Methods for detecting apoptosis in thyroid diseases

Journal of Immunological Methods

Volumn 265, Issue 1-2, 2002, Pages 161-175

  Mirakian, R ^a   Nye, K ^a   Palazzo, F F ^a   Goode, A W ^a   Hammond, L J ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Apoptosis; Bcl 2; Fas FasL; Thyroid autoimmunity; TRAIL TRAIL R

Indexed keywords

ALKALINE PHOSPHATASE; CASPASE 3; CASPASE 8; CD3 ANTIGEN; CD45 ANTIGEN; DNA NUCLEOTIDYLEXOTRANSFERASE; EDETIC ACID; FAS ANTIBODY; FAS LIGAND; GAMMA INTERFERON; IMMUNOGLOBULIN M ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 4; LIPOCORTIN 5; PROTEIN BCL 2; PROTEIN BCL X; TETRAZOLIUM; THYROID PEROXIDASE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; CELL DEATH; CELL STRUCTURE; COLORIMETRY; CYTOTOXICITY; DNA EXTRACTION; ELECTRON MICROSCOPY; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; GRAVES DISEASE; HASHIMOTO DISEASE; HUMAN; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE; NICK END LABELING; PRIORITY JOURNAL; RELIABILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIBONUCLEASE PROTECTION ASSAY; TECHNIQUE; THYROID CELL;

ANIMALS; ANNEXIN A5; ANTIGENS, CD95; APOPTOSIS; DNA; FAS LIGAND PROTEIN; FLOW CYTOMETRY; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MEMBRANE GLYCOPROTEINS; MICROSCOPY, ELECTRON; THYROID GLAND; THYROIDITIS, AUTOIMMUNE;

EID: 0036644092     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(02)00078-9     Document Type: Article

References (40)

1. Apoptosis
2. Fas (APO-1, CD95)-mediated apoptosis in thyroid cells is regulated by a labile protein inhibitor
3. Apoptosis and autoimmune thyroid disease: Following a TRAIL to thyroid destruction?
4. TRAIL death pathway expression and induction in thyroid follicular cells
5. Immunohistochemical detection of p53 and Bcl-2 proteins in Hashimoto's thyroiditis and primary thyroid lymphomas
6. Rapid in vivo effects of glucocorticoids on the integrity of rat lymphocyte genomic deoxyribonucleic acid
7. Features of apoptotic cells measured by flow cytometry
8. Endogenous endonuclease-induced DNA fragmentation: An early event in cell mediated cytolysis
9. Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells
10. Topoisomerase II binds to ellipticine in the absence or presence of DNA. Characterization of enzyme-drug interactions by fluorescence spectroscopy
11. Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis
12. Differential regulation of Fas-mediated apoptosis in both thyrocyte and lymphocyte cellular compartments correlates with opposite phenotypic manifestations of autoimmune disease
13. Detection of DNA fragmentation in apoptosis: Application of in situ nick translation to cell culture systems and tissue sections
14. Analysis of apoptosis in relation to tissue destruction associated with Hashimoto's autoimmune thyroiditis
15. Apoptosis in thyroid disease
16. Thyrocytes targets and effectors of autoimmunity: A role for death receptors?
17. Functional Fas ligand expression in thyrocytes from patients with Graves' disease
18. Thyroid-stimulating hormone inhibits Fas antigen-mediated apoptosis of human thyrocytes in vitro
19. Apoptosis: A basic biological phenomenon with wide ranging implications in tissue kinetics
20. Apoptosis in thyroid tissue from patients with Hashimoto's thyroiditis
21. Graves-Basedow disease goiter: A model of Bax-Bcl2 regulated apoptosis
22. Fas/Fas ligand up-regulation and Bcl-2 down-regulation may be significant in the pathogenesis of Hashimoto's thyroiditis
23. Fas ligand expression in thyroid follicular cells from patients with thionamide-treated Graves' disease
24. Characterization of FAP-1 expression and function in thyroid follicular cells
25. Importance of DNA fragmentation in apoptosis with regard to TUNEL specificity
26. A rapid and simple method for measuring thyrocyte apoptosis by propidium iodide staining and flow cytometry
27. Death of the autoimmune thyrocytes: Is it pushed or does it jump?
28. An image analysis work station designed for multiple users: Application of quantitative digital imaging techniques to electron microscopy
29. Thyroid cell apoptosis. A new understanding of thyroid autoimmunity
30. Methods for the detection of apoptosis
31. The sensitivity of chromatin from thymuses and spleens of irradiated mice to alkaline solutions
32. Fas/Fas ligand-driven T cell apoptosis as a consequence of ineffective thyroid immunoprivilege in Hashimoto's thyroiditis
33. Control of target cell survival in thyroid autoimmunity by T helper cytokines via regulation of apoptotic proteins
34. Fas-FasL in Hashimoto's thyroiditis
35. Constitutive expression of FasL in thyrocytes
36. CD95 ligand (CD95) immunochemistry: A critical study on 12 antibodies
37. Apoptosis in thyroid disease: A histochemical study
38. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V
39. Autoimmune thyroid disease: Further developments in our understanding
40. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation