메뉴 건너뛰기




Volumn 5, Issue 6, 1996, Pages 505-511

Receptor editing, immune diversification, and self-tolerance

Author keywords

[No Author keywords available]

Indexed keywords

T LYMPHOCYTE RECEPTOR;

EID: 0030483540     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80266-6     Document Type: Review
Times cited : (160)

References (55)
  • 1
    • 0028358692 scopus 로고
    • Human lupus anti-DNA autoantibodies undergo essentially primary VK gene rearrangements
    • Bensimon, C., Chastagner, P., and Zouali, M. (1994). Human lupus anti-DNA autoantibodies undergo essentially primary VK gene rearrangements. EMBO J. 13, 2951-2962.
    • (1994) EMBO J. , vol.13 , pp. 2951-2962
    • Bensimon, C.1    Chastagner, P.2    Zouali, M.3
  • 2
    • 0026499970 scopus 로고
    • Conserved patterns of somatic mutation and secondary VH gene rearrangement create aberrant Ig-encoding genes in Epstein-Barr virus-transformed and normal human B lymphocytes
    • Brokaw, J.L., Wetzel, S.M., and Pollok, B.A. (1992). Conserved patterns of somatic mutation and secondary VH gene rearrangement create aberrant Ig-encoding genes in Epstein-Barr virus-transformed and normal human B lymphocytes. Int. Immunol. 4, 197-206.
    • (1992) Int. Immunol. , vol.4 , pp. 197-206
    • Brokaw, J.L.1    Wetzel, S.M.2    Pollok, B.A.3
  • 4
    • 0025042385 scopus 로고
    • A single pre-B cell can give rise to antigen-specific B cells that utilize distinct immunoglobulin gene rearrangements
    • Caton, A.J. (1990). A single pre-B cell can give rise to antigen-specific B cells that utilize distinct immunoglobulin gene rearrangements. J. Exp. Med. 172, 815-825.
    • (1990) J. Exp. Med. , vol.172 , pp. 815-825
    • Caton, A.J.1
  • 7
    • 0029553058 scopus 로고
    • Immunoglobulin heavy chain replacement: A mechanism of receptor editing
    • Chen, C., Nagy, Z., Prak, E.L., and Weigert, M. (1995b). Immunoglobulin heavy chain replacement: a mechanism of receptor editing. Immunity 3, 747-755.
    • (1995) Immunity , vol.3 , pp. 747-755
    • Chen, C.1    Nagy, Z.2    Prak, E.L.3    Weigert, M.4
  • 8
    • 0030997499 scopus 로고    scopus 로고
    • Editing disease-associated autoantibodies
    • in press
    • Chen, C., Prak, E.L., and Weigert, M. (1997). Editing disease-associated autoantibodies. Immunity, in press.
    • (1997) Immunity
    • Chen, C.1    Prak, E.L.2    Weigert, M.3
  • 9
    • 0025730554 scopus 로고
    • Vλ and Jλ-Cλ gene segments of the human immunoglobulin λ light chain locus are separated by 14 kb and rearrange by a deletion mechanism
    • Combriato, G., Klobeck, H.G., and Zachau, H.G. (1991). Vλ and Jλ-Cλ gene segments of the human immunoglobulin λ light chain locus are separated by 14 kb and rearrange by a deletion mechanism. Eur. J. Immunol. 21, 1513-1522.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 1513-1522
    • Combriato, G.1    Klobeck, H.G.2    Zachau, H.G.3
  • 10
    • 0028986982 scopus 로고
    • The human immunoglobulin VH repertoire
    • Cook, G.P., and Tomlinson, I.M. (1995). The human immunoglobulin VH repertoire. Immunol. Today 16, 237-242.
