메뉴 건너뛰기




Volumn 3, Issue 3, 1999, Pages 331-338

Intermolecular V(D)J recombination is prohibited specifically at the joining step

Author keywords

[No Author keywords available]

Indexed keywords

DNA; IMMUNOGLOBULIN J CHAIN;

EID: 0033106433     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80460-8     Document Type: Article
Times cited : (21)

References (38)
  • 1
    • 0030887862 scopus 로고    scopus 로고
    • RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination
    • Agrawal, A., and Schatz, D.G. (1997). RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination. Cell 89, 43-53.
    • (1997) Cell , vol.89 , pp. 43-53
    • Agrawal, A.1    Schatz, D.G.2
  • 2
    • 0031039088 scopus 로고    scopus 로고
    • Assessing the pathogenic potential of the V(D)J recombinase by interlocus immunoglobulin light-chain gene rearrangement
    • Bailey, S.N., and Rosenberg, N. (1997). Assessing the pathogenic potential of the V(D)J recombinase by interlocus immunoglobulin light-chain gene rearrangement. Mol. Cell. Biol. 17, 887-894.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 887-894
    • Bailey, S.N.1    Rosenberg, N.2
  • 3
    • 0029886929 scopus 로고    scopus 로고
    • Mechanism of V(D)J recombination
    • Bogue, M., and Roth, D.B. (1996). Mechanism of V(D)J recombination. Curr. Opin. Immunol. 8, 175-180.
    • (1996) Curr. Opin. Immunol. , vol.8 , pp. 175-180
    • Bogue, M.1    Roth, D.B.2
  • 4
    • 0030837472 scopus 로고    scopus 로고
    • V(D)J recombination in ku86-deficient mice: Distinct effects on coding, signal, and hybrid joint formation
    • Bogue, M.A., Wang, C., Zhu, C., and Roth, D.B. (1997). V(D)J recombination in ku86-deficient mice: Distinct effects on coding, signal, and hybrid joint formation. Immunity 7, 37-47.
    • (1997) Immunity , vol.7 , pp. 37-47
    • Bogue, M.A.1    Wang, C.2    Zhu, C.3    Roth, D.B.4
  • 5
    • 0024236673 scopus 로고
    • The mechanism of conservative site-specific recombination
    • Craig, N.L. (1988). The mechanism of conservative site-specific recombination. Annu. Rev. Genet. 22, 77-105.
    • (1988) Annu. Rev. Genet. , vol.22 , pp. 77-105
    • Craig, N.L.1
  • 6
    • 0029864993 scopus 로고    scopus 로고
    • Initiation of V(D)J recombination in vitro obeying the 12/23 rule
    • Eastman, Q.M., Leu, T.M.J., and Schatz, D.G. (1996). Initiation of V(D)J recombination in vitro obeying the 12/23 rule. Nature 380, 85-88.
    • (1996) Nature , vol.380 , pp. 85-88
    • Eastman, Q.M.1    Leu, T.M.J.2    Schatz, D.G.3
  • 7
    • 0029858143 scopus 로고    scopus 로고
    • V(D)J recombination activates a p53-dependent DNA damage checkpoint in scidlymphocyte precursors
    • Guidos, C.J., Williams, C.J., Grandal, I., Knowles, G., Huang, M.T.F., and Danska, J.S. (1996). V(D)J recombination activates a p53-dependent DNA damage checkpoint in scidlymphocyte precursors. Genes Dev. 10, 2038-2054.
    • (1996) Genes Dev. , vol.10 , pp. 2038-2054
    • Guidos, C.J.1    Williams, C.J.2    Grandal, I.3    Knowles, G.4    Huang, M.T.F.5    Danska, J.S.6
  • 8
    • 0030934860 scopus 로고    scopus 로고
    • Ku86 is not required for protection of signal ends or for formation of nonstandard V(D)J recombination products
    • Han, J.-O., Steen, S.B., and Roth, D.B. (1997). Ku86 is not required for protection of signal ends or for formation of nonstandard V(D)J recombination products. Mol. Cell. Biol. 17, 2226-2234.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2226-2234
    • Han, J.-O.1    Steen, S.B.2    Roth, D.B.3
  • 9
    • 0032529260 scopus 로고    scopus 로고
    • V(D)J recombination intermediates and non-standard products in xrcc4-deficient cells
