451 scopus 로고    scopus 로고
    • Internucleosomal DNA cleavage triggered by plasma membrane damage during necrotic cell death. Involvement of serine but not cysteine proteases
    • Dong Z, Saikumar P, Weinberg JM, and Venkatachalam MA. Internucleosomal DNA cleavage triggered by plasma membrane damage during necrotic cell death. Involvement of serine but not cysteine proteases. Am J Pathol 151: 1205-1213, 1997.
    • (1997) Am J Pathol , vol.151 , pp. 1205-1213
    • Dong, Z.1    Saikumar, P.2    Weinberg, J.M.3    Venkatachalam, M.A.4
  • 50
    • 0034108338 scopus 로고    scopus 로고
    • Early renal ischemia, with or without reperfusion, activates NF-κB and increases TNF-α bioactivity in the kidney
    • Donnahoo K, Meldrum D, Shenkar R, Chung C, Abraham E, and Harken A. Early renal ischemia, with or without reperfusion, activates NF-κB and increases TNF-α bioactivity in the kidney. J Urol 163: 1328-1332, 2000.
    • (2000) J Urol , vol.163 , pp. 1328-1332
    • Donnahoo, K.1    Meldrum, D.2    Shenkar, R.3    Chung, C.4    Abraham, E.5    Harken, A.6
  • 51
    • 0033162780 scopus 로고    scopus 로고
    • Review article: The role of tumor necrosis factor in renal ischemiareperfusion injury
    • Donnahoo K, Shames B, Harken A, and Meldrum D. Review article: the role of tumor necrosis factor in renal ischemiareperfusion injury. J Urol 162: 196-203, 1999.
    • (1999) J Urol , vol.162 , pp. 196-203
    • Donnahoo, K.1    Shames, B.2    Harken, A.3    Meldrum, D.4
  • 52
    • 0034616945 scopus 로고    scopus 로고
    • Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
    • Du C, Fang M, Li Y, Li L, and Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102: 33-42, 2000.
    • (2000) Cell , vol.102 , pp. 33-42
    • Du, C.1    Fang, M.2    Li, Y.3    Li, L.4    Wang, X.5
  • 55
    • 0032780169 scopus 로고    scopus 로고
    • Role of caspases in hypoxia-induced necrosis of rat renal proximal tubules
    • Edelstein CL, Shi Y, and Schrier RW. Role of caspases in hypoxia-induced necrosis of rat renal proximal tubules. J Am Soc Nephrol 10: 1940-1949, 1999.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 1940-1949
    • Edelstein, C.L.1    Shi, Y.2    Schrier, R.W.3
  • 57
    • 0031888955 scopus 로고    scopus 로고
    • A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
    • Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, and Nagata S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 391: 43-50, 1998.
    • (1998) Nature , vol.391 , pp. 43-50
    • Enari, M.1    Sakahira, H.2    Yokoyama, H.3    Okawa, K.4    Iwamatsu, A.5    Nagata, S.6
  • 59
    • 0036182380 scopus 로고    scopus 로고
    • Calcium and oxidative stress: From cell signaling to cell death
    • Ermak G and Davies KJ. Calcium and oxidative stress: from cell signaling to cell death. Mol Immunol 38: 713-721, 2002.
    • (2002) Mol Immunol , vol.38 , pp. 713-721
    • Ermak, G.1    Davies, K.J.2
  • 60
    • 0019848111 scopus 로고
    • Myocardial ischemia: The pathogenesis of irreversible cell injury in ischemia
    • Farber JL, Chien KR, and Mittnacht S Jr. Myocardial ischemia: the pathogenesis of irreversible cell injury in ischemia. Am J Pathol 102: 271-281, 1981.
    • (1981) Am J Pathol , vol.102 , pp. 271-281
    • Farber, J.L.1    Chien, K.R.2    Mittnacht S., Jr.3
  • 63
    • 0035736259 scopus 로고    scopus 로고
    • Organelle-specific initiation of cell death pathways
    • Ferri KF and Kroemer G. Organelle-specific initiation of cell death pathways. Nat Cell Biol 3: E255-E263, 2001.
    • (2001) Nat Cell Biol , vol.3
    • Ferri, K.F.1    Kroemer, G.2
  • 65
    • 0016822758 scopus 로고
    • Pathogenesis of oliguria in acute renal failure
    • Finn WF, Arendshorst WJ, and Gottschalk CW. Pathogenesis of oliguria in acute renal failure. Circ Res 36: 675-681, 1975.
    • (1975) Circ Res , vol.36 , pp. 675-681
    • Finn, W.F.1    Arendshorst, W.J.2    Gottschalk, C.W.3
  • 67
    • 84915943405 scopus 로고
    • Cell deaths in normal vertebrate ontogeny
    • Glucksmann A. Cell deaths in normal vertebrate ontogeny. Biol Rev 26: 59-86, 1951.
    • (1951) Biol Rev , vol.26 , pp. 59-86
    • Glucksmann, A.1
  • 69
    • 0032955415 scopus 로고    scopus 로고
    • Duality of nitric oxide in acute renal injury
    • Goligorsky MS and Noiri E. Duality of nitric oxide in acute renal injury. Semin Nephrol 19: 263-271, 1999.
    • (1999) Semin Nephrol , vol.19 , pp. 263-271
    • Goligorsky, M.S.1    Noiri, E.2
  • 70
    • 0033534446 scopus 로고    scopus 로고
    • Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death
    • Gross A, Yin XM, Wang K, Wei MC, Jockel J, Milliman C, Erdjument-Bromage H, Tempst P, and Korsmeyer SJ. Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death. J Biol Chem 274: 1156-1163, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 1156-1163
    • Gross, A.1    Yin, X.M.2    Wang, K.3    Wei, M.C.4    Jockel, J.5    Milliman, C.6    Erdjument-Bromage, H.7    Tempst, P.8    Korsmeyer, S.J.9
  • 72
    • 0033598713 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion
    • Ha HC and Snyder SH. Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion. Proc Natl Acad Sci USA 96: 13978-13982, 1999.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13978-13982
    • Ha, H.C.1    Snyder, S.H.2
  • 73
    • 78651025304 scopus 로고
    • Proliferation, differentiation and degeneration in the spinal ganglia of the chick embryo under normal and experimental conditions
    • Hamburger VRLM. Proliferation, differentiation and degeneration in the spinal ganglia of the chick embryo under normal and experimental conditions. J Exp Zool 111: 457-501, 1975.
    • (1975) J Exp Zool , vol.111 , pp. 457-501
    • Hamburger, V.R.L.M.1
  • 74
    • 0031826418 scopus 로고    scopus 로고
    • Growth factors and apoptosis in acute renal injury
    • Hammerman MR. Growth factors and apoptosis in acute renal injury. Curr Opin Nephrol Hypertens 7: 419-424, 1998.
    • (1998) Curr Opin Nephrol Hypertens , vol.7 , pp. 419-424
    • Hammerman, M.R.1
  • 75
    • 0031053588 scopus 로고    scopus 로고
    • New treatments for acute renal failure: Growth factors and beyond
    • Hammerman MR. New treatments for acute renal failure: growth factors and beyond. Curr Opin Nephrol Hypertens 6: 7-9, 1997.
    • (1997) Curr Opin Nephrol Hypertens , vol.6 , pp. 7-9
    • Hammerman, M.R.1
  • 76
    • 0029018649 scopus 로고
    • Growth factor gene expression in tubular epithelial injury
    • Hammerman MR and Miller SB. Growth factor gene expression in tubular epithelial injury. Curr Opin Nephrol Hypertens 4: 258-262, 1995.
    • (1995) Curr Opin Nephrol Hypertens , vol.4 , pp. 258-262
    • Hammerman, M.R.1    Miller, S.B.2
  • 77
    • 0028471151 scopus 로고
    • Therapeutic use of growth factors in renal failure
    • Hammerman MR and Miller SB. Therapeutic use of growth factors in renal failure. J Am Soc Nephrol 5: 1-11, 1994.
