Mechanisms of mitochondrial membrane permeabilization

Cell Death and Differentiation

Volumn 7, Issue 12, 2000, Pages 1145-

  Reed, J C ^a   Kroemer, G ^b  

^a BURNHAM INSTITUTE   (United States)

^b INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CYTOCHROME C; GREEN FLUORESCENT PROTEIN; MUTANT PROTEIN; PROTEIN BCL 2;

APOPTOSIS; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELL PROTECTION; EDITORIAL; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; ION TRANSPORT; LIFE; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MITOCHONDRION SWELLING; MODEL; NONHUMAN; PH; PRIORITY JOURNAL; REGULATORY MECHANISM; TECHNIQUE; THEORY;

ANIMALS; APOPTOSIS; CELL MEMBRANE PERMEABILITY; HUMANS; INTRACELLULAR MEMBRANES; MITOCHONDRIA;

EID: 17744376764     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400777     Document Type: Editorial

References (6)

1. Permeabilization of the mitochondrial inner membrane during apoptosis. Impact of the adenine nucleotide translocator
2. Mitochondria-dependent apoptosis and cellular pH regulation
3. Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c
4. VDAC regulation by the Bcl-2 family of proteins
5. The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability
6. The 'harmless' release of cytochrome c