-
1
-
-
0030006070
-
Clonal selection and learning in the antibody system
-
Rajewsky K. Clonal selection and learning in the antibody system. Nature 1996; 381:751-8.
-
(1996)
Nature
, vol.381
, pp. 751-758
-
-
Rajewsky, K.1
-
2
-
-
0023161406
-
Mutation drift and repertoire shift in the maturation of the immune response
-
Berek C, Milstein C. Mutation drift and repertoire shift in the maturation of the immune response. Immunol Rev 1987; 96:23-41.
-
(1987)
Immunol Rev
, vol.96
, pp. 23-41
-
-
Berek, C.1
Milstein, C.2
-
3
-
-
0029148418
-
Random mutagenesis of two complementarity determining region amino acids yields an unexpectedly high frequency of antibodies with increased affinity for both cognate antigen and autoantigen
-
Casson LP, Manser T. Random mutagenesis of two complementarity determining region amino acids yields an unexpectedly high frequency of antibodies with increased affinity for both cognate antigen and autoantigen. J Exp Med 1995; 182:743-50.
-
(1995)
J Exp Med
, vol.182
, pp. 743-750
-
-
Casson, L.P.1
Manser, T.2
-
4
-
-
0029928877
-
Life and death in germinal centers (redux)
-
Kelsoe G. Life and death in germinal centers (redux). Immunity 1996; 4:107-11.
-
(1996)
Immunity
, vol.4
, pp. 107-111
-
-
Kelsoe, G.1
-
5
-
-
0029927054
-
The mechanism of somatic hypermutation studied with transgenic and transfected target genes
-
Storb U, Peters A, Klotz E, Rogerson B, Hackett J Jr. The mechanism of somatic hypermutation studied with transgenic and transfected target genes. Semin Immunol 1996; 8:131-40.
-
(1996)
Semin Immunol
, vol.8
, pp. 131-140
-
-
Storb, U.1
Peters, A.2
Klotz, E.3
Rogerson, B.4
Hackett Jr., J.5
-
6
-
-
0027331383
-
Bloom syndrome - A mendelian prototype of somatic mutational disease
-
German J. Bloom syndrome - a mendelian prototype of somatic mutational disease. Med 1993; 72:393-406.
-
(1993)
Med
, vol.72
, pp. 393-406
-
-
German, J.1
-
7
-
-
0346351375
-
A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes
-
Chaganti RS, Schonberg S, German J. A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes. Proc Natl Acad Sci USA 1974; 71:4508-12.
-
(1974)
Proc Natl Acad Sci USA
, vol.71
, pp. 4508-4512
-
-
Chaganti, R.S.1
Schonberg, S.2
German, J.3
-
8
-
-
0024449142
-
Cell kinetic evidence suggests elevated oxidative stress in cultured cells of Bloom's syndrome
-
Poot M, Hoehn H, Nicotera TM, Rudiger HW. Cell kinetic evidence suggests elevated oxidative stress in cultured cells of Bloom's syndrome. Free Radic Res Commun 1989; 7:179-87.
-
(1989)
Free Radic Res Commun
, vol.7
, pp. 179-187
-
-
Poot, M.1
Hoehn, H.2
Nicotera, T.M.3
Rudiger, H.W.4
-
9
-
-
3142546346
-
A retarded rate of DNA chain growth in Bloom's syndrome
-
Hand R, German J. A retarded rate of DNA chain growth in Bloom's syndrome. Proc Natl Acad Sci USA 1975; 72:758-62.
-
(1975)
Proc Natl Acad Sci USA
, vol.72
, pp. 758-762
-
-
Hand, R.1
German, J.2
-
10
-
-
0025302748
-
An abnormal profile of DNA replication intermediates in Bloom's syndrome
-
Lonn U, Lonn S, Nylen U, Winblad G, German J. An abnormal profile of DNA replication intermediates in Bloom's syndrome. Cancer Res 1990; 50:3141-5.
-
(1990)
Cancer Res
, vol.50
, pp. 3141-3145
-
-
Lonn, U.1
Lonn, S.2
Nylen, U.3
Winblad, G.4
German, J.5
-
11
-
-
0028785586
-
The Bloom's syndrome gene product is homologous to RecQ helicases
-
Ellis NA, Groden J, Ye TZ, Straughen J, Lennon DJ, Clocci S, Proytcheva M, German J. The Bloom's syndrome gene product is homologous to RecQ helicases. Cell 1995; 83:655-66.