    • (1994) J Am Soc Nephrol , vol.5 , pp. 1-11
    • Hammerman, M.R.1    Miller, S.B.2
  • 78
    • 0030976895 scopus 로고    scopus 로고
    • A sequential two-step mechanism for the production of the mature p17:p12 form of caspase- 3 in vitro
    • Han Z, Hendrickson EA, Bremner TA, and Wyche JH, A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro. J Biol Chem 272: 13432-13436, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 13432-13436
    • Han, Z.1    Hendrickson, E.A.2    Bremner, T.A.3    Wyche, J.H.4
  • 81
    • 0034599085 scopus 로고    scopus 로고
    • Toward antiapoptosis as a new treatment modality
    • Haunstetter A and Izumo S. Toward antiapoptosis as a new treatment modality. Circ Res 86: 371-376, 2000.
    • (2000) Circ Res , vol.86 , pp. 371-376
    • Haunstetter, A.1    Izumo, S.2
  • 82
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner MO. The biochemistry of apoptosis. Nature 407: 770-776, 2000.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 83
    • 0030954386 scopus 로고    scopus 로고
    • 2 in the rat insulinsecreting cell line CRI-G 1
    • 2 in the rat insulinsecreting cell line CRI-G1. J Physiol 501: 59-66, 1997.
    • (1997) J Physiol , vol.501 , pp. 59-66
    • Herson, P.S.1    Ashford, M.L.2
  • 84
    • 0033534690 scopus 로고    scopus 로고
    • Hydrogen peroxide induces intracellular calcium overload by activation of a non-selective cation channel in an insulinsecreting cell line
    • Herson PS, Lee K, Pinnock RD, Hughes J, and Ashford ML. Hydrogen peroxide induces intracellular calcium overload by activation of a non-selective cation channel in an insulinsecreting cell line. J Biol Chem 274: 833-841, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 833-841
    • Herson, P.S.1    Lee, K.2    Pinnock, R.D.3    Hughes, J.4    Ashford, M.L.5
  • 86
    • 0033635733 scopus 로고    scopus 로고
    • BH3-only proteins-essential initiators of apoptotic cell death
    • Huang DC and Strasser A. BH3-only proteins-essential initiators of apoptotic cell death. Cell 103: 839-842, 2000.
    • (2000) Cell , vol.103 , pp. 839-842
    • Huang, D.C.1    Strasser, A.2
  • 87
    • 0027955562 scopus 로고
    • Osteopontin inhibits induction of nitric oxide synthase gene expression by inflammatory mediators in mouse kidney epithelial cells
    • Hwang SM, Lopez CA, Heck DE, Gardner CR, Laskin DL, Laskin JD, and Denhardt DT. Osteopontin inhibits induction of nitric oxide synthase gene expression by inflammatory mediators in mouse kidney epithelial cells. J Biol Chem 269: 711-715, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 711-715
    • Hwang, S.M.1    Lopez, C.A.2    Heck, D.E.3    Gardner, C.R.4    Laskin, D.L.5    Laskin, J.D.6    Denhardt, D.T.7
  • 89
    • 0028706978 scopus 로고
    • An evaluation of renal tubular DNA laddering in response to oxygen deprivation and oxidant injury
    • Iwata M, Myerson D, Torok-Storb B, and Zager RA. An evaluation of renal tubular DNA laddering in response to oxygen deprivation and oxidant injury. J Am Soc Nephrol 5: 1307-1313, 1994.
    • (1994) J Am Soc Nephrol , vol.5 , pp. 1307-1313
    • Iwata, M.1    Myerson, D.2    Torok-Storb, B.3    Zager, R.A.4
  • 91
    • 0034879042 scopus 로고    scopus 로고
    • α-MSH decreases apoptosis in ischaemic acute renal failure in rats: Possible mechanism of this beneficial effect
    • Jo SK, Yun SY, Chang KH, Cha DR, Cho WY, Kim HK, and Won NH. α-MSH decreases apoptosis in ischaemic acute renal failure in rats: possible mechanism of this beneficial effect. Nephrol Dial Transplant 16: 1583-1591, 2001.
    • (2001) Nephrol Dial Transplant , vol.16 , pp. 1583-1591
    • Jo, S.K.1    Yun, S.Y.2    Chang, K.H.3    Cha, D.R.4    Cho, W.Y.5    Kim, H.K.6    Won, N.H.7
  • 92
    • 0036498865 scopus 로고    scopus 로고
    • Genetic analysis of the mammalian cell death machinery
    • Joza N, Kroemer G, and Penninger JM. Genetic analysis of the mammalian cell death machinery. Trends Genet 18: 142-149, 2002.
    • (2002) Trends Genet , vol.18 , pp. 142-149
    • Joza, N.1    Kroemer, G.2    Penninger, J.M.3
  • 94
    • 0035575679 scopus 로고    scopus 로고
    • Programmed cell death: Alive and well in the new millennium
    • Kaufmann SH and Hengartner MO. Programmed cell death: alive and well in the new millennium. Trends Cell Biol 11: 526-534, 2001.
    • (2001) Trends Cell Biol , vol.11 , pp. 526-534
    • Kaufmann, S.H.1    Hengartner, M.O.2
  • 95
    • 0031919843 scopus 로고    scopus 로고
    • Identification of gene family of caspases in rat kidney and altered expression in ischemia-reperfusion injury
    • Kaushal GP, Singh AB, and Shah SV. Identification of gene family of caspases in rat kidney and altered expression in ischemia-reperfusion injury. Am J Physiol Renal Physiol 274: F587-F595, 1998.
    • (1998) Am J Physiol Renal Physiol , vol.274
    • Kaushal, G.P.1    Singh, A.B.2    Shah, S.V.3
  • 96
    • 0030798072 scopus 로고    scopus 로고
    • Role of caspases (ICE/ CED 3 proteases) in DNA damage and cell death in response to a mitochondrial inhibitor, antimycin A
    • Kaushal GP, Ueda N, and Shah SV. Role of caspases (ICE/ CED 3 proteases) in DNA damage and cell death in response to a mitochondrial inhibitor, antimycin A. Kidney Int 52: 438-445, 1997.
    • (1997) Kidney Int , vol.52 , pp. 438-445
    • Kaushal, G.P.1    Ueda, N.2    Shah, S.V.3
  • 98
    • 0035180186 scopus 로고    scopus 로고
    • Guanosine supplementation reduces apoptosis and protects renal function in the setting of ischemic injury
    • Kelly K, Plotkin Z, and Dagher P. Guanosine supplementation reduces apoptosis and protects renal function in the setting of ischemic injury. J Clin Invest 108: 1291-1298, 2001.
    • (2001) J Clin Invest , vol.108 , pp. 1291-1298
    • Kelly, K.1    Plotkin, Z.2    Dagher, P.3
  • 99
    • 0015117787 scopus 로고
    • Shrinkage necrosis: A distinct mode of cellular death
    • Kerr JF. Shrinkage necrosis: a distinct mode of cellular death. J Pathol 105: 13-20, 1971.
    • (1971) J Pathol , vol.105 , pp. 13-20
    • Kerr, J.F.1
  • 101
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JF, Wyllie AH, and Currie AR. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26: 239-257, 1972.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 102
    • 0032830209 scopus 로고    scopus 로고
    • Hypoxia induces renal tubular epithelial cell apoptosis in chronic renal disease
    • Khan S, Cleveland RP, Koch CJ, and Schelling JR. Hypoxia induces renal tubular epithelial cell apoptosis in chronic renal disease. Lab Invest 79: 1089-1099, 1999.
    • (1999) Lab Invest , vol.79 , pp. 1089-1099
    • Khan, S.1    Cleveland, R.P.2    Koch, C.J.3    Schelling, J.R.4
  • 105
    • 0029825678 scopus 로고    scopus 로고
    • Oxidized glutathione mediates cation channel activation in calf vascular endothelial cells during oxidant stress
    • Koliwad SK, Elliott SJ, and Kunze DL. Oxidized glutathione mediates cation channel activation in calf vascular endothelial cells during oxidant stress. J Physiol 495: 37-49, 1996.
    • (1996) J Physiol , vol.495 , pp. 37-49
    • Koliwad, S.K.1    Elliott, S.J.2    Kunze, D.L.3
  • 106
    • 0028956550 scopus 로고
    • Regulators of cell death
    • Korsmeyer SJ. Regulators of cell death. Trends Genet 11: 101-105, 1995.
    • (1995) Trends Genet , vol.11 , pp. 101-105
    • Korsmeyer, S.J.1
  • 107
    • 0032991434 scopus 로고    scopus 로고
    • Renal ischemia/reperfusion leads to macrophagemediated increase in pulmonary vascular permeability
    • Kramer AA, Postler G, Salhab KF, Mendez C, Carey LC, and Rabb H. Renal ischemia/reperfusion leads to macrophagemediated increase in pulmonary vascular permeability. Kidney Int 55: 2362-2367, 1999.
