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Volumn 162, Issue 11, 1999, Pages 6596-6601

Characteristics of sequences around individual nucleotide substitutions in IgV(H) genes suggest different GC and AT mutators

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN;

EID: 0033152691     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (55)

References (26)
  • 1
    • 0026060620 scopus 로고
    • Intraclonal generation of antibody mutants in germinal centres
    • Jacob, J., G. Kelsoe, K. Rajewsky, and U. Weiss. 1991. Intraclonal generation of antibody mutants in germinal centres. Nature 354:389.
    • (1991) Nature , vol.354 , pp. 389
    • Jacob, J.1    Kelsoe, G.2    Rajewsky, K.3    Weiss, U.4
  • 3
    • 0031858512 scopus 로고    scopus 로고
    • Insertions and deletions in hypervariable loops of antibody heavy chains contribute to molecular diversity
    • Ohlin, M., and C. A. Borrebaeck. 1998. Insertions and deletions in hypervariable loops of antibody heavy chains contribute to molecular diversity. Mol. Immunol. 35:233.
    • (1998) Mol. Immunol. , vol.35 , pp. 233
    • Ohlin, M.1    Borrebaeck, C.A.2
  • 5
    • 0031041632 scopus 로고    scopus 로고
    • The transcriptional promoter regulates hypermutation of the antibody heavy chain locus
    • Tumas-Brundage, K., and T. Mauser. 1997. The transcriptional promoter regulates hypermutation of the antibody heavy chain locus. J. Exp. Med. 185:239.
    • (1997) J. Exp. Med. , vol.185 , pp. 239
    • Tumas-Brundage, K.1    Mauser, T.2
  • 7
    • 0031569118 scopus 로고    scopus 로고
    • Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes
    • Dorner, T., H. P. Brezinschek, R. I. Brezinschek, S. J. Foster, R. Domiati-Saad, and P. E. Lipsky. 1997. Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes. J. Immunol. 158:2779.
    • (1997) J. Immunol. , vol.158 , pp. 2779
    • Dorner, T.1    Brezinschek, H.P.2    Brezinschek, R.I.3    Foster, S.J.4    Domiati-Saad, R.5    Lipsky, P.E.6
  • 8
    • 0027227311 scopus 로고
    • Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes
    • Betz, A. G., M. S. Neuberger, and C. Milstein. 1993. Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes. Immunol. Today 14:405.
    • (1993) Immunol. Today , vol.14 , pp. 405
    • Betz, A.G.1    Neuberger, M.S.2    Milstein, C.3
  • 9
    • 0029947265 scopus 로고    scopus 로고
    • Di-and trinucleotide target preferences of somatic mutagenesis in normal and autoreactive B cells
    • Smith, D. S., G. Creadon, P. K. Jena, J. P. Portanova, B. L. Kotzin, and L. J. Wysocki. 1997. Di-and trinucleotide target preferences of somatic mutagenesis in normal and autoreactive B cells. J. Immunol. 156:2642.
    • (1997) J. Immunol. , vol.156 , pp. 2642
    • Smith, D.S.1    Creadon, G.2    Jena, P.K.3    Portanova, J.P.4    Kotzin, B.L.5    Wysocki, L.J.6
  • 10
    • 0027499308 scopus 로고
    • Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: Clustering, polarity, and specific hot spots
    • Betz, A. G., C. Rada, R. Pannell, C. Milstein, and M. S. Neuberger. 1993. Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots. Proc. Natl. Acad. Sci. USA 90:2385.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2385
    • Betz, A.G.1    Rada, C.2    Pannell, R.3    Milstein, C.4    Neuberger, M.S.5
  • 11
    • 0030071749 scopus 로고    scopus 로고
    • An immunoglobulin mutator that targets G.C base pairs
    • Bachl, J., and M. Wabl. 1996. An immunoglobulin mutator that targets G.C base pairs. Proc. Natl. Acad. Sci. USA 93:851.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 851
