Induction of the mitochondrial permeability transition causes release of the apoptogenic factor cytochrome C

Free Radical Biology and Medicine

Volumn 24, Issue 4, 1998, Pages 624-631

  Yang, Joy C ^a   Cortopassi, Gino A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apoptosis; Cytochrome c; Free radical; Mitochondria; Permeability transition

Indexed keywords

CYCLOSPORIN A; CYSTEINE PROTEINASE; CYTOCHROME C; FREE RADICAL;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME RELEASE; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; ATRACTYLOSIDE; CALCIUM; CASPASE 3; CASPASES; CYCLOSPORINE; CYSTEINE ENDOPEPTIDASES; CYTOCHROME C GROUP; DEOXYADENINE NUCLEOTIDES; HYDROGEN PEROXIDE; INTRACELLULAR MEMBRANES; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA, LIVER; MITOCHONDRIAL SWELLING; NEUROTOXINS; OXIDANTS; PERMEABILITY; PEROXIDES; TERT-BUTYLHYDROPEROXIDE;

ANIMALIA;

EID: 0032031920     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(97)00367-5     Document Type: Article

References (32)

1. Ellis R. E., Yuan J., Horvitz H. R. Mechanisms and functions of cell death. Ann. Rev. Cell Biol. 7:1991;663-698.
2. Raff M. C. Social controls on cell survival and cell death. Nature. 356:1992;397-400.
3. Steller H. Mechanisms and genes of cellular suicide. Science. 267:1995;1445-1449.
4. Trauth B. C., Klas C., Peters A. M. J., Matzku S., Moller P., Falk W., Debatin K.-M., Krammer P. H. Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science. 245:1989;301-305.
5. Itoh N., Yonehara S., Ishii A., Yonehara M., Mizushima S.-I., Sameshima M., Hase A., Seto Y., Nagata S. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell. 66:1991;233-243.
6. Wong G. H. W., Elwell J. H., Oberley L. W., Goeddel D. V. Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor. Cell. 58:1989;924-931.
7. Hockenbery D. M., Oltvai Z. N., Yin X. M., Milliman C. L., Korsmeyer S. J. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell. 75:1993;241-251.
8. Kane D. J., Sarafian T. A., Anton R., Hahn H., Gralla E. B., Valentine J. S., Oerd T., Bredesen D. E. Bcl-2 inhibition of neural death decreased generation of reactive oxygen species . Science. 262:1993;1274-1277.
9. Wyllie A. H. J. Death in normal and neoplastic cells. Clin. Path. 7:1974;35-42.
10. Alnemri E. S., Livingston D. J., Nicholson D. W., Salvesen G., Thornberry N. A., Wong W. W., Yuan J. Human ICE/CED-3 protease nomenclature. Cell. 87:1996;171.
11. Lazebnik Y. A., Cole S., Cooke C. A., Nelson W. G., Earshaw W. C. Nuclear events of apoptosis in vitro in cell-free mitotic extracts a model system for analysis of the active phase of apoptosis . J. Cell Biol. 123:1993;7-22.
12. Newmeyer D. D., Farschon D. M., Reed J. C. Cell-free apoptosis in Xenopus egg extracts inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria . Cell. 79:1994;353-364.
13. Martin S. J., Newmeyer D. D., Mathias S., Farschon D. M., Wang H.-G., Reed J. C., Kolesnick R. N., Green D. R. Cell-free reconstitution of Fas-, UV radiation- and ceramide-induced apoptosis. EMBO J. 14:1995;5161-5200.
14. Liu X., Kim C. N., Yang J., Jemmerson R., Wang X. Induction of apoptotic program in cell-free extracts requirement for dATP and cytochrome c . Cell. 86:1996;147-157.
15. Crawford D. R., Wang Y., Schools G. P., Kochheiser J., Davies K. J. Down-regulation of mammalian mitochondrial RNAs during oxidative stress. Free. Radic. Biol. Med. 22:1997;551-559.
16. Crawford D. R., Lauzon R. J., Wang Y., Mazurkiewicz J. E., Schools G. P., Davies K. J. 16S mitochondrial ribosomal RNA degradation is associated with apoptosis. Free Radic. Biol. Med. 22:1997;1295-1300.
17. Zoratti M., Szabo I. The mitochondrial permeability transition. Biochim. Biophys. Acta. 1241:1995;139-176.
18. Rickwood D., Wilson M. T., Darley-Usmar V. M. Isolation and characteristics of intact mitochondria. Darley-Usmar V. M., Rickwood D., Wilson M. T. Mitochondria, a practical approach. 1987;1-16 IRL Press, Oxford, Washington, DC.
19. Bernardi P., Vassanelli S., Veronese P., Colonna R., Szabo I., Zoratti M. J. Modulation of the mitochondrial permeability transition pore effect of protons and divalent cations . Biol. Chem. 267:1992;2934-2939.
20. Broekemeier K. M., Dempsey M. E., Pfeiffer D. R. Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria. J. Biol. Chem. 264:1989;7826-7830.
21. Martin S. J., Green D. R. Protease activation during apoptosis death by a thousand cuts? Cell. 82:1995;349-352.
22. Zamzami N., Susin S. A., Marchetti P., Hirsch T., Gomez-Monterrey I., Castedo M., Kroemer G. Mitochondrial control of nuclear apoptosis. J. Exp. Med. 183:1996;1533-1544.
23. Susin A. A., Zamzami N., Castedo M., Hirsch T., Marchetti P., Macho A., Daugas E., Geuskens M., Kroemer G. Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J. Exp. Med. 184:1996;1331-1341.
24. 2+. Biochemistry. 35:1996;8483-8488.
25. Cohen A. R., Hirschhorn S. D., Horowitz A., Rubinstein S. H., Polmar R., Hong D., Martin W. Deoxyadenosine triphosphate as a potentially toxic metabolite in adenosine deaminase deficiency. Proc. Natl. Acad. Sci. USA. 75:1978;472-476.
26. Hirschhorn R. Overview of biochemical abnormalities and molecular genetics of adenosine deaminase deficiency. Pediatr. Res. 33:1993;S35-S41.
27. Markert M. L. Purine nucleoside phosphorylase deficiency. Immunodef. Rev. 3:1991;45-81.
28. Yang J., Liu X., Bhalla K., Kim C. N., Ibrado A. M., Cai J., Peng T. -I., Jones D. P., Wang X. Prevention of apoptosis by Bcl-2 release of cytochrome c from mitochondria blocked . Science. 275:1997;1129-1132.
29. Kluck R. M., Bossy-Wetzel E., Green D. R., Newmeyer D. D. The release of cytochrome c from mitochondria a primary site for Bcl-2 regulation of apoptosis . Science. 275:1997;1132-1136.
30. Pastorino J. G., Snyder J. W., Serroni A., Hoek J. B., Farber J. L. Cyclosporin and carnitine prevent the anoxic death of cultured hepatocytes by inhibiting the mitochondrial permeability transition. J. Biol. Chem. 268:1993;13791-13798.
31. L regulates the membrane potential and volume homeostasis of mitochondria. Cell. 91:1997;627-637.
32. Kantrow S. P., Piantadosi C. A. Release of cytochrome c from liver mitochondria during permeability transition. Biochem. Biophys. Res. Comm. 232:1997;669-671.