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Volumn 1, Issue 6, 2000, Pages 496-501

Caspase inhibitors improve survival in sepsis: A critical role of the lymphocyte

Author keywords

[No Author keywords available]

Indexed keywords

CASP3 PROTEIN, HUMAN; CASP3 PROTEIN, MOUSE; CASPASE; CASPASE 3; CYSTEINE PROTEINASE INHIBITOR; GAMMA INTERFERON; HOMEODOMAIN PROTEIN; INTERLEUKIN 2; RAG 1 PROTEIN; RAG-1 PROTEIN;

EID: 5944251623     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/82741     Document Type: Article
Times cited : (486)

References (33)
  • 1
    • 0028223194 scopus 로고
    • Sepsis-induced apoptosis of the thymocytes in mice
    • Wang, S. D., Huang, K. J., Lin, Y. S. & Lei, H. Y. Sepsis-induced apoptosis of the thymocytes in mice. J. Immunol. 152, 5014-5021 (1994).
    • (1994) J. Immunol. , vol.152 , pp. 5014-5021
    • Wang, S.D.1    Huang, K.J.2    Lin, Y.S.3    Lei, H.Y.4
  • 2
    • 0029880871 scopus 로고    scopus 로고
    • Differential induction of apoptosis in lymphoid tissue during sepsis: Variation in onset, frequency and nature of the mediators
    • Ayala, A., Herndon, C., Lehman, D. & Chaudry, I. H. Differential induction of apoptosis in lymphoid tissue during sepsis: variation in onset, frequency and nature of the mediators. Blood 87, 4261-4275 (1996).
    • (1996) Blood , vol.87 , pp. 4261-4275
    • Ayala, A.1    Herndon, C.2    Lehman, D.3    Chaudry, I.H.4
  • 3
    • 0030739250 scopus 로고    scopus 로고
    • Apoptosis in lymphoid and parenchymal cells during sepsis: Findings in normal and T- and B-cell deficient mice
    • Hotchkiss, R. S. et al. Apoptosis in lymphoid and parenchymal cells during sepsis: Findings in normal and T- and B-cell deficient mice. Crit. Care Med. 25, 1298-1307 (1997).
    • (1997) Crit. Care Med. , vol.25 , pp. 1298-1307
    • Hotchkiss, R.S.1
  • 4
    • 0032770246 scopus 로고    scopus 로고
    • Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction
    • Hotchkiss, R. S. et al. Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction. Crit. Care Med. 27,1230-1251 (1999).
    • (1999) Crit. Care Med. , vol.27 , pp. 1230-1251
    • Hotchkiss, R.S.1
  • 5
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry, N.A. & Lazebnik, Y. Caspases: enemies within. Science 281, 1312-1316 (1998).
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 6
    • 0032785021 scopus 로고    scopus 로고
    • Caspase structure, proteolytic substrates, and function during apoptotic cell death
    • Nicholson, D.W. Caspase structure, proteolytic substrates, and function during apoptotic cell death. Cell Death Differ. 6, 1028-1042 (1999).
    • (1999) Cell Death Differ. , vol.6 , pp. 1028-1042
    • Nicholson, D.W.1
  • 7
    • 0031892704 scopus 로고
    • Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family
    • Endres, M. et al. Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family. J. Cere. Blood Flow Metabol. 18, 238-247 (1988).
    • (1988) J. Cere. Blood Flow Metabol. , vol.18 , pp. 238-247
    • Endres, M.1
  • 8
    • 0033498191 scopus 로고    scopus 로고
    • Caspase-3-dependent organ apoptosis early after burn injury
    • Fukuzuka, K. et al. Caspase-3-dependent organ apoptosis early after burn injury. Ann. Surg. 229, 851-858 (1999).
    • (1999) Ann. Surg. , vol.229 , pp. 851-858
    • Fukuzuka, K.1
  • 9
    • 0033276621 scopus 로고    scopus 로고
    • Peptidomimetic fluoromethylketone rescues mice from lethal endotoxic shock
