-
1
-
-
0019952999
-
Somatic variants of murine immunoglobulin lambda light chains
-
Bothwell AL, Paskind M, Reth M, Imanishi-Kari T, Rajewsky K, Baltimore D. Somatic variants of murine immunoglobulin lambda light chains. Nature 1982; 298:380-382.
-
(1982)
Nature
, vol.298
, pp. 380-382
-
-
Bothwell, A.L.1
Paskind, M.2
Reth, M.3
Imanishi-Kari, T.4
Rajewsky, K.5
Baltimore, D.6
-
2
-
-
0014943022
-
Variability in the lambda light chain sequences of mouse antibody
-
Weigert MG, Cesari IM, Yonkovich SJ, Cohn M. Variability in the lambda light chain sequences of mouse antibody. Nature 1970; 228:1045-1047.
-
(1970)
Nature
, vol.228
, pp. 1045-1047
-
-
Weigert, M.G.1
Cesari, I.M.2
Yonkovich, S.J.3
Cohn, M.4
-
3
-
-
0020673379
-
The genetic basis of antibody production: A single heavy chain variable region gene encodes all molecules bearing the dominant anti-arsonate idiotype in the strain A mouse
-
Siekevitz M, Huang SY, Gefter ML. The genetic basis of antibody production: A single heavy chain variable region gene encodes all molecules bearing the dominant anti-arsonate idiotype in the strain A mouse. Eur J Immunol 1983; 13:123-132.
-
(1983)
Eur J Immunol
, vol.13
, pp. 123-132
-
-
Siekevitz, M.1
Huang, S.Y.2
Gefter, M.L.3
-
4
-
-
0019424555
-
Somatic mutation of immunoglobulin light-chain variable-region genes
-
Selsing E, Storb U. Somatic mutation of immunoglobulin light-chain variable-region genes. Cell 1981; 25:47-58.
-
(1981)
Cell
, vol.25
, pp. 47-58
-
-
Selsing, E.1
Storb, U.2
-
5
-
-
0025328154
-
Parallel evolution of antibody variable regions by somatic processes: Consecutive shared somatic alterations in VH genes expressed by independently generated hybridomas apparently acquired by point mutation and selection rather than by gene conversion
-
Wysocki LJ, Gefter ML, Margolies MN. Parallel evolution of antibody variable regions by somatic processes: Consecutive shared somatic alterations in VH genes expressed by independently generated hybridomas apparently acquired by point mutation and selection rather than by gene conversion. J Exp Med 1990; 172:315-323.
-
(1990)
J Exp Med
, vol.172
, pp. 315-323
-
-
Wysocki, L.J.1
Gefter, M.L.2
Margolies, M.N.3
-
6
-
-
0022386943
-
Molecular events during maturation of the immune response to oxazolone
-
Berek C, Griffiths GM, Milstein C, Molecular events during maturation of the immune response to oxazolone. Nature 1985; 316:412-418.
-
(1985)
Nature
, vol.316
, pp. 412-418
-
-
Berek, C.1
Griffiths, G.M.2
Milstein, C.3
-
7
-
-
0027305024
-
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells
-
Jacob J, Przylepa J, Miller C, Kelsoe G. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells. J Exp Med 1993; 178:1293-1307.
-
(1993)
J Exp Med
, vol.178
, pp. 1293-1307
-
-
Jacob, J.1
Przylepa, J.2
Miller, C.3
Kelsoe, G.4
-
8
-
-
0028785538
-
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self-tolerance
-
Han S, Zheng B, Dal Porto J, Kelsoe G. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self-tolerance. J Exp Med 1995; 182:1635-1644.
-
(1995)
J Exp Med
, vol.182
, pp. 1635-1644
-
-
Han, S.1
Zheng, B.2
Dal Porto, J.3
Kelsoe, G.4
-
9
-
-
0026515436
-
Accumulation of somatic mutants in the B cell compartment after primary immunization with a T cell-dependent antigen
-
Weiss U, Zoebelein R, Rajewsky K. Accumulation of somatic mutants in the B cell compartment after primary immunization with a T cell-dependent antigen. Eur J Immunol 1992; 22:511-517.
-
(1992)
Eur J Immunol
, vol.22
, pp. 511-517
-
-
Weiss, U.1
Zoebelein, R.2
Rajewsky, K.3
-
10
-
-
0025119989
-
Clustered H chain somatic mutations shared by anti-p-azophenylarsonate antibodies confer enhanced affinity and ablate the cross-reactive idiotype
-
Parhami-Seren B, Wysocki LJ, Margolies MN, Sharon J. Clustered H chain somatic mutations shared by anti-p-azophenylarsonate antibodies confer enhanced affinity and ablate the cross-reactive idiotype. J Immunol 1990; 145:2340-2346.
-
(1990)
J Immunol
, vol.145
, pp. 2340-2346
-
-
Parhami-Seren, B.1
Wysocki, L.J.2
Margolies, M.N.3
Sharon, J.4
-
11
-
-
0027491651
-
Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections
-
Kuppers R, Zhao M, Hansmann ML, Rajewsky K. Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections. EMBO J 1993; 12:4955-4967.
-
(1993)
EMBO J
, vol.12
, pp. 4955-4967
-
-
Kuppers, R.1
Zhao, M.2
Hansmann, M.L.3
Rajewsky, K.4
-
12
-
-
0032006177
-
Bcl-2 obstructs negative selection of autoreactive, hypermutated antibody V regions during memory B cell development
-
Hande S,Notidis E, ManserT. Bcl-2 obstructs negative selection of autoreactive, hypermutated antibody V regions during memory B cell development. Immunity 1998; 8:189-198.
-
(1998)
Immunity
, vol.8
, pp. 189-198
-
-
Hande, S.1
Notidis, E.2
Manser, T.3
-
13
-
-
0025193889
-
Analysis of somatic mutations in kappa transgenes
-
Hackett J, Jr, Rogerson BJ, O'Brien RL, Storb U. Analysis of somatic mutations in kappa transgenes. J Exp Med 1990; 172:131-137.
-
(1990)
J Exp Med
, vol.172
, pp. 131-137
-
-
Hackett J., Jr.1
Rogerson, B.J.2
O'Brien, R.L.3
Storb, U.4
-
14
-
-
0023090516
-
Somatic hypermutation of an immunoglobulin transgene in kappa transgenic mice
-
O'Brien RL, Brinster RL, Storb U. Somatic hypermutation of an immunoglobulin transgene in kappa transgenic mice. Nature 1987; 326:405-409.
-
(1987)
Nature
, vol.326
, pp. 405-409
-
-
O'Brien, R.L.1
Brinster, R.L.2
Storb, U.3
-
15
-
-
0025900034
-
Somatic hypermutation of immunoglobulin kappa may depend on sequences 3′ of C kappa and occurs on passenger transgenes
-
Sharpe MJ, Milstein C, Jarvis JM, Neuberger MS. Somatic hypermutation of immunoglobulin kappa may depend on sequences 3′ of C kappa and occurs on passenger transgenes. EMBO J 1991; 10:2139-2145.