    • Han, J.-O., Erskine, L.A., Purugganan, M.M., Stamato, T.D., and Roth, D.B. (1998). V(D)J recombination intermediates and non-standard products in xrcc4-deficient cells. Nucleic Acids Res. 26, 3769-3775.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 3769-3775
    • Han, J.-O.1    Erskine, L.A.2    Purugganan, M.M.3    Stamato, T.D.4    Roth, D.B.5
  • 10
    • 0032146072 scopus 로고    scopus 로고
    • Enhancer control of V(D)J recombination at the TCRβ locus: Differential effects on DNA cleavage and joining
    • Hempel, W.M., Stanhope-Baker, P., Mathieu, N., Huang, F., SchlisSel, M.S., and Ferrier, P. (1998). Enhancer control of V(D)J recombination at the TCRβ locus: Differential effects on DNA cleavage and joining. Genes Dev. 12, 2305-2317.
    • (1998) Genes Dev. , vol.12 , pp. 2305-2317
    • Hempel, W.M.1    Stanhope-Baker, P.2    Mathieu, N.3    Huang, F.4    Schlissel, M.S.5    Ferrier, P.6
  • 11
    • 0023659483 scopus 로고
    • Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V(D)J joining signals
    • Hesse, J.E., Lieber, M.R., Gellert, M., and Mizuuchi, K. (1987). Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V(D)J joining signals. Cell 49, 775-783.
    • (1987) Cell , vol.49 , pp. 775-783
    • Hesse, J.E.1    Lieber, M.R.2    Gellert, M.3    Mizuuchi, K.4
  • 12
    • 0024691453 scopus 로고
    • V(D)J recombination: A functional definition of the joining signals
    • Hesse, J.E., Lieber, M.R., Mizuuchi, K., and Gellert, M. (1989). V(D)J recombination: A functional definition of the joining signals. Genes Dev. 3, 1053-1061.
    • (1989) Genes Dev. , vol.3 , pp. 1053-1061
    • Hesse, J.E.1    Lieber, M.R.2    Mizuuchi, K.3    Gellert, M.4
  • 13
    • 0032084698 scopus 로고    scopus 로고
    • Assembly of a 12/23 paired signal complex: A critical control point in V(D)J recombination
    • Hiom, K., and Gellert, M. (1998). Assembly of a 12/23 paired signal complex: A critical control point in V(D)J recombination. Mol. Cell 1, 1011-1019.
    • (1998) Mol. Cell , vol.1 , pp. 1011-1019
    • Hiom, K.1    Gellert, M.2
  • 14
    • 0026721505 scopus 로고
    • Chromosomal translocations in lymphoid malignancies reveal novel proto-oncogenes
    • Korsmeyer, S.J. (1992). Chromosomal translocations in lymphoid malignancies reveal novel proto-oncogenes. Annu. Rev. Genet. 10, 785-807.
    • (1992) Annu. Rev. Genet. , vol.10 , pp. 785-807
    • Korsmeyer, S.J.1
  • 15
    • 0027983024 scopus 로고
    • P nucleotide insertions and the resolution of hairpin DNA structures in mammalian cells
    • Lewis, S.M. (1994). P nucleotide insertions and the resolution of hairpin DNA structures in mammalian cells. Proc. Natl. Acad. Sci. USA 91, 1332-1336.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 1332-1336
    • Lewis, S.M.1
  • 16
    • 0024255703 scopus 로고
    • Novel strand exchanges in V(D)J recombination
    • Lewis, S.M., Hesse, J.E., Mizuuchi, K., and Gellert, M. (1988). Novel strand exchanges in V(D)J recombination. Cell 55, 1099-1107.
    • (1988) Cell , vol.55 , pp. 1099-1107
    • Lewis, S.M.1    Hesse, J.E.2    Mizuuchi, K.3    Gellert, M.4
  • 17
    • 0023424487 scopus 로고
    • Developmental stage specificity of the lymphoid V(D)J recombination activity
    • Lieber, M.R., Hesse, J., Mizuuchi, K., and Gellert, M. (1987). Developmental stage specificity of the lymphoid V(D)J recombination activity. Genes Dev. 1, 751-761.
    • (1987) Genes Dev. , vol.1 , pp. 751-761
    • Lieber, M.R.1    Hesse, J.2    Mizuuchi, K.3    Gellert, M.4
  • 18
    • 0023801238 scopus 로고
    • The defect in murine severe combined immune deficiency: Joining of signal sequences but not coding segments in V(D)J recombination