    • (1995) Immunol. Today , vol.16 , pp. 237-242
    • Cook, G.P.1    Tomlinson, I.M.2
  • 11
    • 0025325473 scopus 로고
    • VH to VHDJH rearrangement is mediated by the internal VH heptamer
    • Covey, L.R., Ferrier, P., and Alt, F.W. (1990). VH to VHDJH rearrangement is mediated by the internal VH heptamer. Int. Immunol. 2, 579-583.
    • (1990) Int. Immunol. , vol.2 , pp. 579-583
    • Covey, L.R.1    Ferrier, P.2    Alt, F.W.3
  • 12
    • 0025308620 scopus 로고
    • Immunoglobulin heavy chain gene rearrangement involving V-V region recombination
    • Deane, M., and Norton, J.D. (1990). Immunoglobulin heavy chain gene rearrangement involving V-V region recombination. Nucl. Acids Res. 18, 1652-1653.
    • (1990) Nucl. Acids Res. , vol.18 , pp. 1652-1653
    • Deane, M.1    Norton, J.D.2
  • 13
    • 0025980973 scopus 로고
    • Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice
    • Erikson, J., Radic, M.Z., Camper, S.A., Hardy, R.R., Carmack, C., and Weigert, M. (1991). Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice. Nature 349, 331-334.
    • (1991) Nature , vol.349 , pp. 331-334
    • Erikson, J.1    Radic, M.Z.2    Camper, S.A.3    Hardy, R.R.4    Carmack, C.5    Weigert, M.6
  • 14
    • 0022375583 scopus 로고
    • Double recombination of a single immunoglobulin K-chain allele: Implications for the mechanism of rearrangement
    • Feddersen, R.M., and Van Ness, B.G. (1985). Double recombination of a single immunoglobulin K-chain allele: implications for the mechanism of rearrangement. Proc. Natl. Acad. Sci. USA 82, 4793-4797.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 4793-4797
    • Feddersen, R.M.1    Van Ness, B.G.2
  • 15
    • 0030008694 scopus 로고    scopus 로고
    • The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help
    • Fulcher, D., Lyons, A., Korn, S., Cook, M., Koleda, C., Parish, C., Fazekas de St. Groth, B., and Basten, A. (1996). The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help. J. Exp. Med. 183, 2313-2328.
    • (1996) J. Exp. Med. , vol.183 , pp. 2313-2328
    • Fulcher, D.1    Lyons, A.2    Korn, S.3    Cook, M.4    Koleda, C.5    Parish, C.6    Fazekas De St. Groth, B.7    Basten, A.8
  • 16
    • 0027499537 scopus 로고
    • Receptor editing: An approach by autoreactive B cells to escape tolerance
    • Gay, D., Saunders, T., Camper, S., and Weigert, M. (1993). Receptor editing: an approach by autoreactive B cells to escape tolerance. J. Exp. Med. 177, 999-1008.
    • (1993) J. Exp. Med. , vol.177 , pp. 999-1008
    • Gay, D.1    Saunders, T.2    Camper, S.3    Weigert, M.4
  • 17
    • 0028856335 scopus 로고
    • Immature B cells from human and mouse bone marrow can change their surface light chain expression
    • Ghia, P., Gratwohl, A., Signer, E., Winkler, T.H., Melchers, F., and Rolink, A.G. (1995). Immature B cells from human and mouse bone marrow can change their surface light chain expression. Eur. J. Immunol. 25, 3108-3114.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 3108-3114
    • Ghia, P.1    Gratwohl, A.2    Signer, E.3    Winkler, T.H.4    Melchers, F.5    Rolink, A.G.6
  • 18
    • 0030460833 scopus 로고    scopus 로고
    • Neoteny in lymphocytes: Rag-1 and Rag-2 expression in germinal center B cells
    • Han, S., Zheng, B., Schatz, D.G., Spanopoulou, E., and Kelsoe, G. (1996). Neoteny in lymphocytes: Rag-1 and Rag-2 expression in germinal center B cells. Science 274, 2094.