    • (1999) Kidney Int , vol.55 , pp. 2362-2367
    • Kramer, A.A.1    Postler, G.2    Salhab, K.F.3    Mendez, C.4    Carey, L.C.5    Rabb, H.6
  • 108
    • 0031918742 scopus 로고    scopus 로고
    • The mitochondrial death/life regulator in apoptosis and necrosis
    • Kroemer G, Dallaporta B, and Resche-Rigon M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu Rev Physiol 60: 619-642, 1998.
    • (1998) Annu Rev Physiol , vol.60 , pp. 619-642
    • Kroemer, G.1    Dallaporta, B.2    Resche-Rigon, M.3
  • 109
    • 0034068601 scopus 로고    scopus 로고
    • Mitochondrial control of cell death
    • Kroemer G and Reed JC. Mitochondrial control of cell death. Nat Med 6: 513-519, 2000.
    • (2000) Nat Med , vol.6 , pp. 513-519
    • Kroemer, G.1    Reed, J.C.2
  • 110
    • 0036633664 scopus 로고    scopus 로고
    • Regulation of JNK/ERK activation, cell apoptosis, and tissue regeneration by monoamine oxidases after renal ischemia-reperfusion
    • Kunduzova OR, Bianchi P, Pizzinat N, Escourrou G, Seguelas MH, Parini A, and Cambon C. Regulation of JNK/ ERK activation, cell apoptosis, and tissue regeneration by monoamine oxidases after renal ischemia-reperfusion. FASEB J 16: 1129-1131, 2002.
    • (2002) FASEB J , vol.16 , pp. 1129-1131
    • Kunduzova, O.R.1    Bianchi, P.2    Pizzinat, N.3    Escourrou, G.4    Seguelas, M.H.5    Parini, A.6    Cambon, C.7
  • 111
    • 0036080574 scopus 로고    scopus 로고
    • Ischemia induces alterations in actin filaments in renal vascular smooth muscle cells
    • Kwon O, Phillips CL, and Molitoris BA. Ischemia induces alterations in actin filaments in renal vascular smooth muscle cells. Am J Physiol Renal Physiol 282: F1012-F1019, 2002.
    • (2002) Am J Physiol Renal Physiol , vol.282
    • Kwon, O.1    Phillips, C.L.2    Molitoris, B.A.3
  • 112
    • 0015142917 scopus 로고
    • Observations on cell volume, ultrastructure, mitochondrial conformation and vital-dye uptake in Ehrlich ascites tumor cells. Effects of inhibiting energy production and function of the plasma membrane
    • Laiho KU, Shelburne JD, and Trump BF. Observations on cell volume, ultrastructure, mitochondrial conformation and vital-dye uptake in Ehrlich ascites tumor cells. Effects of inhibiting energy production and function of the plasma membrane. Am J Pathol 65: 203-230, 1971.
    • (1971) Am J Pathol , vol.65 , pp. 203-230
    • Laiho, K.U.1    Shelburne, J.D.2    Trump, B.F.3
  • 113
    • 0030903968 scopus 로고    scopus 로고
    • The effect of 3-aminobenzamide, an inhibitor of poly-ADP-ribose polymerase, on ischemia/reperfusion damage in rat retina
    • Lam TT. The effect of 3-aminobenzamide, an inhibitor of poly-ADP-ribose polymerase, on ischemia/reperfusion damage in rat retina. Res Commun Mol Pathol Pharmacol 95: 241-252, 1997.
    • (1997) Res Commun Mol Pathol Pharmacol , vol.95 , pp. 241-252
    • Lam, T.T.1
  • 114
    • 0037162833 scopus 로고    scopus 로고
    • Requirement for caspase-2 in stress-induced apoptosis before mitochondrial per-meabilization
    • Lassus P, Opitz-Araya X, and Lazebnik Y. Requirement for caspase-2 in stress-induced apoptosis before mitochondrial per-meabilization. Science 297: 1352-1354, 2002.
    • (2002) Science , vol.297 , pp. 1352-1354
    • Lassus, P.1    Opitz-Araya, X.2    Lazebnik, Y.3
  • 115
    • 0035145895 scopus 로고    scopus 로고
    • i/o proteins are involved in adenosine- and ischemic preconditioning-mediated renal protection
    • i/o proteins are involved in adenosine- and ischemic preconditioning-mediated renal protection. J Am Soc Nephrol 12: 233-240, 2001.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 233-240
    • Lee, H.T.1    Emala, C.W.2
  • 116
    • 0035433420 scopus 로고    scopus 로고
    • Four deaths and a funeral: From caspases to alternative mechanisms
    • Leist M and Jaattela M. Four deaths and a funeral: from caspases to alternative mechanisms. Nat Rev Mol Cell Biol 2: 589-598, 2001.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 589-598
    • Leist, M.1    Jaattela, M.2
  • 118
    • 0032897568 scopus 로고    scopus 로고
    • Necrapoptosis and the mitochondrial permeability transition: Shared pathways to necrosis and apoptosis
    • Lemasters JJV. Necrapoptosis and the mitochondrial permeability transition: shared pathways to necrosis and apoptosis. Am J Physiol Gastrointest Liver Physiol 276: G1-G6, 1999.
    • (1999) Am J Physiol Gastrointest Liver Physiol , vol.276
    • Lemasters, J.J.V.1
  • 120
    • 0031727820 scopus 로고    scopus 로고
    • Sodium ion/hydrogen ion exchange inhibition: A new pharmacologic approach to myocardial ischemia and reperfusion injury
    • Levitsky J, Gurell D, and Frishman WH. Sodium ion/hydrogen ion exchange inhibition: a new pharmacologic approach to myocardial ischemia and reperfusion injury. J Clin Pharmacol 38: 887-897, 1998.
    • (1998) J Clin Pharmacol , vol.38 , pp. 887-897
    • Levitsky, J.1    Gurell, D.2    Frishman, W.H.3
  • 122
    • 0031730108 scopus 로고    scopus 로고
    • Prolonged depletion of guanosine triphosphate induces death of insulin-secreting cells by apoptosis
    • Li G, Segu VB, Rabaglia ME, Luo RH, Kowluru A, and Metz SA. Prolonged depletion of guanosine triphosphate induces death of insulin-secreting cells by apoptosis. Endocrinology 139: 3752-3762, 1998.
    • (1998) Endocrinology , vol.139 , pp. 3752-3762
    • Li, G.1    Segu, V.B.2    Rabaglia, M.E.3    Luo, R.H.4    Kowluru, A.5    Metz, S.A.6
  • 123
    • 0035811496 scopus 로고    scopus 로고
    • Endonuclease G is an apoptotic DNase when released from mitochondria
    • Li LY, Luo X, and Wang X. Endonuclease G is an apoptotic DNase when released from mitochondria. Nature 412: 95-99, 2001.
    • (2001) Nature , vol.412 , pp. 95-99
    • Li, L.Y.1    Luo, X.2    Wang, X.3
  • 125
    • 0031838272 scopus 로고    scopus 로고
    • Biology of ischemic and toxic renal tubular cell injury: Role of nitric oxide and the inflammatory response
    • Lieberthal W. Biology of ischemic and toxic renal tubular cell injury: role of nitric oxide and the inflammatory response. Curr Opin Nephrol Hypertens 7: 289-295, 1998.
    • (1998) Curr Opin Nephrol Hypertens , vol.7 , pp. 289-295
    • Lieberthal, W.1
  • 126
    • 0031657367 scopus 로고    scopus 로고
    • Necrosis and apoptosis in acute renal failure
    • Lieberthal W, Koh J, and Levine J. Necrosis and apoptosis in acute renal failure. Semin Nephrol 18: 505-518, 1998.
    • (1998) Semin Nephrol , vol.18 , pp. 505-518
    • Lieberthal, W.1    Koh, J.2    Levine, J.3
  • 127
    • 0029821680 scopus 로고    scopus 로고
    • Mechanisms of apoptosis and its potential role in renal tubular epithelial cell injury
    • Lieberthal W and Levine JS. Mechanisms of apoptosis and its potential role in renal tubular epithelial cell injury. Am J Physiol Renal Fluid Electrolyte Physiol 271: F477-F488, 1996.
