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Volumn 94, Issue 12, 1999, Pages 3997-4010

Regulated genomic instability and neoplasia in the lymphoid lineage

Author keywords

[No Author keywords available]

Indexed keywords

DNA; IMMUNOGLOBULIN; T LYMPHOCYTE RECEPTOR;

EID: 0032785839     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v94.12.3997.424k44_3997_4010     Document Type: Review
Times cited : (102)

References (199)
  • 2
    • 0030272590 scopus 로고    scopus 로고
    • Developmental regulation of V(D)J recombination and lymphocyte differentiation
    • Willerford DM, Swat W, Alt FW: Developmental regulation of V(D)J recombination and lymphocyte differentiation. Curr Opin Genet Dev 6:603, 1996
    • (1996) Curr Opin Genet Dev , vol.6 , pp. 603
    • Willerford, D.M.1    Swat, W.2    Alt, F.W.3
  • 3
    • 0025301095 scopus 로고
    • RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination
    • Oettinger MA, Schatz DG, Gorka C, Baltimore DG: RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. Science 248:1517, 1990
    • (1990) Science , vol.248 , pp. 1517
    • Oettinger, M.A.1    Schatz, D.G.2    Gorka, C.3    Baltimore, D.G.4
  • 5
    • 0028805853 scopus 로고
    • Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps
    • McBlane JF, van Gent DC, Ramsden DA, Romeo C, Cuomo CA, Oettinger MA: Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps. Cell 83:387, 1995
    • (1995) Cell , vol.83 , pp. 387
    • McBlane, J.F.1    Van Gent, D.C.2    Ramsden, D.A.3    Romeo, C.4    Cuomo, C.A.5    Oettinger, M.A.6
  • 6
    • 0029864993 scopus 로고    scopus 로고
    • Intitiation of V(D)J recombination in vitro obeying the 12/23 rule
    • Eastman QM, Leu TM, Schatz DG: Intitiation of V(D)J recombination in vitro obeying the 12/23 rule. Nature 380:85, 1996
    • (1996) Nature , vol.380 , pp. 85
    • Eastman, Q.M.1    Leu, T.M.2    Schatz, D.G.3
  • 7
    • 0030009253 scopus 로고    scopus 로고
    • The Rag-1 and Rag-2 proteins establish the 12/23 rule in V(D)J recombination
    • van Gent DC, Ramsden DA, Gellert M: The Rag-1 and Rag-2 proteins establish the 12/23 rule in V(D)J recombination. Cell 85:107, 1996
    • (1996) Cell , vol.85 , pp. 107
    • Van Gent, D.C.1    Ramsden, D.A.2    Gellert, M.3
  • 8
    • 0032084698 scopus 로고    scopus 로고
    • Assembly of a 12/23 paired signal complex: A critical control point in V(D)J recombination
    • Hiom K, Gellert M: Assembly of a 12/23 paired signal complex: A critical control point in V(D)J recombination. Mol Cell 1:1011, 1998
    • (1998) Mol Cell , vol.1 , pp. 1011
    • Hiom, K.1    Gellert, M.2
  • 14
    • 0029131502 scopus 로고
    • Potential targets for autosomal SCID mutations
    • Taccioli GE, Alt FW: Potential targets for autosomal SCID mutations. Curr Opin Immunol 7:436, 1992
    • (1992) Curr Opin Immunol , vol.7 , pp. 436
    • Taccioli, G.E.1    Alt, F.W.2
  • 15
    • 0025729069 scopus 로고
    • Deletions of immunoglobulin C kappa region characterized by the circular excision products in mouse splenocytes
    • Shimizu T, Iwasato T, Yamagishi H: Deletions of immunoglobulin C kappa region characterized by the circular excision products in mouse splenocytes. J Exp Med 173:1065, 1991
    • (1991) J Exp Med , vol.173 , pp. 1065
    • Shimizu, T.1    Iwasato, T.2    Yamagishi, H.3
  • 16
    • 0029302857 scopus 로고
    • Repair and recombination. How to make ends meet
    • Roth DB, Lindahl T, Gellert M: Repair and recombination. How to make ends meet. Curr Biol 5:496, 1995
    • (1995) Curr Biol , vol.5 , pp. 496
    • Roth, D.B.1    Lindahl, T.2    Gellert, M.3
  • 17
    • 0027397867 scopus 로고
    • The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen
    • Gottlieb TM, Jackson SP: The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen. Cell 72:131, 1993
    • (1993) Cell , vol.72 , pp. 131
    • Gottlieb, T.M.1    Jackson, S.P.2
  • 21
    • 0032167446 scopus 로고    scopus 로고
    • A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination
    • Gao Y, Chaudhuri J, Zhu C, Davidson L, Weaver DT, Alt FW: A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination. Immunity 9:367, 1998
    • (1998) Immunity , vol.9 , pp. 367
    • Gao, Y.1    Chaudhuri, J.2    Zhu, C.3    Davidson, L.4    Weaver, D.T.5    Alt, F.W.6
  • 23
    • 0032438115 scopus 로고    scopus 로고
    • Analysis of variable (diversity) joining recombination in DNAdependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation
    • Bogue MA, Jhappan C, Roth DB: Analysis of variable (diversity) joining recombination in DNAdependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation. Proc Natl Acad Sci USA 95:15559, 1998
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15559
    • Bogue, M.A.1    Jhappan, C.2    Roth, D.B.3
  • 24
    • 0023801238 scopus 로고
    • The defect in murine severe combined immune deficiency: Joining of signal sequences but not coding segments in V(D)J recombination
    • Lieber MR, Hesse JE, Lewis S, Bosma GC, Rosenberg N, Mizuuchi K, Bosma MJ, Gellert M: The defect in murine severe combined immune deficiency: Joining of signal sequences but not coding segments in V(D)J recombination. Cell 55:7, 1988
    • (1988) Cell , vol.55 , pp. 7
    • Lieber, M.R.1    Hesse, J.E.2    Lewis, S.3    Bosma, G.C.4    Rosenberg, N.5    Mizuuchi, K.6    Bosma, M.J.7    Gellert, M.8
  • 26
    • 0028112944 scopus 로고
    • Restoration of x-ray resistance and V(D)J recombination in mutant cells by Ku cDNA
    • Smider V, Rathmell WK, Lieber MR, Chu G: Restoration of x-ray resistance and V(D)J recombination in mutant cells by Ku cDNA. Science 266:288, 1994
    • (1994) Science , vol.266 , pp. 288
    • Smider, V.1    Rathmell, W.K.2    Lieber, M.R.3    Chu, G.4
  • 27
    • 0030858967 scopus 로고    scopus 로고
    • Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination
    • Gu Y, Jin S, Gao Y, Weaver DT, Alt FW: Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination. Proc Natl Acad Sci USA 94:8076, 1997