-
(1991)
EMBO J
, vol.10
, pp. 2139-2145
-
-
Sharpe, M.J.1
Milstein, C.2
Jarvis, J.M.3
Neuberger, M.S.4
-
16
-
-
13144259651
-
BCL-6 mutations in normal germinal center B cells: Evidence of somatic hypermutation acting outside Ig loci
-
Pasqualucci L, Migliazza A, Fracchiolla N, William C, Neri A, B aldini L, Chaganti RS, Klein U, Kuppers R, Rajewsky K, Dalla-Favera R. BCL-6 mutations in normal germinal center B cells: Evidence of somatic hypermutation acting outside Ig loci. Proc Natl Acad Sci U S A 1998; 95:11816-11821.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 11816-11821
-
-
Pasqualucci, L.1
Migliazza, A.2
Fracchiolla, N.3
William, C.4
Neri, A.5
Baldini, L.6
Chaganti, R.S.7
Klein, U.8
Kuppers, R.9
Rajewsky, K.10
Dalla-Favera, R.11
-
17
-
-
2642623612
-
Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes
-
Shen HM, Peters A, Baron B, Zhu X, Storb U. Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes. Science 1998; 280:1750-1752.
-
(1998)
Science
, vol.280
, pp. 1750-1752
-
-
Shen, H.M.1
Peters, A.2
Baron, B.3
Zhu, X.4
Storb, U.5
-
18
-
-
0034684682
-
Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction
-
Muschen M, Re D, Jungnickel B, Diehl V, Rajewsky K, Kuppers R. Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction. J Exp Med 2000; 192:1833-1840.
-
(2000)
J Exp Med
, vol.192
, pp. 1833-1840
-
-
Muschen, M.1
Re, D.2
Jungnickel, B.3
Diehl, V.4
Rajewsky, K.5
Kuppers, R.6
-
19
-
-
0032528421
-
Somatic hypermutation of an artificial test substrate within an Ig kappa transgene
-
Klotz EL, Hackett J, Jr., Storb U. Somatic hypermutation of an artificial test substrate within an Ig kappa transgene. J Immunol 1998; 161:782-790.
-
(1998)
J Immunol
, vol.161
, pp. 782-790
-
-
Klotz, E.L.1
Hackett J., Jr.2
Storb, U.3
-
20
-
-
0030063726
-
Somatic hypermutation of immunoglobulin genes is linked to transcription initiation
-
Peters A, Storb U. Somatic hypermutation of immunoglobulin genes is linked to transcription initiation. Immunity 1996; 4:57-65.
-
(1996)
Immunity
, vol.4
, pp. 57-65
-
-
Peters, A.1
Storb, U.2
-
21
-
-
0030821156
-
Insertion of 2 kb of bacteriophage DNA between an immunoglobulin promoter and leader exon stops somatic hypermutation in a kappa transgene
-
Winter DB, Sattar N, Mai JJ, Gearhart PJ. Insertion of 2 kb of bacteriophage DNA between an immunoglobulin promoter and leader exon stops somatic hypermutation in a kappa transgene. Mol Immunol 1997; 34:359-366.
-
(1997)
Mol Immunol
, vol.34
, pp. 359-366
-
-
Winter, D.B.1
Sattar, N.2
Mai, J.J.3
Gearhart, P.J.4
-
22
-
-
0034626802
-
Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes
-
Papavasiliou FN, Schatz DG. Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes. Nature 2000; 408:216-221.
-
(2000)
Nature
, vol.408
, pp. 216-221
-
-
Papavasiliou, F.N.1
Schatz, D.G.2
-
23
-
-
0025148941
-
Distribution of mutations around rearranged heavy-chain antibody variable-region genes
-
Both GW, Taylor L, Pollard JW, Steele EJ. Distribution of mutations around rearranged heavy-chain antibody variable-region genes. Mol Cell Biol 1990; 10:5187-5196.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 5187-5196
-
-
Both, G.W.1
Taylor, L.2
Pollard, J.W.3
Steele, E.J.4
-
24
-
-
0020503988
-
Clusters of point mutations are found exclusively around rearranged antibody variable genes
-
Gearhart PJ, Bogenhagen DF. Clusters of point mutations are found exclusively around rearranged antibody variable genes. Proc Natl Acad Sci U S A 1983; 80:3439-3443.
-
(1983)
Proc Natl Acad Sci U S A
, vol.80
, pp. 3439-3443
-
-
Gearhart, P.J.1
Bogenhagen, D.F.2
-
25
-
-
0028243803
-
The 5′ boundary of somatic hypermutation in a V kappa gene is in the leader intron
-
Rada C, Gonzalez-Fernandez A, Jarvis JM, Milstein C. The 5′ boundary of somatic hypermutation in a V kappa gene is in the leader intron. Eur J Immunol 1994; 24:1453-1457.
-
(1994)
Eur J Immunol
, vol.24
, pp. 1453-1457
-
-
Rada, C.1
Gonzalez-Fernandez, A.2
Jarvis, J.M.3
Milstein, C.4
-
26
-
-
0028125606
-
Mapping the upstream boundary of somatic mutations in rearranged immunoglobulin transgenes and endogenous genes
-
Rogerson BJ. Mapping the upstream boundary of somatic mutations in rearranged immunoglobulin transgenes and endogenous genes. Mol Immunol 1994; 31:83-98.
-
(1994)
Mol Immunol
, vol.31
, pp. 83-98
-
-
Rogerson, B.J.1
-
27
-
-
0025630537
-
Boundaries of somatic mutation in rearranged immunoglobulin genes: 5′ boundary is near the promoter, and 3′ boundary is approximately 1 kb from V(D)J gene
-
Lebecque SG, Gearhart PJ. Boundaries of somatic mutation in rearranged immunoglobulin genes: 5′ boundary is near the promoter, and 3′ boundary is approximately 1 kb from V(D)J gene. J Exp Med 1990; 172:1717-1727.
-
(1990)
J Exp Med
, vol.172
, pp. 1717-1727
-
-
Lebecque, S.G.1
Gearhart, P.J.2
-
28
-
-
0031041632
-
The transcriptional promoter regulates hypermutation of the antibody heavy chain locus
-
Tumas-Brundage K, Manser T. The transcriptional promoter regulates hypermutation of the antibody heavy chain locus. J Exp Med 1997; 185:239-250.
-
(1997)
J Exp Med
, vol.185
, pp. 239-250
-
-
Tumas-Brundage, K.1
Manser, T.2
-
29
-
-
0029067875
-
Targeting of non-Ig sequences in place of the V segment by somatic hypermutation
-
Yelamos J, Klix N, Goyenechea B, Lozano F, Chui YL, Gonzalez Fernandez A, Pannell R, Neuberger MS, Milstein C. Targeting of non-Ig sequences in place of the V segment by somatic hypermutation. Nature 1995; 376:225-229.
