-
2
-
-
0030947095
-
Programmed cell death in animal development
-
Jacobson MD, Weil M, Raff MC: Programmed cell death in animal development. Cell (1997) 88:347-354.
-
(1997)
Cell
, vol.88
, pp. 347-354
-
-
Jacobson, M.D.1
Weil, M.2
Raff, M.C.3
-
3
-
-
0030702084
-
Caspases: Intracellular signaling by proteolysis
-
Salvesen GS, Dixit VM: Caspases: Intracellular signaling by proteolysis. Cell (1997) 91:443-446.
-
(1997)
Cell
, vol.91
, pp. 443-446
-
-
Salvesen, G.S.1
Dixit, V.M.2
-
4
-
-
0027525104
-
The C elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
-
Yuan J, Shaham S, Ledoux S, Ellis HM, Horvitz HR: The C elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell (1993) 75:641-652.
-
(1993)
Cell
, vol.75
, pp. 641-652
-
-
Yuan, J.1
Shaham, S.2
Ledoux, S.3
Ellis, H.M.4
Horvitz, H.R.5
-
5
-
-
15844412409
-
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
-
Muzio M, Chinnaiyan AM, Kischkel FC, O'Rourke K, Shevchenko A, Ni J, Scaffidi C, Bretz JD, Zhang M, Gentz R, Mann M et al: FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell (1996) 85:817-827.
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
O'Rourke, K.4
Shevchenko, A.5
Ni, J.6
Scaffidi, C.7
Bretz, J.D.8
Zhang, M.9
Gentz, R.10
Mann, M.11
-
6
-
-
0031018914
-
FLICE induced apoptosis in a cell-free system. Cleavage of caspase zymogens
-
Muzio M, Salvesen GS, Dixit VM: FLICE induced apoptosis in a cell-free system. Cleavage of caspase zymogens. J Biol Chem (1997) 272:2952-2956.
-
(1997)
J Biol Chem
, vol.272
, pp. 2952-2956
-
-
Muzio, M.1
Salvesen, G.S.2
Dixit, V.M.3
-
7
-
-
0031051502
-
Cloning and expression of a rat brain interleukin-1β-converting enzyme (ICE)-related protease (IRP) and its possible role in apoptosis of cultured cerebellar granule neurons
-
Ni B, Wu X, Du Y, Su Y, Hamilton BE, Rockey PK, Rosteck PJ, Poirier GG, Paul SM: Cloning and expression of a rat brain interleukin-1β-converting enzyme (ICE)-related protease (IRP) and its possible role in apoptosis of cultured cerebellar granule neurons. J Neurosci (1997) 17:1561-1569.
-
(1997)
J Neurosci
, vol.17
, pp. 1561-1569
-
-
Ni, B.1
Wu, X.2
Du, Y.3
Su, Y.4
Hamilton, B.E.5
Rockey, P.K.6
Rosteck, P.J.7
Poirier, G.G.8
Paul, S.M.9
-
8
-
-
0029068871
-
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
-
note
-
Nicholson DW, Ali A, Thornberry NA, Vaillancourt JP, Ding CK, Gallant M, Gareau Y, Griffin PR, Labelle M, Lazebnik YA: Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature (1995) 376:37-43. Demonstration of caspase 3 involvement in apoptosis.
-
(1995)
Nature
, vol.376
, pp. 37-43
-
-
Nicholson, D.W.1
Ali, A.2
Thornberry, N.A.3
Vaillancourt, J.P.4
Ding, C.K.5
Gallant, M.6
Gareau, Y.7
Griffin, P.R.8
Labelle, M.9
Lazebnik, Y.A.10
-
9
-
-
0029787268
-
Molecular ordering of apoptotic mammalian CED-3/ICE-like proteases
-
Orth K, O'Rourke K, Salvesen GS, Dixit VM: Molecular ordering of apoptotic mammalian CED-3/ICE-like proteases. J Biol Chem (1996) 271:20977-20980.
-
(1996)
J Biol Chem
, vol.271
, pp. 20977-20980
-
-
Orth, K.1
O'Rourke, K.2
Salvesen, G.S.3
Dixit, V.M.4
-
10
-
-
0029891838
-
The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A
-
Orth K, Chinnaiyan AM, Garg M, Froelich CJ, Dixit VM: The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A. J Biol Chem (1996) 271:16443-16446.
-
(1996)
J Biol Chem
, vol.271
, pp. 16443-16446
-
-
Orth, K.1
Chinnaiyan, A.M.2
Garg, M.3
Froelich, C.J.4
Dixit, V.M.5
-
11
-
-
0009530192
-
Human ICE/CED-3 protease nomenclature
-
note
-
Alnemri ES, Livingston DJ, Nicholson DW, Salvesen GS, Thomberry NA, Wong WW, Yuan J: Human ICE/CED-3 protease nomenclature. Cell (1995) 87:171. New designation as caspases for ICE-like proteases.
-
(1995)
Cell
, vol.87
, pp. 171
-
-
Alnemri, E.S.1
Livingston, D.J.2
Nicholson, D.W.3
Salvesen, G.S.4
Thomberry, N.A.5
Wong, W.W.6
Yuan, J.7
-
12
-
-
0030814675
-
Caspases: Killer proteases
-
note
-
Nicholson DW, Thornberry NA: Caspases: Killer proteases. Trends Biochem Sci (1997) 22:299-306. Good review of caspase structure and substrate specificity.
-
(1997)
Trends Biochem Sci
, vol.22
, pp. 299-306
-
-
Nicholson, D.W.1
Thornberry, N.A.2
-
13
-
-
0030977847
-
Target protease specificity of the viral serpin CrmA. Analysis of five caspases
-
Zhou Q, Snipas S, Orth K, Muzio M, Dixit VM, Salvesen GS: Target protease specificity of the viral serpin CrmA. Analysis of five caspases. J Biol Chem (1997) 272:7797-7800.
-
(1997)
J Biol Chem
, vol.272
, pp. 7797-7800
-
-
Zhou, Q.1
Snipas, S.2
Orth, K.3
Muzio, M.4
Dixit, V.M.5
Salvesen, G.S.6
-
14
-
-
0030948457
-
Substrate specificities of caspase family proteases
-
Talanian RV, Quinlan C, Trautz S, Hackett MC, Mankovich JA, Banach D, Ghayur T, Brady KD, Wong WW: Substrate specificities of caspase family proteases. J Biol Chem (1997) 272:9677-9682.