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8076
    • Gu, Y.1    Jin, S.2    Gao, Y.3    Weaver, D.T.4    Alt, F.W.5
  • 28
    • 0030576534 scopus 로고    scopus 로고
    • Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates
    • Zhu C, Bogue MA, Lim D-S, Hasty P, Roth DB: Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates. Cell 86:379, 1996
    • (1996) Cell , vol.86 , pp. 379
    • Zhu, C.1    Bogue, M.A.2    Lim, D.-S.3    Hasty, P.4    Roth, D.B.5
  • 32
    • 0029585872 scopus 로고
    • The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination
    • Li Z, Otevrel T, Gao Y, Cheng HL, Seed B, Stamato TD, Taccioli GE, Alt FW: The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination. Cell 83: 1079, 1995
    • (1995) Cell , vol.83 , pp. 1079
    • Li, Z.1    Otevrel, T.2    Gao, Y.3    Cheng, H.L.4    Seed, B.5    Stamato, T.D.6    Taccioli, G.E.7    Alt, F.W.8
  • 33
    • 0032185230 scopus 로고    scopus 로고
    • DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes
    • Grawunder U, Zimmer D, Fugmann S, Schwarz K, Lieber MR: DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes. Mol Cell 2:477, 1998
    • (1998) Mol Cell , vol.2 , pp. 477
    • Grawunder, U.1    Zimmer, D.2    Fugmann, S.3    Schwarz, K.4    Lieber, M.R.5
  • 34
    • 0030743386 scopus 로고    scopus 로고
    • Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells
    • Grawunder U, Wilm M, Wu X, Kulesza P, Wilson TE, Mann M, Lieber MR: Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells. Nature 388:492, 1997
    • (1997) Nature , vol.388 , pp. 492
    • Grawunder, U.1    Wilm, M.2    Wu, X.3    Kulesza, P.4    Wilson, T.E.5    Mann, M.6    Lieber, M.R.7
  • 35
    • 0031214080 scopus 로고    scopus 로고
    • Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV
    • Critchlow SE, Bowater RP, Jackson SP: Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV. Curr Biol 7:588, 1997
    • (1997) Curr Biol , vol.7 , pp. 588
    • Critchlow, S.E.1    Bowater, R.P.2    Jackson, S.P.3
  • 38
    • 0033063445 scopus 로고    scopus 로고
    • A striking organization of a large family of human neural cadherin-like cell adhesion genes
    • Wu Q, Maniatis T: A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell 97:779, 1999
    • (1999) Cell , vol.97 , pp. 779
    • Wu, Q.1    Maniatis, T.2
  • 39
    • 0029983727 scopus 로고    scopus 로고
    • Accessibility control of antigen-receptor variable-region gene assembly: Role of cis-acting elements
    • Sleckman BP, Gorman J, Alt FW: Accessibility control of antigen-receptor variable-region gene assembly: Role of cis-acting elements. Annu Rev Immunol 14:459, 1996
    • (1996) Annu Rev Immunol , vol.14 , pp. 459
    • Sleckman, B.P.1    Gorman, J.2    Alt, F.W.3
  • 40
    • 0029894165 scopus 로고    scopus 로고
    • Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro
    • Stanhope-Baker P, Hudson KM, Shaffer AL, Constantinescu A, Schlissel MS: Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro. Cell 85:887, 1996
    • (1996) Cell , vol.85 , pp. 887
    • Stanhope-Baker, P.1    Hudson, K.M.2    Shaffer, A.L.3    Constantinescu, A.4    Schlissel, M.S.5
  • 41
    • 0030273709 scopus 로고    scopus 로고
    • Defect in rearrangement of the most 5′ TCR-Jα following targeted deletion of T early a (TEA): Implications for TCR a locus accessibility
    • Villey I, Caillol D, Selz F, Ferrier P, de Villartay J-P: Defect in rearrangement of the most 5′ TCR-Jα following targeted deletion of T early a (TEA): Implications for TCR a locus accessibility. Immunity 5:331, 1996
    • (1996) Immunity , vol.5 , pp. 331
    • Villey, I.1    Caillol, D.2    Selz, F.3    Ferrier, P.4    De Villartay, J.-P.5
  • 42
    • 0033103012 scopus 로고    scopus 로고
    • Control of V(D)J recombinational acessibility of the Dβ1 gene segment at the TCRβ locus by a germline promoter
    • Whitehurst CJ, Chattopadhyay S, Chen J: Control of V(D)J recombinational acessibility of the Dβ1 gene segment at the TCRβ locus by a germline promoter. Immunity 10:313, 1999
    • (1999) Immunity , vol.10 , pp. 313
    • Whitehurst, C.J.1    Chattopadhyay, S.2    Chen, J.3
  • 43
    • 0030022218 scopus 로고    scopus 로고
    • Antibody class switching
    • Stavnezer J: Antibody class switching. Adv Immunol 61:79, 1996
    • (1996) Adv Immunol , vol.61 , pp. 79
    • Stavnezer, J.1
  • 44
    • 0025345212 scopus 로고
    • Circular DNA is excised by immunoglobulin class switch recombination
    • Iwasato T, Shimizu A, Honjo T, Yamagishi H: Circular DNA is excised by immunoglobulin class switch recombination. Cell 62:143, 1990
    • (1990) Cell , vol.62 , pp. 143
    • Iwasato, T.1    Shimizu, A.2    Honjo, T.3    Yamagishi, H.4
  • 45
    • 0032428658 scopus 로고    scopus 로고
    • Target specificity of immunoglobulin class switch recombination is not determined by nucleotide sequences of S regions
    • Kinoshita K, Tashiro J, Tomita S, Lee CG, Honjo T: Target specificity of immunoglobulin class switch recombination is not determined by nucleotide sequences of S regions. Immunity 9:849, 1998
    • (1998) Immunity , vol.9 , pp. 849
    • Kinoshita, K.1    Tashiro, J.2    Tomita, S.3    Lee, C.G.4    Honjo, T.5
  • 46
    • 0029931447 scopus 로고    scopus 로고
    • Immunoglobulin class switching
    • Stavnezer J: Immunoglobulin class switching. Curr Opin Immunol 8:199, 1996
    • (1996) Curr Opin Immunol , vol.8 , pp. 199
    • Stavnezer, J.1
  • 47
    • 0030273141 scopus 로고    scopus 로고
    • The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching
    • Rolink A, Melchers F, Andersson J: The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching. Immunity 5:319, 1996
    • (1996) Immunity , vol.5 , pp. 319
    • Rolink, A.1    Melchers, F.2    Andersson, J.3
  • 49
    • 0030933777 scopus 로고    scopus 로고
    • The immunoglobulin class switch: Beyond "accessibility."