-
(1995)
Cell
, vol.83
, pp. 655-666
-
-
Ellis, N.A.1
Groden, J.2
Ye, T.Z.3
Straughen, J.4
Lennon, D.J.5
Clocci, S.6
Proytcheva, M.7
German, J.8
-
12
-
-
0027364921
-
Human xeroderma pigmentosum group D gene encodes a DNA helicase
-
Sung P, Bailly V, Weber C, Thompson LH, Prakash L, Prakash S. Human xeroderma pigmentosum group D gene encodes a DNA helicase. Nature 1993; 365:852-5.
-
(1993)
Nature
, vol.365
, pp. 852-855
-
-
Sung, P.1
Bailly, V.2
Weber, C.3
Thompson, L.H.4
Prakash, L.5
Prakash, S.6
-
13
-
-
0026465665
-
ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes
-
Troelstra C, van Gool A, de Wit J, Vermeulen W, Bootsma D, Hoeijmakers JH. ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes. Cell 1992; 71:939-53.
-
(1992)
Cell
, vol.71
, pp. 939-953
-
-
Troelstra, C.1
Van Gool, A.2
De Wit, J.3
Vermeulen, W.4
Bootsma, D.5
Hoeijmakers, J.H.6
-
14
-
-
0030602794
-
DNA helicases: New breeds of translocating motors and molecular pumps
-
West SC. DNA helicases: new breeds of translocating motors and molecular pumps. Cell 1996; 86:177-80.
-
(1996)
Cell
, vol.86
, pp. 177-180
-
-
West, S.C.1
-
15
-
-
0027953084
-
Normal V(D)J coding junction formation in DNA ligase I deficiency syndromes
-
Petrini JH, Donovan JW, Dimare C, Weaver DT. Normal V(D)J coding junction formation in DNA ligase I deficiency syndromes. J Immunol 1994; 152:176-83.
-
(1994)
J Immunol
, vol.152
, pp. 176-183
-
-
Petrini, J.H.1
Donovan, J.W.2
Dimare, C.3
Weaver, D.T.4
-
16
-
-
0027304013
-
V(D)J recombination in ataxia telangiectasia, Bloom's syndrome, and a DNA ligase I-associated immunodeficiency disorder
-
Hsieh CL, Arlett CF, Lieber MR. V(D)J recombination in ataxia telangiectasia, Bloom's syndrome, and a DNA ligase I-associated immunodeficiency disorder. J Biol Chem 1992; 268:20105-9.
-
(1992)
J Biol Chem
, vol.268
, pp. 20105-20109
-
-
Hsieh, C.L.1
Arlett, C.F.2
Lieber, M.R.3
-
17
-
-
0026544716
-
Reduced secreted mu mRNA synthesis in selective IgM deficiency of Bloom's syndrome
-
Kondo N, Ozawa T, Kato Y, Motoyoshi F, Kasahara K, Kameyama T, Orii T. Reduced secreted mu mRNA synthesis in selective IgM deficiency of Bloom's syndrome. Clin Exp Immunol 1992; 88:35-40.
-
(1992)
Clin Exp Immunol
, vol.88
, pp. 35-40
-
-
Kondo, N.1
Ozawa, T.2
Kato, Y.3
Motoyoshi, F.4
Kasahara, K.5
Kameyama, T.6
Orii, T.7
-
18
-
-
0026537477
-
Long-term study of the immunodeficiency of Bloom's syndrome
-
Kondo N, Motoyoshi F, Mori S, Kuwabara N, Orii T, German J. Long-term study of the immunodeficiency of Bloom's syndrome. Acta Paediatr 1992; 81:86-90.
-
(1992)
Acta Paediatr
, vol.81
, pp. 86-90
-
-
Kondo, N.1
Motoyoshi, F.2
Mori, S.3
Kuwabara, N.4
Orii, T.5
German, J.6
-
19
-
-
0028930758
-
Somatic mutation of human immunoglobulin V genes in the X-linked hyperIgM syndrome
-
Chu YW, Marin E, Fuleihan R, Ramesh N, Rosen FS, Geha RS, Insel RA. Somatic mutation of human immunoglobulin V genes in the X-linked hyperIgM syndrome. J Clin Invest 1995; 95:1389-93.
