Severe attenuation of the B cell immune response in Msh2-deficient mice

Journal of Experimental Medicine

Volumn 189, Issue 3, 1999, Pages 471-481

  Vora, Kalpit A ^a   Tumas Brundage, Kathleen M ^a   Lentz, Vicky M ^a   Cranston, Aaron ^a   Fishel, Richard ^a   Manser, Tim ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

B cell response; Germinal center; Mismatch repair; Somatic hypermutation

Indexed keywords

CELL PROTEIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; IMMUNOGLOBULIN SUBCLASS; PROTEIN MSH2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; DNA REPAIR; GENE MUTATION; GENETIC ASSOCIATION; GERMINAL CENTER; HUMORAL IMMUNITY; IMMUNE DEFICIENCY; IMMUNOLOGICAL MEMORY; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION;

ANIMALS; ANTIBODIES; APOPTOSIS; B-LYMPHOCYTES; BONE MARROW CELLS; DNA REPAIR; DNA-BINDING PROTEINS; GERMINAL CENTER; HETEROZYGOTE; HOMOZYGOTE; IMMUNE SYSTEM; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN ISOTYPES; LYMPHOCYTE ACTIVATION; MICE; MICE, MUTANT STRAINS; MUTS HOMOLOG 2 PROTEIN; PROTO-ONCOGENE PROTEINS; SPLEEN; T-LYMPHOCYTES;

EID: 0033081331     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.189.3.471     Document Type: Article

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