-
(1995)
Nature
, vol.376
, pp. 225-229
-
-
Yelamos, J.1
Klix, N.2
Goyenechea, B.3
Lozano, F.4
Chui, Y.L.5
Gonzalez Fernandez, A.6
Pannell, R.7
Neuberger, M.S.8
Milstein, C.9
-
30
-
-
0027510316
-
Mutations of the chloramphenicol acetyl transferase transgene driven by the immunoglobulin promoter and intron enhancer
-
Azuma T, Motoyama N, Fields LE, Loh DY. Mutations of the chloramphenicol acetyl transferase transgene driven by the immunoglobulin promoter and intron enhancer. Int Immunol 1993; 5:121-130.
-
(1993)
Int Immunol
, vol.5
, pp. 121-130
-
-
Azuma, T.1
Motoyama, N.2
Fields, L.E.3
Loh, D.Y.4
-
31
-
-
0032127810
-
Somatic hypermutation in the heavy chain locus correlates with transcription
-
Fukita Y, Jacobs H, Rajewsky K. Somatic hypermutation in the heavy chain locus correlates with transcription. Immunity 1998; 9:105-114.
-
(1998)
Immunity
, vol.9
, pp. 105-114
-
-
Fukita, Y.1
Jacobs, H.2
Rajewsky, K.3
-
32
-
-
0028270307
-
Elements regulating somatic hypermutation of an immunoglobulin kappa gene: Critical role for the intron enhancer/matrix attachment region
-
Betz AG, Milstein C, Gonzalez-Fernandez A, Pannell R, Larson T, Neuberger MS. Elements regulating somatic hypermutation of an immunoglobulin kappa gene: Critical role for the intron enhancer/matrix attachment region. Cell 1994; 77:239-248.
-
(1994)
Cell
, vol.77
, pp. 239-248
-
-
Betz, A.G.1
Milstein, C.2
Gonzalez-Fernandez, A.3
Pannell, R.4
Larson, T.5
Neuberger, M.S.6
-
33
-
-
0032081254
-
Reevaluation of 3′Ekappa function in stage- and lineage-specific rearrangement and somatic hypermutation
-
van der Stoep N, Gorman JR, Alt FW. Reevaluation of 3′Ekappa function in stage- and lineage-specific rearrangement and somatic hypermutation. Immunity 1998; 8:743-750.
-
(1998)
Immunity
, vol.8
, pp. 743-750
-
-
Van der Stoep, N.1
Gorman, J.R.2
Alt, F.W.3
-
34
-
-
0033637358
-
DNA double-strand breaks in immunoglobulin genes undergoing somatic hypermutation
-
Bross L, Fukita Y, McBlane F, Demolliere C, Rajewsky K, Jacobs H. DNA double-strand breaks in immunoglobulin genes undergoing somatic hypermutation. Immunity 2000; 13:589-597.
-
(2000)
Immunity
, vol.13
, pp. 589-597
-
-
Bross, L.1
Fukita, Y.2
McBlane, F.3
Demolliere, C.4
Rajewsky, K.5
Jacobs, H.6
-
35
-
-
0026060520
-
Mutation pattern of immunoglobulin transgenes is compatible with a model of somatic hypermutation in which targeting of the mutator is linked to the direction of DNA replication
-
Rogerson B, Hackett J jr, Peters A, Haasch D, Storb U. Mutation pattern of immunoglobulin transgenes is compatible with a model of somatic hypermutation in which targeting of the mutator is linked to the direction of DNA replication. EMBO J 1991; 10: 4331-4341.
-
(1991)
EMBO J
, vol.10
, pp. 4331-4341
-
-
Rogerson, B.1
Hackett J., Jr.2
Peters, A.3
Haasch, D.4
Storb, U.5
-
36
-
-
0031868081
-
A unifying hypothesis for the molecular mechanism of somatic mutation and gene conversion in rearranged immunoglobulin variable genes
-
Blanden RV, Steele EJ. A unifying hypothesis for the molecular mechanism of somatic mutation and gene conversion in rearranged immunoglobulin variable genes. Immunol Cell Biol 1998; 76:288-293.
-
(1998)
Immunol Cell Biol
, vol.76
, pp. 288-293
-
-
Blanden, R.V.1
Steele, E.J.2
-
37
-
-
0014019617
-
Origin of antibody variation
-
Brenner S, Milstein C. Origin of antibody variation. Nature 1966; 211:242-243.
-
(1966)
Nature
, vol.211
, pp. 242-243
-
-
Brenner, S.1
Milstein, C.2
-
38
-
-
0032541394
-
A hypermutable insert in an immunoglobulin transgene contains hotspots of somatic mutation and sequences predicting highly stable structures in the RNA transcript
-
Storb U, Klotz EL, Hackett J, Kage K, Bozek G, Martin TE. A hypermutable insert in an immunoglobulin transgene contains hotspots of somatic mutation and sequences predicting highly stable structures in the RNA transcript. J Exp Med 1998; 188:689-698.
-
(1998)
J Exp Med
, vol.188
, pp. 689-698
-
-
Storb, U.1
Klotz, E.L.2
Hackett, J.3
Kage, K.4
Bozek, G.5
Martin, T.E.6
-
39
-
-
0000542120
-
The inactivation of the XP-C gene does not affect somatic hypermutation or class switch recombination of immunoglobulin genes
-
Shen HM, Cheo DL, Friedberg E, Storb U. The inactivation of the XP-C gene does not affect somatic hypermutation or class switch recombination of immunoglobulin genes. Mol Immunol 1997; 34:527-533.
-
(1997)
Mol Immunol
, vol.34
, pp. 527-533
-
-
Shen, H.M.1
Cheo, D.L.2
Friedberg, E.3
Storb, U.4
-
40
-
-
0029871507
-
Somatic hypermutation of Ig genes in patients with xeroderma pigmentosum (XP-D)
-
Wagner SD, Elvin JG, Norris P, McGregor JM, Neuberger MS. Somatic hypermutation of Ig genes in patients with xeroderma pigmentosum (XP-D). Int Immunol 1996; 8:701-705.
-
(1996)
Int Immunol
, vol.8
, pp. 701-705
-
-
Wagner, S.D.1
Elvin, J.G.2
Norris, P.3
McGregor, J.M.4
Neuberger, M.S.5
-
41
-
-
0030761761
-
B lymphocytes ofxeroderma pigmentosum or Cockayne syndrome patients with inherited defects in nudeotide excision repair are fully capable of somatic hypermutation of immunoglobulin genes
-
Kim N, Kage K, Matsuda F, Lefranc MP, Storb U. B lymphocytes ofxeroderma pigmentosum or Cockayne syndrome patients with inherited defects in nudeotide excision repair are fully capable of somatic hypermutation of immunoglobulin genes. J Exp Med 1997; 186:413-419.
