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Volumn 112, Issue 2, 1998, Pages 248-254

Somatic hypermutation of immunoglobulin genes is independent of the Bloom's syndrome DNA helicase

Author keywords

Bloom's syndrome; Immunoglobulin; RecQ; Somatic mutation; Variable region

Indexed keywords

HELICASE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

EID: 0031802496     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1998.00575.x     Document Type: Article
Times cited : (15)

References (37)
  • 1
    • 0030006070 scopus 로고    scopus 로고
    • Clonal selection and learning in the antibody system
    • Rajewsky K. Clonal selection and learning in the antibody system. Nature 1996; 381:751-8.
    • (1996) Nature , vol.381 , pp. 751-758
    • Rajewsky, K.1
  • 2
    • 0023161406 scopus 로고
    • Mutation drift and repertoire shift in the maturation of the immune response
    • Berek C, Milstein C. Mutation drift and repertoire shift in the maturation of the immune response. Immunol Rev 1987; 96:23-41.
    • (1987) Immunol Rev , vol.96 , pp. 23-41
    • Berek, C.1    Milstein, C.2
  • 3
    • 0029148418 scopus 로고
    • Random mutagenesis of two complementarity determining region amino acids yields an unexpectedly high frequency of antibodies with increased affinity for both cognate antigen and autoantigen
    • Casson LP, Manser T. Random mutagenesis of two complementarity determining region amino acids yields an unexpectedly high frequency of antibodies with increased affinity for both cognate antigen and autoantigen. J Exp Med 1995; 182:743-50.
    • (1995) J Exp Med , vol.182 , pp. 743-750
    • Casson, L.P.1    Manser, T.2
  • 4
    • 0029928877 scopus 로고    scopus 로고
    • Life and death in germinal centers (redux)
    • Kelsoe G. Life and death in germinal centers (redux). Immunity 1996; 4:107-11.
    • (1996) Immunity , vol.4 , pp. 107-111
    • Kelsoe, G.1
  • 5
    • 0029927054 scopus 로고    scopus 로고
    • The mechanism of somatic hypermutation studied with transgenic and transfected target genes
    • Storb U, Peters A, Klotz E, Rogerson B, Hackett J Jr. The mechanism of somatic hypermutation studied with transgenic and transfected target genes. Semin Immunol 1996; 8:131-40.
    • (1996) Semin Immunol , vol.8 , pp. 131-140
    • Storb, U.1    Peters, A.2    Klotz, E.3    Rogerson, B.4    Hackett Jr., J.5
  • 6
    • 0027331383 scopus 로고
    • Bloom syndrome - A mendelian prototype of somatic mutational disease
    • German J. Bloom syndrome - a mendelian prototype of somatic mutational disease. Med 1993; 72:393-406.
    • (1993) Med , vol.72 , pp. 393-406
    • German, J.1
  • 7
    • 0346351375 scopus 로고
    • A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes
    • Chaganti RS, Schonberg S, German J. A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes. Proc Natl Acad Sci USA 1974; 71:4508-12.
    • (1974) Proc Natl Acad Sci USA , vol.71 , pp. 4508-4512
    • Chaganti, R.S.1    Schonberg, S.2    German, J.3
  • 8
    • 0024449142 scopus 로고
    • Cell kinetic evidence suggests elevated oxidative stress in cultured cells of Bloom's syndrome
    • Poot M, Hoehn H, Nicotera TM, Rudiger HW. Cell kinetic evidence suggests elevated oxidative stress in cultured cells of Bloom's syndrome. Free Radic Res Commun 1989; 7:179-87.
    • (1989) Free Radic Res Commun , vol.7 , pp. 179-187
    • Poot, M.1    Hoehn, H.2    Nicotera, T.M.3    Rudiger, H.W.4
  • 9
    • 3142546346 scopus 로고
    • A retarded rate of DNA chain growth in Bloom's syndrome
    • Hand R, German J. A retarded rate of DNA chain growth in Bloom's syndrome. Proc Natl Acad Sci USA 1975; 72:758-62.
    • (1975) Proc Natl Acad Sci USA , vol.72 , pp. 758-762
    • Hand, R.1    German, J.2
  • 10
    • 0025302748 scopus 로고
    • An abnormal profile of DNA replication intermediates in Bloom's syndrome