    • Grobmeyer, S. R. et al. Peptidomimetic fluoromethylketone rescues mice from lethal endotoxic shock. Mol. Med. 5, 585-594 (1999).
    • (1999) Mol. Med. , vol.5 , pp. 585-594
    • Grobmeyer, S.R.1
  • 10
    • 0033431682 scopus 로고    scopus 로고
    • Prevention of lymphocyte cell death in sepsis improves survival in mice
    • Hotchkiss, R. S. et al. Prevention of lymphocyte cell death in sepsis improves survival in mice. Proc. Natl Acad, Sci. USA 96,14541-14546 (1999).
    • (1999) Proc. Natl Acad, Sci. USA , vol.96 , pp. 14541-14546
    • Hotchkiss, R.S.1
  • 11
    • 0032143986 scopus 로고    scopus 로고
    • Targeted disruption of the mouse caspase 8 gene ablates cell death induction by the TNF receptors, Fas/ApoI and DR3 and is lethal prenatally
    • Varfolomeev, E. E. et al. Targeted disruption of the mouse caspase 8 gene ablates cell death induction by the TNF receptors, Fas/ApoI and DR3 and is lethal prenatally. Immunity 9, 267-276 (1998).
    • (1998) Immunity , vol.9 , pp. 267-276
    • Varfolomeev, E.E.1
  • 12
    • 0032493910 scopus 로고    scopus 로고
    • Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
    • Kuida, K. et al. Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell 94, 325-337 (1998).
    • (1998) Cell , vol.94 , pp. 325-337
    • Kuida, K.1
  • 13
    • 0032493870 scopus 로고    scopus 로고
    • Differential requirement for caspase 9 in apoptotic pathways in vivo
    • Hakem, R. et al. Differential requirement for caspase 9 in apoptotic pathways in vivo. Cell 94, 339-352 (1998).
    • (1998) Cell , vol.94 , pp. 339-352
    • Hakem, R.1
  • 15
    • 0029956641 scopus 로고    scopus 로고
    • Decrease apoptosis in the brain and premature lethality in CPP32-deficient mice
    • Kuida, K et al. Decrease apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature 384, 368-372 (1996).
    • (1996) Nature , vol.384 , pp. 368-372
    • Kuida, K.1
  • 16
    • 15644364847 scopus 로고    scopus 로고
    • Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes
    • Woo, M. et al. Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes. Genes Dev. 12, 806-819 (1998).
    • (1998) Genes Dev. , vol.12 , pp. 806-819
    • Woo, M.1
  • 17
    • 0032484008 scopus 로고    scopus 로고
    • Inhibition of human caspases by peptide-based and macromolecular inhibitors
    • Garcia-Calvo, M. et al. Inhibition of human caspases by peptide-based and macromolecular inhibitors. J. Biol. Chem. 273, 32608-32613 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 32608-32613
    • Garcia-Calvo, M.1
  • 18
    • 0020520054 scopus 로고
    • Evaluation of factors affecting mortality rate after sepsis in a murine cecal ligation and puncture mode
    • Baker, C. C., Chaudry, I. H., Gains, H. O. & Baue, A. E. Evaluation of factors affecting mortality rate after sepsis in a murine cecal ligation and puncture mode. Surgery 94, 331-335 (1983).
    • (1983) Surgery , vol.94 , pp. 331-335
    • Baker, C.C.1    Chaudry, I.H.2    Gains, H.O.3    Baue, A.E.4
  • 19
    • 0034132796 scopus 로고    scopus 로고
    • Comparison of the mortality and inflammatory response of two models of sepsis: Lipopolysaccharide versus cecal ligation and puncture
    • Remick, D. G., Newcomb, D. E., Bolgos, G. L. & Call, D. R. Comparison of the mortality and inflammatory response of two models of sepsis: lipopolysaccharide versus cecal ligation and puncture. Shock 13, 110-116 (2000).
    • (2000) Shock , vol.13 , pp. 110-116
    • Remick, D.G.1    Newcomb, D.E.2    Bolgos, G.L.3    Call, D.R.4
  • 20
