Rescue from death but not from functional impairment: Caspase inhibition protects dopaminergic cells against 6-hydroxydopamine-induced apoptosis but not against the loss of their terminals

Journal of Neurochemistry

Volumn 77, Issue 1, 2001, Pages 263-273

  Von Coelln, Rainer ^a   Kügler, Sebastian ^a   Bähr, Mathias ^a   Weller, Michael ^a   Dichgans, Johannes ^a   Schulz, Jörg B ^a,b  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b Department of Neurology ^*  (Germany)

Author keywords

6 hydroxydopamine; Apoptosis; Caspases; Gene therapy; Parkinson's disease; X chromosomal inhibitor of apoptosis protein

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CASPASE 3; CASPASE 6; CASPASE 9; CASPASE INHIBITOR; OXIDOPAMINE; TYROSINE 3 MONOOXYGENASE;

APOPTOSIS; ARTICLE; CHROMATIN CONDENSATION; CONTROLLED STUDY; DOPAMINE UPTAKE; DOPAMINERGIC NERVE CELL; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; NEURITE; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; X CHROMOSOME;

ADENOVIRIDAE; AMINO ACID CHLOROMETHYL KETONES; ANIMALS; APOPTOSIS; CASPASES; CELLS, CULTURED; DOPAMINE; ENZYME INHIBITORS; GENE TRANSFER TECHNIQUES; HUMANS; MESENCEPHALON; NEURITES; NEUROBLASTOMA; NEURONS; OXIDOPAMINE; PROTEIN BIOSYNTHESIS; PROTEINS; RATS; TYROSINE 3-MONOOXYGENASE; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 0035085211     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00236.x     Document Type: Article

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