Inactivation of the ATM gene in T-cell prolymphocytic leukemias

Blood

Volumn 91, Issue 10, 1998, Pages 3920-3926

  Stoppa Lyonnet, Dominique ^b   Soulier, Jean ^b   Laugé, Anthony ^b   Dastot, Hélène ^b   Garand, Richard ^b   Sigaux, François ^b   Stern, Marc Henri ^a  

^a SAINT LOUIS HOSPITAL   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME 11Q; CLINICAL ARTICLE; CONTROLLED STUDY; GENE ISOLATION; GENE REPRESSION; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; LEUKEMOGENESIS; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; T LYMPHOCYTE; TUMOR SUPPRESSOR GENE;

EID: 0032525111     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v91.10.3920     Document Type: Article

References (43)

1. Matutes E, Brito-Bapapulle V, Swansbury J, Ellis J, Morilla R, Dearden C, Sempere A, Catovsky D: Clinical and laboratory features of 78 cases of T-prolymphocytic leukemia. Blood 78:3269, 1991
2. Stern MH, Soulier J, Rosenzwajg M, Nakahara K, Canki-Klain N, Aurias A, Sigaux F, Kirsch IR: MTCP-1: A novel gene on the human chromosome Xq28 translocated to the T cell receptor alpha/delta locus in mature T cell proliferations. Oncogene 8:2475, 1993
3. Fisch P, Forster A, Sherrington PD, Dyer MJ, Rabbitts TH: The chromosomal translocation t(X;14)(q28;q11) in T-cell pro-lymphocytic leukaemia breaks within one gene and activates another. Oncogene 8:3271, 1993
4. Virgilio L, Narducei MG, Isobe M, Billips LG, Cooper MD, Croce CM, Russo G: Identification of the TCLI gene involved in T-cell malignancies: Proc Natl Acad Sci USA 91:12530, 1994
5. Fu TB, Virgilio L, Narducci MG, Facchiano A, Russo G, Croce CM: Characterization and localization of the TCL-1 oncogene product. Cancer Res 54:6297, 1994
6. MTCP1 is restricted to T-cell proliferations with t(X;14) translocations. Blood 87:1923, 1996
7. Stern MH, Theodorou I, Aurias A, Maier-Redelsperger M, Debre M, Debre P, Griscelli C: T-cell nonmalignant clonal proliferation in ataxia telangiectasia: A cytological, immunological. and molecular characterization. Blood 73:1285, 1989
8. Stern MH: Clonal T-cell proliferations in ataxia telangiectasia, in Kirsch IR (ed): The Causes and Consequences of Chromosomal Aberrations. Boca Raton, FL, CRC, 1993, p 165
9. Taylor AMR, Metcalfe JA, Thick J, Mak YF: Leukemia and lymphoma in ataxia telangiectasia. Blood 87:423, 1996
10. Hecht F, McCaw BK, Koler RD: Ataxia-telangiectasia -clonal growth of translocation lymphocytes. N Engl J Med 289:286, 1973
11. McCaw BK, Hecht F, Harnden DG, Teplitz RL: Somatic rearrangement of chromosome 14 in human lymphocytes. Proc Natl Acad Sci USA 72:2071, 1975
12. Sparkes RS, Como R, Golde DW: Cytogenetic abnormalities in ataxia telangiectasia with T cell chronic lymphocytic leukemia. Cancer Genet Cytogenet 1:329, 1980
13. Taylor AMR, Oxford JM, Metcalfe JA: Spontaneous cytogenetic abnormalities in lymphocytes from thirteen patients with ataxia telangiectasia. Int J Cancer 27:311, 1981