    • 0033120115 scopus 로고    scopus 로고
    • Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis
    • Hotchkiss, R. S. et al. Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis. J. Immunol. 162, 4148-4156 (1999).
    • (1999) J. Immunol. , vol.162 , pp. 4148-4156
    • Hotchkiss, R.S.1
  • 21
  • 22
    • 0040298568 scopus 로고    scopus 로고
    • Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
    • Janicke, R. U., Sprengart, M. L., Wati, M. R. & Porter, A. G. Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J. Biol. Chem. 273, 9357-9360 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 9357-9360
    • Janicke, R.U.1    Sprengart, M.L.2    Wati, M.R.3    Porter, A.G.4
  • 26
    • 0032977353 scopus 로고    scopus 로고
    • Neuroprotection by a caspase inhibitor in acute bacterial meningitis
    • Braun, J. S. et al. Neuroprotection by a caspase inhibitor in acute bacterial meningitis. Nature Med. 5, 298-302. (1999).
    • (1999) Nature Med. , vol.5 , pp. 298-302
    • Braun, J.S.1
  • 27
    • 5944235550 scopus 로고    scopus 로고
    • Cytokine signaling- Regulation of the immune system in normal and critically ill states
    • Oberholzer, A., Oberholzer, C. & Moldawer, L. L. Cytokine signaling- regulation of the immune system in normal and critically ill states. Crit Care Med. 28, 53 (2000).
    • (2000) Crit Care Med. , vol.28 , pp. 53
    • Oberholzer, A.1    Oberholzer, C.2    Moldawer, L.L.3
  • 28
  • 29
    • 0022337716 scopus 로고
    • Routine quantitative blood cultures in children with Haemophilus influenzae or Streptococcus pneumoniae bacteremia
    • Bell, L. M., Alpert, G., Campos, J. M. & Plotkin, S.A. Routine quantitative blood cultures in children with Haemophilus influenzae or Streptococcus pneumoniae bacteremia. Pediatrics 76, 901-904 (1985).
    • (1985) Pediatrics , vol.76 , pp. 901-904
    • Bell, L.M.1    Alpert, G.2    Campos, J.M.3    Plotkin, S.A.4
  • 30
    • 0024555884 scopus 로고
    • Enhanced cell-mediated protection against fatal Escherichia coli septicemia induced by treatment with recombinant IL-2
    • Goronzy, J., Weyand, C., Quan, J., Fathman, C. G. & O'Hanley, P. Enhanced cell-mediated protection against fatal Escherichia coli septicemia induced by treatment with recombinant IL-2. J. Immunol. 142, 1134-1138 (1989).
    • (1989) J. Immunol. , vol.142 , pp. 1134-1138
    • Goronzy, J.1    Weyand, C.2    Quan, J.3    Fathman, C.G.4    O'Hanley, P.5
  • 31
    • 0030917203 scopus 로고    scopus 로고
    • Monocyte deactivation in septic patients: Restoration by IFN-γ treatment
    • Docke, W. E. et al. Monocyte deactivation in septic patients: restoration by IFN-γ treatment. Nature Med. 3, 678-681 (1997).
    • (1997) Nature Med. , vol.3 , pp. 678-681
    • Docke, W.E.1
  • 32
    • 0032484008 scopus 로고    scopus 로고
    • Inhibition of human caspases by peptide-based and macromolecular inhibitors
    • Garcia-Calvo, et al. Inhibition of human caspases by peptide-based and macromolecular inhibitors. J. Biol. Chem. 273, 32608-32613 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 32608-32613
    • Garcia-Calvo1
  • 33
    • 0032891964 scopus 로고    scopus 로고
    • Purification and catalytic properties of human caspase family members
    • Garcia-Calvo, M. et al. Purification and catalytic properties of human caspase family members. Cell Death Differ 6, 362-369 (1999).
    • (1999) Cell Death Differ , vol.6 , pp. 362-369
    • Garcia-Calvo, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.