-
(1997)
J Exp Med
, vol.186
, pp. 413-419
-
-
Kim, N.1
Kage, K.2
Matsuda, F.3
Lefranc, M.P.4
Storb, U.5
-
42
-
-
0032100485
-
The role of DNA repair in somatic hypermutation of immunoglobulin genes
-
Kim N, Storb U. The role of DNA repair in somatic hypermutation of immunoglobulin genes. J Exp Med 1998; 187:1729-1733.
-
(1998)
J Exp Med
, vol.187
, pp. 1729-1733
-
-
Kim, N.1
Storb, U.2
-
43
-
-
0032499751
-
V(D)J hypermutation and DNA mismatch repair: Vexed by fixation
-
Kelsoe G. V(D)J hypermutation and DNA mismatch repair: Vexed by fixation. Proc Natl Acad Sci U S A 1998; 95:6576-6577.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 6576-6577
-
-
Kelsoe, G.1
-
44
-
-
0032555715
-
Somatic hypermutation, transcription, and DNA mismatch repair
-
Wiesendanger M, Scharff MD, Edelmann W. Somatic hypermutation, transcription, and DNA mismatch repair [comment]. Cell 1998; 94:415-418.
-
(1998)
Cell
, vol.94
, pp. 415-418
-
-
Wiesendanger, M.1
Scharff, M.D.2
Edelmann, W.3
-
45
-
-
0032558691
-
DNA repair: Knockouts still mutating after first round
-
Wood RD. DNA repair: Knockouts still mutating after first round. Curr Biol 1998; 8:R757-760.
-
(1998)
Curr Biol
, vol.8
-
-
Wood, R.D.1
-
46
-
-
0033081331
-
Severe attenuation of the B cell immune response in Msh2-deficient mice
-
Vora KA, Tumas-Brundage KM, Lentz VM, Cranston A, Fishel R, Manser T. Severe attenuation of the B cell immune response in Msh2-deficient mice. J Exp Med 1999; 189:471-482.
-
(1999)
J Exp Med
, vol.189
, pp. 471-482
-
-
Vora, K.A.1
Tumas-Brundage, K.M.2
Lentz, V.M.3
Cranston, A.4
Fishel, R.5
Manser, T.6
-
47
-
-
0032555201
-
Tumors of DNA mismatch repair-deficient hosts exhibit dramatic increases in genomic instability
-
Baross-Francis A, Andrew SE, Penney JE, Jirik FR. Tumors of DNA mismatch repair-deficient hosts exhibit dramatic increases in genomic instability. Proc Natl Acad Sci U S A 1998; 95:8739-8743.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 8739-8743
-
-
Baross-Francis, A.1
Andrew, S.E.2
Penney, J.E.3
Jirik, F.R.4
-
48
-
-
0032143823
-
Probing immunoglobulin gene hypermutation with microsatellites suggests a nonreplicative short patch DNA synthesis process
-
Bertocci B, Quint L, Delbos F, Garcia C, Reynaud CA, Weill JC. Probing immunoglobulin gene hypermutation with microsatellites suggests a nonreplicative short patch DNA synthesis process. Immunity 1998; 9:257-265.
-
(1998)
Immunity
, vol.9
, pp. 257-265
-
-
Bertocci, B.1
Quint, L.2
Delbos, F.3
Garcia, C.4
Reynaud, C.A.5
Weill, J.C.6
-
49
-
-
0032127811
-
Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process
-
Frey S, Bertocci B, Delbos F, Quint L, Weill JC, Reynaud CA. Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process. Immunity 1998; 9:127-134.
-
(1998)
Immunity
, vol.9
, pp. 127-134
-
-
Frey, S.1
Bertocci, B.2
Delbos, F.3
Quint, L.4
Weill, J.C.5
Reynaud, C.A.6
-
50
-
-
0034614916
-
Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern
-
Wiesendanger M, Kneitz B, Edelmann W, Scharff MD. Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern. J Exp Med 2000; 191:579-584.
-
(2000)
J Exp Med
, vol.191
, pp. 579-584
-
-
Wiesendanger, M.1
Kneitz, B.2
Edelmann, W.3
Scharff, M.D.4
-
51
-
-
0032101611
-
Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein
-
Phung QH, Winter DB, Cranston A, Tarone RE, Bohr VA, Fishel R, Gearhart PJ. Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein. J Exp Med 1998; 187:1745-1751.
-
(1998)
J Exp Med
, vol.187
, pp. 1745-1751
-
-
Phung, Q.H.1
Winter, D.B.2
Cranston, A.3
Tarone, R.E.4
Bohr, V.A.5
Fishel, R.6
Gearhart, P.J.7
-
52
-
-
0032127804
-
Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting
-
Rada C, Ehrenstein MR, Neuberger MS, Milstein C. Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting. Immunity 1998; 9:135-141.
-
(1998)
Immunity
, vol.9
, pp. 135-141
-
-
Rada, C.1
Ehrenstein, M.R.2
Neuberger, M.S.3
Milstein, C.4
-
53
-
-
0032101017
-
Hypermutation of immunoglobulin genes in memory B cells of DNA repairdeficient mice
-
Jacobs H, Fukita Y, van der Horst GT, de Boer J, Weeda G, Essers J, de Wind N, Engelward BP, Samson L, Verbeek S, de Murcia JM, de Murcia G, te Riele H, Rajewsky K. Hypermutation of immunoglobulin genes in memory B cells of DNA repairdeficient mice. J Exp Med 1998; 187:1735-1743.
-
(1998)
J Exp Med
, vol.187
, pp. 1735-1743
-
-
Jacobs, H.1
Fukita, Y.2
Van der Horst, G.T.3
De Boer, J.4
Weeda, G.5
Essers, J.6
De Wind, N.7
Engelward, B.P.8
Samson, L.9
Verbeek, S.10
De Murcia, J.M.11
De Murcia, G.12
Te Riele, H.13
Rajewsky, K.14
-
54
-
-
0030001287
-
Tracing the development of single memory-lineage B cells in a highly defined immune response
-
Liu AH, Jena PK, Wysocki LJ. Tracing the development of single memory-lineage B cells in a highly defined immune response. J Exp Med 1996; 183: 2053-2063.
-
(1996)
J Exp Med
, vol.183
, pp. 2053-2063
-
-
Liu, A.H.1
Jena, P.K.2
Wysocki, L.J.3
-
55
-
-
0032435650
-
TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line
-
Sale JE, Neuberger MS. TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line. Immunity 1998; 9:859-869.
-
(1998)
Immunity
, vol.9
, pp. 859-869
-
-
Sale, J.E.1
Neuberger, M.S.2
-
56
-
-
0035399804
-
Decreased frequency of somatic hypermutation and impaired affinity maturation but intact germinal center formation in mice expressing antisense RNA to DNA polymerase zeta
-
Diaz M, Verkoczy LK, FlajnikMF, Klinman NR. Decreased frequency of somatic hypermutation and impaired affinity maturation but intact germinal center formation in mice expressing antisense RNA to DNA polymerase zeta. J Immunol 2001; 167:327-335.