    • (1996) Science , vol.274 , pp. 2094
    • Han, S.1    Zheng, B.2    Schatz, D.G.3    Spanopoulou, E.4    Kelsoe, G.5
  • 19
    • 0026016422 scopus 로고
    • Lack of feedback inhibition of VK gene rearrangement by productively rearranged alleles
    • Harada, K., and Yamagishi, H. (1991). Lack of feedback inhibition of VK gene rearrangement by productively rearranged alleles. J. Exp. Med. 173, 409-415.
    • (1991) J. Exp. Med. , vol.173 , pp. 409-415
    • Harada, K.1    Yamagishi, H.2
  • 20
    • 0028784215 scopus 로고
    • Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease
    • Hibbs, M., Tarlinton, D., Armes, J., Gail, D., Hodgson, G., Maglitto, R., Stacker, A., and Dunn, A. (1995). Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease. Cell 83, 301-311.
    • (1995) Cell , vol.83 , pp. 301-311
    • Hibbs, M.1    Tarlinton, D.2    Armes, J.3    Gail, D.4    Hodgson, G.5    Maglitto, R.6    Stacker, A.7    Dunn, A.8
  • 22
    • 0026612593 scopus 로고
    • Ongoing VK-JK recombination after formation of a productive VK-JK coding joint
    • Huber, C., Klobeck, H.G., and Zachau, H.G. (1992). Ongoing VK-JK recombination after formation of a productive VK-JK coding joint. Eur. J. Immunol. 22, 1561-1565.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 1561-1565
    • Huber, C.1    Klobeck, H.G.2    Zachau, H.G.3
  • 23
    • 0030199627 scopus 로고    scopus 로고
    • DNA methylation: A potential pathway to abnormal autoreactive lupus B cells
    • Huck, S., and Zouali, M. (1996). DNA methylation: a potential pathway to abnormal autoreactive lupus B cells. Clin. Immunol. Immunopathol. 80, 1-8.
    • (1996) Clin. Immunol. Immunopathol. , vol.80 , pp. 1-8
    • Huck, S.1    Zouali, M.2
  • 24
    • 0030811091 scopus 로고    scopus 로고
    • Expression of the tyrosine kinase Lyn during B-cell receptor engagement and apoptosis
    • in press
    • Huck, S., and Zouali, M. (1997). Expression of the tyrosine kinase Lyn during B-cell receptor engagement and apoptosis. Ann. NY Acad. Sci., in press.
    • (1997) Ann. NY Acad. Sci.
    • Huck, S.1    Zouali, M.2
  • 25
    • 0028784187 scopus 로고
    • Surrogate light chain-dependent selection of Ig heavy chain V regions
    • Keyna, U., Beck-Engesser, G., Jongstra, J., Applequist, S., and Jack, H.-M. (1995). Surrogate light chain-dependent selection of Ig heavy chain V regions. J. Immunol. 155, 5536-5542.
    • (1995) J. Immunol. , vol.155 , pp. 5536-5542
    • Keyna, U.1    Beck-Engesser, G.2    Jongstra, J.3    Applequist, S.4    Jack, H.-M.5
  • 26
    • 0022502863 scopus 로고
    • Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma
    • Kleinfield, R., Hardy, R.R., Tarlinton, D., Dangl, J., Herzenberg, L.A., and Weigert, M. (1986). Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma. Nature 322, 843-846.
    • (1986) Nature , vol.322 , pp. 843-846
    • Kleinfield, R.1    Hardy, R.R.2    Tarlinton, D.3    Dangl, J.4    Herzenberg, L.A.5    Weigert, M.6
  • 27
    • 0024475431 scopus 로고
    • Ig VH gene family repertoire of plasma cells derived from lupus-prone MRL/lpr and MRL/++ mice
    • Komisar, J.L., Leung, K.Y., Crawley, R.R., Talal, N., and Teale, J.M. (1989). Ig VH gene family repertoire of plasma cells derived from lupus-prone MRL/lpr and MRL/++ mice. J. Immunol. 143, 340-347.