14. Aurias A, Croquette MF, Nuyts JP, Griscelli C, Dutrillaux B: New data on clonal anomalies of chromosome 14 in ataxia telangiectasia: tct(14;14) and inv(14). Hum Genet 72:22, 1986
15. Thick J, Metcalfe JA, Mak YF, Beatty D, Minegishi M, Dyer MJ, Lucas G, Taylor AMR: Expression of either the TCL1 oncogene, or transcripts from its homologue MTCP1/c6.1B, in leukaemic and non-leukaemic T cells from ataxia telangiectasia patients. Oncogene 12:379, 1996
16. Narducci MG, Virgilio L, Isobe M, Stoppacciaro A, Elli R, Fiorilli M, Carbonari M, Antonelli A, Chessa L, Croce CM, Russo G: TCL1 oncogene activation in preleukemic T cells from a case of ataxia-telangiectasia. Blood 86:2358, 1995
17. Davey MP, Bertness V, Nakahara K, Johnson JP, McBride OW, Waldmann TA, Kirsch IR: Juxtaposition of the T-cell receptor alphachain locus (14q11) and a region (14q32) of potential importance in leukemogenesis by a 14;14 translocation in a patient with T-cell chronic lymphocytic leukemia and ataxia-telangiectasia. Proc Natl Acad Sci USA 85:9287, 1988
18. Taylor AMR, Butterworth SV: Clonal evolution of T-cell chronic lymphocytic leukaemia in a patient with ataxia telangiectasia. Int J Cancer 37:511, 1986
19. Taylor AMR, Lowe PA, Stacey M, Thick J, Campbell L, Beatty D, Biggs P, Formstone CJ: Development of T-cell leukaemia in an ataxia telangiectasia patient following clonal selection in t(X; 14)-containing lymphocytes. Leukemia 6:961, 1992
20. Barlow C, Hirotsune S, Paylor R, Liyanage M, Eckhaus M, Collins F, Shitoh Y, Crawley JN, Ried T, Tagle D, Wynshaw-Boris A: Atm-deficient mice: A paradigm of ataxia telangiectasia. Cell 86:159, 1996
21. Xu Y, Asley T, Brainerd EE, Bronson RT, Meyn MS, Baltimore D: Targeted disruption of ATM leads to growth retardation, chromo-somal fragmentation during meiosis, immune defects, and thymic lymphoma. Genes Dev 10:2411, 1996
22. Elson A, Wang Y, Daugherty CJ, Morton CC, Zhou F, Campos-Torres J, Leder P: Pleiotropic defects in ataxia-telangiectasia protein-deficient mice. Proc Natl Acad Sci USA 93:13084, 1996
23. Savitsky K, Bar-Shira A, Gilad S, Rotman G, Ziv Y, Vanagaite L, Tagle DA, Smith S, Uziel T, Sfez S, Ashkenazi M, Pecker I, Frydman M, Harnik R, Patanjali SR, Simmons A, Clines GA, Sartiel A, Gatti RA, Chessa L, Sanal O, Lavin MF, Jaspers NGJ, Taylor AMR, Arlett CF, Miki T, Weissman SM, Lovett M, Collins FS, Shiloh Y: A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 268:1749, 1995
24. Uziel T, Savitsky K, Platzer M, Ziv Y, Helbitz T, Nehls M, Boehm T, Rosenthal A, Shiloh Y, Rotman G: Genomic organization of the ATM gene. Genomics 33:317, 1996
25. Platzer M, Rotman G, Bauer D, Uziel T, Savitsky K, Bar-Shira A, Gilad S, Shiloh Y, Rosenthal A: Ataxia-telangiectasia locus: Sequence analysis of 184 kb of human genomic DNA containing the entire ATM gene. Genome Res 7:592, 1997
26. Savitsky K, Sfez S, Tagle DA, Ziv Y, Sartiel A, Collins FS, Shiloh Y, Rotman G: The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species. Hum Mol Genet 4:2025, 1995
27. Bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DAG, Gralnick HR, Sultan C: Proposals for the classification of chronic (mature) B and T lymphoid leukaemias. J Clin Pathol 42:567, 1989