    • Snapper CM, Marcu KB, Zelazowski P: The immunoglobulin class switch: Beyond "accessibility." Immunity 6:217, 1997
    • (1997) Immunity , vol.6 , pp. 217
    • Snapper, C.M.1    Marcu, K.B.2    Zelazowski, P.3
  • 52
    • 0027969316 scopus 로고
    • Identification of a locus control region in the immunoglobulin heavy-chain locus that deregulates c-myc expression in plasmacytoma and Burkitt's lymphoma cells
    • Madisen L, Groudine M: Identification of a locus control region in the immunoglobulin heavy-chain locus that deregulates c-myc expression in plasmacytoma and Burkitt's lymphoma cells. Genes Dev 8:2212, 1994
    • (1994) Genes Dev , vol.8 , pp. 2212
    • Madisen, L.1    Groudine, M.2
  • 53
    • 0027417869 scopus 로고
    • Shutdown of class switch recombination by deletion of a switch region control element
    • Jung S, Rajewsky K, Radbruch A: Shutdown of class switch recombination by deletion of a switch region control element. Science 259:984, 1993
    • (1993) Science , vol.259 , pp. 984
    • Jung, S.1    Rajewsky, K.2    Radbruch, A.3
  • 54
    • 0027273019 scopus 로고
    • A selective defect in IgG2b switching as a result of targeted mutation of the I gamma 2b promoter and exon
    • Zhang J, Bottaro A, Li S, Stewart V, Alt FW: A selective defect in IgG2b switching as a result of targeted mutation of the I gamma 2b promoter and exon. EMBO J 12:3529, 1993
    • (1993) EMBO J , vol.12 , pp. 3529
    • Zhang, J.1    Bottaro, A.2    Li, S.3    Stewart, V.4    Alt, F.W.5
  • 55
    • 0027952630 scopus 로고
    • S region transcription per se promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process
    • Bottaro A, Lansford R, Xu L, Zhang J, Rothman P, Alt FW: S region transcription per se promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process. EMBO J 13:665, 1994
    • (1994) EMBO J , vol.13 , pp. 665
    • Bottaro, A.1    Lansford, R.2    Xu, L.3    Zhang, J.4    Rothman, P.5    Alt, F.W.6
  • 56
    • 0028968667 scopus 로고
    • Switch transcripts in immunoglobulin class switching
    • Lorenz M, Jung S, Radbruch A: Switch transcripts in immunoglobulin class switching. Science 267:1825, 1995
    • (1995) Science , vol.267 , pp. 1825
    • Lorenz, M.1    Jung, S.2    Radbruch, A.3
  • 57
    • 0032416146 scopus 로고    scopus 로고
    • Processing of switch transcripts is required for targeting of antibody class switch recombination
    • Hein K, Lorenz MG, Siebenkotten G, Petry K, Christine R, Radbruch A: Processing of switch transcripts is required for targeting of antibody class switch recombination. J Exp Med 188:2369, 1998
    • (1998) J Exp Med , vol.188 , pp. 2369
    • Hein, K.1    Lorenz, M.G.2    Siebenkotten, G.3    Petry, K.4    Christine, R.5    Radbruch, A.6
  • 61
    • 0029888843 scopus 로고    scopus 로고
    • The molecular basis of somatic hypermutation of immunoglobulin genes
    • Storb U: The molecular basis of somatic hypermutation of immunoglobulin genes. Curr Opin Immunol 8:206, 1996
    • (1996) Curr Opin Immunol , vol.8 , pp. 206
    • Storb, U.1
  • 62
    • 0031918097 scopus 로고    scopus 로고
    • Progress in understanding the mechanism and consequences of somatic hypermutation
    • Storb U: Progress in understanding the mechanism and consequences of somatic hypermutation. Immunol Rev 162:5, 1998
    • (1998) Immunol Rev , vol.162 , pp. 5
    • Storb, U.1
  • 63
    • 0032100485 scopus 로고    scopus 로고
    • The role of DNA repair in somatic hypermutation of immunoglobulin genes
    • Kim M, Storb U: The role of DNA repair in somatic hypermutation of immunoglobulin genes. J Exp Med 187:1729, 1998
    • (1998) J Exp Med , vol.187 , pp. 1729
    • Kim, M.1    Storb, U.2
  • 64
    • 0032558691 scopus 로고    scopus 로고
    • DNA repair: Knockouts still mutating after first round
    • Wood RD: DNA repair: Knockouts still mutating after first round. Curr Biol 8:R757, 1998
    • (1998) Curr Biol , vol.8
    • Wood, R.D.1
  • 65
    • 0032499751 scopus 로고    scopus 로고
    • V(D)J hypermutation and DNA mismatch repair: Vexed by fixation
    • Kelsoe G: V(D)J hypermutation and DNA mismatch repair: Vexed by fixation. Proc Natl Acad Sci USA 95:6576, 1998
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6576
    • Kelsoe, G.1
  • 67
    • 0032478071 scopus 로고    scopus 로고
    • Frequent occurrence of deletions and duplications during somatic hypermutation: Implications for oncogene translocations and heavy chain disease
    • Goossens T, Klein U, Kuppers R: Frequent occurrence of deletions and duplications during somatic hypermutation: Implications for oncogene translocations and heavy chain disease. Proc Natl Acad Sci USA 95:2463, 1998
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2463
    • Goossens, T.1    Klein, U.2    Kuppers, R.3
  • 69
    • 0032435650 scopus 로고    scopus 로고
    • TdT-accessible breaks are scattered over the immunoglobulin V domain inn a constitutively hypermutating B cell line
    • Sale JE, Neuberger MS: TdT-accessible breaks are scattered over the immunoglobulin V domain inn a constitutively hypermutating B cell line. Immunity 9:859, 1998
    • (1998) Immunity , vol.9 , pp. 859
    • Sale, J.E.1    Neuberger, M.S.2
  • 70
    • 0030483540 scopus 로고    scopus 로고
    • Receptor editing, immune diversification. and self-tolerance
    • Radic MZ, Zouali M: Receptor editing, immune diversification. and self-tolerance. Immunity 5:505, 1996
    • (1996) Immunity , vol.5 , pp. 505
    • Radic, M.Z.1    Zouali, M.2
  • 71
    • 0032442391 scopus 로고    scopus 로고
    • Immune receptor editing: Revise and select
    • Nussenzweig MC: Immune receptor editing: Revise and select. Cell 95:875, 1998