-
(1997)
J Biol Chem
, vol.272
, pp. 9677-9682
-
-
Talanian, R.V.1
Quinlan, C.2
Trautz, S.3
Hackett, M.C.4
Mankovich, J.A.5
Banach, D.6
Ghayur, T.7
Brady, K.D.8
Wong, W.W.9
-
15
-
-
0032484008
-
Inhibition of human caspases by peptide-based and macromolecular inhibitors
-
Garcia-Calvo M, Peterson EP, Leiting B, Ruel R, Nicholson DW, Thornberry NA: Inhibition of human caspases by peptide-based and macromolecular inhibitors. J Biol Chem (1998) 273:32608-32613.
-
(1998)
J Biol Chem
, vol.273
, pp. 32608-32613
-
-
Garcia-Calvo, M.1
Peterson, E.P.2
Leiting, B.3
Ruel, R.4
Nicholson, D.W.5
Thornberry, N.A.6
-
16
-
-
0031080252
-
A combinatorial approach for determining protease specificities: Application to interleukin-1β converting enzyme (ICE)
-
Rano TA, Timkey T, Peterson EP, Rotonda J, Nicholson DW, Becker JW, Chapman KT, Thornberry NA: A combinatorial approach for determining protease specificities: Application to interleukin-1β converting enzyme (ICE). Chem Biol (1997) 4:149-155.
-
(1997)
Chem Biol
, vol.4
, pp. 149-155
-
-
Rano, T.A.1
Timkey, T.2
Peterson, E.P.3
Rotonda, J.4
Nicholson, D.W.5
Becker, J.W.6
Chapman, K.T.7
Thornberry, N.A.8
-
17
-
-
0030849093
-
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
-
Thornberry NA, Rano TA, Peterson EP, Rasper DM, Timkey T, Garcia-Calvo M, Houtzager VM, Nordstrom PA, Roy S, Vaillancourt JP, Chapman KT, Nicholson DW: A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J Biol Chem (1997) 272:17907-17911.
-
(1997)
J Biol Chem
, vol.272
, pp. 17907-17911
-
-
Thornberry, N.A.1
Rano, T.A.2
Peterson, E.P.3
Rasper, D.M.4
Timkey, T.5
Garcia-Calvo, M.6
Houtzager, V.M.7
Nordstrom, P.A.8
Roy, S.9
Vaillancourt, J.P.10
Chapman, K.T.11
Nicholson, D.W.12
-
18
-
-
0030897988
-
Substrate and inhibitor specificity of interleukin-1β-converting enzyme and related caspases
-
Margolin N, Raybuck SA, Wilson KP, Chen W, Fox T, Gu Y, Livingston DJ: Substrate and inhibitor specificity of interleukin-1β-converting enzyme and related caspases. J Biol Chem (1997) 272:7223-7228.
-
(1997)
J Biol Chem
, vol.272
, pp. 7223-7228
-
-
Margolin, N.1
Raybuck, S.A.2
Wilson, K.P.3
Chen, W.4
Fox, T.5
Gu, Y.6
Livingston, D.J.7
-
19
-
-
0032945917
-
Caspases in apoptotic death
-
Denner L: Caspases in apoptotic death. Exp Opin Invest Drugs (1999) 8:37-50.
-
(1999)
Exp Opin Invest Drugs
, vol.8
, pp. 37-50
-
-
Denner, L.1
-
20
-
-
0034764332
-
Caspases: Recent advances in small molecule inhibitors
-
note
-
Ashwell S: Caspases: Recent advances in small molecule inhibitors. Exp Opin Ther Patents (2001) 11:1593-1603. Excellent review of caspase patent literature up to April 2001.
-
(2001)
Exp Opin Ther Patents
, vol.11
, pp. 1593-1603
-
-
Ashwell, S.1
-
21
-
-
0034717269
-
Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality
-
Lee D, Long SA, Adams JL, Chan G, Vaidya KS, Francis TA, Kikly K, Winkler JD, Sung C-M, Debouck C, Richardson S et al: Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality. J Biol Chem (2000) 275:16007-16014.
-
(2000)
J Biol Chem
, vol.275
, pp. 16007-16014
-
-
Lee, D.1
Long, S.A.2
Adams, J.L.3
Chan, G.4
Vaidya, K.S.5
Francis, T.A.6
Kikly, K.7
Winkler, J.D.8
Sung, C.-M.9
Debouck, C.10
Richardson, S.11
-
23
-
-
0033921961
-
Caspase requirement for neuronal apoptosis and neurodegeneration
-
Nicotera P: Caspase requirement for neuronal apoptosis and neurodegeneration. IUBMB Life (2000) 49:421-425.
-
(2000)
IUBMB Life
, vol.49
, pp. 421-425
-
-
Nicotera, P.1
-
24
-
-
0032876951
-
Neuroprotection by caspase inhibitors
-
note
-
Braun JS, Tuomanen EI, Cleveland JL: Neuroprotection by caspase inhibitors. Exp Opin Invest Drugs (1999) 8:1599-1610. Good, broad-based review of the evidence for caspase inhibitor neuroprotection in a number of neurodegenerative conditions.
-
(1999)
Exp Opin Invest Drugs
, vol.8
, pp. 1599-1610
-
-
Braun, J.S.1
Tuomanen, E.I.2
Cleveland, J.L.3
-
25
-
-
0029912056
-
Mechanisms of neuronal death in Alzheimer's disease
-
Cotman CW, Su JH: Mechanisms of neuronal death in Alzheimer's disease. Brain Pathol (1996) 6:493-506.
-
(1996)
Brain Pathol
, vol.6
, pp. 493-506
-
-
Cotman, C.W.1
Su, J.H.2
-
26
-
-
0035917831
-
Activated caspase-3 expression in Alzheimer's and aged control brain: Correlation with Alzheimer pathology
-
Su JH, Zhao M, Anderson AJ, Srinivasan A, Cotman CW: Activated caspase-3 expression in Alzheimer's and aged control brain: Correlation with Alzheimer pathology. Brain Res (2001) 898:350-357.
-
(2001)
Brain Res
, vol.898
, pp. 350-357
-
-
Su, J.H.1
Zhao, M.2
Anderson, A.J.3
Srinivasan, A.4
Cotman, C.W.5
-
27
-
-
0028577208
-
Immunohistochemical evidence for apoptosis in Alzheimer's disease
-
Su JH, Anderson AJ, Cummings BJ, Cotman CW: Immunohistochemical evidence for apoptosis in Alzheimer's disease. Neuroreport (1994) 5:2529-2533.
-
(1994)
Neuroreport
, vol.5
, pp. 2529-2533
-
-
Su, J.H.1
Anderson, A.J.2
Cummings, B.J.3
Cotman, C.W.4
-
28
-
-
0029942337
-
Histochemical detection of apoptosis in Parkinson's disease
-
Mochizuki H, Goto K, Mori H, Mizuno Y: Histochemical detection of apoptosis in Parkinson's disease. J Neurol Sci (1996) 137:120-123.