    • (1996) Am J Physiol Renal Fluid Electrolyte Physiol , vol.271
    • Lieberthal, W.1    Levine, J.S.2
  • 128
    • 0031989121 scopus 로고    scopus 로고
    • Graded ATP depletion can cause necrosis or apoptosis of cultured mouse proximal tubular cells
    • Lieberthal W, Menza SA, and Levine JS. Graded ATP depletion can cause necrosis or apoptosis of cultured mouse proximal tubular cells. Am J Physiol Renal Physiol 274: F315-F327, 1998.
    • (1998) Am J Physiol Renal Physiol , vol.274
    • Lieberthal, W.1    Menza, S.A.2    Levine, J.S.3
  • 129
    • 0031761122 scopus 로고    scopus 로고
    • Acute renal failure. I. Relative importance of proximal vs. distal tubular injury
    • Lieberthal W and Nigam SK. Acute renal failure. I. Relative importance of proximal vs. distal tubular injury. Am J Physiol Renal Physiol 275: F623-F631, 1998.
    • (1998) Am J Physiol Renal Physiol , vol.275
    • Lieberthal, W.1    Nigam, S.K.2
  • 131
    • 0030916417 scopus 로고    scopus 로고
    • DFF a heterodimeric protein that functions downstream of caspase- 3 to trigger DNA fragmentation during apoptosis
    • Liu X, Zou H, Slaughter C, and Wang X. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 89: 175-184, 1997.
    • (1997) Cell , vol.89 , pp. 175-184
    • Liu, X.1    Zou, H.2    Slaughter, C.3    Wang, X.4
  • 132
    • 0032911053 scopus 로고    scopus 로고
    • Up-regulation of hepatocyte growth factor receptor: An amplification and targeting mechanism for hepatocyte growth factor action in acute renal failure
    • Liu Y, Tolbert EM, Lin L, Thursby MA, Sun AM, Nakamura T, and Dworkin LD. Up-regulation of hepatocyte growth factor receptor: an amplification and targeting mechanism for hepatocyte growth factor action in acute renal failure. Kidney Int 55: 442-453, 1999.
    • (1999) Kidney Int , vol.55 , pp. 442-453
    • Liu, Y.1    Tolbert, E.M.2    Lin, L.3    Thursby, M.A.4    Sun, A.M.5    Nakamura, T.6    Dworkin, L.D.7
  • 133
    • 0031946532 scopus 로고    scopus 로고
    • Inhibition of poly(ADP-ribose) polymerase: Reduction of ischemic injury and attenuation of N-methyl-D-aspartate-induced neurotransmitter dysregulation
    • Lo EH, Bosque-Hamilton P, and Meng W. Inhibition of poly(ADP-ribose) polymerase: reduction of ischemic injury and attenuation of N-methyl-D-aspartate-induced neurotransmitter dysregulation. Stroke 29: 830-836, 1998.
    • (1998) Stroke , vol.29 , pp. 830-836
    • Lo, E.H.1    Bosque-Hamilton, P.2    Meng, W.3
  • 134
    • 0034630187 scopus 로고    scopus 로고
    • The mitochondrion in cell death control: Certainties and incognita
    • Loeffler M and Kroemer G. The mitochondrion in cell death control: certainties and incognita. Exp Cell Res 256: 19-26, 2000.
    • (2000) Exp Cell Res , vol.256 , pp. 19-26
    • Loeffler, M.1    Kroemer, G.2
  • 135
    • 0033010612 scopus 로고    scopus 로고
    • Apoptosis inducing factor (AIF): A phylogenetically old, caspase-independent effector of cell death
    • Lorenzo HK, Susin SA, Penninger J, and Kroemer G. Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death. Cell Death Differ 6: 516-524, 1999.
    • (1999) Cell Death Differ , vol.6 , pp. 516-524
    • Lorenzo, H.K.1    Susin, S.A.2    Penninger, J.3    Kroemer, G.4
  • 136
    • 0036196425 scopus 로고    scopus 로고
    • Activation and caspase-mediated inhibition of PARP: A molecular switch between fibroblast necrosis and apoptosis in death receptor signaling
    • Los M, Mozoluk M, Ferrari D, Stepczynska A, Stroh C, Renz A, Herceg Z, Wang ZQ, and Schulze-Osthoff K. Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling. Mol Biol Cell 13: 978-988, 2002.
    • (2002) Mol Biol Cell , vol.13 , pp. 978-988
    • Los, M.1    Mozoluk, M.2    Ferrari, D.3    Stepczynska, A.4    Stroh, C.5    Renz, A.6    Herceg, Z.7    Wang, Z.Q.8    Schulze-Osthoff, K.9
  • 137
    • 0034662989 scopus 로고    scopus 로고
    • Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis
    • Maeno E, Ishizaki Y, Kanaseki T, Hazama A, and Okada Y. Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis. Proc Natl Acad Sci USA 97: 9487-9492, 2000.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 9487-9492
    • Maeno, E.1    Ishizaki, Y.2    Kanaseki, T.3    Hazama, A.4    Okada, Y.5
  • 138
    • 0028891783 scopus 로고
    • Apoptosis, oncosis, and necrosis. An overview of cell death
    • Majno G and Joris I. Apoptosis, oncosis, and necrosis. An overview of cell death. Am J Pathol 146: 3-15, 1995.
    • (1995) Am J Pathol , vol.146 , pp. 3-15
    • Majno, G.1    Joris, I.2
  • 139
    • 0033020019 scopus 로고    scopus 로고
    • Staining apoptosis in paraffin sections. Advantages and limits
    • Mangili F, Cigala C, and Santambrogio G. Staining apoptosis in paraffin sections. Advantages and limits. Anal Quant Cytol Histol 21: 273-276, 1999.
    • (1999) Anal Quant Cytol Histol , vol.21 , pp. 273-276
    • Mangili, F.1    Cigala, C.2    Santambrogio, G.3
  • 141
    • 0035348408 scopus 로고    scopus 로고
    • Neuronal cell death in nervous system development, disease, and injury
    • Martin LJ. Neuronal cell death in nervous system development, disease, and injury. Int J Mol Med 7: 455-478, 2001.
    • (2001) Int J Mol Med , vol.7 , pp. 455-478
    • Martin, L.J.1
  • 142
    • 0018399219 scopus 로고
    • The early phase of experimental acute renal failure. IV. The diluting ability of the short loops of Henle
    • Mason J, Gutsche HU, Moore L, and Muller-Suur R. The early phase of experimental acute renal failure. IV. The diluting ability of the short loops of Henle. Pflügers Arch 379: 11-18, 1979.
    • (1979) Pflügers Arch , vol.379 , pp. 11-18
    • Mason, J.1    Gutsche, H.U.2    Moore, L.3    Muller-Suur, R.4
  • 144
    • 0021227520 scopus 로고
    • Lipid alterations induced by renal ischemia: Pathogenic factor in membrane damage
    • Matthys E, Patel Y, Kreisberg J, Stewart JH, and Venkatachalam M. Lipid alterations induced by renal ischemia: pathogenic factor in membrane damage. Kidney Int 26: 153-161, 1984.
    • (1984) Kidney Int , vol.26 , pp. 153-161
    • Matthys, E.1    Patel, Y.2    Kreisberg, J.3    Stewart, J.H.4    Venkatachalam, M.5
  • 145
    • 0036285014 scopus 로고    scopus 로고
    • Simulated ischemia induces renal tubular cell apoptosis through a nuclear factor-kappaB dependent mechanism
    • Meldrum KK, Hile K, Meldrum DR, Crone JA, Gearhart JP, and Burnett AL. Simulated ischemia induces renal tubular cell apoptosis through a nuclear factor-kappaB dependent mechanism. J Urol 168: 248-252, 2002.
    • (2002) J Urol , vol.168 , pp. 248-252
    • Meldrum, K.K.1    Hile, K.2    Meldrum, D.R.3    Crone, J.A.4    Gearhart, J.P.5    Burnett, A.L.6
  • 154
    • 0025827433 scopus 로고
    • Ischemia-induced loss of epithelial polarity: Potential role of the actin cytoskeleton
    • Molitoris BA. Ischemia-induced loss of epithelial polarity: potential role of the actin cytoskeleton. Am J Physiol Renal Fluid Electrolyte Physiol 260: F769-F778, 1991.