    • (1998) Cell , vol.95 , pp. 875
    • Nussenzweig, M.C.1
  • 72
    • 0029553058 scopus 로고
    • Immunoglobulin heavy chain gene replacement: A mechanism of receptor editing
    • Chen C, Nagy Z, Prak EL, Weigert M: Immunoglobulin heavy chain gene replacement: A mechanism of receptor editing. Immunity 3:747, 1995
    • (1995) Immunity , vol.3 , pp. 747
    • Chen, C.1    Nagy, Z.2    Prak, E.L.3    Weigert, M.4
  • 73
    • 0030997499 scopus 로고    scopus 로고
    • Editing disease-associated autoantibodies
    • Chen C, Prak EL, Weigert M: Editing disease-associated autoantibodies. Immunity 6:97, 1997
    • (1997) Immunity , vol.6 , pp. 97
    • Chen, C.1    Prak, E.L.2    Weigert, M.3
  • 74
    • 0026060620 scopus 로고
    • Intraclonal generation of antibody mutants in germinal centres
    • Jacob J, Kelsoe G, Rajewsky K, Weiss U: Intraclonal generation of antibody mutants in germinal centres. Nature 354:389, 1991
    • (1991) Nature , vol.354 , pp. 389
    • Jacob, J.1    Kelsoe, G.2    Rajewsky, K.3    Weiss, U.4
  • 75
    • 0030938144 scopus 로고    scopus 로고
    • Germinal center development
    • Liu YJ, Arpin C: Germinal center development. Immunol Rev 156:111, 1997
    • (1997) Immunol Rev , vol.156 , pp. 111
    • Liu, Y.J.1    Arpin, C.2
  • 76
    • 0026845876 scopus 로고
    • Maturation and dispersal of B-cell clones during T cell-dependent antibody responses
    • MacLennan IC, Liu YJ, Johnson GD: Maturation and dispersal of B-cell clones during T cell-dependent antibody responses. Immunol Rev 126:143, 1992
    • (1992) Immunol Rev , vol.126 , pp. 143
    • MacLennan, I.C.1    Liu, Y.J.2    Johnson, G.D.3
  • 78
    • 0030460833 scopus 로고    scopus 로고
    • Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells
    • Han S, Zheng B, Schatz DG, Spanopoulou E, Kelsoe G: Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells. Science 274:2094, 1996
    • (1996) Science , vol.274 , pp. 2094
    • Han, S.1    Zheng, B.2    Schatz, D.G.3    Spanopoulou, E.4    Kelsoe, G.5
  • 79
  • 84
    • 0032212784 scopus 로고    scopus 로고
    • RAG reexpression and DNA recombination at T cell receptor loci in peripheral CD4+ T cells
    • McMahan CJ, Fink PJ: RAG reexpression and DNA recombination at T cell receptor loci in peripheral CD4+ T cells. Immunity 9:637, 1998
    • (1998) Immunity , vol.9 , pp. 637
    • McMahan, C.J.1    Fink, P.J.2
  • 85
    • 0028911281 scopus 로고
    • Recurrent chromosomal translocations and fusion genes in leukemia-lymphoma cell lines
    • Drexler HG, MacLeod RAF, Borkhardt A, Janssen JWG: Recurrent chromosomal translocations and fusion genes in leukemia-lymphoma cell lines. Leukemia 9:480, 1995
    • (1995) Leukemia , vol.9 , pp. 480
    • Drexler, H.G.1    MacLeod, R.A.F.2    Borkhardt, A.3    Janssen, J.W.G.4
  • 86
    • 0022972786 scopus 로고
    • A common michanism of chromosomal translocation in T- And B-cell neoplasia
    • Finger LR, Harvey RC, Moore RCA, Showe LC, Croce CM: A common michanism of chromosomal translocation in T- and B-cell neoplasia. Science 234:982, 1986
    • (1986) Science , vol.234 , pp. 982
    • Finger, L.R.1    Harvey, R.C.2    Moore, R.C.A.3    Showe, L.C.4    Croce, C.M.5
  • 87
    • 0026721505 scopus 로고
    • Chromosomal translocations in lymphoid malignancies reveal novel proto-oncogenes
    • Korsmeyer SJ: Chromosomal translocations in lymphoid malignancies reveal novel proto-oncogenes. Annu Rev Immunol 10:785, 1992
    • (1992) Annu Rev Immunol , vol.10 , pp. 785
    • Korsmeyer, S.J.1
  • 88
    • 0026662941 scopus 로고
    • Molecular basis of lymphomagenesis
    • Magrath I: Molecular basis of lymphomagenesis. Cancer Res 52:5529s, 1992
    • (1992) Cancer Res , vol.52
    • Magrath, I.1
  • 89
    • 0027970838 scopus 로고
    • Chromosomal translocations in human cancer
    • Rabbitts TH: Chromosomal translocations in human cancer. Nature 372:143, 1994
    • (1994) Nature , vol.372 , pp. 143
    • Rabbitts, T.H.1
  • 90
    • 0025324784 scopus 로고
    • Chromosomal translocations in lymphoid neoplasia: A reappraisal of the recombinase model
    • Tycko B, Sklar J: Chromosomal translocations in lymphoid neoplasia: A reappraisal of the recombinase model. Cancer Cells 2:1, 1990
    • (1990) Cancer Cells , vol.2 , pp. 1
    • Tycko, B.1    Sklar, J.2
  • 91
    • 0023064529 scopus 로고
    • The role of chromosomal translocations in B- and T-cell neoplasia
    • Showe LC, Croce CM: The role of chromosomal translocations in B- and T-cell neoplasia. Annu Rev Immunol 5:253, 1987
    • (1987) Annu Rev Immunol , vol.5 , pp. 253
    • Showe, L.C.1    Croce, C.M.2
  • 92
    • 0020529709 scopus 로고
    • Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas
    • Adams JM, Gerondakis S, Webb E, Corcoran LM, Cory S: Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas. Proc Natl Acad Sci USA 80:1982, 1983
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 1982
    • Adams, J.M.1    Gerondakis, S.2    Webb, E.3    Corcoran, L.M.4    Cory, S.5
  • 94
    • 0001292985 scopus 로고
    • Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells
    • Taub R, Kirsch I, Morton C, Lenoir G, Swan D, Tronick S, Aaronson S, Leder P: Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells. Proc Natl Acad Sci USA 79:7837, 1982
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 7837
    • Taub, R.1    Kirsch, I.2    Morton, C.3    Lenoir, G.4    Swan, D.5    Tronick, S.6    Aaronson, S.7    Leder, P.8
  • 96
    • 0021266702 scopus 로고
    • A variant translocation places the lambda immunoglobulin genes 3′ to the c-myc oncogene in Burkitt's lymphoma