    • (1989) J. Immunol. , vol.143 , pp. 340-347
    • Komisar, J.L.1    Leung, K.Y.2    Crawley, R.R.3    Talal, N.4    Teale, J.M.5
  • 28
    • 0024338847 scopus 로고
    • Functional immunoglobulin light chain genes are replaced by ongoing rearrangements of germline VK genes to downstream JK segment in a murine B cell line
    • Levy, S., Campbell, M.J., and Levy, R. (1989). Functional immunoglobulin light chain genes are replaced by ongoing rearrangements of germline VK genes to downstream JK segment in a murine B cell line. J. Exp. Med. 170, 1-13.
    • (1989) J. Exp. Med. , vol.170 , pp. 1-13
    • Levy, S.1    Campbell, M.J.2    Levy, R.3
  • 29
    • 0028048275 scopus 로고
    • The mechanism of V(D)J joining: Lessons from molecular, immunological, and comparative analyses
    • Lewis, S.M. (1994). The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses. Adv. Immunol. 56, 27-150.
    • (1994) Adv. Immunol. , vol.56 , pp. 27-150
    • Lewis, S.M.1
  • 30
    • 0020464847 scopus 로고
    • Continuing K-gene rearrangement in a cell line transformed by Abelson murine leukemia virus
    • Lewis, S., Rosenberg, N., Alt, F., and Baltimore, D. (1982). Continuing K-gene rearrangement in a cell line transformed by Abelson murine leukemia virus. Cell 30, 807-816.
    • (1982) Cell , vol.30 , pp. 807-816
    • Lewis, S.1    Rosenberg, N.2    Alt, F.3    Baltimore, D.4
  • 31
    • 0030586561 scopus 로고    scopus 로고
    • B cells selected for apoptosis in sheep ileal Peyer's patch have enhanced mutational diversity in the Ig Vλ light chain
    • Maybaum, T.A., and Reynolds, J.D. (1996). B cells selected for apoptosis in sheep ileal Peyer's patch have enhanced mutational diversity in the Ig Vλ light chain. J. Immunol. 157, 1474-1484.
    • (1996) J. Immunol. , vol.157 , pp. 1474-1484
    • Maybaum, T.A.1    Reynolds, J.D.2
  • 33
    • 0028806216 scopus 로고
    • Impaired proliferation of peripheral B cells and indication of autoimmune disease in Lyn-deficient mice
    • Nishizumi, H., Taniuchi, I., Yamanashi, Y., Kitamura, D., Ilic, D., Mori, S., Watanabe, T., and Yamamoto, T. (1995). Impaired proliferation of peripheral B cells and indication of autoimmune disease in Lyn-deficient mice. Immunity 3, 549-560.
    • (1995) Immunity , vol.3 , pp. 549-560
    • Nishizumi, H.1    Taniuchi, I.2    Yamanashi, Y.3    Kitamura, D.4    Ilic, D.5    Mori, S.6    Watanabe, T.7    Yamamoto, T.8
  • 34
    • 0028670390 scopus 로고
    • Apoptosis and macrophage-mediated cell deletion in the regulation of B lymphopoiesis in mouse bone marrow
    • Osmond, D.G., Rico-Vargas, S., Valenzona, H., Fauteux, L., Liu, L., Janani, R., Lu, L., and Jacobsen, K. (1994). Apoptosis and macrophage-mediated cell deletion in the regulation of B lymphopoiesis in mouse bone marrow. Immunol. Rev. 142, 209-230.
    • (1994) Immunol. Rev. , vol.142 , pp. 209-230
    • Osmond, D.G.1    Rico-Vargas, S.2    Valenzona, H.3    Fauteux, L.4    Liu, L.5    Janani, R.6    Lu, L.7    Jacobsen, K.8
  • 35
    • 0029164869 scopus 로고
    • Light chain replacement: A new model for antibody gene rearrangement
    • Prak, E.L., and Weigert, M. (1995). Light chain replacement: a new model for antibody gene rearrangement. J. Exp. Med. 182, 541-548.