    • (1991) Am J Physiol Renal Fluid Electrolyte Physiol , vol.260
    • Molitoris, B.A.1
  • 155
    • 0027137547 scopus 로고
    • +-ATPase that redistributes to apical membrane during ATP depletion remains functional
    • +-ATPase that redistributes to apical membrane during ATP depletion remains functional. Am J Physiol Renal Fluid Electrolyte Physiol 265: F693-F697, 1993.
    • (1993) Am J Physiol Renal Fluid Electrolyte Physiol , vol.265
    • Molitoris, B.A.1
  • 156
    • 33751318939 scopus 로고    scopus 로고
    • Putting the actin cytoskeleton into perspective: Pathophysiology of ischemic alterations
    • Molitoris BA. Putting the actin cytoskeleton into perspective: pathophysiology of ischemic alterations. Aro Am J Physiol Renal Physiol 272: F430-F433, 1997.
    • (1997) Aro Am J Physiol Renal Physiol , vol.272
    • Molitoris, B.A.1
  • 157
    • 0025861527 scopus 로고
    • +-ATPase from its surface membrane actin cytoskeletal complex during cellular ATP depletion
    • +-ATPase from its surface membrane actin cytoskeletal complex during cellular ATP depletion. J Clin Invest 88: 462-469, 1991.
    • (1991) J Clin Invest , vol.88 , pp. 462-469
    • Molitoris, B.A.1    Geerdes, A.2    McIntosh, J.R.3
  • 158
    • 0036245205 scopus 로고    scopus 로고
    • Endothelial injury and dysfunction in ischemic acute renal failure
    • Molitoris BA, Sandoval R, and Sutton TA. Endothelial injury and dysfunction in ischemic acute renal failure. Crit Care Med 30: S235-S240, 2002.
    • (2002) Crit Care Med , vol.30
    • Molitoris, B.A.1    Sandoval, R.2    Sutton, T.A.3
  • 161
    • 0034630317 scopus 로고    scopus 로고
    • Apoptotic DNA fragmentation
    • Nagata S. Apoptotic DNA fragmentation. Exp Cell Res 256: 12-18, 2000.
    • (2000) Exp Cell Res , vol.256 , pp. 12-18
    • Nagata, S.1
  • 162
    • 0035265686 scopus 로고    scopus 로고
    • PUMA a novel proapoptotic gene, is induced by p 53
    • Nakano K and Vousden KH. PUMA, a novel proapoptotic gene, is induced by p53. Mol Cell 7: 683-694, 2001.
    • (2001) Mol Cell , vol.7 , pp. 683-694
    • Nakano, K.1    Vousden, K.H.2
  • 163
    • 0034641932 scopus 로고    scopus 로고
    • From bench to clinic with apoptosis-based therapeutic agents
    • Nicholson DW. From bench to clinic with apoptosis-based therapeutic agents. Nature 407: 810-816, 2000.
    • (2000) Nature , vol.407 , pp. 810-816
    • Nicholson, D.W.1
  • 164
    • 0029610692 scopus 로고
    • Lipid mediators and protein kinase C for intracellular signalling
    • Nishizuka Y and Nakamura S. Lipid mediators and protein kinase C for intracellular signalling. Clin Exp Pharmacol Physiol Suppl 1: S202-S203, 1995.
    • (1995) Clin Exp Pharmacol Physiol Suppl , vol.1
    • Nishizuka, Y.1    Nakamura, S.2
  • 167
    • 0029929229 scopus 로고    scopus 로고
    • In vivo targeting of inducible NO synthase with oligodeoxynucleotides protects rat kidney against ischemia
    • Noiri E, Peresleni T, Miller F, and Goligorsky MS. In vivo targeting of inducible NO synthase with oligodeoxynucleotides protects rat kidney against ischemia. J Clin Invest 97: 2377-2383, 1996.
    • (1996) J Clin Invest , vol.97 , pp. 2377-2383
    • Noiri, E.1    Peresleni, T.2    Miller, F.3    Goligorsky, M.S.4
  • 168
    • 0033230611 scopus 로고    scopus 로고
    • Apoptotic cytosol facilitates Bax translocation to mitochondria that involves cytosolic factor regulated by Bcl- 2
    • Nomura M, Shimizu S, Ito T, Narita M, Matsuda H, and Tsujimoto Y. Apoptotic cytosol facilitates Bax translocation to mitochondria that involves cytosolic factor regulated by Bcl-2. Cancer Res 59: 5542-5548, 1999.
    • (1999) Cancer Res , vol.59 , pp. 5542-5548
    • Nomura, M.1    Shimizu, S.2    Ito, T.3    Narita, M.4    Matsuda, H.5    Tsujimoto, Y.6
  • 169
    • 0035310427 scopus 로고    scopus 로고
    • Receptor-mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD)
    • Okada Y, Maeno E, Shimizu T, Dezaki K, Wang J, and Morishima S. Receptor-mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD), J Physiol 532: 3-16, 2001.
    • (2001) J Physiol , vol.532 , pp. 3-16
    • Okada, Y.1    Maeno, E.2    Shimizu, T.3    Dezaki, K.4    Wang, J.5    Morishima, S.6
  • 170
    • 0036288269 scopus 로고    scopus 로고
    • The inflammatory cascade in acute ischemic renal failure
    • Okusa MD. The inflammatory cascade in acute ischemic renal failure. Nephron 90: 133-138, 2002.
    • (2002) Nephron , vol.90 , pp. 133-138
    • Okusa, M.D.1
  • 172
    • 0032787793 scopus 로고    scopus 로고
    • The Fas ligand/Fas system in renal injury
    • Ortiz A, Lorz C, and Egido J. The Fas ligand/Fas system in renal injury. Nephrol Dial Transplant 14: 1831-1834, 1999.
    • (1999) Nephrol Dial Transplant , vol.14 , pp. 1831-1834
    • Ortiz, A.1    Lorz, C.2    Egido, J.3
  • 173
    • 0035046166 scopus 로고    scopus 로고
    • Induction and subcellular localization of protein kinase C isozymes following renal ischemia
    • Padanilam BJ. Induction and subcellular localization of protein kinase C isozymes following renal ischemia. Kidney Int 59: 1789-1797, 2001.
    • (2001) Kidney Int , vol.59 , pp. 1789-1797
    • Padanilam, B.J.1
  • 174
    • 0030772365 scopus 로고    scopus 로고
    • Ischemia-induced receptor for activated C kinase (RACK1) expression in rat kidneys
    • Padanilam BJ and Hammerman MR. Ischemia-induced receptor for activated C kinase (RACK1) expression in rat kidneys. Am J Physiol Renal Physiol 272: F160-F166, 1997.
    • (1997) Am J Physiol Renal Physiol , vol.272
    • Padanilam, B.J.1    Hammerman, M.R.2
  • 175
    • 0032956878 scopus 로고    scopus 로고
    • Molecular mechanisms of cell death and regeneration in acute ischemic renal injury
    • Padanilam BJ and Lewington AJ. Molecular mechanisms of cell death and regeneration in acute ischemic renal injury. Curr Opin Nephrol Hypertens 8: 15-19, 1999.
    • (1999) Curr Opin Nephrol Hypertens , vol.8 , pp. 15-19
    • Padanilam, B.J.1    Lewington, A.J.2
  • 176
    • 0031756662 scopus 로고    scopus 로고
    • Expression of CD27 and ischemia/reperfusion-induced expression of its ligand Siva in rat kidneys
    • Padanilam BJ, Lewington AJ, and Hammerman MR. Expression of CD27 and ischemia/reperfusion-induced expression of its ligand Siva in rat kidneys. Kidney Int 54: 1967-1975, 1998.
    • (1998) Kidney Int , vol.54 , pp. 1967-1975
    • Padanilam, B.J.1    Lewington, A.J.2    Hammerman, M.R.3
  • 177
    • 0029914839 scopus 로고    scopus 로고
    • Insulinlike growth factor 1-enhanced renal expression of osteopontin after acute ischemic injury in rats
    • Padanilam BJ, Martin DR, and Hammerman MR. Insulinlike growth factor 1-enhanced renal expression of osteopontin after acute ischemic injury in rats. Endocrinology 137: 2133-2140, 1996.