28. Laake K, Ødegård Å, Andersen TI, Bukholm IK, Kåresen R, Nesland JM, Ottestad L, Shiloh Y, Børresen-Dale AL: Loss of heterozygosity at 11q23.1 in breast carcinomas: Indication for involvement of a gene distal and close to ATM. Genes Chromosom Cancer 18:175, 1997
29. Sambrook J, Fritsch EF, Maniatis T: Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory, 1989
30. Brown KD, Ziv Y, Sadanandan SN, Chessa L, Collins FS, Shiloh Y, Tagle DA: The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage. Proc Natl Acad Sci USA 94:1840, 1997
31. Vorechovsky I, Rasio D, Luo L, Monaco C, Hammarstrom L, Webster AD, Zaloudik J, Barbanti-Brodani G, James M, Russo G, Croce CM, Negrini M: The ATM gene and susceptibility to breast cancer: Analysis of 38 breast tumors reveals no evidence for mutation. Cancer Res 56:2726, 1996
32. Savitsky K, Sfez S, Tagle DA, Ziv Y, Sartiel A, Collins FS, Shiloh Y, Rotman G: The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species. Hum Mol Genet 4:2025, 1995
33. Gilad S, Khosravi R, Shkedy D, Uziel T, Ziv Y, Savitsky K, Rotman G, Smith S, Chessa L, Jorgensen TJ, Harnik R, Frydman M, Sanal O, Portnoi S, Goldwicz Z, Jaspers NG, Gatti RA, Lenoir G, Lavin MF, Tatsumi K, Wegner RD, Shiloh Y, Bar-Shira A: Predominance of null mutations in ataxia-telangiectasia. Hum Mol Genet 5:433, 1996
34. Telatar M, Wang Z, Udar N, Liang T, Bernatowska-Matuszkiewicz E, Lavin M, Shiloh Y, Concannon P, Good RA, Gatti RA: Ataxia-telangiectasia: Mutations in ATM cDNA detected by protein-truncation screening. Am J Hum Genet 59:40, 1996
35. Knudson A: Mutation and cancer: Statistical study of retinoblastoma. Proc Natl Acad Sci USA 68:820, 1971
36. Comings D: A general theory of carcinogenesis. Proc Natl Acad Sci USA 70:3324, 1973
37. Haber D, Harlow E: Tumour-suppressor genes: Evolving definitions in the genomic age. Nat Genet 16:320, 1997
38. Vorechovsky I, Luo L, Dyer MJ, Catovsky D, Amlot PL, Yaxley JC, Foroni L, Hammarstrom L, Webster AD, Yuille MA: Clustering of missense mutations in the ataxia-telangiectasia gene in a sporadic T-cell leukaemia. Nat Genet 17:96, 1997
39. Stilgenbauer S, Schaffner C, Litterst A, Liebisch P, Gilad S, Bar-Shira A, James MR, Lichter P, Döhner H: Biallelic mutations in the ATM gene in T-prolymphocytic leukemia. Nature Med 3:1155, 1997
40. Carter SL, Negrini M, Baffa R, Gillum DR, Rosenberg AL, Schwartz GF, Croce CM: Loss of heterozygosity at 11q22-q23 in breast cancer. Cancer Res 54:6270, 1994
41. Hampton GM, Mannermaa A, Winquist R, Alavaikko M, Blanco G, Taskinen PJ, Kiviniemi H, Newsham I, Cavenee WK, Evans GA: Loss of heterozygosity in sporadic human breast carcinoma: A common region between 11q22 and 11q23.3. Cancer Res 54:4586, 1994
42. Swift M, Morrell D, Massey RB, Chase CL: Incidence of cancer in 161 families affected by ataxia-telangiectasia. N Engl J Med 325:1831, 1991
43. Westphal CH: Cell-cycle signaling: Atm displays its many talents. Curr Biol 7:R789, 1997