    • Hollis GF, Mitchell KF, Battey J, Potter H, Taub R, Lenoir GM, Leder P: A variant translocation places the lambda immunoglobulin genes 3′ to the c-myc oncogene in Burkitt's lymphoma. Nature 307:752, 1984
    • (1984) Nature , vol.307 , pp. 752
    • Hollis, G.F.1    Mitchell, K.F.2    Battey, J.3    Potter, H.4    Taub, R.5    Lenoir, G.M.6    Leder, P.7
  • 97
    • 0019951995 scopus 로고
    • Correlation between immunoglobulin light chain expression and variant translocation in Burkitt's lymphoma
    • Lenoir GM, Preud'homme JL, Bernheim A, Berger R: Correlation between immunoglobulin light chain expression and variant translocation in Burkitt's lymphoma. Nature 298:474, 1982
    • (1982) Nature , vol.298 , pp. 474
    • Lenoir, G.M.1    Preud'homme, J.L.2    Bernheim, A.3    Berger, R.4
  • 98
    • 0029686266 scopus 로고    scopus 로고
    • Proteins of the Myc network: Essential regulators of cell growth and differentiation
    • Henriksson M, Luscher B: Proteins of the Myc network: Essential regulators of cell growth and differentiation. Adv Cancer Res 68:109, 1996
    • (1996) Adv Cancer Res , vol.68 , pp. 109
    • Henriksson, M.1    Luscher, B.2
  • 99
    • 0032905924 scopus 로고    scopus 로고
    • c-Myc target genes involved in cell growth, apoptosis, and metabolism
    • Dang CV: c-Myc target genes involved in cell growth, apoptosis, and metabolism. Mol Cell Biol 19:1, 1999
    • (1999) Mol Cell Biol , vol.19 , pp. 1
    • Dang, C.V.1
  • 101
    • 0023022625 scopus 로고
    • The c-myc oncogene perturbs B lymphocyte development in E-mu-myc transgenic mice
    • Langdon WY, Harris AW, Cory S, Adams JM: The c-myc oncogene perturbs B lymphocyte development in E-mu-myc transgenic mice. Cell 47:11, 1986
    • (1986) Cell , vol.47 , pp. 11
    • Langdon, W.Y.1    Harris, A.W.2    Cory, S.3    Adams, J.M.4
  • 102
    • 0022497717 scopus 로고
    • Consequences of widespread deregulation of the c-myc gene in transgenic mice: Multiple neoplasms and normal development
    • Leder A, Pattengale PK, Kuo A, Stewart TA, Leder P: Consequences of widespread deregulation of the c-myc gene in transgenic mice: Multiple neoplasms and normal development. Cell 45:485, 1986
    • (1986) Cell , vol.45 , pp. 485
    • Leder, A.1    Pattengale, P.K.2    Kuo, A.3    Stewart, T.A.4    Leder, P.5
  • 104
    • 0345055662 scopus 로고
    • Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint cluster region near a transcriptionally active locus on chromosome 18
    • Cleary ML, Sklar J: Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint cluster region near a transcriptionally active locus on chromosome 18. Proc Natl Acad Sci USA 82:7439, 1985
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 7439
    • Cleary, M.L.1    Sklar, J.2
  • 105
    • 0022379447 scopus 로고
    • The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining
    • Tsujimoto Y, Gorham J, Cossman J, Jaffe E, Croce CM: The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining. Science 22:1390, 1985
    • (1985) Science , vol.22 , pp. 1390
    • Tsujimoto, Y.1    Gorham, J.2    Cossman, J.3    Jaffe, E.4    Croce, C.M.5
  • 106
    • 0029899181 scopus 로고    scopus 로고
    • Molecular thanatopsis: A discourse on the BCL2 family and cell death
    • Yang E, Korsmeyer SJ: Molecular thanatopsis: A discourse on the BCL2 family and cell death. Blood 88:386, 1996
    • (1996) Blood , vol.88 , pp. 386
    • Yang, E.1    Korsmeyer, S.J.2
  • 107
    • 0023786047 scopus 로고
    • Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
    • Vaux DL, Cory S, Adams JM: Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 335:440, 1988
    • (1988) Nature , vol.335 , pp. 440
    • Vaux, D.L.1    Cory, S.2    Adams, J.M.3
  • 108
    • 0024521441 scopus 로고
    • bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliteration
    • McDonnell TJ, Deane N, Platt FM, Nunez G, Haeger U, McKearn JP, Korsmeyer SJ: bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliteration. Cell 57:79, 1989
    • (1989) Cell , vol.57 , pp. 79
    • McDonnell, T.J.1    Deane, N.2    Platt, F.M.3    Nunez, G.4    Haeger, U.5    McKearn, J.P.6    Korsmeyer, S.J.7
  • 109
    • 0026053958 scopus 로고
    • Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)
    • McDonnell TJ, Korsmeyer SJ: Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18). Nature 349:254, 1991
    • (1991) Nature , vol.349 , pp. 254
    • McDonnell, T.J.1    Korsmeyer, S.J.2
  • 110
    • 0027461627 scopus 로고
    • Eμu-bcl-2 transgene facilitates spontaneous transformation of early pre-B and immunoglobulin secreting cells but not T cells
    • Strasser A, Harris AW, Cory S: Eμu-bcl-2 transgene facilitates spontaneous transformation of early pre-B and immunoglobulin secreting cells but not T cells. Oncogene 8:1, 1993
    • (1993) Oncogene , vol.8 , pp. 1
    • Strasser, A.1    Harris, A.W.2    Cory, S.3
  • 111
    • 0024427427 scopus 로고
    • T cell receptor gene trans-rearrangements: Chimeric γ-δ genes in normal lymphoid tissues
    • Tycko B, Palmer JD, Sklar J: T cell receptor gene trans-rearrangements: Chimeric γ-δ genes in normal lymphoid tissues. Science 245:1242, 1989
    • (1989) Science , vol.245 , pp. 1242
    • Tycko, B.1    Palmer, J.D.2    Sklar, J.3
  • 112
    • 0024987973 scopus 로고
    • Hybrid T cell receptor genes formed by interlocus recombination in normal and Ataxia-telangiectasia lymphocytes
    • Lipkowitz S, Stern M-H, Kirsch IR: Hybrid T cell receptor genes formed by interlocus recombination in normal and Ataxia-telangiectasia lymphocytes. J Exp Med 172:409, 1990
    • (1990) J Exp Med , vol.172 , pp. 409
    • Lipkowitz, S.1    Stern, M.-H.2    Kirsch, I.R.3
  • 113
    • 0026537807 scopus 로고