    • (1996) Endocrinology , vol.137 , pp. 2133-2140
    • Padanilam, B.J.1    Martin, D.R.2    Hammerman, M.R.3
  • 178
    • 0037127298 scopus 로고    scopus 로고
    • Prevention of kidney ischemia/reperfusion-induced functional injury, MAPK and MAPK kinase activation, and inflammation by remote transient ureteral obstruction
    • Park KM, Kramers C, Vayssier-Taussat M, Chen A, and Bonventre JV. Prevention of kidney ischemia/reperfusion-induced functional injury, MAPK and MAPK kinase activation, and inflammation by remote transient ureteral obstruction. J Biol Chem 277: 2040-2049, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 2040-2049
    • Park, K.M.1    Kramers, C.2    Vayssier-Taussat, M.3    Chen, A.4    Bonventre, J.V.5
  • 180
    • 0035811511 scopus 로고    scopus 로고
    • Mitochondrial endonuclease G is important for apoptosis in C. elegans
    • Parrish J, Li L, Klotz K, Ledwich D, Wang X, and Xue D. Mitochondrial endonuclease G is important for apoptosis in C. elegans. Nature 412: 90-94, 2001.
    • (2001) Nature , vol.412 , pp. 90-94
    • Parrish, J.1    Li, L.2    Klotz, K.3    Ledwich, D.4    Wang, X.5    Xue, D.6
  • 181
  • 185
    • 0033458684 scopus 로고    scopus 로고
    • Role of fatty acid beta-oxidation and calciumindependent phospholipase A2 in ischemie acute renal failure
    • Portilla D. Role of fatty acid beta-oxidation and calciumindependent phospholipase A2 in ischemie acute renal failure, Curr Opin Nephrol Hypertens 8: 473-477, 1999.
    • (1999) Curr Opin Nephrol Hypertens , vol.8 , pp. 473-477
    • Portilla, D.1
  • 186
    • 0028296219 scopus 로고
    • Role of cytosolic calcium-independent plasmalogen-selective phospholipase A 2 in hypoxic injury to rabbit proximal tubules
    • Portilla D, Shah SV, Lehman PA, and Creer MH. Role of cytosolic calcium-independent plasmalogen-selective phospholipase A2 in hypoxic injury to rabbit proximal tubules. J Clin Invest 93: 1609-1615, 1994.
    • (1994) J Clin Invest , vol.93 , pp. 1609-1615
    • Portilla, D.1    Shah, S.V.2    Lehman, P.A.3    Creer, M.H.4
  • 188
    • 0035071672 scopus 로고    scopus 로고
    • Role of programmed cell death in development
    • Ranganath RM and Nagashree NR. Role of programmed cell death in development. Int Rev Cytol 202: 159-242, 2001.
    • (2001) Int Rev Cytol , vol.202 , pp. 159-242
    • Ranganath, R.M.1    Nagashree, N.R.2
  • 189
    • 0030465544 scopus 로고    scopus 로고
    • Lamin proteolysis facilitates nuclear events during apoptosis
    • Rao L, Perez D, and White E. Lamin proteolysis facilitates nuclear events during apoptosis. J Cell Biol 135: 1441-1455, 1996.
    • (1996) J Cell Biol , vol.135 , pp. 1441-1455
    • Rao, L.1    Perez, D.2    White, E.3
  • 191
    • 17744376764 scopus 로고    scopus 로고
    • Mechanisms of mitochondrial membrane permeabilization
    • Reed JC and Kroemer G. Mechanisms of mitochondrial membrane permeabilization (Abstract). Cell Death Differ 7: 1145, 2000.
    • (2000) Cell Death Differ , vol.7 , pp. 1145
    • Reed, J.C.1    Kroemer, G.2
  • 192
    • 0034641963 scopus 로고    scopus 로고
    • Defying death after DNA damage
    • Rich T, Allen RL, and Wyllie AH. Defying death after DNA damage. Nature 407: 777-783, 2000.
    • (2000) Nature , vol.407 , pp. 777-783
    • Rich, T.1    Allen, R.L.2    Wyllie, A.H.3
  • 194
    • 0033930833 scopus 로고    scopus 로고
    • Programmed cell-death regulation: Basic mechanisms and therapeutic opportunities
    • American Association for Cancer Research Special Conference: Lake Tahoe, CA., USA, 27 February-2 March 2000
    • Roy S and Nicholson DW. Programmed cell-death regulation: basic mechanisms and therapeutic opportunities. American Association for Cancer Research Special Conference: Lake Tahoe, CA., USA, 27 February-2 March 2000. Mol Med Today 6: 264-266, 2000.
    • (2000) Mol Med Today , vol.6 , pp. 264-266
    • Roy, S.1    Nicholson, D.W.2
  • 195
    • 0030918572 scopus 로고    scopus 로고
    • Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK 2
    • Rudel T and Bokoch GM. Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2. Science 276: 1571-1574, 1997.
    • (1997) Science , vol.276 , pp. 1571-1574
    • Rudel, T.1    Bokoch, G.M.2
  • 196
    • 0032585644 scopus 로고    scopus 로고
    • Role of hypoxia poxia-induced Bax translocation and cytochrome c release in reoxygenation injury
    • Saikumar P, Dong Z, Patel Y, Hall K, Hopfer U, Weinberg JM, and Venkatachalam MA. Role of hypoxia poxia-induced Bax translocation and cytochrome c release in reoxygenation injury. Oncogene 17: 3401-3415, 1998.
    • (1998) Oncogene , vol.17 , pp. 3401-3415
    • Saikumar, P.1    Dong, Z.2    Patel, Y.3    Hall, K.4    Hopfer, U.5    Weinberg, J.M.6    Venkatachalam, M.A.7
  • 197
    • 0032409943 scopus 로고    scopus 로고
    • Mechanisms of cell death in hypoxia/reoxygenation injury
    • Saikumar P, Dong Z, Weinberg JM, and Venkatachalam MA. Mechanisms of cell death in hypoxia/reoxygenation injury. Oncogene 17: 3341-3349, 1998.
    • (1998) Oncogene , vol.17 , pp. 3341-3349
    • Saikumar, P.1    Dong, Z.2    Weinberg, J.M.3    Venkatachalam, M.A.4
  • 198
    • 0035298355 scopus 로고    scopus 로고
    • Enzymatic active site of caspase-activated DNase (CAD) and its inhibition by inhibitor of CAD
    • Sakahira H, Takemura Y, and Nagata S. Enzymatic active site of caspase-activated DNase (CAD) and its inhibition by inhibitor of CAD. Arch Biochem Biophys 388: 91-99, 2001.
    • (2001) Arch Biochem Biophys , vol.388 , pp. 91-99
    • Sakahira, H.1    Takemura, Y.2    Nagata, S.3
  • 199
    • 0014006159 scopus 로고
    • Death in embryonic systems
    • Saunders JW Jr. Death in embryonic systems. Science 154: 604-612, 1966.
    • (1966) Science , vol.154 , pp. 604-612
    • Saunders J.W., Jr.1
  • 200
  • 201
    • 0037062934 scopus 로고    scopus 로고
    • Release of chromatin protein HMGB 1 by necrotic cells triggers inflammation
    • Scaffidi P, Misteli T, and Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 418: 191-195, 2002.
    • (2002) Nature , vol.418 , pp. 191-195
    • Scaffidi, P.1    Misteli, T.2    Bianchi, M.E.3
  • 202
    • 0031659489 scopus 로고    scopus 로고
    • Proteases in renal cell death: Calpains mediate cell death produced by diverse toxicants
    • Schnellmann RG and Williams SW. Proteases in renal cell death: calpains mediate cell death produced by diverse toxicants. Ren Fail 20: 679-686, 1998.
    • (1998) Ren Fail , vol.20 , pp. 679-686
    • Schnellmann, R.G.1    Williams, S.W.2
  • 203
    • 0026713818 scopus 로고
    • Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation
    • Schulze-Osthoff K, Bakker AC, Vanhaesebroeck B, Beyaert R, Jacob WA, and Fiers W. Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation. J Biol Chem 267: 5317-5323, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 5317-5323
    • Schulze-Osthoff, K.1    Bakker, A.C.2    Vanhaesebroeck, B.3    Beyaert, R.4    Jacob, W.A.5    Fiers, W.6
  • 205
    • 0034645740 scopus 로고    scopus 로고
    • Pathophysiology of acute renal failure at the cellular level
    • Schwarz C, Gruber U, and Oberbauer R. Pathophysiology of acute renal failure at the cellular level. Wien Klin Wochenschr 112: 5-15, 2000.