    • (1995) J. Exp. Med. , vol.182 , pp. 541-548
    • Prak, E.L.1    Weigert, M.2
  • 36
    • 0029920268 scopus 로고    scopus 로고
    • The double edged sword of the immune response: Mutational analysis of a murine anti-pneumococcal, anti-DNA antibody
    • Putterman, C., Limpanasithikul, W., Edelman, M., and Diamond, B. (1996). The double edged sword of the immune response: mutational analysis of a murine anti-pneumococcal, anti-DNA antibody. J. Clin. Invest. 97, 2251-2259.
    • (1996) J. Clin. Invest. , vol.97 , pp. 2251-2259
    • Putterman, C.1    Limpanasithikul, W.2    Edelman, M.3    Diamond, B.4
  • 37
    • 0026029759 scopus 로고
    • Ig H and L chain contributions to autoimmune specificities
    • Radic, M.Z., Mascelli, M.A., Erikson, J., Shan, H., and Weigert, M. (1991). Ig H and L chain contributions to autoimmune specificities. J. Immunol. 146, 176-182.
    • (1991) J. Immunol. , vol.146 , pp. 176-182
    • Radic, M.Z.1    Mascelli, M.A.2    Erikson, J.3    Shan, H.4    Weigert, M.5
  • 38
    • 0027532192 scopus 로고
    • B lymphocytes may escape tolerance by revising their antigen receptors
    • Radic, M.Z., Erikson, J., Litwin, S., and Weigert, M. (1993a). B lymphocytes may escape tolerance by revising their antigen receptors. J. Exp. Med. 177, 1165-1173.
    • (1993) J. Exp. Med. , vol.177 , pp. 1165-1173
    • Radic, M.Z.1    Erikson, J.2    Litwin, S.3    Weigert, M.4
  • 40
    • 0022557584 scopus 로고
    • A novel VH to VHDJH joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production
    • Reth, M., Gehrmann, P., Petrac, E., and Wiese, P. (1986). A novel VH to VHDJH joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production. Nature 322, 840-842.
    • (1986) Nature , vol.322 , pp. 840-842
    • Reth, M.1    Gehrmann, P.2    Petrac, E.3    Wiese, P.4
  • 41
    • 0027274745 scopus 로고
    • Immature surface Ig+ B cells can continue to rearrange κ and λ L chain gene loci
    • Rolink, A., Grawunder, U., Haasner, D., Strasser, A., and Melchers, F. (1993). Immature surface Ig+ B cells can continue to rearrange κ and λ L chain gene loci. J. Exp. Med. 178, 1263-1270.
    • (1993) J. Exp. Med. , vol.178 , pp. 1263-1270
    • Rolink, A.1    Grawunder, U.2    Haasner, D.3    Strasser, A.4    Melchers, F.5
  • 42
    • 0030175708 scopus 로고    scopus 로고
    • Signals and susceptibility to programmed death in B cells
    • Rothstein, T. (1996). Signals and susceptibility to programmed death in B cells. Curr. Opin. Immunol. 8, 362-371.
    • (1996) Curr. Opin. Immunol. , vol.8 , pp. 362-371
    • Rothstein, T.1
  • 43
    • 0029994303 scopus 로고    scopus 로고
    • Analysis of central B cell tolerance in autoimmune-prone MRL/lpr mice bearing autoantibody transgenes
    • Rubio, C., Kench, J., Russel, D., Yawger, R., and Nemazee, D. (1996). Analysis of central B cell tolerance in autoimmune-prone MRL/lpr mice bearing autoantibody transgenes. J. Immunol. 157, 65-71.