-
(2001)
J Immunol
, vol.167
, pp. 327-335
-
-
Diaz, M.1
Verkoczy, L.K.2
Flajnik, M.F.3
Klinman, N.R.4
-
57
-
-
0035005241
-
The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation
-
Zan H, Komori A, Li Z, Cerutti A, Schaffer A, Flajnik MF, Diaz M, Casali P. The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation. Immunity 2001; 14:643-653.
-
(2001)
Immunity
, vol.14
, pp. 643-653
-
-
Zan, H.1
Komori, A.2
Li, Z.3
Cerutti, A.4
Schaffer, A.5
Flajnik, M.F.6
Diaz, M.7
Casali, P.8
-
58
-
-
0035379581
-
Somatic mutation hotspots correlate with DNA polymerase eta error spectrum
-
Rogozin IB, Pavlov YI, Bebenek K, Matsuda T, Kunkel TA. Somatic mutation hotspots correlate with DNA polymerase eta error spectrum. Nat Immunol 2001; 2:530-536.
-
(2001)
Nat Immunol
, vol.2
, pp. 530-536
-
-
Rogozin, I.B.1
Pavlov, Y.I.2
Bebenek, K.3
Matsuda, T.4
Kunkel, T.A.5
-
59
-
-
0035377269
-
DNA polymerase eta is an A-T mutator in somatic hypermutation ofimmunoglobulin variable genes
-
Zeng X, Winter DB, Kasmer C, Kraemer KH, Lehmann AR, Gearhart PJ. DNA polymerase eta is an A-T mutator in somatic hypermutation ofimmunoglobulin variable genes. Nat Immunol 2001; 2:537-541.
-
(2001)
Nat Immunol
, vol.2
, pp. 537-541
-
-
Zeng, X.1
Winter, D.B.2
Kasmer, C.3
Kraemer, K.H.4
Lehmann, A.R.5
Gearhart, P.J.6
-
60
-
-
0343417077
-
Induction of somatic mutation in a human B cell line in vitro
-
Denepoux S, Razanajaona D, Blanchard D, Meffre G, Capra JD, Banchereau J, Lebecque S. Induction of somatic mutation in a human B cell line in vitro. Immunity 1997; 6:35-46.
-
(1997)
Immunity
, vol.6
, pp. 35-46
-
-
Denepoux, S.1
Razanajaona, D.2
Blanchard, D.3
Meffre, G.4
Capra, J.D.5
Banchereau, J.6
Lebecque, S.7
-
61
-
-
0031942085
-
Immunoglobulin hypermutation in cultured cells
-
Green NS, Lin MM, Scharff MD. Immunoglobulin hypermutation in cultured cells. Immunol Rev 1998; 162:77-87.
-
(1998)
Immunol Rev
, vol.162
, pp. 77-87
-
-
Green, N.S.1
Lin, M.M.2
Scharff, M.D.3
-
62
-
-
0033559138
-
Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+ IgD+ B cell line in vitro: Definition of the requirements and modalities of hypermutation
-
Zan H, Cerutti A, Dramitinos P, Schaffer A, Li Z, Casali P. Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+ IgD+ B cell line in vitro: Definition of the requirements and modalities of hypermutation. J Immunol 1999; 162: 3437-3447.
-
(1999)
J Immunol
, vol.162
, pp. 3437-3447
-
-
Zan, H.1
Cerutti, A.2
Dramitinos, P.3
Schaffer, A.4
Li, Z.5
Casali, P.6
-
63
-
-
0027227311
-
Discriminating xintrinsic and antigen-selected mutational hotspots in immunoglobulin V genes
-
Betz AG, Neuberger MS, Milstein C. Discriminating xintrinsic and antigen-selected mutational hotspots in immunoglobulin V genes. Immunol Today 1993; 14:405-411.
-
(1993)
Immunol Today
, vol.14
, pp. 405-411
-
-
Betz, A.G.1
Neuberger, M.S.2
Milstein, C.3
-
64
-
-
0027499308
-
Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: Clustering, polarity, and specific hot spots
-
Betz AG, Rada C, Pannell R, Milstein C, Neuberger MS. Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: Clustering, polarity, and specific hot spots. Proc Nad Acad Sci U S A 1993; 90:2385-2388.
-
(1993)
Proc Nad Acad Sci U S A
, vol.90
, pp. 2385-2388
-
-
Betz, A.G.1
Rada, C.2
Pannell, R.3
Milstein, C.4
Neuberger, M.S.5
-
65
-
-
0026443954
-
Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis
-
Rogozin IB, Kolchanov NA. Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis. Biochim Biophys Acta 1992; 1171:11-18.
-
(1992)
Biochim Biophys Acta
, vol.1171
, pp. 11-18
-
-
Rogozin, I.B.1
Kolchanov, N.A.2
-
66
-
-
0023107028
-
Patterns of somatic mutations in immunoglobulin variable genes
-
Golding GB, Gearhart PJ, Glickman BW. Patterns of somatic mutations in immunoglobulin variable genes. Genetics 1987; 115:169-176.
-
(1987)
Genetics
, vol.115
, pp. 169-176
-
-
Golding, G.B.1
Gearhart, P.J.2
Glickman, B.W.3
-
67
-
-
0023161504
-
Peculiarities of immunoglobulin gene structures as a basis for somatic mutation emergence
-
Kolchanov NA, Solovyov W, Rogozin IB. Peculiarities of immunoglobulin gene structures as a basis for somatic mutation emergence. FEBS Lett 1987; 214: 87-91.
-
(1987)
FEBS Lett
, vol.214
, pp. 87-91
-
-
Kolchanov, N.A.1
Solovyov, W.2
Rogozin, I.B.3
-
69
-
-
0033168638
-
Predicting regional mutability in antibody V genes based solely on di- and trinucleotide sequence composition
-
Shapiro GS, Aviszus K, Ikle D, Wysocki LJ. Predicting regional mutability in antibody V genes based solely on di- and trinucleotide sequence composition. J Immunol 1999; 163:259-268.
-
(1999)
J Immunol
, vol.163
, pp. 259-268
-
-
Shapiro, G.S.1
Aviszus, K.2
Ikle, D.3
Wysocki, L.J.4
-
70
-
-
0029947265
-
Di- and trinudeotide target preferences of somatic mutagenesis in normal and autoreactive B cells
-
Smith DS, Creadon G, Jena PK, Portanova JP, Kotzin BL, Wysocki LJ. Di- and trinudeotide target preferences of somatic mutagenesis in normal and autoreactive B cells. J Immunol 1996; 156:2642-2652.
-
(1996)
J Immunol
, vol.156
, pp. 2642-2652
-
-
Smith, D.S.1
Creadon, G.2
Jena, P.K.3
Portanova, J.P.4
Kotzin, B.L.5
Wysocki, L.J.6
-
71
-
-
0031879159
-
Promoter-associated displacement of hypermutations
-
Wu P, Claflin L. Promoter-associated displacement of hypermutations. Int Immunol 1998; 10:1131-1138.