-
(1995)
J Clin Invest
, vol.95
, pp. 1389-1393
-
-
Chu, Y.W.1
Marin, E.2
Fuleihan, R.3
Ramesh, N.4
Rosen, F.S.5
Geha, R.S.6
Insel, R.A.7
-
20
-
-
0027216150
-
H usage and VDJ combinations in the human response to Haemophilus influenzae type b capsular polysaccharide. Nucleotide sequences of monospecific anti-Haemophilus antibodies and polyspecific antibodies cross-reacting with self antigens
-
H usage and VDJ combinations in the human response to Haemophilus influenzae type b capsular polysaccharide. Nucleotide sequences of monospecific anti-Haemophilus antibodies and polyspecific antibodies cross-reacting with self antigens. J Clin Invest 1993; 91:2734-43.
-
(1993)
J Clin Invest
, vol.91
, pp. 2734-2743
-
-
Adderson, E.E.1
Shackelford, P.G.2
Quinn, A.3
Wilson, P.M.4
Cunningham, M.W.5
Insel, R.A.6
Carroll, W.L.7
-
21
-
-
0029871507
-
Somatic hypermutation of Ig genes in patients with xeroderma pigmentosum (XP-D)
-
Wagner SD, Elvin JG, Norris P, McGregor JM, Neuberger MS. Somatic hypermutation of Ig genes in patients with xeroderma pigmentosum (XP-D). Int Immunol 1996; 8:701-5.
-
(1996)
Int Immunol
, vol.8
, pp. 701-705
-
-
Wagner, S.D.1
Elvin, J.G.2
Norris, P.3
McGregor, J.M.4
Neuberger, M.S.5
-
22
-
-
0028033316
-
Variable region gene analysis of B cell subsets derived from a 4-year-old child: Somatically mutated memory B cells accumulate in the peripheral blood already at young age
-
Klein U, Kuppers R, Rajewsky K. Variable region gene analysis of B cell subsets derived from a 4-year-old child: somatically mutated memory B cells accumulate in the peripheral blood already at young age. J Exp Med 1994; 180:1383-93.
-
(1994)
J Exp Med
, vol.180
, pp. 1383-1393
-
-
Klein, U.1
Kuppers, R.2
Rajewsky, K.3
-
24
-
-
0026443954
-
Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis
-
Rogozin IB, Kolchanov NA. Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis. Biochim Biophys Acta 1992; 1171:11-18.
-
(1992)
Biochim Biophys Acta
, vol.1171
, pp. 11-18
-
-
Rogozin, I.B.1
Kolchanov, N.A.2
-
25
-
-
0029947265
-
Di- And trinucleotide target preferences of somatic mutagenesis in normal and autoreactive B cells
-
Smith DS, Creadon G, Jena PK, Portanova JP, Kotzin BL, Wysocki LJ. Di-and trinucleotide target preferences of somatic mutagenesis in normal and autoreactive B cells. J Immunol 1996; 156:2642-52.
-
(1996)
J Immunol
, vol.156
, pp. 2642-2652
-
-
Smith, D.S.1
Creadon, G.2
Jena, P.K.3
Portanova, J.P.4
Kotzin, B.L.5
Wysocki, L.J.6
-
26
-
-
0025213248
-
V region gene usage and somatic mutation in the primary and secondary responses to influenza virus hemagglutinin
-
Clarke SH, Staudt LM, Kavaler J, Schwartz D, Gerhard WU, Weigert MG. V region gene usage and somatic mutation in the primary and secondary responses to influenza virus hemagglutinin. J Immunol 1990; 144:2795-801.
-
(1990)
J Immunol
, vol.144
, pp. 2795-2801
-
-
Clarke, S.H.1
Staudt, L.M.2
Kavaler, J.3
Schwartz, D.4
Gerhard, W.U.5
Weigert, M.G.6
-
28
-
-
0014019617
-
Origin of antibody variation
-
Brenner S, Milstein C. Origin of antibody variation. Nature 1966; 211:242-3.
-
(1966)
Nature
, vol.211
, pp. 242-243
-
-
Brenner, S.1
Milstein, C.2
-
29
-
-
0025183021
-
The efficiency of antibody affinity maturation: Can the rate of B-cell division be limiting?