-
(1996)
J Neurol Sci
, vol.137
, pp. 120-123
-
-
Mochizuki, H.1
Goto, K.2
Mori, H.3
Mizuno, Y.4
-
29
-
-
0034926105
-
Does neuronal loss in Parkinson's disease involve programmed cell death?
-
Andersen JK: Does neuronal loss in Parkinson's disease involve programmed cell death? Bioessays (2001) 23:640-646.
-
(2001)
Bioessays
, vol.23
, pp. 640-646
-
-
Andersen, J.K.1
-
30
-
-
12944250987
-
Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease
-
Hartmann A, Hunot S, Michel PP, Muriel MP, Vyas S, Faucheux BA, Mouatt-Prigent A, Turmel H, Srinivasan A, Ruberg M, Evan GI et al: Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease. Proc Natl Acad Sci USA (2000) 97:2875-2880.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 2875-2880
-
-
Hartmann, A.1
Hunot, S.2
Michel, P.P.3
Muriel, M.P.4
Vyas, S.5
Faucheux, B.A.6
Mouatt-Prigent, A.7
Turmel, H.8
Srinivasan, A.9
Ruberg, M.10
Evan, G.I.11
-
31
-
-
0035894881
-
Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease
-
Viswanath V, Wu YQ, Boonplueang R, Chen S, Stevenson FF, Yantiri F, Yang LC, Beal MF, Andersen JK: Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease. J Neurosci (2001) 21:9519-9528.
-
(2001)
J Neurosci
, vol.21
, pp. 9519-9528
-
-
Viswanath, V.1
Wu, Y.Q.2
Boonplueang, R.3
Chen, S.4
Stevenson, F.F.5
Yantiri, F.6
Yang, L.C.7
Beal, M.F.8
Andersen, J.K.9
-
32
-
-
0002974258
-
Apoptosis: Its relevance to Parkinson's disease
-
note
-
Schulz JB, Gerhardt E: Apoptosis: Its relevance to Parkinson's disease. Clin Neurosci Research (2001) 1:427-433. Good reviews of the evidence for apoptosis in Parkinson's disease.
-
(2001)
Clin Neurosci Research
, vol.1
, pp. 427-433
-
-
Schulz, J.B.1
Gerhardt, E.2
-
33
-
-
0021829406
-
Permanent human parkinsonism due to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): Seven cases
-
Ballard PA, Tetrud JW, Langston JW: Permanent human parkinsonism due to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): Seven cases. Neurology (1985) 35:949-956.
-
(1985)
Neurology
, vol.35
, pp. 949-956
-
-
Ballard, P.A.1
Tetrud, J.W.2
Langston, J.W.3
-
34
-
-
0021893798
-
Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) in the mouse: Relationships between monoamine oxidase, MPTP metabolism and neurotoxicity
-
Heikkila RE, Hess A, Duvoisin RC: Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) in the mouse: Relationships between monoamine oxidase, MPTP metabolism and neurotoxicity. Life Sci (1985) 36:231-236.
-
(1985)
Life Sci
, vol.36
, pp. 231-236
-
-
Heikkila, R.E.1
Hess, A.2
Duvoisin, R.C.3
-
35
-
-
0022363325
-
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and several of its analogues on the dopaminergic nigrostriatal pathway in mice
-
Heikkila RE, Manzino L, Cabbat FS, Duvoisin RC: Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and several of its analogues on the dopaminergic nigrostriatal pathway in mice. Neurosci Lett (1985) 58:133-137.
-
(1985)
Neurosci Lett
, vol.58
, pp. 133-137
-
-
Heikkila, R.E.1
Manzino, L.2
Cabbat, F.S.3
Duvoisin, R.C.4
-
36
-
-
0021155228
-
MPTP-induced parkinsonism in human and non-human primates - Clinical and experimental aspects
-
Langston JW, Langston EB, Irwin I: MPTP-induced parkinsonism in human and non-human primates - Clinical and experimental aspects. Acta Neurol Scand Suppl (1984) 100:49-54.
-
(1984)
Acta Neurol Scand Suppl
, vol.100
, pp. 49-54
-
-
Langston, J.W.1
Langston, E.B.2
Irwin, I.3
-
37
-
-
0021182244
-
Pargyline prevents MPTP-induced parkinsonism in primates
-
Langston JW, Irwin I, Langston EB, Forno LS: Pargyline prevents MPTP-induced parkinsonism in primates. Science (1984) 225:1480-1482.
-
(1984)
Science
, vol.225
, pp. 1480-1482
-
-
Langston, J.W.1
Irwin, I.2
Langston, E.B.3
Forno, L.S.4
-
38
-
-
0021893794
-
+ in the substantia nigra: A key to neurotoxicity?
-
+ in the substantia nigra: A key to neurotoxicity? Life Sci (1985) 36:207-212.
-
(1985)
Life Sci
, vol.36
, pp. 207-212
-
-
Irwin, I.1
Langston, J.W.2
-
41
-
-
0021865454
-
1-Methyl-4-phenylpyridine (MPP+) is toxic to mesencephalic dopamine neurons in culture
-
Mytilineou C, Cohen G, Heikkila RE: 1-Methyl-4-phenylpyridine (MPP+) is toxic to mesencephalic dopamine neurons in culture. Neurosci Lett (1985) 57:19-24.
-
(1985)
Neurosci Lett
, vol.57
, pp. 19-24
-
-
Mytilineou, C.1
Cohen, G.2
Heikkila, R.E.3
-
42
-
-
0022969072
-
+) but not 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) selectively destroys dopaminergic neurons in cultures of dissociated rat mesencephalic neurons
-
+) but not 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) selectively destroys dopaminergic neurons in cultures of dissociated rat mesencephalic neurons. Neurosci Lett (1986) 72:215-220.
-
(1986)
Neurosci Lett
, vol.72
, pp. 215-220
-
-
Sanchez Ramos, J.1
Barrett, J.N.2
Goldstein, M.3
Weiner, W.J.4
Hefti, F.5
-
43
-
-
0035297146
-
Caspase-3 activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice
-
Turmel H, Hartmann A, Parain K, Douhou A, Srinivasan A, Agid Y, Hirsch EC: Caspase-3 activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice. Mov Disord (2001) 16:185-189.
-
(2001)
Mov Disord
, vol.16
, pp. 185-189
-
-
Turmel, H.1
Hartmann, A.2
Parain, K.3
Douhou, A.4
Srinivasan, A.5
Agid, Y.6
Hirsch, E.C.7
-
44
-
-
0035313071
-
Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis
-
Hartmann A, Troadec JD, Hunot S, Kikly K, Faucheux BA, Moautt-Prigent A, Ruberg M, Agid Y, Hirsch EC: Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis. J Neurosci (2001) 21:2247-2255.