    • Lieber, M.R., Hesse, J.E., Lewis, S., Bosma, G.C., Rosenberg, N., Mizuuchi, K., Bosma, M.J., and Gellert, M. (1988). The defect in murine severe combined immune deficiency: Joining of signal sequences but not coding segments in V(D)J recombination. Cell 55, 7-16.
    • (1988) Cell , vol.55 , pp. 7-16
    • Lieber, M.R.1    Hesse, J.E.2    Lewis, S.3    Bosma, G.C.4    Rosenberg, N.5    Mizuuchi, K.6    Bosma, M.J.7    Gellert, M.8
  • 19
    • 0024987973 scopus 로고
    • Hybrid T cell receptor genes formed by interlocus recombination in normal and ataxia-telangiectasia lymphocytes
    • Lipkowitz, S., Stern, M.-H., and Kirsch, I.R. (1990). Hybrid T cell receptor genes formed by interlocus recombination in normal and ataxia-telangiectasia lymphocytes. J. Exp. Med. 172, 409-418.
    • (1990) J. Exp. Med. , vol.172 , pp. 409-418
    • Lipkowitz, S.1    Stern, M.-H.2    Kirsch, I.R.3
  • 20
    • 0030874643 scopus 로고    scopus 로고
    • The absolute number of trans-rearrangements between the TCRG and TCRB loci is predictive of lymphoma risk: A severe combined immune deficiency (SCID) murine model
    • Lista, F., Bertness, V., Guidos, C., Danska, J.S., and Kirsch, I.R. (1997). The absolute number of trans-rearrangements between the TCRG and TCRB loci is predictive of lymphoma risk: A severe combined immune deficiency (SCID) murine model. Cancer Res. 57, 4408-4413.
    • (1997) Cancer Res. , vol.57 , pp. 4408-4413
    • Lista, F.1    Bertness, V.2    Guidos, C.3    Danska, J.S.4    Kirsch, I.R.5
  • 21
    • 0030069149 scopus 로고    scopus 로고
    • T-cell receptor α locus V(D)J recombination by-products are abundant in thymocytes and mature T cells
    • Livak, F., and Schatz, D.G. (1996). T-cell receptor α locus V(D)J recombination by-products are abundant in thymocytes and mature T cells. Mol. Cell. Biol. 16, 609-618.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 609-618
    • Livak, F.1    Schatz, D.G.2
  • 22
    • 0032502886 scopus 로고    scopus 로고
    • Rejoining of DNA by the RAG1 and RAG2 proteins
    • Melek, M., Gellert, M., and van Gent, D.c. (1998). Rejoining of DNA by the RAG1 and RAG2 proteins. Science 280, 301-303.
    • (1998) Science , vol.280 , pp. 301-303
    • Melek, M.1    Gellert, M.2
  • 23
    • 0021045079 scopus 로고
    • In vitro transposition of bacteriophage mu: A biochemical approach to a novel replication reaction
    • Mizuuchi, K. (1983). In vitro transposition of bacteriophage mu: A biochemical approach to a novel replication reaction. Cell 35, 785-794.
    • (1983) Cell , vol.35 , pp. 785-794
    • Mizuuchi, K.1
  • 25
    • 0030753633 scopus 로고    scopus 로고
    • Cell-free V(D)J recombination
    • Ramsden, D.A., Paull, T.T., and Gellert, M. (1997). Cell-free V(D)J recombination. Nature 388, 488-491.
    • (1997) Nature , vol.388 , pp. 488-491
    • Ramsden, D.A.1    Paull, T.T.2    Gellert, M.3
  • 26
    • 0026792892 scopus 로고
    • V(D)J recombination: Broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes
    • Roth, D.B., Menetski, J.P., Nakajima, P.B., Bosma, M.J., and Gellert, M. (1992). V(D)J recombination: Broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes. Cell 70, 983-991.
    • (1992) Cell , vol.70 , pp. 983-991
    • Roth, D.B.1    Menetski, J.P.2    Nakajima, P.B.3    Bosma, M.J.4    Gellert, M.5
  • 27
    • 0027491330 scopus 로고
    • Characterization of broken DNA molecules associated with V(D)J recombination
    • Roth, D.B., Zhu, C., and Gellert, M. (1993). Characterization of broken DNA molecules associated with V(D)J recombination. Proc. Natl. Acad. Sci. USA 90, 10788-10792.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10788-10792
    • Roth, D.B.1    Zhu, C.2    Gellert, M.3
  • 28
    • 0027770854 scopus 로고
    • Expression and V(D)J recombination activity of mutated RAG-1 proteins