-
Manser T. The efficiency of antibody affinity maturation: can the rate of B-cell division be limiting? Immunol Today 1990; 11:305-8.
-
(1990)
Immunol Today
, vol.11
, pp. 305-308
-
-
Manser, T.1
-
30
-
-
0031047442
-
Mechanism of antigen-driven somatic hypermutation of rearranged immunoglobulin V(D)J genes in the mouse
-
Steele EJ, Rothenfluh HS, Blanden RV. Mechanism of antigen-driven somatic hypermutation of rearranged immunoglobulin V(D)J genes in the mouse. Immunol Cell Biol 1997; 75:82-95.
-
(1997)
Immunol Cell Biol
, vol.75
, pp. 82-95
-
-
Steele, E.J.1
Rothenfluh, H.S.2
Blanden, R.V.3
-
31
-
-
15844409553
-
Positional cloning of the Werner's syndrome gene
-
Yu CE, Oshima J, Fu YH et al. Positional cloning of the Werner's syndrome gene. Science 1996; 272:258-62.
-
(1996)
Science
, vol.272
, pp. 258-262
-
-
Yu, C.E.1
Oshima, J.2
Fu, Y.H.3
-
32
-
-
0029887774
-
Mutation-causing mutations
-
Ellis NA. Mutation-causing mutations. Nature 1996; 381:110-1.
-
(1996)
Nature
, vol.381
, pp. 110-111
-
-
Ellis, N.A.1
-
33
-
-
0028033989
-
The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog - A potential eukaryotic reverse gyrase
-
Gangloff S, McDonald JP, Bendixen C, Arthur L, Rothstein R. The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog - a potential eukaryotic reverse gyrase. Mol Cell Biol 1994; 14:8391-8.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 8391-8398
-
-
Gangloff, S.1
McDonald, J.P.2
Bendixen, C.3
Arthur, L.4
Rothstein, R.5
-
34
-
-
0029002965
-
Sgs1: A eukaryotic homolog of E. coli Recq that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation
-
Watt PM, Louis EJ, Borts RH, Hickson ID. Sgs1: a eukaryotic homolog of E. coli Recq that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation. Cell 1995; 81:253-60.
-
(1995)
Cell
, vol.81
, pp. 253-260
-
-
Watt, P.M.1
Louis, E.J.2
Borts, R.H.3
Hickson, I.D.4
-
35
-
-
0029827768
-
Human homologues of yeast helicase
-
Lu J, Mullen JR, Brill SJ, Kleff S, Romeo AM, Sternglanz R. Human homologues of yeast helicase. Nature 1996; 383:678-9.
-
(1996)
Nature
, vol.383
, pp. 678-679
-
-
Lu, J.1
Mullen, J.R.2
Brill, S.J.3
Kleff, S.4
Romeo, A.M.5
Sternglanz, R.6
-
36
-
-
0030826311
-
Characterization of a new BLM mutation associated with a topoisomerase IIα defect in a patient with Bloom's syndrome
-
Foucault F, Vaury C, Barakat A, Thibout D, Planchon P, Jaulin C, Praz F, Amor-Gueret M. Characterization of a new BLM mutation associated with a topoisomerase IIα defect in a patient with Bloom's syndrome. Human Molec Genet 1997; 6:1427-34.
-
(1997)
Human Molec Genet
, vol.6
, pp. 1427-1434
-
-
Foucault, F.1
Vaury, C.2
Barakat, A.3
Thibout, D.4
Planchon, P.5
Jaulin, C.6
Praz, F.7
Amor-Gueret, M.8
-
37
-
-
0030761761
-
B lymphocytes of xeroderma pigmentosum or Cockayne syndrome patients with inherited defects in nucleotide excision repair are fully capable of somatic hypermutation of immunoglobulin genes
-
Nayun K, Kage K, Matsuda F, Lefranc MP, Storb U. B lymphocytes of xeroderma pigmentosum or Cockayne syndrome patients with inherited defects in nucleotide excision repair are fully capable of somatic hypermutation of immunoglobulin genes. J Exp Med 1997; 186:413-9.
-
(1997)
J Exp Med
, vol.186
, pp. 413-419
-
-
Nayun, K.1
Kage, K.2
Matsuda, F.3
Lefranc, M.P.4
Storb, U.5
|