-
(1998)
Int Immunol
, vol.10
, pp. 1131-1138
-
-
Wu, P.1
Claflin, L.2
-
72
-
-
0031688707
-
Somatic hypermutation of human immunoglobulin heavy chain genes: Targeting of RGYW motifs on both DNA strands
-
Dorner T, Foster SJ, Farner NL, Lipsky PE. Somatic hypermutation of human immunoglobulin heavy chain genes: Targeting of RGYW motifs on both DNA strands. Eur J Immunol 1998; 28:3384-3396.
-
(1998)
Eur J Immunol
, vol.28
, pp. 3384-3396
-
-
Dorner, T.1
Foster, S.J.2
Farner, N.L.3
Lipsky, P.E.4
-
73
-
-
0032585719
-
Somatic hypermutation of VkappaJkappa rearrangements: Targeting of RGYW motifs on both DNA strands and preferential selection of mutated codons within RGYW motifs
-
Foster SJ, Dorner T, Lipsky PE. Somatic hypermutation of VkappaJkappa rearrangements: Targeting of RGYW motifs on both DNA strands and preferential selection of mutated codons within RGYW motifs. Eur J Immuol 1999; 29:4011-4021.
-
(1999)
Eur J Immuol
, vol.29
, pp. 4011-4021
-
-
Foster, S.J.1
Dorner, T.2
Lipsky, P.E.3
-
74
-
-
0031975171
-
Multiple sequences from downstream of the J kappa duster can combine to recruit somatic hypermutation to a heterologous, upstream mutation domain
-
Klix N, Jolly CJ, Davies SL, Bruggemann M, Williams GT, Neuberger MS. Multiple sequences from downstream of the J kappa duster can combine to recruit somatic hypermutation to a heterologous, upstream mutation domain. Eur J Immunol 1998; 28: 317-326.
-
(1998)
Eur J Immunol
, vol.28
, pp. 317-326
-
-
Klix, N.1
Jolly, C.J.2
Davies, S.L.3
Bruggemann, M.4
Williams, G.T.5
Neuberger, M.S.6
-
75
-
-
0031569118
-
Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes
-
Dorner T, Brezinschek HP, Brezinschek RI, Foster SJ, Domiati-Saad R, Lipsky PE. Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes. J Immunol 1997; 158:2779-2789.
-
(1997)
J Immunol
, vol.158
, pp. 2779-2789
-
-
Dorner, T.1
Brezinschek, H.P.2
Brezinschek, R.I.3
Foster, S.J.4
Domiati-Saad, R.5
Lipsky, P.E.6
-
76
-
-
0031764112
-
Strong intrinsic biases towards mutation and conservation of bases in human IgVH genes during somatic hypermutation prevent statistical analysis of antigen selection
-
Dunn-Walters DK, Spencer J. Strong intrinsic biases towards mutation and conservation of bases in human IgVH genes during somatic hypermutation prevent statistical analysis of antigen selection. Immunology 1998; 95:339-345.
-
(1998)
Immunology
, vol.95
, pp. 339-345
-
-
Dunn-Walters, D.K.1
Spencer, J.2
-
77
-
-
0030071749
-
An immunoglobulin mutator that targets G.C base pairs
-
Bachl J, Wabl M. An immunoglobulin mutator that targets G.C base pairs. Proc Nad Acad Sci USA 1996; 93:851-855.
-
(1996)
Proc Nad Acad Sci USA
, vol.93
, pp. 851-855
-
-
Bachl, J.1
Wabl, M.2
-
79
-
-
0030978963
-
Codon bias and plasticity in immunoglobulins
-
Kepler TB. Codon bias and plasticity in immunoglobulins. Mol Biol Evol 1997; 14:637-643.
-
(1997)
Mol Biol Evol
, vol.14
, pp. 637-643
-
-
Kepler, T.B.1
-
81
-
-
0026788298
-
Structural repertoire of the human VH segments
-
Chothia C, Lesk AM, Gherardi E, Tomlinson IM, Walter G, Marks JD, Llewelyn MB, Winter G. Structural repertoire of the human VH segments. J Mol Biol 1992; 227:799-817.
-
(1992)
J Mol Biol
, vol.227
, pp. 799-817
-
-
Chothia, C.1
Lesk, A.M.2
Gherardi, E.3
Tomlinson, I.M.4
Walter, G.5
Marks, J.D.6
Llewelyn, M.B.7
Winter, G.8
-
82
-
-
0029159770
-
The structural repertoire of the human V kappa domain
-
Tomlinson IM, Cox JP, Gherardi E, Lesk AM, Chothia C. The structural repertoire of the human V kappa domain. EMBO J 1995; 14:4628-4638.
-
(1995)
EMBO J
, vol.14
, pp. 4628-4638
-
-
Tomlinson, I.M.1
Cox, J.P.2
Gherardi, E.3
Lesk, A.M.4
Chothia, C.5
-
83
-
-
0030606280
-
Sequence and evolution of the human germline V lambda repertoire
-
Williams SC, Frippiat JP, Tomlinson IM, Ignatovich O, Lefranc MP, Winter G. Sequence and evolution of the human germline V lambda repertoire. J Mol Biol 1996; 264:220-232.
-
(1996)
J Mol Biol
, vol.264
, pp. 220-232
-
-
Williams, S.C.1
Frippiat, J.P.2
Tomlinson, I.M.3
Ignatovich, O.4
Lefranc, M.P.5
Winter, G.6
-
84
-
-
0011974232
-
-
Tomlinson I. "V Base Index." 1998. http://www.mrccpe.cam.ac.uk/imt-doc/restricted/ok.html.
-
(1998)
V Base Index
-
-
Tomlinson, I.1
-
85
-
-
0011970005
-
-
Universidad Nacional Autónoma de México
-
Instituto de Biotecnologia, Universidad Nacional Autónoma de México. "ABG: Germline Gene Directories of Mouse." 1998. http://www.ibt.unam.mx/~almagro/V_mice.html.
-
(1998)
ABG: Germline Gene Directories of Mouse
-
-
-
86
-
-
0032031498
-
Base-specific sequences that bias somatic hypermutation deduced by analysis of out-offrame human IgVH genes
-
Dunn-Walters DK, Dogan A, Boursier L, MacDonald CM, Spencer J. Base-specific sequences that bias somatic hypermutation deduced by analysis of out-offrame human IgVH genes. J Immunol 1998; 160: 2360-2364.
-
(1998)
J Immunol
, vol.160
, pp. 2360-2364
-
-
Dunn-Walters, D.K.1
Dogan, A.2
Boursier, L.3
MacDonald, C.M.4
Spencer, J.5
-
87
-
-
0036169650
-
Effects of sequence and structure on the hypermutability of immunoglobulin genes
-
Michael N, Martin TE, Nicolae D, Kim N, Padjen K, Zhan P, Nguyen H, Pinkert C, Storb U., Effects of sequence and structure on the hypermutability of immunoglobulin genes. Immunity 2002; 16:123-134.
