FLICE induced apoptosis in a cell-free system. Cleavage of caspase zymogens

Journal of Biological Chemistry

Volumn 272, Issue 5, 1997, Pages 2952-2956

  Muzio, Maria ^a   Salvesen, Guy S ^b   Dixit, Vishva M ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; CASPASE; CYSTEINE PROTEINASE; CYTOKINE RESPONSE MODIFIER A; DNA FRAGMENT; ENZYME PRECURSOR; FAS ANTIGEN; INTERLEUKIN 1BETA CONVERTING ENZYME; SERINE PROTEINASE INHIBITOR; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL FREE SYSTEM; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANTIGENS, CD; ANTIGENS, CD95; APOPTOSIS; CAENORHABDITIS ELEGANS PROTEINS; CASPASE 8; CASPASE 9; CASPASES; CELL NUCLEUS; CELL-FREE SYSTEM; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DNA-BINDING PROTEINS; ENZYME PRECURSORS; HELA CELLS; HELMINTH PROTEINS; HUMANS; OLIGOPEPTIDES; POXVIRIDAE; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECOMBINANT PROTEINS; SERPINS; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; TRANSFECTION; VIRAL PROTEINS;

CAENORHABDITIS ELEGANS; MAMMALIA; POX VIRUS;

EID: 0031018914     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.5.2952     Document Type: Article

References (43)

