Strong intrinsic biases towards mutation and conservation of bases in human IgV(H) genes during somatic hypermutation prevent statistical analysis of antigen selection

Immunology

Volumn 95, Issue 3, 1998, Pages 339-345

  Dunn Walters, D K ^a   Spencer, J ^a,b  

^a UMDS   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN;

ARTICLE; B LYMPHOCYTE; COMPLEMENTARITY DETERMINING REGION; GENE MUTATION; IMMUNOGLOBULIN VARIABLE REGION; INTESTINE LYMPHATIC TISSUE; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; SOMATIC MUTATION; STATISTICAL ANALYSIS; STOP CODON;

ANTIBODY AFFINITY; BINOMIAL DISTRIBUTION; GENES, IMMUNOGLOBULIN; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; LYMPHOID TISSUE; POINT MUTATION;

EID: 0031764112     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1998.00607.x     Document Type: Article

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