Transgenic mice expressing a dominant negative mutant interleukin-1β converting enzyme show resistance to MPTP neurotoxicity

NeuroReport

Volumn 10, Issue 3, 1999, Pages 635-638

  Klevenyi, Peter ^a   Andreassen, Ole ^a   Ferrante, Robert J ^b,c   Schleicher Jr , John R ^b,c   Friedlander, Robert M ^d   Beal, M Flint ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c DEPARTMENT OF VETERANS AFFAIRS   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Apoptosis; Caspases; Dopamine; MPTP; Parkinson's disease

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; DOPAMINE; INTERLEUKIN 1BETA CONVERTING ENZYME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; DEGENERATIVE DISEASE; IMMUNOREACTIVITY; MOUSE; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; TRANSGENIC MOUSE;

EID: 0033601995     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-199902250-00035     Document Type: Article

References (17)

1. 1. Kosel S. Egensperger R, von Eitzen U et al. Acta Neuropathol 93, 105-108 (1997).
2. 2. Mochizuki H, Goto K, Mori H and Mizuno Y. J Neurol Sci 137, 120-123(1996).
3. 3. Anglade P, Vyas S, Javoy-Agid F et al. Histol Histopathol 12, 25-31 (1997).
4. 4. Mogi M, Harada M, Kondo T et al. Neurosci Lett 215, 137-139 (1996).
5. 5. Friedlander RM and Yuan J. Cell Death & Differ 5, in press (1998).
6. 6. Kuida K, Lippke JA, Ku G et al. Science 267, 2000-2002 (1995).
7. 7. Friedlander RM, Gagliardini V, Hara H et al. J Exp Med 185, 933-940 (1997).
8. 8. Schielke GP, Yang GY, Shivers BD and Betz AL. J Cerebr Blood Flow Metab 18, 180-185 (1988).
9. 9. Hogquist AH, Nett MA, Unaune ER and Chaplin DD. Proc Natl Acad Sci USA 88, 8485-8489 (1991).
10. 10. Miura M, Friedlander RM and Yuan J. Proc Natl Acad Sci USA 92, 8318-8322 (1995).
11. 11. Beal MF, Matson WR, Swartz KJ et al. J Neurochem 55, 1327-1339 (1990).
12. 12. Ferrante RJ, Schulz JB, Kowall NW and Beal MF. Brain Res 753, 157-162 (1997)
13. 13. Bredesen DE. Ann Neurol 38, 839-351 (1995).
14. 14. Tatton NA and Kish SJ. Neuroscience 77, 1037-1048 (1997).
15. 15. Li P, Allen H, Banerjee S et al. Cell 80, 401-411 (1995).
16. 16. Hara H, Fink K, Endres M et al. J Cerebr Blood Flow Metab 17, 370-375 (1997).
17. 17. Friedlander RM, Brown RH, Gagliardini V et al. Nature 388, 31 (1997b).