-
(2002)
Immunity
, vol.16
, pp. 123-134
-
-
Michael, N.1
Martin, T.E.2
Nicolae, D.3
Kim, N.4
Padjen, K.5
Zhan, P.6
Nguyen, H.7
Pinkert, C.8
Storb, U.9
-
88
-
-
13144250122
-
Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2
-
Winter DB, Phung QH, Umar A, Baker SM, Tarone RE, Tanaka K, Liskay RM, Kunkel TA, Bohr VA, Gearhart PJ. Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2. Proc Nad Acad Sci U S A 1998; 95:6953-6958.
-
(1998)
Proc Nad Acad Sci U S A
, vol.95
, pp. 6953-6958
-
-
Winter, D.B.1
Phung, Q.H.2
Umar, A.3
Baker, S.M.4
Tarone, R.E.5
Tanaka, K.6
Liskay, R.M.7
Kunkel, T.A.8
Bohr, V.A.9
Gearhart, P.J.10
-
89
-
-
0036499127
-
Evolution of Ig DNA Sequence to target specific base positions within codons for somatic hypermutation
-
Shapiro GS, Aviszus K, Murphy J, Wysocki LJ. Evolution of Ig DNA Sequence to target specific base positions within codons for somatic hypermutation. J Immunol 2002; 168:2302-2306.
-
(2002)
J Immunol
, vol.168
, pp. 2302-2306
-
-
Shapiro, G.S.1
Aviszus, K.2
Murphy, J.3
Wysocki, L.J.4
-
90
-
-
0032848321
-
Targeting and subsequent selection of somatic hypermutations in the human V kappa repertoire
-
Foster SJ, Dorner T, Lipsky PE. Targeting and subsequent selection of somatic hypermutations in the human V kappa repertoire. Eur J Immunol 1999; 29: 3122-3132.
-
(1999)
Eur J Immunol
, vol.29
, pp. 3122-3132
-
-
Foster, S.J.1
Dorner, T.2
Lipsky, P.E.3
-
91
-
-
0031154831
-
Somatic mutation leads to efficient affinity maturation when centrocytes recycle back to centroblasts
-
Oprea M, Perelson AS. Somatic mutation leads to efficient affinity maturation when centrocytes recycle back to centroblasts. J Immunol 1997; 158:5155-5162.
-
(1997)
J Immunol
, vol.158
, pp. 5155-5162
-
-
Oprea, M.1
Perelson, A.S.2
-
92
-
-
0033955009
-
Dynamics of one-pass germinal center models: Implications for affinity maturation
-
Oprea M, van Nimwegen E, Perelson AS. Dynamics of one-pass germinal center models: Implications for affinity maturation. Bull Math Biol 2000; 62:121-153.
-
(2000)
Bull Math Biol
, vol.62
, pp. 121-153
-
-
Oprea, M.1
Van Nimwegen, E.2
Perelson, A.S.3
-
93
-
-
0035822716
-
Toward quantitative simulation of germinal center dynamics: Biological and modeling insights from experimental validation
-
Kleinstein SH, Singh JP. Toward quantitative simulation of germinal center dynamics: Biological and modeling insights from experimental validation. J Theor Biol 2001; 211:253-275.
-
(2001)
J Theor Biol
, vol.211
, pp. 253-275
-
-
Kleinstein, S.H.1
Singh, J.P.2
-
94
-
-
0025817171
-
Somatic hypermutation of the JC intron is markedly reduced in unrearranged kappa and H alleles and is unevenly distributed in rearranged alleles
-
Weber JS, Berry J, Litwin S, Claflin JL. Somatic hypermutation of the JC intron is markedly reduced in unrearranged kappa and H alleles and is unevenly distributed in rearranged alleles. J Immunol 1991; 146:3218-3226.
-
(1991)
J Immunol
, vol.146
, pp. 3218-3226
-
-
Weber, J.S.1
Berry, J.2
Litwin, S.3
Claflin, J.L.4
-
95
-
-
0025911081
-
Position of the rearranged V kappa and its 5′ flanking sequences determines the location of somatic mutations in the J kappa locus
-
Weber JS, Berry J, Manser T, Claflin JL. Position of the rearranged V kappa and its 5′ flanking sequences determines the location of somatic mutations in the J kappa locus. J Immunol 1991; 146:3652-3655.
-
(1991)
J Immunol
, vol.146
, pp. 3652-3655
-
-
Weber, J.S.1
Berry, J.2
Manser, T.3
Claflin, J.L.4
-
96
-
-
0028577994
-
Somatic mutation of immunoglobulin lambda chains: A segment of the major intron hypermutates as much as the complementaritydetermining regions
-
Gonzalez-Fernandez A, Gupta SK, Pannell R, Neuberger MS, Milstein C. Somatic mutation of immunoglobulin lambda chains: A segment of the major intron hypermutates as much as the complementaritydetermining regions. Proc Natl Acad Sci U S A 1994; 91:12614-12618.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 12614-12618
-
-
Gonzalez-Fernandez, A.1
Gupta, S.K.2
Pannell, R.3
Neuberger, M.S.4
Milstein, C.5
-
97
-
-
0028227203
-
Analysis of somatic mutation in five B cell subsets of human tonsil
-
Pascual V, Liu YJ, Magalski A, de Bouteiller O, Banchereau J, Capra JD. Analysis of somatic mutation in five B cell subsets of human tonsil. J Exp Med 1994; 180:329-339.
-
(1994)
J Exp Med
, vol.180
, pp. 329-339
-
-
Pascual, V.1
Liu, Y.J.2
Magalski, A.3
De Bouteiller, O.4
Banchereau, J.5
Capra, J.D.6
-
98
-
-
0027932819
-
Bias in somatic hypermutation of human VH genes
-
Insel RA, Varade WS. Bias in somatic hypermutation of human VH genes. Int Immunol 1994; 6:1437-1443.
-
(1994)
Int Immunol
, vol.6
, pp. 1437-1443
-
-
Insel, R.A.1
Varade, W.S.2
-
99
-
-
0034652015
-
The nucleotide-replacement spectrum under somatic hypermutation exhibits microsequence dependence that is strand-symmetric and distinct from that under germline mutation
-
Cowell LG, Kepler TB. The nucleotide-replacement spectrum under somatic hypermutation exhibits microsequence dependence that is strand-symmetric and distinct from that under germline mutation. J Immunol 2000; 164:1971-1976.
-
(2000)
J Immunol
, vol.164
, pp. 1971-1976
-
-
Cowell, L.G.1
Kepler, T.B.2
-
100
-
-
0033152691
-
Characteristics of sequences around individual nucleotide substitutions in IgVH genes suggest different GC and AT mutators
-
Spencer J, Dunn M, Dunn-Walters DK. Characteristics of sequences around individual nucleotide substitutions in IgVH genes suggest different GC and AT mutators. J Immunol 1999; 162:6596-6601.