-
(2001)
J Neurosci
, vol.21
, pp. 2247-2255
-
-
Hartmann, A.1
Troadec, J.D.2
Hunot, S.3
Kikly, K.4
Faucheux, B.A.5
Moautt-Prigent, A.6
Ruberg, M.7
Agid, Y.8
Hirsch, E.C.9
-
45
-
-
0035894881
-
Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease
-
Viswanath V, Wu Y, Boonplueang R, Chen S, Stevenson FF, Yantiri F, Yang L, Beal MF, Andersen JK: Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease. J Neurosci (2001) 21:9519-9528.
-
(2001)
J Neurosci
, vol.21
, pp. 9519-9528
-
-
Viswanath, V.1
Wu, Y.2
Boonplueang, R.3
Chen, S.4
Stevenson, F.F.5
Yantiri, F.6
Yang, L.7
Beal, M.F.8
Andersen, J.K.9
-
46
-
-
0031834955
-
Peptide inhibitors of caspase-3-like proteases attenuate 1-methyl-4-phenylpyridinum-induced toxicity of cultured fetal rat mesencephalic dopamine neurons
-
Dodel RC, Du Y, Bales KR, Ling ZD, Carvey PM, Paul SM: Peptide inhibitors of caspase-3-like proteases attenuate 1-methyl-4-phenylpyridinum-induced toxicity of cultured fetal rat mesencephalic dopamine neurons. Neuroscience (1998) 86:701-707.
-
(1998)
Neuroscience
, vol.86
, pp. 701-707
-
-
Dodel, R.C.1
Du, Y.2
Bales, K.R.3
Ling, Z.D.4
Carvey, P.M.5
Paul, S.M.6
-
47
-
-
0036549215
-
Caspase inhibitors attenuate 1-methyl-4-phenylpyridinium toxicity in primary cultures of mesencephalic dopaminergic neurons
-
Bisland J, Roy S, Xanthoudakis S, Nicholson DW, Han Y, Grimm E, Hefti F, Harper SJ: Caspase inhibitors attenuate 1-methyl-4-phenylpyridinium toxicity in primary cultures of mesencephalic dopaminergic neurons. J Neurosci (2002) 22:2637-2649.
-
(2002)
J Neurosci
, vol.22
, pp. 2637-2649
-
-
Bisland, J.1
Roy, S.2
Xanthoudakis, S.3
Nicholson, D.W.4
Han, Y.5
Grimm, E.6
Hefti, F.7
Harper, S.J.8
-
48
-
-
0035313071
-
Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis
-
Hartmann A, Troadec JD, Hunot S, Kikly K, Faucheux BA, Mouatt-Prigent A, Ruberg M, Agid Y, Hirsch EC: Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis. J Neurosci 21:2247-2255.
-
J Neurosci
, vol.21
, pp. 2247-2255
-
-
Hartmann, A.1
Troadec, J.D.2
Hunot, S.3
Kikly, K.4
Faucheux, B.A.5
Mouatt-Prigent, A.6
Ruberg, M.7
Agid, Y.8
Hirsch, E.C.9
-
49
-
-
5944251623
-
Caspase inhibitors improve survival in sepsis: A critical role of the lymphocyte
-
Hotchkiss RS, Chang KC, Swanson PE, Tinsley KW, Hui JJ, Klender P, Xanthoudakis S, Roy S, Black C, Grimm E, Aspiotis R et al: Caspase inhibitors improve survival in sepsis: A critical role of the lymphocyte. Nat Immunol (2000) 1:496-501.
-
(2000)
Nat Immunol
, vol.1
, pp. 496-501
-
-
Hotchkiss, R.S.1
Chang, K.C.2
Swanson, P.E.3
Tinsley, K.W.4
Hui, J.J.5
Klender, P.6
Xanthoudakis, S.7
Roy, S.8
Black, C.9
Grimm, E.10
Aspiotis, R.11
-
51
-
-
0033557640
-
Distinct mechanisms underlie neurotoxin-mediated cell death in cultured dopaminergic neurons
-
Lotharius J, Dugan LL, O'Malley KL: Distinct mechanisms underlie neurotoxin-mediated cell death in cultured dopaminergic neurons. J Neurosci (1999) 19:1284-1293.
-
(1999)
J Neurosci
, vol.19
, pp. 1284-1293
-
-
Lotharius, J.1
Dugan, L.L.2
O'Malley, K.L.3
-
52
-
-
0033168508
-
+-induced dopaminergic neuronal cell death: Role of caspases, ROS, and JNK
-
+-induced dopaminergic neuronal cell death: Role of caspases, ROS, and JNK. J Neurosci Res (1999) 57:86-94.
-
(1999)
J Neurosci Res
, vol.57
, pp. 86-94
-
-
Choi, W.S.1
Yoon, S.Y.2
Oh, T.H.3
Choi, E.J.4
O'Malley, K.L.5
Oh, Y.J.6
-
53
-
-
0035085211
-
Rescue from death but not from functional impairment: Caspase inhibition protects dopaminergic cells against 6-hydroxydopamine-induced apoptosis but not against the loss of their terminals
-
Von Coelln R, Kugler S, Bahr M, Weller M, Dichgans J, Schulz JB: Rescue from death but not from functional impairment: Caspase inhibition protects dopaminergic cells against 6-hydroxydopamine-induced apoptosis but not against the loss of their terminals. J Neurochem (2001) 77:263-273.
-
(2001)
J Neurochem
, vol.77
, pp. 263-273
-
-
Von Coelln, R.1
Kugler, S.2
Bahr, M.3
Weller, M.4
Dichgans, J.5
Schulz, J.B.6
-
54
-
-
0034671450
-
Protection by synergistic effects of adenovirus-mediated X-chromosome-linked inhibitor of apoptosis and glial cell line-derived neurotrophic factor gene transfer in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease
-
note
-
Eberhardt O, Coelln RV, Kugler S, Lindenau J, Rathke-Hartlieb S, Gerhardt E, Haid S, Isenmann S, Gravel C, Srinivasan A, Bahr M et al: Protection by synergistic effects of adenovirus-mediated X-chromosome-linked inhibitor of apoptosis and glial cell line-derived neurotrophic factor gene transfer in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. J Neurosci (2000) 20:9126-9134. Demonstration that caspase inhibition by XIAP overexpression spares cell somata in the MPTP mouse PD model, but additional trophic support is required to spare striatal innervation.