1. Raff, M. C. (1992) Nature 356, 397-400
2. Steller, H. (1995) Science 267, 1445-1449
3. Chinnaiyan, A. M., and Dixit, V. M. (1996) Curr. Biol. 6, 555-562
4. Yuan, J., Shaham, S., Ledoux, S., Ellis, H. M., and Horvitz, H. R. (1993) Cell 75, 641-652
5. Kumar, S., Kinoshita, M., Noda, M., Copeland, N. G., and Jenkins, N. A. (1994) Genes Dev. 8, 1613-1626
6. Wang, L., Miura, M., Bergeron, L., Zhu, H., and Yuan, J. (1994) Cell 78, 739-750
7. Fernandes-Alnemri, T., Litwack, G., and Alnemri, E. S. (1994) J. Biol. Chem. 269, 30761-30764
8. Nicholson, D. W., Ali, A., Thornberry, N. A., Vaillancourt, J. P., Ding, C. K., Gallant, M., Gareau, Y., Griffin, P. R., Labelle, M., Lazebnik, Y. A., Munday, N. A., Raju, S. M., Smulson, M. E., Yamin, T.-T., Yu, V. L., and Miller, D. K. (1995) Nature 376, 37-43
9. Tewari, M., Quan, L. T., O'Rourke, K., Desnoyers, S., Zeng, Z., Beidler, D. R., Poirier, G. G., Salvesen, G. S., and Dixit, V. M. (1995) Cell 81, 801-809
10. Faucheu, C., Diu, A., Chan, A. W., Blanchet, A. M., Miossec, C., Herve, F., Collard-Dutilleul, V., Gu, Y., Aldape, R. A., Lippke, J. A., Rocher, C., Su, M. S. S., Livingston, D. T., Hercend, T., and Lalanne, J. L. (1995) EMBO J. 14, 1914-1922
11. Kamens, J., Paskind, M., Hugunin, M., Talanian, R. V., Allen, H., Banach, D., Bump, N., Hackett, M., Johnston, C. G., Li, P., Mankovich, J. A., Terranova, M., and Ghayur, T. (1995) J. Biol. Chem. 270, 15250-15256
12. Munday, N. A., Vaillancourt, J. P., Ali, A., Casano, F. J., Miller, D. K., Molineaux, S. M., Yamin, T. T., Yu, V. L., and Nicholson, D. W. (1995) J. Biol. Chem. 270, 15870-15876
13. Fernandes-Alnemri, T., Litwack, G., and Alnemri, E. S. (1995) Cancer Res. 55, 2737-2742
14. Duan, H., Chinnaiyan, A. M., Hudson, P. L., Wing, J. P., He, W., and Dixit, V. M. (1996) J. Biol. Chem. 271, 1621-1625
15. Fernandes-Alnemri, T., Takahashi, A., Armstrong, R., Krebs, J., Fritz, L., Tomaselli, K. J., Wang, L., Yu, Z., Croce, C. M., Salvesen, G., Earnshaw, W. C., Litwack, G., and Alnemri, E. S. (1995) Cancer Res. 55, 6045-6052
16. Lippke, J. A., Gu, Y., Sarnecki, C., Caron, P. R., and Su, M. S.-S. (1996) J. Biol. Chem. 271, 1825-1828
17. Duan, H., Orth, K., Chinnaiyan, A., Poirier, G., Froelich, C. J., He, W.-W., and Dixit, V. M. (1996) J. Biol. Chem. 271, 16720-16724
18. Fernandes-Alnemri T., Armstrong R. C., Kreb J., Srinivasula S. M., Wang L., Bullrich F., Fritz L. C., Trapani J. A., Tomaselli K. J., Litwack G., and Alnemri E. S. (1996) Proc. Natl. Acad. Sci. U. S. A. 98, 7464-7469
19. Potempa, J., Korzus, E., Travis, J. (1994) J. Biol. Chem. 269, 15957-15960
20. Wang, S., Miura, M., Jung, Y., Zhu, H., Gagliardini, V., Shi, L., Greenberg, A. H., and Yuan, J. (1996) J. Biol. Chem. 271, 20580-20587
21. Muzio, M., Chinnaiyan, A. M., Kischkel, F. C., O'Rourke, K., Shevchenko, A., Scaffidi, C., Bretz, J. D., Zhang, M., Ni, J., Gentz, R., Mann, M., Krammer, P. H., Peter, M. E., and Dixit, V. M. (1996) Cell 85, 817-827
22. Boldin M. P., Goncharov T. M., Goltsev Y. V., and Wallach, D. (1996) Cell 85, 803-815
23. Chinnaiyan, A. M., Orth, K., O'Rourke, K., Duan, H., Poirier, G. G., and Dixit, V. M. (1996) J. Biol. Chem. 271, 4573-4576
24. Orth, K., Chinnaiyan, A. M., Garg, M., Froelich, C. J., and Dixit, V. (1996) J. Biol. Chem. 271, 16443-16446
25. Chinnaiyan, A. M., O'Rourke, K., Tewari, M., and Dixit, V. M. (1995) Cell 81, 505-512
26. Boldin, M. P., Varfolomeev, E. E., Panver, I. L., Mett, J. H., Camonis, J. H., and Wallach, D. (1995) J. Biol. Chem. 270, 7795-7798
27. Chinnaiyan, A. M., Tepper, C. G., Seldin, M. F., O'Rourke, K., Kischkel, F. C., Hellbardt, S., Krammer, P. H., Peter, M. E., and Dixit, V. D. (1996) J. Biol. Chem. 271, 4961-4965
28. Enari, M., Hug, H., and Nagata, S. (1995) Nature 375, 78-81
29. Los, M., Van de Craen, M., Penning, L. C., Schenk, H., Westendorp, M., Baeuerle, P. A., Droge, W., Krammer, P. H., Fiers, W., and Schulze-Osthoff, K. (1995) Nature 375, 81-83
30. Tewari, M., and Dixit, V. M. (1995) J. Biol. Chem. 270, 3255-3260
31. Martin, S. J., Newmeyer, D. D., Mathias, S., Farschon, D. M., Wang, H., Reed, J. C., and Green, D. R. (1995) EMBO J. 14, 5191-5200
32. Lazebnik, Y. A., Cole, S., Cooke, C. A., Nelson, W. G., and Earnshaw, W. C. (1993) J. Cell Biol. 123, 7-22
33. Orth, K., O'Rourke, K., Salvesen, G., and Dixit, V. (1996) J. Biol. Chem. 271, 20977-20980
34. Schlegel, J., Peters, I., Orrenius, S., Miller, D. K., Thornberry, N. A., Yamin, T.-T., and Nicholson, D. W. (1996) J. Biol. Chem. 271, 1841-1844
35. Thornberry, N. A., Bull, H. G., Calaycay, J. R., Chapman, K. T., Howard, A. D., Kostura, M. J., Miller, D. K., Molineaux, S. M., Weidner, J. R., Aunins, J., Elliston, K. O., Ayala, J. M., Casano, F. J., Chin, J., Ding, G. J.-F., Egger, L. A., Gaffney, E. P., Limjuco, G., Palyha, O. C., Raju, S. M., Rolando, A. M., Salley, J. P., Yamin, T.-T., Lee, T. D., Shively, J. E., MacCross, M., Mumford, R. A., Schmidt, J. A., and Tocci, M. J. (1992) Nature 356, 768-774
36. Hasegawa, J., Kamada, S., Kamiike, W., Shimizu, S., Imazu, T., Matsuda, H., and Tsujimoto, Y. (1996) Cancer Res. 56, 1713-1718
37. Slee, E. A., Zhu, H., Chow, S. C., MacFarlane, M., Nicholson, D. W., and Cohen G. M. (1996) Biochem. J. 315, 21-24
38. Enari, M., Talanian, R. V., Wong, W. W., and Nagata, S. (1996) Nature 380, 723-726
39. Kuida, K., Lippke, J. A., Ku, G., Harding, M. W., Livingston, D. J., Su, M. S. S., and Flavell, R. A. (1995) Science 267, 2000-2002
40. Darmon, A. J., and Bleackley, C. R. (1996) J. Biol. Chem. 271, 21699-21702
41. Gagliardini, V., Fernandez, P. A., Lee, R. K. K., Hannes, C. A., Drexler, H. C. A., Rotello, R. J., Fishman, M. C., and Yuan, J. (1994) Science 263, 826-828
42. Ray, C. A., Black, R. A., Kronheim, S. R., Greenstreet, T. A., Sleath, P. R., Salvesen, G. S., and Pickup, D. J. (1992) Cell 69, 597-604
43. Travis, J., and Salvesen, G. S. (1983) Annu. Rev. Biochem. 52, 655-709