-
(1999)
J Immunol
, vol.162
, pp. 6596-6601
-
-
Spencer, J.1
Dunn, M.2
Dunn-Walters, D.K.3
-
101
-
-
0035860310
-
Error rate and specificity of human and murine DNA polymerase eta
-
Matsuda T, Bebenek K, Masutani C, Rogozin IB, Hanaoka F, Kunkel TA. Error rate and specificity of human and murine DNA polymerase eta. J Mol Biol 2001; 312:335-346.
-
(2001)
J Mol Biol
, vol.312
, pp. 335-346
-
-
Matsuda, T.1
Bebenek, K.2
Masutani, C.3
Rogozin, I.B.4
Hanaoka, F.5
Kunkel, T.A.6
-
102
-
-
0026470596
-
What limits affinity maturation of antibodies in Xenopus - The rate of somatic mutation or the ability to select mutants?
-
Wilson M, Hsu E, Marcuz A, Courtet M, Du Pasquier L, Steinberg C. What limits affinity maturation of antibodies in Xenopus - The rate of somatic mutation or the ability to select mutants? EMBO J 1992; 11:4337-4347.
-
(1992)
EMBO J
, vol.11
, pp. 4337-4347
-
-
Wilson, M.1
Hsu, E.2
Marcuz, A.3
Courtet, M.4
Du Pasquier, L.5
Steinberg, C.6
-
103
-
-
0034694086
-
Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG)1 activity
-
Bemark M, Sale JE, Kim HJ, Berek C, Cosgrove RA, Neuberger MS. Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG)1 activity. J Exp Med 2000; 192:1509-1514.
-
(2000)
J Exp Med
, vol.192
, pp. 1509-1514
-
-
Bemark, M.1
Sale, J.E.2
Kim, H.J.3
Berek, C.4
Cosgrove, R.A.5
Neuberger, M.S.6
-
104
-
-
0033521198
-
Somatic insertions and deletions shape the human antibody repertoire
-
de Wildt RM, van Venrooij WJ, Winter G, Hoet RM, Tomlinson IM. Somatic insertions and deletions shape the human antibody repertoire. J Mol Biol 1999; 294:701-710.
-
(1999)
J Mol Biol
, vol.294
, pp. 701-710
-
-
De Wildt, R.M.1
Van Venrooij, W.J.2
Winter, G.3
Hoet, R.M.4
Tomlinson, I.M.5
-
105
-
-
0031983725
-
Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes
-
Wilson PC, de Bouteiller O, Liu YJ, Potter K, Banchereau J, Capra JD, Pascual V. Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes. J Exp Med 1998; 187:59-70.
-
(1998)
J Exp Med
, vol.187
, pp. 59-70
-
-
Wilson, P.C.1
De Bouteiller, O.2
Liu, Y.J.3
Potter, K.4
Banchereau, J.5
Capra, J.D.6
Pascual, V.7
-
106
-
-
0029039723
-
The somatic hypermutation activity of a follicular lymphoma links to large insertions and deletions of immunoglobulin genes
-
Wu HY, Kaartinen M. The somatic hypermutation activity of a follicular lymphoma links to large insertions and deletions of immunoglobulin genes. Scand J Immunol 1995; 42:52-59.
-
(1995)
Scand J Immunol
, vol.42
, pp. 52-59
-
-
Wu, H.Y.1
Kaartinen, M.2
-
107
-
-
0032478071
-
Frequent occurrence of deletions and duplications during somatic hypermutation: Implications for oncogene translocations and heavy chain disease
-
Goossens T, Klein U, Kuppers R. Frequent occurrence of deletions and duplications during somatic hypermutation: Implications for oncogene translocations and heavy chain disease. Proc Nad Acad Sci U S A 1998; 95:2463-2468.
-
(1998)
Proc Nad Acad Sci U S A
, vol.95
, pp. 2463-2468
-
-
Goossens, T.1
Klein, U.2
Kuppers, R.3
-
108
-
-
0030834260
-
Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination
-
Sugawara N, Paques F, Colaiacovo M, Haber JE. Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination. Proc Natl Acad Sci U S A 1997; 94:9214-9219.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 9214-9219
-
-
Sugawara, N.1
Paques, F.2
Colaiacovo, M.3
Haber, J.E.4
-
109
-
-
0034734006
-
Identification of factors interacting with hMSH2 in the fetal liver utilizing the yeast two-hybrid system. In vivo interaction through the C-terminal domains of hEXO1 and hMSH2 and comparative expression analysis
-
Rasmussen LJ, Rasmussen M, Lee B, Rasmussen AK, Wilson DM, Nielsen FC, Bisgaard HC. Identification of factors interacting with hMSH2 in the fetal liver utilizing the yeast two-hybrid system. In vivo interaction through the C-terminal domains of hEXO1 and hMSH2 and comparative expression analysis. Mutat Res 2000; 460:41-52.
-
(2000)
Mutat Res
, vol.460
, pp. 41-52
-
-
Rasmussen, L.J.1
Rasmussen, M.2
Lee, B.3
Rasmussen, A.K.4
Wilson, D.M.5
Nielsen, F.C.6
Bisgaard, H.C.7
-
110
-
-
0035979993
-
The interaction of DNA mismatch repair proteins with human exonuclease I
-
Schmutte C, Sadoff MM, Shim KS, Acharya S, Fishel R. The interaction of DNA mismatch repair proteins with human exonuclease I. J Biol Chem 2001; 276:33011-33018.
-
(2001)
J Biol Chem
, vol.276
, pp. 33011-33018
-
-
Schmutte, C.1
Sadoff, M.M.2
Shim, K.S.3
Acharya, S.4
Fishel, R.5
-
111
-
-
0032532682
-
Human exonuclease I interacts with the mismatch repair protein hMSH2
-
Schmutte C, Marinescu RC, Sadoff MM, Guerrette S, Overhauser J, Fishel R. Human exonuclease I interacts with the mismatch repair protein hMSH2. Cancer Res 1998; 58:4537-4542.
-
(1998)
Cancer Res
, vol.58
, pp. 4537-4542
-
-
Schmutte, C.1
Marinescu, R.C.2
Sadoff, M.M.3
Guerrette, S.4
Overhauser, J.5
Fishel, R.6
-
112
-
-
0030806219
-
Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2
-
Tishkoff DX, Boerger AL, Bertrand P, Filosi N, Gaida GM, Kane MF, Kolodner RD. Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2. Proc Natl Acad Sci U S A 1997; 94:7487-7492.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 7487-7492
-
-
Tishkoff, D.X.1
Boerger, A.L.2
Bertrand, P.3
Filosi, N.4
Gaida, G.M.5
Kane, M.F.6
Kolodner, R.D.7
|