-
(2000)
J Neurosci
, vol.20
, pp. 9126-9134
-
-
Eberhardt, O.1
Coelln, R.V.2
Kugler, S.3
Lindenau, J.4
Rathke-Hartlieb, S.5
Gerhardt, E.6
Haid, S.7
Isenmann, S.8
Gravel, C.9
Srinivasan, A.10
Bahr, M.11
-
55
-
-
0033588531
-
Caspase inhibition protects nigral neurons against 6-OHDA-induced retrograde degeneration
-
Cutillas B, Espejo M, Gil J, Ferrer I, Ambrosio S: Caspase inhibition protects nigral neurons against 6-OHDA-induced retrograde degeneration. Neuroreport (1999) 10:2605-2608.
-
(1999)
Neuroreport
, vol.10
, pp. 2605-2608
-
-
Cutillas, B.1
Espejo, M.2
Gil, J.3
Ferrer, I.4
Ambrosio, S.5
-
56
-
-
0032531886
-
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2
-
Yang L, Matthews RT, Schulz JB, Klockgether T, Liao AW, Martinou JC, Penney JB Jr, Hyman BT, Beal MF: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2. J Neurosci (1998) 18:8145-8152.
-
(1998)
J Neurosci
, vol.18
, pp. 8145-8152
-
-
Yang, L.1
Matthews, R.T.2
Schulz, J.B.3
Klockgether, T.4
Liao, A.W.5
Martinou, J.C.6
Penney J.B., Jr.7
Hyman, B.T.8
Beal, M.F.9
-
57
-
-
0032510758
-
Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity
-
Offen D, Beart PM, Cheung NS, Pascoe CJ, Hochman A, Gorodin S, Melamed E, Bernard R, Bernard O: Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. Proc Natl Acad Sci USA (1998) 95:5789-5794.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 5789-5794
-
-
Offen, D.1
Beart, P.M.2
Cheung, N.S.3
Pascoe, C.J.4
Hochman, A.5
Gorodin, S.6
Melamed, E.7
Bernard, R.8
Bernard, O.9
-
58
-
-
0034883987
-
NAIP protects the nigrostriatal dopamine pathway in an intrastriatal 6-OHDA rat model of Parkinson's disease
-
Crocker SJ, Wigle N, Liston P, Thompson CS, Lee C, Xu DG, Roy S, Nicholson DW, Park DS, MacKenzie A, Korneluck RG, Robertson GS: NAIP protects the nigrostriatal dopamine pathway in an intrastriatal 6-OHDA rat model of Parkinson's disease. Eur J Neurosci (2001) 14:391-400.
-
(2001)
Eur J Neurosci
, vol.14
, pp. 391-400
-
-
Crocker, S.J.1
Wigle, N.2
Liston, P.3
Thompson, C.S.4
Lee, C.5
Xu, D.G.6
Roy, S.7
Nicholson, D.W.8
Park, D.S.9
MacKenzie, A.10
Korneluck, R.G.11
Robertson, G.S.12
-
59
-
-
0033601995
-
Transgenic mice expressing a dominant negative mutant interleukin-1β converting enzyme show resistance to MPTP neurotoxicity
-
Klevenyi P, Andreassen O, Ferrante RJ, Schleicher JR Jr, Friedlander RM, Beal MF: Transgenic mice expressing a dominant negative mutant interleukin-1β converting enzyme show resistance to MPTP neurotoxicity. Neuroreport (1999) 10:635-638.
-
(1999)
Neuroreport
, vol.10
, pp. 635-638
-
-
Klevenyi, P.1
Andreassen, O.2
Ferrante, R.J.3
Schleicher J.R., Jr.4
Friedlander, R.M.5
Beal, M.F.6
-
60
-
-
0035964358
-
Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease
-
Xia XG, Harding T, Weller M, Bieneman A, Uney JB, Schulz JB: Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease. Proc Natl Acad Sci USA (2001) 98:10433-10438.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10433-10438
-
-
Xia, X.G.1
Harding, T.2
Weller, M.3
Bieneman, A.4
Uney, J.B.5
Schulz, J.B.6
-
61
-
-
0029773397
-
An ICE inhibitor, (Z)-VAD-DCB attenuates ischaemic brain damage in the rat
-
note
-
Loddick SA, MacKenzie A, Rothwell NJ: An ICE inhibitor, (Z)-VAD-DCB attenuates ischaemic brain damage in the rat. Neuroreport (1996) 7:1465-1468. First demonstration of neuroprotection by caspase inhibition in an ischemic model.
-
(1996)
Neuroreport
, vol.7
, pp. 1465-1468
-
-
Loddick, S.A.1
MacKenzie, A.2
Rothwell, N.J.3
-
62
-
-
0030614952
-
Inhibition of interleukin 1β converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage
-
Hara H, Friedlander RM, Gagliardini V, Ayata C, Fink K, Huang Z, Shimizu-Sasamata M, Yuan J, Moskowitz MA: Inhibition of interleukin 1β converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage. Proc Natl Acad Sci USA (1997) 94:2007-2012.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2007-2012
-
-
Hara, H.1
Friedlander, R.M.2
Gagliardini, V.3
Ayata, C.4
Fink, K.5
Huang, Z.6
Shimizu-Sasamata, M.7
Yuan, J.8
Moskowitz, M.A.9
-
63
-
-
0032080673
-
Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury
-
Cheng Y, Deshmukth M, D'Costa A, Demaro JA, Gidday JM, Shah A, Sun Y, Jacquin MF, Johnson EM, Holtzman DM: Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury. J Clin Invest (1998) 101:1992-1999.
-
(1998)
J Clin Invest
, vol.101
, pp. 1992-1999
-
-
Cheng, Y.1
Deshmukth, M.2
D'Costa, A.3
Demaro, J.A.4
Gidday, J.M.5
Shah, A.6
Sun, Y.7
Jacquin, M.F.8
Johnson, E.M.9
Holtzman, D.M.10
-
64
-
-
0034131832
-
Protective effect of a caspase inhibitor in models for cerebral ischemia in vitro and in vivo
-
Wiessner C, Sauer D, Alaimo D, Allegrini PR: Protective effect of a caspase inhibitor in models for cerebral ischemia in vitro and in vivo. Cell Mol Biol (2000) 46:53-62.
-
(2000)
Cell Mol Biol
, vol.46
, pp. 53-62
-
-
Wiessner, C.1
Sauer, D.2
Alaimo, D.3
Allegrini, P.R.4
-
66
-
-
0033510160
-
Mice deficient in interleukin-1 converting enzyme are resistant to neonatal hypoxic-ischemic brain damage
-
Liu XH, Kwon D, Schielke GP, Yang GY, Silverstein FS, Barks JD: Mice deficient in interleukin-1 converting enzyme are resistant to neonatal hypoxic-ischemic brain damage. J Cereb Blood Flow Metab (1999) 19:1099-1108.