    • (2000) Wien Klin Wochenschr , vol.112 , pp. 5-15
    • Schwarz, C.1    Gruber, U.2    Oberbauer, R.3
  • 206
    • 0035532658 scopus 로고    scopus 로고
    • Pathophysiology of ischemic acute renal failure
    • Sheridan AM and Bonventre JV. Pathophysiology of ischemic acute renal failure. Contrib Nephrol 132: 7-21, 2001.
    • (2001) Contrib Nephrol , vol.132 , pp. 7-21
    • Sheridan, A.M.1    Bonventre, J.V.2
  • 207
    • 0036163042 scopus 로고    scopus 로고
    • A conserved tetrapeptide motif: Potentiating apoptosis through IAP-binding
    • Shi Y. A conserved tetrapeptide motif: potentiating apoptosis through IAP-binding. Cell Death Differ 9: 93-95, 2002.
    • (2002) Cell Death Differ , vol.9 , pp. 93-95
    • Shi, Y.1
  • 208
    • 0033826589 scopus 로고    scopus 로고
    • Downregulation of the calpain inhibitor protein calpastatin by caspases during renal ischemia-reperfusion
    • Shi Y, Melnikov V, Schrier R, and Edelstein C. Downregulation of the calpain inhibitor protein calpastatin by caspases during renal ischemia-reperfusion. Am J Physiol Renal Physiol 279: F509-F517, 2000.
    • (2000) Am J Physiol Renal Physiol , vol.279
    • Shi, Y.1    Melnikov, V.2    Schrier, R.3    Edelstein, C.4
  • 209
    • 0033519705 scopus 로고    scopus 로고
    • Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
    • Shimizu S, Narita M, and Tsujimoto Y. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature 399: 483-487, 1999.
    • (1999) Nature , vol.399 , pp. 483-487
    • Shimizu, S.1    Narita, M.2    Tsujimoto, Y.3
  • 210
    • 0036189914 scopus 로고    scopus 로고
    • Markers of apoptosis: Methods for elucidating the mechanism of apoptotic cell death from the nervous system
    • Smyth PG and Berman SA. Markers of apoptosis: methods for elucidating the mechanism of apoptotic cell death from the nervous system. Biotechniques 32: 648-654, 2002.
    • (2002) Biotechniques , vol.32 , pp. 648-654
    • Smyth, P.G.1    Berman, S.A.2
  • 211
    • 0035969239 scopus 로고    scopus 로고
    • Tethering and tickling: A new role for the phosphatidylserine receptor
    • Somersan S and Bhardwaj N. Tethering and tickling: a new role for the phosphatidylserine receptor. J Cell Biol 155: 501-504, 2001.
    • (2001) J Cell Biol , vol.155 , pp. 501-504
    • Somersan, S.1    Bhardwaj, N.2
  • 217
    • 0033713002 scopus 로고    scopus 로고
    • Structure of Bax: Coregulation of dimer formation and intracellular localization
    • Suzuki M, Youle RJ, and Tjandra N. Structure of Bax: coregulation of dimer formation and intracellular localization. Cell 103: 645-654, 2000.
    • (2000) Cell , vol.103 , pp. 645-654
    • Suzuki, M.1    Youle, R.J.2    Tjandra, N.3
  • 218
    • 0030975020 scopus 로고    scopus 로고
    • The cytokine-adhesion molecule cascade in ischemia/reperfusion injury of the rat kidney. Inhibition by a soluble P-selectin ligand
    • Takada M, Nadeau KC, Shaw GD, Marquette KA, and Tilney NL. The cytokine-adhesion molecule cascade in ischemia/reperfusion injury of the rat kidney. Inhibition by a soluble P-selectin ligand. J Clin Invest 99: 2682-2690, 1997.
    • (1997) J Clin Invest , vol.99 , pp. 2682-2690
    • Takada, M.1    Nadeau, K.C.2    Shaw, G.D.3    Marquette, K.A.4    Tilney, N.L.5
  • 220
    • 0032805106 scopus 로고    scopus 로고
    • Caspases: A decade of death research
    • Thornberry NA. Caspases: a decade of death research. Cell Death Differ 6: 1023-1027, 1999.
    • (1999) Cell Death Differ , vol.6 , pp. 1023-1027
    • Thornberry, N.A.1
  • 221
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry NA and Lazebnik Y. Caspases: enemies within. Science 281: 1312-1316, 1998.
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 222
    • 0031892556 scopus 로고    scopus 로고
    • Effects of insulinlike growth factor I on the renal juxtamedullary microvasculature
    • Tonshoff B, Kaskel FJ, and Moore LC. Effects of insulinlike growth factor I on the renal juxtamedullary microvasculature. Am J Physiol Renal Physiol 274: F120-F128, 1998.
    • (1998) Am J Physiol Renal Physiol , vol.274
    • Tonshoff, B.1    Kaskel, F.J.2    Moore, L.C.3
  • 224
    • 0013813283 scopus 로고
    • Studies of mouse liver necrosis in vitro. Ultrastructural and cytochemical alterations in hepatic parenchymal cell nuclei
    • Trump BF, Goldblatt PJ, and Stowell RE. Studies of mouse liver necrosis in vitro. Ultrastructural and cytochemical alterations in hepatic parenchymal cell nuclei. Lab Invest 14: 1969-1999, 1965.
    • (1965) Lab Invest , vol.14 , pp. 1969-1999
    • Trump, B.F.1    Goldblatt, P.J.2    Stowell, R.E.3
  • 225
    • 0013818771 scopus 로고
    • Studies of necrosis in vitro of mouse hepatic parenchymal cells. Ultrastructural alterations in endoplasmic reticulum, Golgi apparatus, plasma membrane, and lipid droplets
    • Trump BF, Goldblatt PJ, and Stowell RE. Studies of necrosis in vitro of mouse hepatic parenchymal cells. Ultrastructural alterations in endoplasmic reticulum, Golgi apparatus, plasma membrane, and lipid droplets. Lab Invest 14: 2000-2028, 1965.
    • (1965) Lab Invest , vol.14 , pp. 2000-2028
    • Trump, B.F.1    Goldblatt, P.J.2    Stowell, R.E.3
  • 226
    • 0031726359 scopus 로고    scopus 로고
    • Inhibition of fas death signals by FLIPs
    • Tschopp J, Irmler M, and Thome M. Inhibition of fas death signals by FLIPs. Curr Opin Immunol 10: 552-558, 1998.
    • (1998) Curr Opin Immunol , vol.10 , pp. 552-558
    • Tschopp, J.1    Irmler, M.2    Thome, M.3
  • 227
    • 0033971901 scopus 로고    scopus 로고
    • Bcl-2 family: Life-or-death switch
    • Tsujimoto Y and Shimizu S. Bcl-2 family: life-or-death switch. FEBS Lett 466: 6-10, 2000.
    • (2000) FEBS Lett , vol.466 , pp. 6-10
    • Tsujimoto, Y.1    Shimizu, S.2
  • 228
    • 0034525413 scopus 로고    scopus 로고
    • VDAC regulation by the Bcl- 2 family of proteins
    • Tsujimoto Y and Shimizu S. VDAC regulation by the Bcl-2 family of proteins. Cell Death Differ 7: 1174-1181, 2000.
    • (2000) Cell Death Differ , vol.7 , pp. 1174-1181
    • Tsujimoto, Y.1    Shimizu, S.2
  • 229
    • 0033955168 scopus 로고    scopus 로고
    • Role of endonucleases in renal tubular epithelial cell injury
    • Ueda N and Shah S. Role of endonucleases in renal tubular epithelial cell injury. Exp Nephrol 8: 8-13, 2000.
    • (2000) Exp Nephrol , vol.8 , pp. 8-13
    • Ueda, N.1    Shah, S.2
  • 231
    • 0031873922 scopus 로고    scopus 로고
    • Heat shock proteins in renal injury and recovery
    • Van Why SK and Siegel NJ. Heat shock proteins in renal injury and recovery. Curr Opin Nephrol Hypertens 7: 407-412, 1998.