    • Lonn U, Lonn S, Nylen U, Winblad G, German J. An abnormal profile of DNA replication intermediates in Bloom's syndrome. Cancer Res 1990; 50:3141-5.
    • (1990) Cancer Res , vol.50 , pp. 3141-3145
    • Lonn, U.1    Lonn, S.2    Nylen, U.3    Winblad, G.4    German, J.5
  • 13
    • 0026465665 scopus 로고
    • ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes
    • Troelstra C, van Gool A, de Wit J, Vermeulen W, Bootsma D, Hoeijmakers JH. ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes. Cell 1992; 71:939-53.
    • (1992) Cell , vol.71 , pp. 939-953
    • Troelstra, C.1    Van Gool, A.2    De Wit, J.3    Vermeulen, W.4    Bootsma, D.5    Hoeijmakers, J.H.6
  • 14
    • 0030602794 scopus 로고    scopus 로고
    • DNA helicases: New breeds of translocating motors and molecular pumps
    • West SC. DNA helicases: new breeds of translocating motors and molecular pumps. Cell 1996; 86:177-80.
    • (1996) Cell , vol.86 , pp. 177-180
    • West, S.C.1
  • 15
    • 0027953084 scopus 로고
    • Normal V(D)J coding junction formation in DNA ligase I deficiency syndromes
    • Petrini JH, Donovan JW, Dimare C, Weaver DT. Normal V(D)J coding junction formation in DNA ligase I deficiency syndromes. J Immunol 1994; 152:176-83.
    • (1994) J Immunol , vol.152 , pp. 176-183
    • Petrini, J.H.1    Donovan, J.W.2    Dimare, C.3    Weaver, D.T.4
  • 16
    • 0027304013 scopus 로고
    • V(D)J recombination in ataxia telangiectasia, Bloom's syndrome, and a DNA ligase I-associated immunodeficiency disorder
    • Hsieh CL, Arlett CF, Lieber MR. V(D)J recombination in ataxia telangiectasia, Bloom's syndrome, and a DNA ligase I-associated immunodeficiency disorder. J Biol Chem 1992; 268:20105-9.
    • (1992) J Biol Chem , vol.268 , pp. 20105-20109
    • Hsieh, C.L.1    Arlett, C.F.2    Lieber, M.R.3
  • 20
    • 0027216150 scopus 로고
    • H usage and VDJ combinations in the human response to Haemophilus influenzae type b capsular polysaccharide. Nucleotide sequences of monospecific anti-Haemophilus antibodies and polyspecific antibodies cross-reacting with self antigens
    • H usage and VDJ combinations in the human response to Haemophilus influenzae type b capsular polysaccharide. Nucleotide sequences of monospecific anti-Haemophilus antibodies and polyspecific antibodies cross-reacting with self antigens. J Clin Invest 1993; 91:2734-43.
    • (1993) J Clin Invest , vol.91 , pp. 2734-2743
    • Adderson, E.E.1    Shackelford, P.G.2    Quinn, A.3    Wilson, P.M.4    Cunningham, M.W.5    Insel, R.A.6    Carroll, W.L.7
  • 21
  • 22
    • 0028033316 scopus 로고
    • Variable region gene analysis of B cell subsets derived from a 4-year-old child: Somatically mutated memory B cells accumulate in the peripheral blood already at young age
    • Klein U, Kuppers R, Rajewsky K. Variable region gene analysis of B cell subsets derived from a 4-year-old child: somatically mutated memory B cells accumulate in the peripheral blood already at young age. J Exp Med 1994; 180:1383-93.
    • (1994) J Exp Med , vol.180 , pp. 1383-1393
    • Klein, U.1    Kuppers, R.2    Rajewsky, K.3
  • 24
    • 0026443954 scopus 로고
    • Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis
    • Rogozin IB, Kolchanov NA. Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis. Biochim Biophys Acta 1992; 1171:11-18.
    • (1992) Biochim Biophys Acta , vol.1171 , pp. 11-18
    • Rogozin, I.B.1    Kolchanov, N.A.2
  • 25
    • 0029947265 scopus 로고    scopus 로고
    • Di- And trinucleotide target preferences of somatic mutagenesis in normal and autoreactive B cells
    • Smith DS, Creadon G, Jena PK, Portanova JP, Kotzin BL, Wysocki LJ. Di-and trinucleotide target preferences of somatic mutagenesis in normal and autoreactive B cells. J Immunol 1996; 156:2642-52.
