B lymphocytes of xeroderma pigmentosum or cockayne syndrome patients with inherited defects in nucleotide excision repair are fully capable of somatic hypermutation of immunoglobulin genes

Journal of Experimental Medicine

Volumn 186, Issue 3, 1997, Pages 413-419

  Kim, Nayun ^a   Kage, Karen ^a   Matsuda, Fumihiko ^b   Lefranc, Marie Paule ^c   Storb, Ursula ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b KYOTO UNIVERSITY   (Japan)

^c UNIV MONTPELLIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; B LYMPHOCYTE ACTIVATION; COCKAYNE SYNDROME; DNA REPAIR; DNA REPLICATION; EXCISION REPAIR; GENE DUPLICATION; GENE EXPRESSION REGULATION; GENE SWITCHING; HUMAN; HUMAN CELL; IMMUNOGLOBULIN GENE; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; SOMATIC MUTATION; TRANSCRIPTION INITIATION; VIRUS TRANSFORMATION; XERODERMA PIGMENTOSUM;

ADOLESCENT; ADULT; B-LYMPHOCYTES; CELL LINE, TRANSFORMED; CHILD; CHILD, PRESCHOOL; CLONE CELLS; CLONING, MOLECULAR; COCKAYNE SYNDROME; DNA MUTATIONAL ANALYSIS; DNA REPAIR; FEMALE; GENES, IMMUNOGLOBULIN; HERPESVIRUS 4, HUMAN; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MALE; POINT MUTATION; XERODERMA PIGMENTOSUM;

EID: 0030761761     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.186.3.413     Document Type: Article

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