-
(1999)
J Cereb Blood Flow Metab
, vol.19
, pp. 1099-1108
-
-
Liu, X.H.1
Kwon, D.2
Schielke, G.P.3
Yang, G.Y.4
Silverstein, F.S.5
Barks, J.D.6
-
67
-
-
8044252166
-
Expression of a dominant negative mutant of interleukin-1β converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury
-
Friedlander RM, Gagliardini V, Hara H, Fink KB, Li W, Macdonald G, Fishman MC, Greenberg AH, Moskowitz MA, Yuan J: Expression of a dominant negative mutant of interleukin-1β converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury. J Exp Med (1997) 185:933-940.
-
(1997)
J Exp Med
, vol.185
, pp. 933-940
-
-
Friedlander, R.M.1
Gagliardini, V.2
Hara, H.3
Fink, K.B.4
Li, W.5
Macdonald, G.6
Fishman, M.C.7
Greenberg, A.H.8
Moskowitz, M.A.9
Yuan, J.10
-
68
-
-
0030972543
-
Attenuation of transient focal cerebral ischemic injury in transgenic mice expressing a mutant ICE inhibitory protein
-
Hara H, Fink K, Endres M, Friedlander RM, Gagliardini V, Yuan J, Moskowitz MA: Attenuation of transient focal cerebral ischemic injury in transgenic mice expressing a mutant ICE inhibitory protein. J Cereb Blood Flow Metab (1997) 17:370-375.
-
(1997)
J Cereb Blood Flow Metab
, vol.17
, pp. 370-375
-
-
Hara, H.1
Fink, K.2
Endres, M.3
Friedlander, R.M.4
Gagliardini, V.5
Yuan, J.6
Moskowitz, M.A.7
-
69
-
-
0034660250
-
Inhibition of caspase-1-like activity by Ac-Tyr-Val-Ala-Asp-chloromethyl ketone induces long-lasting neuroprotection in cerebral ischemia through apoptosis reduction and decrease of proinflammatory cytokines
-
Rabuffetti M, Sciorati C, Tarozzo G, Clementi E, Manfredi AA, Beltramo M: Inhibition of caspase-1-like activity by Ac-Tyr-Val-Ala-Asp-chloromethyl ketone induces long-lasting neuroprotection in cerebral ischemia through apoptosis reduction and decrease of proinflammatory cytokines. J Neurosci (2000) 20:4398-4404.
-
(2000)
J Neurosci
, vol.20
, pp. 4398-4404
-
-
Rabuffetti, M.1
Sciorati, C.2
Tarozzo, G.3
Clementi, E.4
Manfredi, A.A.5
Beltramo, M.6
-
70
-
-
0036138936
-
Interleukin-1 influences ischemic brain damage in the mouse independently of the interleukin-1 type I receptor
-
Touzani O, Boutin H, LeFeuvre R, Paker L, Miller A, Luheshi G, Rothwell N: Interleukin-1 influences ischemic brain damage in the mouse independently of the interleukin-1 type I receptor. J Neurosci (2002) 22:38-43.
-
(2002)
J Neurosci
, vol.22
, pp. 38-43
-
-
Touzani, O.1
Boutin, H.2
LeFeuvre, R.3
Paker, L.4
Miller, A.5
Luheshi, G.6
Rothwell, N.7
-
71
-
-
0031718374
-
Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activation
-
Fink K, Zhu J, Namura S, Shimizu-Sasamata M, Endres M, Ma J, Dalkara T, Yuan J, Moskowitz MA: Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activation. J Cereb Blood Flow Metab (1998) 18:1071-1076.
-
(1998)
J Cereb Blood Flow Metab
, vol.18
, pp. 1071-1076
-
-
Fink, K.1
Zhu, J.2
Namura, S.3
Shimizu-Sasamata, M.4
Endres, M.5
Ma, J.6
Dalkara, T.7
Yuan, J.8
Moskowitz, M.A.9
-
72
-
-
0034944956
-
Long-term protection of brain tissue from cerebral ischemia by peripherally administered peptidomimetic caspase inhibitors
-
note
-
Deckwerth TL, Adams LM, Wiessner C, Allegrini P, Rudin M, Sauter A, Hengerer B, Sayers RO, Rovelli G, Aja T, May R et al: Long-term protection of brain tissue from cerebral ischemia by peripherally administered peptidomimetic caspase inhibitors. Drug Dev Res (2001) 52:579-586. Peripheral administration of a novel caspase inhibitor developed by Idun Pharmaceuticals attenuates cerebral ischemic damage.
-
(2001)
Drug Dev Res
, vol.52
, pp. 579-586
-
-
Deckwerth, T.L.1
Adams, L.M.2
Wiessner, C.3
Allegrini, P.4
Rudin, M.5
Sauter, A.6
Hengerer, B.7
Sayers, R.O.8
Rovelli, G.9
Aja, T.10
May, R.11
-
73
-
-
0242663945
-
Selective, reversible caspase-3 inhibitor is neuroprotective and reveals distinct pathways of cell death after neonatal hypoxic-ischemic brain injury
-
Han BH, Xu D, Choi J, Han Y, Xanthoudakis S, Roy S, Tam J, Vaillancourt J, Colucci J, Siman R, Giroux A et al: Selective, reversible caspase-3 inhibitor is neuroprotective and reveals distinct pathways of cell death after neonatal hypoxic-ischemic brain injury. J Biol Chem (2002) 277(33):30128-30136.
-
(2002)
J Biol Chem
, vol.277
, Issue.33
, pp. 30128-30136
-
-
Han, B.H.1
Xu, D.2
Choi, J.3
Han, Y.4
Xanthoudakis, S.5
Roy, S.6
Tam, J.7
Vaillancourt, J.8
Colucci, J.9
Siman, R.10
Giroux, A.11
-
74
-
-
0030848529
-
Evaluation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus
-
Xu DG, Crocker SJ, Doucet JP, St. Jean M, Tamai K, Hakim AM, Ikeda JE, Liston P, Thompson CS, Korneluk RG, MacKenzie A, Robertson GS: Evaluation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus. Nat Med (1997) 3:997-1004.
-
(1997)
Nat Med
, vol.3
, pp. 997-1004
-
-
Xu, D.G.1
Crocker, S.J.2
Doucet, J.P.3
St. Jean, M.4
Tamai, K.5
Hakim, A.M.6
Ikeda, J.E.7
Liston, P.8
Thompson, C.S.9
Korneluk, R.G.10
MacKenzie, A.11
Robertson, G.S.12
-
75
-
-
0033564780
-
Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein overexpression in the rat hippocampus
-
Xu D, Bureau Y, McIntyre DC, Nicholson DW, Liston P, Zhu Y, Fong WG, Crocker SJ, Korneluk RG, Robertson GS: Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein overexpression in the rat hippocampus. J Neurosci (1999) 19:5026-5033.