    • (1996) J Immunol , vol.156 , pp. 2642-2652
    • Smith, D.S.1    Creadon, G.2    Jena, P.K.3    Portanova, J.P.4    Kotzin, B.L.5    Wysocki, L.J.6
  • 26
    • 0025213248 scopus 로고
    • V region gene usage and somatic mutation in the primary and secondary responses to influenza virus hemagglutinin
    • Clarke SH, Staudt LM, Kavaler J, Schwartz D, Gerhard WU, Weigert MG. V region gene usage and somatic mutation in the primary and secondary responses to influenza virus hemagglutinin. J Immunol 1990; 144:2795-801.
    • (1990) J Immunol , vol.144 , pp. 2795-2801
    • Clarke, S.H.1    Staudt, L.M.2    Kavaler, J.3    Schwartz, D.4    Gerhard, W.U.5    Weigert, M.G.6
  • 28
    • 0014019617 scopus 로고
    • Origin of antibody variation
    • Brenner S, Milstein C. Origin of antibody variation. Nature 1966; 211:242-3.
    • (1966) Nature , vol.211 , pp. 242-243
    • Brenner, S.1    Milstein, C.2
  • 29
    • 0025183021 scopus 로고
    • The efficiency of antibody affinity maturation: Can the rate of B-cell division be limiting?
    • Manser T. The efficiency of antibody affinity maturation: can the rate of B-cell division be limiting? Immunol Today 1990; 11:305-8.
    • (1990) Immunol Today , vol.11 , pp. 305-308
    • Manser, T.1
  • 30
    • 0031047442 scopus 로고    scopus 로고
    • Mechanism of antigen-driven somatic hypermutation of rearranged immunoglobulin V(D)J genes in the mouse
    • Steele EJ, Rothenfluh HS, Blanden RV. Mechanism of antigen-driven somatic hypermutation of rearranged immunoglobulin V(D)J genes in the mouse. Immunol Cell Biol 1997; 75:82-95.
    • (1997) Immunol Cell Biol , vol.75 , pp. 82-95
    • Steele, E.J.1    Rothenfluh, H.S.2    Blanden, R.V.3
  • 31
    • 15844409553 scopus 로고    scopus 로고
    • Positional cloning of the Werner's syndrome gene
    • Yu CE, Oshima J, Fu YH et al. Positional cloning of the Werner's syndrome gene. Science 1996; 272:258-62.
    • (1996) Science , vol.272 , pp. 258-262
    • Yu, C.E.1    Oshima, J.2    Fu, Y.H.3
  • 32
    • 0029887774 scopus 로고    scopus 로고
    • Mutation-causing mutations
    • Ellis NA. Mutation-causing mutations. Nature 1996; 381:110-1.
    • (1996) Nature , vol.381 , pp. 110-111
    • Ellis, N.A.1
  • 33
    • 0028033989 scopus 로고
    • The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog - A potential eukaryotic reverse gyrase
    • Gangloff S, McDonald JP, Bendixen C, Arthur L, Rothstein R. The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog - a potential eukaryotic reverse gyrase. Mol Cell Biol 1994; 14:8391-8.
    • (1994) Mol Cell Biol , vol.14 , pp. 8391-8398
    • Gangloff, S.1    McDonald, J.P.2    Bendixen, C.3    Arthur, L.4    Rothstein, R.5
  • 34
    • 0029002965 scopus 로고
    • Sgs1: A eukaryotic homolog of E. coli Recq that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation
    • Watt PM, Louis EJ, Borts RH, Hickson ID. Sgs1: a eukaryotic homolog of E. coli Recq that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation. Cell 1995; 81:253-60.
    • (1995) Cell , vol.81 , pp. 253-260
    • Watt, P.M.1    Louis, E.J.2    Borts, R.H.3    Hickson, I.D.4
  • 37
    • 0030761761 scopus 로고    scopus 로고
    • B lymphocytes of xeroderma pigmentosum or Cockayne syndrome patients with inherited defects in nucleotide excision repair are fully capable of somatic hypermutation of immunoglobulin genes
    • Nayun K, Kage K, Matsuda F, Lefranc MP, Storb U. B lymphocytes of xeroderma pigmentosum or Cockayne syndrome patients with inherited defects in nucleotide excision repair are fully capable of somatic hypermutation of immunoglobulin genes. J Exp Med 1997; 186:413-9.
    • (1997) J Exp Med , vol.186 , pp. 413-419
    • Nayun, K.1    Kage, K.2    Matsuda, F.3    Lefranc, M.P.4    Storb, U.5


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