    • Interallelic V(D)J trans-rearrangement within the beta T cell receptor gene is infrequent and occurs preferentially during attempted D beta to J beta joining
    • Aster JC, Sklar J: Interallelic V(D)J trans-rearrangement within the beta T cell receptor gene is infrequent and occurs preferentially during attempted D beta to J beta joining. J Exp Med 175:1773, 1992
    • (1992) J Exp Med , vol.175 , pp. 1773
    • Aster, J.C.1    Sklar, J.2
  • 114
    • 0025954329 scopus 로고
    • Transrearrangements between antigen receptor genes in normal human lymphoid tissues and in ataxia telangiectasia
    • Kobayashi Y, Tycko B, Soreng AL, Sklar J: Transrearrangements between antigen receptor genes in normal human lymphoid tissues and in ataxia telangiectasia. J Immunol 147:3201, 1991
    • (1991) J Immunol , vol.147 , pp. 3201
    • Kobayashi, Y.1    Tycko, B.2    Soreng, A.L.3    Sklar, J.4
  • 115
    • 0024561067 scopus 로고
    • Consistent breakage between consensus recombinase heptamers of chromosome 9 DNA in a recurrent chromosomal translocation of human T cell leukemia
    • Tycko B, Reynolds TC, Smith SD, Sklar J: Consistent breakage between consensus recombinase heptamers of chromosome 9 DNA in a recurrent chromosomal translocation of human T cell leukemia. J Exp Med 169:369, 1989
    • (1989) J Exp Med , vol.169 , pp. 369
    • Tycko, B.1    Reynolds, T.C.2    Smith, S.D.3    Sklar, J.4
  • 117
    • 0023988146 scopus 로고
    • Different regions of the immunoglobulin heavy-chain locus are involved in chromosomal translocations in distinct pathogenetic forms of Burkitt lymphoma
    • Neri A, Barriga F, Knowles DM, Magrath IT, Dalla-Favera R: Different regions of the immunoglobulin heavy-chain locus are involved in chromosomal translocations in distinct pathogenetic forms of Burkitt lymphoma. Proc Natl Acad Sci USA 85:2748, 1988
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 2748
    • Neri, A.1    Barriga, F.2    Knowles, D.M.3    Magrath, I.T.4    Dalla-Favera, R.5
  • 119
    • 0027506314 scopus 로고
    • Mechanism of the chromosomal translocation t(14:18) in lymphoma: Detection of a 45-Kd breakpoint binding protein
    • Jaeger U, Purtscher B, Delle Karth G, Knap S, Mannhalter C, Lechner K: Mechanism of the chromosomal translocation t(14:18) in lymphoma: Detection of a 45-Kd breakpoint binding protein. Blood 81:1833, 1993
    • (1993) Blood , vol.81 , pp. 1833
    • Jaeger, U.1    Purtscher, B.2    Delle Karth, G.3    Knap, S.4    Mannhalter, C.5    Lechner, K.6
  • 120
    • 0032551829 scopus 로고    scopus 로고
    • Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system
    • Agrawal A, Eastman QM, Schatz DG: Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system. Nature 394:744, 1998
    • (1998) Nature , vol.394 , pp. 744
    • Agrawal, A.1    Eastman, Q.M.2    Schatz, D.G.3
  • 121
    • 0032555758 scopus 로고    scopus 로고
    • DNA transposition by the RAG1 and RAG2 proteins: A possible source of oncogenic translocations
    • Hiom K, Melek M, Gellert M: DNA transposition by the RAG1 and RAG2 proteins: A possible source of oncogenic translocations. Cell 94:463, 1998
    • (1998) Cell , vol.94 , pp. 463
    • Hiom, K.1    Melek, M.2    Gellert, M.3
  • 122
    • 0026720409 scopus 로고
    • Molecular epidemiology of Burkitt's lymphoma from South America: Differences in breakpoint location and Epstein-Barr virus association from tumors in other world regions
    • Gutierrez MI, Bhatia K, Barriga F, Diez B, Muriel FS, de Andreas ML, Epelman S, Risueno C, Magrath IT: Molecular epidemiology of Burkitt's lymphoma from South America: Differences in breakpoint location and Epstein-Barr virus association from tumors in other world regions. Blood 79:3261, 1992
    • (1992) Blood , vol.79 , pp. 3261
    • Gutierrez, M.I.1    Bhatia, K.2    Barriga, F.3    Diez, B.4    Muriel, F.S.5    De Andreas, M.L.6    Epelman, S.7    Risueno, C.8    Magrath, I.T.9
  • 124
    • 0020985675 scopus 로고
    • Interchromosomal recombination of the cellular oncogene c-myc with the immunoglobulin heavy chain locus in murine plasmacytomas is a reciprocal exchange
    • Cory S, Gerondakis S, Adams JM: Interchromosomal recombination of the cellular oncogene c-myc with the immunoglobulin heavy chain locus in murine plasmacytomas is a reciprocal exchange. EMBO J 2:697, 1983
    • (1983) EMBO J , vol.2 , pp. 697
    • Cory, S.1    Gerondakis, S.2    Adams, J.M.3
  • 125
    • 0021183016 scopus 로고
    • Translocation of the myc cellular oncogene to the immunoglobulin heavy chain locus in murine plasmacytomas is an imprecise reciprocal exchange
    • Gerondakis S, Cory S, Adams JM: Translocation of the myc cellular oncogene to the immunoglobulin heavy chain locus in murine plasmacytomas is an imprecise reciprocal exchange. Cell 36:973, 1984
    • (1984) Cell , vol.36 , pp. 973
    • Gerondakis, S.1    Cory, S.2    Adams, J.M.3
  • 126
    • 0031001374 scopus 로고    scopus 로고
    • Experimental plasmacytomagenesis in mice
    • Potter M: Experimental plasmacytomagenesis in mice. Hematol Oncol Clin North Am 11:323, 1997
    • (1997) Hematol Oncol Clin North Am , vol.11 , pp. 323
    • Potter, M.1
  • 127
    • 0032971585 scopus 로고    scopus 로고
    • Insertion of excised IgH switch sequences causes overexpression of cyclin D1 in a myeloma tumor cell
    • Gabrea A, Bergsagel PL, Chesi M, Shou Y, Kuehl WM: Insertion of excised IgH switch sequences causes overexpression of cyclin D1 in a myeloma tumor cell. Mol Cell 3:119, 1999
    • (1999) Mol Cell , vol.3 , pp. 119
    • Gabrea, A.1    Bergsagel, P.L.2    Chesi, M.3    Shou, Y.4    Kuehl, W.M.5
  • 129
    • 0021279267 scopus 로고
    • Effect of somatic mutation within translocated c-myc genes in Burkitt's lymphoma