-
(1999)
J Neurosci
, vol.19
, pp. 5026-5033
-
-
Xu, D.1
Bureau, Y.2
McIntyre, D.C.3
Nicholson, D.W.4
Liston, P.5
Zhu, Y.6
Fong, W.G.7
Crocker, S.J.8
Korneluk, R.G.9
Robertson, G.S.10
-
76
-
-
0031806280
-
Synergistic effects of caspase inhibitors and MK-801 in brain injury after transient focal cerebral ischaemia in mice
-
Ma J, Endres M, Moskowitz MA: Synergistic effects of caspase inhibitors and MK-801 in brain injury after transient focal cerebral ischaemia in mice. Br J Pharmacol (1998) 124:756-762.
-
(1998)
Br J Pharmacol
, vol.124
, pp. 756-762
-
-
Ma, J.1
Endres, M.2
Moskowitz, M.A.3
-
77
-
-
0032768248
-
Inhibition of caspases prevents cell death of hippocampal CA1 neurons, but not impairment of hippocampal long-term potentiation following global ischemia
-
Gillardon F, Kiprianova I, Sandkuhler J, Hossmann KA, Spranger M: Inhibition of caspases prevents cell death of hippocampal CA1 neurons, but not impairment of hippocampal long-term potentiation following global ischemia. Neuroscience (1999) 93:1219-1222.
-
(1999)
Neuroscience
, vol.93
, pp. 1219-1222
-
-
Gillardon, F.1
Kiprianova, I.2
Sandkuhler, J.3
Hossmann, K.A.4
Spranger, M.5
-
78
-
-
0035398570
-
Is caspase-3 inhibition a valid therapeutic strategy in cerebral ischemia?
-
note
-
Loetscher H, Niederhauser O, Kemp J, Gill R: Is caspase-3 inhibition a valid therapeutic strategy in cerebral ischemia? Drug Disc Today (2001) 6:671-680. Review of evidence against caspase inhibition as a therapeutic strategy in cerebral ischemia.
-
(2001)
Drug Disc Today
, vol.6
, pp. 671-680
-
-
Loetscher, H.1
Niederhauser, O.2
Kemp, J.3
Gill, R.4
-
79
-
-
0032543146
-
Inhibitors of interleukin-1β-converting enzyme-family proteases (caspases) prevent apoptosis without affecting decreased cellular ability to reduce 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide in cerebellar granule neurons
-
Harada J, Sugimoto M: Inhibitors of interleukin-1β-converting enzyme-family proteases (caspases) prevent apoptosis without affecting decreased cellular ability to reduce 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide in cerebellar granule neurons. Brain Res (1998) 793:231-243.
-
(1998)
Brain Res
, vol.793
, pp. 231-243
-
-
Harada, J.1
Sugimoto, M.2
-
80
-
-
0036479052
-
Mitochondrial disappearance from cells: A clue to the role of autophagy in programmed cell death and disease?
-
Tolkovsky AM, Xue L, Fletcher GC, Borutaite V: Mitochondrial disappearance from cells: A clue to the role of autophagy in programmed cell death and disease? Biochimie (2002) 84:233-240.
-
(2002)
Biochimie
, vol.84
, pp. 233-240
-
-
Tolkovsky, A.M.1
Xue, L.2
Fletcher, G.C.3
Borutaite, V.4
-
81
-
-
0035814933
-
Mitochondria are selectively eliminated from eukaryotic cells after blockade of caspases during apoptosis
-
Xue L, Fletcher GC, Tolkovsky AM: Mitochondria are selectively eliminated from eukaryotic cells after blockade of caspases during apoptosis. Curr Biol (2001) 11:361-365.
-
(2001)
Curr Biol
, vol.11
, pp. 361-365
-
-
Xue, L.1
Fletcher, G.C.2
Tolkovsky, A.M.3
-
82
-
-
0032870475
-
Autophagy is activated by apoptotic signalling in sympathetic neurons: An alternative mechanism of death execution
-
Xue L, Fletcher GC, Tolkovsky AM: Autophagy is activated by apoptotic signalling in sympathetic neurons: An alternative mechanism of death execution. Mol Cell Neurosci (1999) 14:180-198.
-
(1999)
Mol Cell Neurosci
, vol.14
, pp. 180-198
-
-
Xue, L.1
Fletcher, G.C.2
Tolkovsky, A.M.3
-
83
-
-
0036024018
-
Cleavage of plasma membrane calcium pumps by caspases: A link between apoptosis and necrosis
-
Schwab BL, Guerini D, Didszun C, Bano D, Ferrando-May E, Fava E, Tam J, Xu D, Xanthoudakis S, Nicholson DW, Carafoli E, Nicotera P: Cleavage of plasma membrane calcium pumps by caspases: A link between apoptosis and necrosis. Cell Death Differ (2002) 9:818-831.
-
(2002)
Cell Death Differ
, vol.9
, pp. 818-831
-
-
Schwab, B.L.1
Guerini, D.2
Didszun, C.3
Bano, D.4
Ferrando-May, E.5
Fava, E.6
Tam, J.7
Xu, D.8
Xanthoudakis, S.9
Nicholson, D.W.10
Carafoli, E.11
Nicotera, P.12
-
84
-
-
0035433420
-
Four deaths and a funeral: From caspases to alternative mechanisms
-
Leist M, Jaattela M: Four deaths and a funeral: From caspases to alternative mechanisms. Nat Rev Mol Cell Biol (2001) 2:589-598.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 589-598
-
-
Leist, M.1
Jaattela, M.2
-
85
-
-
0034074468
-
Energy requirement for caspase activation and neuronal cell death
-
Nicotera P, Leist M, Fava E, Berliocchi L, Volbracht C: Energy requirement for caspase activation and neuronal cell death. Brain Pathol (2000) 10:276-282.
-
(2000)
Brain Pathol
, vol.10
, pp. 276-282
-
-
Nicotera, P.1
Leist, M.2
Fava, E.3
Berliocchi, L.4
Volbracht, C.5
-
86
-
-
0030756576
-
Caspases: A treatment target for neurodegenerative disease?
-
Holtzman DM, Deshmukh M: Caspases: A treatment target for neurodegenerative disease? Nat Med (1997) 3:954-955.
-
(1997)
Nat Med
, vol.3
, pp. 954-955
-
-
Holtzman, D.M.1
Deshmukh, M.2
-
87
-
-
0029022365
-
Involvement of an ICE-like protease in Fas-mediated apoptosis
-
Enari M, Hug H, Nagata S: Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature (1995) 375:78-81.