    • (1996) J. Immunol. , vol.157 , pp. 65-71
    • Rubio, C.1    Kench, J.2    Russel, D.3    Yawger, R.4    Nemazee, D.5
  • 44
    • 0021770553 scopus 로고
    • Immunoglobulin gene 'remnant' DNA: Implications for antibody gene recombination
    • Selsing, E., Voss, J., and Storb, U. (1984). Immunoglobulin gene 'remnant' DNA: implications for antibody gene recombination. Nucl. Acids Res. 12, 4229-4246.
    • (1984) Nucl. Acids Res. , vol.12 , pp. 4229-4246
    • Selsing, E.1    Voss, J.2    Storb, U.3
  • 45
    • 0023578923 scopus 로고
    • How immunoglobulin VK genes rearrange
    • Shapiro, M.A., and Weigert, M. (1987). How immunoglobulin VK genes rearrange. J. Immunol. 139, 3834-3839.
    • (1987) J. Immunol. , vol.139 , pp. 3834-3839
    • Shapiro, M.A.1    Weigert, M.2
  • 47
    • 0028979455 scopus 로고
    • Rearrangement of upstream DH and VH genestoa rearranged immunoglobulin variable region gene inserted into the DQ52-JH region of the immunoglobulin heavy chain locus
    • Taki, S., Schwenk, F., and Rajewsky, K. (1995). Rearrangement of upstream DH and VH genestoa rearranged immunoglobulin variable region gene inserted into the DQ52-JH region of the immunoglobulin heavy chain locus. Eur. J. Immunol. 25, 1888-1896.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1888-1896
    • Taki, S.1    Schwenk, F.2    Rajewsky, K.3
  • 48
    • 0027478391 scopus 로고
    • Receptor editing in self-reactive bone marrow B cells
    • Tiegs, S.L., Russell, D.M., and Nemazee, D. (1993). Receptor editing in self-reactive bone marrow B cells. J. Exp. Med. 177, 1009-1020.
    • (1993) J. Exp. Med. , vol.177 , pp. 1009-1020
    • Tiegs, S.L.1    Russell, D.M.2    Nemazee, D.3
  • 50
    • 0021285559 scopus 로고
    • Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines
    • Yancopoulos, G.D., Desiderio, S.V., Paskind, M., Kearney, J.F., Baltimore, D., and Alt, F.W. (1984). Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines. Nature 311, 727-733.
    • (1984) Nature , vol.311 , pp. 727-733
    • Yancopoulos, G.D.1    Desiderio, S.V.2    Paskind, M.3    Kearney, J.F.4    Baltimore, D.5    Alt, F.W.6
  • 51
    • 0029947546 scopus 로고    scopus 로고
    • The transition of pre-BI to pre-BII cells is dependent on the VH structure of the μ/surrogate L chain receptor
    • Ye, J., McCray, S., and Clarke, S. (1996). The transition of pre-BI to pre-BII cells is dependent on the VH structure of the μ/surrogate L chain receptor. EMBO J. 75, 1524-1533.
    • (1996) EMBO J. , vol.75 , pp. 1524-1533
    • Ye, J.1    McCray, S.2    Clarke, S.3
  • 53
    • 0028305376 scopus 로고
    • Unravelling antibody genes
    • Zouali, M. (1994a). Unravelling antibody genes. Nature Genet. 7, 118-120.
    • (1994) Nature Genet. , vol.7 , pp. 118-120
    • Zouali, M.1
  • 55
    • 0023273826 scopus 로고
    • Murine lupus anti-DNA antibodies cross-react with the hapten (4-hydroxy-5-iodo-3-nitrophenyl)acetyl, but immunization-induced anti-DNA antibodies do not
    • Zouali, M., Migliorini, P., and Stollar, D.B. (1987). Murine lupus anti-DNA antibodies cross-react with the hapten (4-hydroxy-5-iodo-3-nitrophenyl)acetyl, but immunization-induced anti-DNA antibodies do not. Eur. J. Immunol. 17, 509-513.
    • (1987) Eur. J. Immunol. , vol.17 , pp. 509-513
    • Zouali, M.1    Migliorini, P.2    Stollar, D.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.