    • Rabbitts TH, Forster A, Hamlyn P, Baer R: Effect of somatic mutation within translocated c-myc genes in Burkitt's lymphoma. Nature 309:592, 1984
    • (1984) Nature , vol.309 , pp. 592
    • Rabbitts, T.H.1    Forster, A.2    Hamlyn, P.3    Baer, R.4
  • 131
    • 2642623612 scopus 로고    scopus 로고
    • Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes
    • Shen HM, Peters A, Baron B, Zhu X, Storb U: Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes. Science 280:1750, 1998
    • (1998) Science , vol.280 , pp. 1750
    • Shen, H.M.1    Peters, A.2    Baron, B.3    Zhu, X.4    Storb, U.5
  • 134
  • 136
    • 0022472723 scopus 로고
    • Mortality and cancer incidence in 263 patients with ataxia-telangiectasia
    • Morrell D, Cromartie E, Swift M: Mortality and cancer incidence in 263 patients with ataxia-telangiectasia. J Natl Cancer Inst 77:89, 1986
    • (1986) J Natl Cancer Inst , vol.77 , pp. 89
    • Morrell, D.1    Cromartie, E.2    Swift, M.3
  • 137
  • 144
    • 0033566329 scopus 로고    scopus 로고
    • Somatic ATM mutations indicate a pathogenic role of ATM in B-cell chronic lymphocytic leukemia
    • Schaffner C, Stilgenbauer S, Rappold GA, Dohner H, Lichter P: Somatic ATM mutations indicate a pathogenic role of ATM in B-cell chronic lymphocytic leukemia. Blood 94:748, 1999
    • (1999) Blood , vol.94 , pp. 748
    • Schaffner, C.1    Stilgenbauer, S.2    Rappold, G.A.3    Dohner, H.4    Lichter, P.5
  • 146
    • 0027476890 scopus 로고
    • Repair and misrepair of site-specific DNA double-strand breaks by human cell extracts
    • Ganesh A, North P, Thacker J: Repair and misrepair of site-specific DNA double-strand breaks by human cell extracts. Mutat Res 299:251, 1993
    • (1993) Mutat Res , vol.299 , pp. 251
    • Ganesh, A.1    North, P.2    Thacker, J.3
  • 147
    • 0027304013 scopus 로고
    • V(D)J recombination in ataxia telangiectasia. Bloom's syndrome, and a DNA ligase I-associated immunodeficiency disorder
    • Hsieh CL, Arlett CF, Lieber MR: V(D)J recombination in ataxia telangiectasia. Bloom's syndrome, and a DNA ligase I-associated immunodeficiency disorder. J Biol Chem 268:20105, 1993
    • (1993) J Biol Chem , vol.268 , pp. 20105
    • Hsieh, C.L.1    Arlett, C.F.2    Lieber, M.R.3
  • 149
    • 0032484084 scopus 로고    scopus 로고
    • Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
    • Matsuoka S, Huang M, Elledge SJ: Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science 282:1893, 1998
    • (1998) Science , vol.282 , pp. 1893
    • Matsuoka, S.1    Huang, M.2    Elledge, S.J.3
  • 156
    • 0032076248 scopus 로고    scopus 로고
    • The hMre 11/hRad50 protein complex and Nijmegen breakage syndrome: Linkage of double-strand break repair Io the cellular DNA damage response
    • Carney JP, Mase RS, Olivares H, Davis EM, Le Beau M, Yates JRI, Hays L, Morgan WF, Petrini JHJ: The hMre 11/hRad50 protein complex and Nijmegen breakage syndrome: Linkage of double-strand break repair Io the cellular DNA damage response. Cell 93:477, 1998
    • (1998) Cell , vol.93 , pp. 477
    • Carney, J.P.1    Mase, R.S.2    Olivares, H.3    Davis, E.M.4    Le Beau, M.5    Yates, J.R.I.6    Hays, L.7    Morgan, W.F.8    Petrini, J.H.J.9
  • 157
    • 0032562595 scopus 로고    scopus 로고
    • In situ visualization of DNA double-strand break repair in human fibroblasts
    • Nelms BE, Maser RS, MacKay JF, Lagally MG, Petrini JH: In situ visualization of DNA double-strand break repair in human fibroblasts. Science 280:590, 1998
    • (1998) Science , vol.280 , pp. 590
    • Nelms, B.E.1    Maser, R.S.2    MacKay, J.F.3    Lagally, M.G.4    Petrini, J.H.5
  • 158
    • 0032567041 scopus 로고    scopus 로고
    • The many interfaces of Mre11
    • Haber JE: The many interfaces of Mre11. Cell 95:583, 1998
    • (1998) Cell , vol.95 , pp. 583
    • Haber, J.E.1
  • 159
    • 0032085295 scopus 로고    scopus 로고
    • The 3′ to 5′ exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks
    • Paull TT, Gellen M: The 3′ to 5′ exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks. Mol Cell 1:969, 1998
    • (1998) Mol Cell , vol.1 , pp. 969
    • Paull, T.T.1    Gellen, M.2
  • 160
    • 0033563229 scopus 로고    scopus 로고
    • Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex
    • Paull TT, Gellert M: Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex. Genes Dev 13:1276, 1999
    • (1999) Genes Dev , vol.13 , pp. 1276
    • Paull, T.T.1    Gellert, M.2
  • 163
    • 0031052108 scopus 로고    scopus 로고
    • Bloom's syndrome. XX. The first 100 cancers
    • German J: Bloom's syndrome. XX. The first 100 cancers. Cancer Genet Cytogenet 93:100, 1997
    • (1997) Cancer Genet Cytogenet , vol.93 , pp. 100
    • German, J.1
  • 164
    • 0346351375 scopus 로고
    • A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes
    • Chaganti RS, Schonberg S, German J: A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes. Proc Natl Acad Sci USA 71:4508, 1974
    • (1974) Proc Natl Acad Sci USA , vol.71 , pp. 4508
    • Chaganti, R.S.1    Schonberg, S.2    German, J.3
  • 166
    • 3142544243 scopus 로고
    • Evidence for increased in vivo mutation and somatic recombination in Bloom's syndrome
    • Langlois RG, Bigbee WL, Jensen RH, German J: Evidence for increased in vivo mutation and somatic recombination in Bloom's syndrome. Proc Natl Acad Sci USA 86:670, 1989
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 670
    • Langlois, R.G.1    Bigbee, W.L.2    Jensen, R.H.3    German, J.4
  • 167
    • 0031802496 scopus 로고    scopus 로고
    • Somatic hypermutation of immunoglobulin genes is independent of the Bloom's syndrome DNA helicase