-
(1995)
Nature
, vol.375
, pp. 78-81
-
-
Enari, M.1
Hug, H.2
Nagata, S.3
-
88
-
-
0031018914
-
FLICE induced apoptosis in a cell-free system. Cleavage of caspase zymogens
-
Muzio M, Salvesen GS, Dixit VM: FLICE induced apoptosis in a cell-free system. Cleavage of caspase zymogens. J Biol Chem (1997) 272:2952-2956.
-
(1997)
J Biol Chem
, vol.272
, pp. 2952-2956
-
-
Muzio, M.1
Salvesen, G.S.2
Dixit, V.M.3
-
89
-
-
0029905073
-
Molecular ordering of the Fas-apoptotic pathway: The Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases
-
Srinivasula SM, Ahmad M, Fernandes-Alnemri T, Litwack G, Alnemri ES: Molecular ordering of the Fas-apoptotic pathway: The Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases. Proc Natl Acad Sci USA (1996) 93:14486-14491.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 14486-14491
-
-
Srinivasula, S.M.1
Ahmad, M.2
Fernandes-Alnemri, T.3
Litwack, G.4
Alnemri, E.S.5
-
90
-
-
0029670910
-
CPP32/apopain is a key interleukin 1β converting enzyme-like protease involved in Fas-mediated apoptosis
-
Schlegel J, Peters I, Orrenius S, Miller DK, Thornberry NA, Yamin TT, Nicholson DW: CPP32/apopain is a key interleukin 1β converting enzyme-like protease involved in Fas-mediated apoptosis. J Biol Chem (1996) 271:1841-1844.
-
(1996)
J Biol Chem
, vol.271
, pp. 1841-1844
-
-
Schlegel, J.1
Peters, I.2
Orrenius, S.3
Miller, D.K.4
Thornberry, N.A.5
Yamin, T.T.6
Nicholson, D.W.7
-
91
-
-
0032504575
-
Mitochondria as regulators of apoptosis: Doubt no more
-
Susin SA, Zamzami N, Kroemer G: Mitochondria as regulators of apoptosis: Doubt no more. Biochim Biophys Acta (1998) 1366:151-165.
-
(1998)
Biochim Biophys Acta
, vol.1366
, pp. 151-165
-
-
Susin, S.A.1
Zamzami, N.2
Kroemer, G.3
-
92
-
-
0032575752
-
Mitochondria and apoptosis
-
Green DR, Reed JC: Mitochondria and apoptosis. Science (1998) 281:1309-1312.
-
(1998)
Science
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
93
-
-
0032031920
-
Induction of the mitochondrial permeability transition causes release of the apoptogenic factor cytochrome C
-
Yang JC, Cortopassi GA: Induction of the mitochondrial permeability transition causes release of the apoptogenic factor cytochrome C. Free Radic Biol Med (1998) 24:624-631.
-
(1998)
Free Radic Biol Med
, vol.24
, pp. 624-631
-
-
Yang, J.C.1
Cortopassi, G.A.2
-
94
-
-
0032504717
-
From calcium signaling to cell death: Two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state
-
Ichas F, Mazat JP: From calcium signaling to cell death: Two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state. Biochim Biophys Acta (1998) 1366:33-50.
-
(1998)
Biochim Biophys Acta
, vol.1366
, pp. 33-50
-
-
Ichas, F.1
Mazat, J.P.2
-
95
-
-
0035853721
-
The mitochondrial permeability transition, release of cytochrome C and cell death - Correlation with the duration of pore openings in situ
-
Petronilli V, Penzo D, Scorrano L, Bermardi P, Di Lisa F: The mitochondrial permeability transition, release of cytochrome C and cell death - Correlation with the duration of pore openings in situ. J Biol Chem (2001) 276:12030-12034.
-
(2001)
J Biol Chem
, vol.276
, pp. 12030-12034
-
-
Petronilli, V.1
Penzo, D.2
Scorrano, L.3
Bermardi, P.4
Di Lisa, F.5
-
96
-
-
0032472329
-
Mitochondrial cytochrome C release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
-
Bossy-Wetzel E, Newmeyer DD, Green DR: Mitochondrial cytochrome C release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization. EMBO J (1998) 17:37-49.
-
(1998)
EMBO J
, vol.17
, pp. 37-49
-
-
Bossy-Wetzel, E.1
Newmeyer, D.D.2
Green, D.R.3
-
97
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome C from mitochondria blocked
-
Yang J, Liu X, Bhalla K, Kim CN, Ibrado AM, Cai J, Peng TI, Jones DP, Wang X: Prevention of apoptosis by Bcl-2: Release of cytochrome C from mitochondria blocked. Science (1997) 275:1129-1132.
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
Kim, C.N.4
Ibrado, A.M.5
Cai, J.6
Peng, T.I.7
Jones, D.P.8
Wang, X.9
-
98
-
-
9844257587
-
Inhibition of Bax channel-forming activity by Bcl-2
-
Antonsson B, Conti F, Ciavatta A, Montessuit S, Lewis S, Martinou I, Bernasconi L, Bernard A, Mermod JJ, Mazzei G, Maundrell K et al: Inhibition of Bax channel-forming activity by Bcl-2. Science (1997) 277:370-372.
-
(1997)
Science
, vol.277
, pp. 370-372
-
-
Antonsson, B.1
Conti, F.2
Ciavatta, A.3
Montessuit, S.4
Lewis, S.5
Martinou, I.6
Bernasconi, L.7
Bernard, A.8
Mermod, J.J.9
Mazzei, G.10
Maundrell, K.11
-
99
-
-
0031037897
-
The release of cytochrome C from mitochondria: A primary site for Bcl-2 regulation of apoptosis
-
Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD: The release of cytochrome C from mitochondria: A primary site for Bcl-2 regulation of apoptosis. Science (1997) 275:1132-1136.
-
(1997)
Science
, vol.275
, pp. 1132-1136
-
-
Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
Newmeyer, D.D.4
-
100
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirements for dATP and cytochrome C
-
Liu X, Kim CN, Yang J, Jemmerson R, Wang X: Induction of apoptotic program in cell-free extracts: Requirements for dATP and cytochrome C. Cell (1996) 86:147-157.
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
101
-
-
0032502855
-
Activation of caspases triggered by cytochrome C in vitro
-
Pan G, Humke EW, Dixit VM: Activation of caspases triggered by cytochrome C in vitro. FEBS Lett (1998) 426:151-154.
-
(1998)
FEBS Lett
, vol.426
, pp. 151-154
-
-
Pan, G.1
Humke, E.W.2
Dixit, V.M.3
|