    • Bachl, J.1    Wabl, M.2
  • 12
  • 15
    • 0031945415 scopus 로고    scopus 로고
    • Analysis of the targeting of the hypermutational machinery and the impact of subsequent selection on the distribution of nucleotide changes in human VHDJH rearrangements
    • Dorner, T., S. J. Foster, H. P. Brezinschek, and P. E. Lipsky. 1998. Analysis of the targeting of the hypermutational machinery and the impact of subsequent selection on the distribution of nucleotide changes in human VHDJH rearrangements. Immunol. Rev. 162:161.
    • (1998) Immunol. Rev. , vol.162 , pp. 161
    • Dorner, T.1    Foster, S.J.2    Brezinschek, H.P.3    Lipsky, P.E.4
  • 16
    • 0026443954 scopus 로고
    • Somatic hypermutagenesis in immunoglobulin genes: Influence of neighbouring base sequences on mutagenesis
    • Rogozin, I. B., and N. A. Kolchanov. 1992. Somatic hypermutagenesis in immunoglobulin genes: influence of neighbouring base sequences on mutagenesis. Biochim. Biophys. Acta. 1171:11.
    • (1992) Biochim. Biophys. Acta. , vol.1171 , pp. 11
    • Rogozin, I.B.1    Kolchanov, N.A.2
  • 17
    • 0030661911 scopus 로고    scopus 로고
    • Hypermutation, diversity, and dissemination of human intestinal lamina propria plasma cells
    • Dunn-Walters, D. K., L. Boursier, and J. Spencer. 1997. Hypermutation, diversity, and dissemination of human intestinal lamina propria plasma cells. Eur. J. Immunol. 27:2959.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 2959
    • Dunn-Walters, D.K.1    Boursier, L.2    Spencer, J.3
  • 18
    • 0031045684 scopus 로고    scopus 로고
    • H genes indicates that ileal lamina propria plasma cells are derived from Peyer's patches
    • H genes indicates that ileal lamina propria plasma cells are derived from Peyer's patches. Eur. J. Immunol. 27:463.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 463
    • Dunn-Walters, D.K.1    Isaacson, P.G.2    Spencer, J.3
  • 20
    • 0029063311 scopus 로고    scopus 로고
    • Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction
    • Brezinschek, H. P., R. I. Brezinschek, and P. E. Lipsky. 1997. Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction. J. Immunol. 155:190.
    • (1997) J. Immunol. , vol.155 , pp. 190
    • Brezinschek, H.P.1    Brezinschek, R.I.2    Lipsky, P.E.3
  • 24
    • 0031894290 scopus 로고    scopus 로고
    • Evolution of somatic hypermutation and gene conversion in adaptive immunity
    • Diaz, M., and M. F. Flajnik. 1998. Evolution of somatic hypermutation and gene conversion in adaptive immunity. Immunol. Rev. 162:13.
    • (1998) Immunol. Rev. , vol.162 , pp. 13
    • Diaz, M.1    Flajnik, M.F.2
  • 25
    • 0032101611 scopus 로고    scopus 로고
    • Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein
    • Phung, Q. H., D. B. Winter, A. Cranston, R. E. Tarone, V. A. Bohr, R. Fishel, and P. J. Gearhart. 1998. Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein. J. Exp. Med. 187:1745.
    • (1998) J. Exp. Med. , vol.187 , pp. 1745
    • Phung, Q.H.1    Winter, D.B.2    Cranston, A.3    Tarone, R.E.4    Bohr, V.A.5    Fishel, R.6    Gearhart, P.J.7
  • 26
    • 0032927459 scopus 로고    scopus 로고
    • Somatic hypermutation and B cell malignancies
    • Spencer, J., and D. K. Dunn-Walters. 1999. Somatic hypermutation and B cell malignancies. J. Pathol. 187:158.
    • (1999) J. Pathol. , vol.187 , pp. 158
    • Spencer, J.1    Dunn-Walters, D.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.