    • (1998) Curr Opin Nephrol Hypertens , vol.7 , pp. 407-412
    • Van Why, S.K.1    Siegel, N.J.2
  • 234
    • 0027958067 scopus 로고
    • Reconstruction of blood flow distribution in the rat kidney during postischemic renal failure
    • Vetterlein F, Bludau J, Petho-Schramm A, and Schmidt G. Reconstruction of blood flow distribution in the rat kidney during postischemic renal failure. Nephron 66: 208-214, 1994.
    • (1994) Nephron , vol.66 , pp. 208-214
    • Vetterlein, F.1    Bludau, J.2    Petho-Schramm, A.3    Schmidt, G.4
  • 235
    • 0023030776 scopus 로고
    • Distribution of capillary blood flow in rat kidney during postischemic renal failure
    • Vetterlein F, Petho A, and Schmidt G. Distribution of capillary blood flow in rat kidney during postischemic renal failure. Am J Physiol Heart Circ Physiol 251: H510-H519, 1986.
    • (1986) Am J Physiol Heart Circ Physiol , vol.251
    • Vetterlein, F.1    Petho, A.2    Schmidt, G.3
  • 236
    • 0034898944 scopus 로고    scopus 로고
    • Hepatocyte growth factor inhibits apoptosis after ischemic renal injury in rats
    • Vijayan A, Martin DR, Sadow JL, Kissane J, and Miller SB. Hepatocyte growth factor inhibits apoptosis after ischemic renal injury in rats. Am J Kidney Dis 38: 274-278, 2001.
    • (2001) Am J Kidney Dis , vol.38 , pp. 274-278
    • Vijayan, A.1    Martin, D.R.2    Sadow, J.L.3    Kissane, J.4    Miller, S.B.5
  • 237
    • 0031749607 scopus 로고    scopus 로고
    • Meprin A, the major matrix degrading enzyme in renal tubules, produces a novel nidogen fragment in vitro and in vivo
    • Walker PD, Kaushal GP, and Shah SV. Meprin A, the major matrix degrading enzyme in renal tubules, produces a novel nidogen fragment in vitro and in vivo. Kidney Int 53: 1673-1680, 1998.
    • (1998) Kidney Int , vol.53 , pp. 1673-1680
    • Walker, P.D.1    Kaushal, G.P.2    Shah, S.V.3
  • 239
    • 0033956278 scopus 로고    scopus 로고
    • Calpain and caspase: Can you tell the difference?
    • Wang KK. Calpain and caspase: can you tell the difference? Trends Neurosci 23: 20-26, 2000.
    • (2000) Trends Neurosci , vol.23 , pp. 20-26
    • Wang, K.K.1
  • 241
    • 0025761170 scopus 로고
    • The cell biology of ischemic renal injury
    • Weinberg JM. The cell biology of ischemic renal injury. Kidney Int 39: 476-500, 1991.
    • (1991) Kidney Int , vol.39 , pp. 476-500
    • Weinberg, J.M.1
  • 242
    • 0034646270 scopus 로고    scopus 로고
    • Mitochondrial dysfunction during hypoxia/reoxygenation and its correction by anaerobic metabolism of citric acid cycle intermediates
    • Weinberg JM, Venkatachalam MA, Roeser NF, and Nissita I. Mitochondrial dysfunction during hypoxia/reoxygenation and its correction by anaerobic metabolism of citric acid cycle intermediates. Proc Natl Acad Sci USA 97: 2826-2831, 2000.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 2826-2831
    • Weinberg, J.M.1    Venkatachalam, M.A.2    Roeser, N.F.3    Nissita, I.4
  • 243
    • 0035153242 scopus 로고    scopus 로고
    • Secondary necrosis is a source of proteolytically modified forms of specific intracellular autoantigens: Implications for systemic autoimmunity
    • Wu X, Molinaro C, Johnson N, and Casiano CA. Secondary necrosis is a source of proteolytically modified forms of specific intracellular autoantigens: implications for systemic autoimmunity. Arthritis Rheum 44: 2642-2652, 2001.
    • (2001) Arthritis Rheum , vol.44 , pp. 2642-2652
    • Wu, X.1    Molinaro, C.2    Johnson, N.3    Casiano, C.A.4
  • 245
    • 0018830636 scopus 로고
    • Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • Wyllie AH. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284: 555-556, 1980.
    • (1980) Nature , vol.284 , pp. 555-556
    • Wyllie, A.H.1
  • 246
    • 0019225636 scopus 로고
    • Cell death: The significance of apoptosis
    • Wyllie AH, Kerr JF, and Currie AR. Cell death: the significance of apoptosis. Int Rev Cytol 68: 251-306, 1980.
    • (1980) Int Rev Cytol , vol.68 , pp. 251-306
    • Wyllie, A.H.1    Kerr, J.F.2    Currie, A.R.3
  • 250
    • 0029661827 scopus 로고    scopus 로고
    • 2-induced cytoprotection of proximal tubules: Potential determinants and specificity for ATP depletion-mediated injury
    • 2-induced cytoprotection of proximal tubules: potential determinants and specificity for ATP depletion-mediated injury. J Am Soc Nephrol 7: 64-72, 1996.
    • (1996) J Am Soc Nephrol , vol.7 , pp. 64-72
    • Zager, R.A.1    Burkhart, K.M.2    Conrad, D.S.3    Gmur, D.J.4    Iwata, M.5
  • 251
    • 0030299860 scopus 로고    scopus 로고
    • Phospholipase A2: A potentially important determinant of adenosine triphosphate levels during hypoxic-reoxygenation tubular injury
    • Zager RA, Conrad DS, and Burkhart K. Phospholipase A2: a potentially important determinant of adenosine triphosphate levels during hypoxic-reoxygenation tubular injury. J Am Soc Nephrol 7: 2327-2339, 1996.
    • (1996) J Am Soc Nephrol , vol.7 , pp. 2327-2339
    • Zager, R.A.1    Conrad, D.S.2    Burkhart, K.3
  • 252
    • 0035229427 scopus 로고    scopus 로고
    • The mitochondrion in apoptosis: How Pandora's box opens
    • Zamzami N and Kroemer G. The mitochondrion in apoptosis: how Pandora's box opens. Nat Rev Mol Cell Biol 2: 67-71, 2001.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 67-71
    • Zamzami, N.1    Kroemer, G.2
  • 253
    • 0028294246 scopus 로고
    • Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity
    • Zhang J, Dawson VL, Dawson TM, and Snyder SH. Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science 263: 687-689, 1994.
    • (1994) Science , vol.263 , pp. 687-689
    • Zhang, J.1    Dawson, V.L.2    Dawson, T.M.3    Snyder, S.H.4
  • 254
    • 0032514713 scopus 로고    scopus 로고
    • Resistance to DNA fragmentation and chromatin condensation in mice lacking the DNA fragmentation factor 45
    • Zhang J, Liu X, Scherer DC, van Kaer L, Wang X, and Xu M. Resistance to DNA fragmentation and chromatin condensation in mice lacking the DNA fragmentation factor 45. Proc Natl Acad Sci USA 95: 12480-12485, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 12480-12485
    • Zhang, J.1    Liu, X.2    Scherer, D.C.3    Van Kaer, L.4    Wang, X.5    Xu, M.6
  • 255
    • 0036469777 scopus 로고    scopus 로고
    • Apoptotic DNA fragmentation and tissue homeostasis
    • Zhang J and Xu M. Apoptotic DNA fragmentation and tissue homeostasis. Trends Cell Biol 12: 84-89, 2002.
    • (2002) Trends Cell Biol , vol.12 , pp. 84-89
    • Zhang, J.1    Xu, M.2
  • 256
    • 0034279897 scopus 로고    scopus 로고
    • DNA fragmentation in apoptosis
    • Zhang JH and Xu M. DNA fragmentation in apoptosis. Cell Res 10: 205-211, 2000.
    • (2000) Cell Res , vol.10 , pp. 205-211
    • Zhang, J.H.1    Xu, M.2
  • 257
    • 0031281259 scopus 로고    scopus 로고
    • Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase
    • Zingarelli B, Cuzzocrea S, Zsengeller Z, Salzman AL, and Szabo C. Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase. Cardiovasc Res 36: 205-215, 1997.
    • (1997) Cardiovasc Res , vol.36 , pp. 205-215
    • Zingarelli, B.1    Cuzzocrea, S.2    Zsengeller, Z.3    Salzman, A.L.4    Szabo, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.