    • Sack SZ, Liu Y, German J, Green NS: Somatic hypermutation of immunoglobulin genes is independent of the Bloom's syndrome DNA helicase. Clin Exp Immunol 112:248, 1998
    • (1998) Clin Exp Immunol , vol.112 , pp. 248
    • Sack, S.Z.1    Liu, Y.2    German, J.3    Green, N.S.4
  • 170
    • 0025811882 scopus 로고
    • The SCID mouse mutant: Definition, characterization, and potential uses
    • Bosma MJ, Carroll AM: The SCID mouse mutant: Definition, characterization, and potential uses. Annu Rev Immunol 9:323, 1991
    • (1991) Annu Rev Immunol , vol.9 , pp. 323
    • Bosma, M.J.1    Carroll, A.M.2
  • 171
    • 0029881698 scopus 로고    scopus 로고
    • p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes
    • Bogue MA, Zhu C, Aguilar-Cordova E, Donehower LA, Roth DB: p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes. Genes Dev 10:553, 1996
    • (1996) Genes Dev , vol.10 , pp. 553
    • Bogue, M.A.1    Zhu, C.2    Aguilar-Cordova, E.3    Donehower, L.A.4    Roth, D.B.5
  • 172
    • 0029858143 scopus 로고    scopus 로고
    • V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors
    • Guidos CJ, Williams CJ, Grandal I, Knowles G, Huang MTF, Danska JS: V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors. Genes Dev 10:2038, 1996
    • (1996) Genes Dev , vol.10 , pp. 2038
    • Guidos, C.J.1    Williams, C.J.2    Grandal, I.3    Knowles, G.4    Huang, M.T.F.5    Danska, J.S.6
  • 176
    • 0031992186 scopus 로고    scopus 로고
    • V(D)J recombination is not required for the development of lymphoma in p53-deficient mice
    • Nacht M, Jacks T: V(D)J recombination is not required for the development of lymphoma in p53-deficient mice. Cell Growth Differ 9:131, 1998
    • (1998) Cell Growth Differ , vol.9 , pp. 131
    • Nacht, M.1    Jacks, T.2
  • 179
    • 0027319521 scopus 로고
    • p53 is required for radiation-induced apoptosis in mouse thymocytes
    • Lowe S, Schmitt EM, Smith SW, Osborne BA, Jacks T: p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362:847, 1993
    • (1993) Nature , vol.362 , pp. 847
    • Lowe, S.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 180
    • 0031170827 scopus 로고    scopus 로고
    • Essential and perilous: V(D)J recombination and DNA damage checkpoints in lymphocyte precursors
    • Danska JS, Guidos CJ: Essential and perilous: V(D)J recombination and DNA damage checkpoints in lymphocyte precursors. Semin Immunol 9:199, 1997
    • (1997) Semin Immunol , vol.9 , pp. 199
    • Danska, J.S.1    Guidos, C.J.2
  • 181
    • 0031137014 scopus 로고    scopus 로고
    • Different developmental arrest points in Rag-2-/- and SCID thymocytes on two genetic backgrounds
    • Diamond RA, Ward SB, Owada-Makabe K, Wang H, Rothenberg EV: Different developmental arrest points in Rag-2-/- and SCID thymocytes on two genetic backgrounds. J Immunol 158:4052, 1997
    • (1997) J Immunol , vol.158 , pp. 4052
    • Diamond, R.A.1    Ward, S.B.2    Owada-Makabe, K.3    Wang, H.4    Rothenberg, E.V.5
  • 182
    • 0030713009 scopus 로고    scopus 로고
    • Intraclonal molecular heterogeneity suggests a hierarchy of pathogenetic events in Burkitt's lymphoma
    • Gutierrez MI, Bhatia K, Cherney B, Capello D, Gaidano G, Magrath I: Intraclonal molecular heterogeneity suggests a hierarchy of pathogenetic events in Burkitt's lymphoma. Ann Oncol 8:987, 1997
    • (1997) Ann Oncol , vol.8 , pp. 987
    • Gutierrez, M.I.1    Bhatia, K.2    Cherney, B.3    Capello, D.4    Gaidano, G.5    Magrath, I.6
  • 187
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine AJ: p53, the cellular gatekeeper for growth and division. Cell 88:323, 1997
    • (1997) Cell , vol.88 , pp. 323
    • Levine, A.J.1
  • 192
    • 0032555201 scopus 로고    scopus 로고
    • Tumors of DNA mismatch repair-deficient hosts exhibit dramatic increases in genomic instability
    • Baross-Francis A, Andrew SE, Penney JE, Jirik FR: Tumors of DNA mismatch repair-deficient hosts exhibit dramatic increases in genomic instability. Proc Natl Acad Sci USA 95:8739, 1998
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8739
    • Baross-Francis, A.1    Andrew, S.E.2    Penney, J.E.3    Jirik, F.R.4
  • 193
    • 0029101616 scopus 로고
    • Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
    • de Wind N, Dekker M, Berns A, Radman M, te Riele H: Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer. Cell 82:321, 1995
    • (1995) Cell , vol.82 , pp. 321
    • De Wind, N.1    Dekker, M.2    Berns, A.3    Radman, M.4    Te Riele, H.5
  • 196
    • 0033106433 scopus 로고    scopus 로고
    • Intermolecular V(D)J recombination is prohibited specifically at the joining step
    • Han JO, Steen SB, Roth DB: Intermolecular V(D)J recombination is prohibited specifically at the joining step. Mol Cell 3:331, 1999
    • (1999) Mol Cell , vol.3 , pp. 331
    • Han, J.O.1    Steen, S.B.2    Roth, D.B.3
  • 197
    • 0028223271 scopus 로고
    • Cell cycle regulation of V(D)J recombination-activating protein RAG-2
    • Lin WC, Desiderio S: Cell cycle regulation of V(D)J recombination-activating protein RAG-2. Proc Natl Acad Sci USA 91:2733, 1994
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2733
    • Lin, W.C.1    Desiderio, S.2
  • 199
    • 0030999555 scopus 로고    scopus 로고
    • A breakpoint map of recurrent chromosomal rearrangements in human neoplasia
    • special number
    • Mitelman F, Mertens F, Johansson B: A breakpoint map of recurrent chromosomal rearrangements in human neoplasia. Nat Genet 15:417, 1997 (special number)
    • (1997) Nat Genet , vol.15 , pp. 417
    • Mitelman, F.1    Mertens, F.2    Johansson, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.