    • Sadofsky, M.J., Hesse, J.E., McBlane, J.F., and Gellert, M. (1993). Expression and V(D)J recombination activity of mutated RAG-1 proteins. Nucleic Acids Res. 21, 5644-5650.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 5644-5650
    • Sadofsky, M.J.1    Hesse, J.E.2    McBlane, J.F.3    Gellert, M.4
  • 29
    • 0028237683 scopus 로고
    • Definition of a core region of RAG-2 that is functional in V(D)J recombination
    • Sadofsky, M.J., Hesse, J.E., and Gellert, M. (1994). Definition of a core region of RAG-2 that is functional in V(D)J recombination. NuCleic Acids Res. 22, 1805-1809.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 1805-1809
    • Sadofsky, M.J.1    Hesse, J.E.2    Gellert, M.3
  • 31
    • 0029983727 scopus 로고    scopus 로고
    • Accessibility control of antigen-receptor variable-region gene assembly: Role of cis-acting elements
    • Sleckman, B.P., Gorman, J.R., and Alt, F.W. (1996). Accessibility control of antigen-receptor variable-region gene assembly: Role of cis-acting elements. Annu. Rev. Immunol. 14, 459-481.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 459-481
    • Sleckman, B.P.1    Gorman, J.R.2    Alt, F.W.3
  • 32
    • 0030155949 scopus 로고    scopus 로고
    • The 12/23 rule is enforced at the cleavage step of V(D)J recombination in vivo
    • Steen, S.B., Gomelsky, L., and Roth, D.B. (1996). The 12/23 rule is enforced at the cleavage step of V(D)J recombination in vivo. Genes Cells 1, 543-553.
    • (1996) Genes Cells , vol.1 , pp. 543-553
    • Steen, S.B.1    Gomelsky, L.2    Roth, D.B.3
  • 33
    • 0025324784 scopus 로고
    • Chromosomal translocations in lymphoid neoplasia: A reappraisal of the recombinase model
    • Tycko, B., and Sklar, J. (1990). Chromosomal translocations in lymphoid neoplasia: A reappraisal of the recombinase model. CanCer Cells 2, 1-8.
    • (1990) Cancer Cells , vol.2 , pp. 1-8
    • Tycko, B.1    Sklar, J.2
  • 34
    • 0024427427 scopus 로고
    • T cell receptor gene trans-rearrangements: Chimeric γ-δ genes in normal lymphoid tissues
    • Tycko, B., Palmer, J.D., and Sklar, J. (1989). T cell receptor gene trans-rearrangements: Chimeric γ-δ genes in normal lymphoid tissues. Science 245, 1242-1246.
    • (1989) Science , vol.245 , pp. 1242-1246
    • Tycko, B.1    Palmer, J.D.2    Sklar, J.3
  • 35
    • 0025816509 scopus 로고
    • Chimeric γδ signal joints: Implications for the mechanism and regulation of T cell receptor gene rearrangement
    • Tycko, B., Coyle, H., and Sklar, J. (1991). Chimeric γδ signal joints: implications for the mechanism and regulation of T cell receptor gene rearrangement. J. Immunol. 147, 705-713.
    • (1991) J. Immunol. , vol.147 , pp. 705-713
    • Tycko, B.1    Coyle, H.2    Sklar, J.3
  • 36
    • 0030009253 scopus 로고    scopus 로고
    • The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination
    • van Gent, D.C., Ramsden, D.A., and Gellert, M. (1996). The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination. Cell 85, 107-113.
    • (1996) Cell , vol.85 , pp. 107-113
    • Van Gent, D.C.1    Ramsden, D.A.2    Gellert, M.3
  • 37
    • 0028958942 scopus 로고
    • Characterization of coding ends in thymocytes of scid mice: Implications for the mechanism of V(D)J recombination
    • Zhu, C., and Roth, D.B. (1995). Characterization of coding ends in thymocytes of scid mice: Implications for the mechanism of V(D)J recombination. Immunity 2, 101-112.
    • (1995) Immunity , vol.2 , pp. 101-112
    • Zhu, C.1    Roth, D.B.2
  • 38
    • 0030576534 scopus 로고    scopus 로고
    • Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates
    • Zhu, C., Bogue, M.A., Lim, D.-S., Hasty, P., and Roth, D.B. (1996). Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates. Cell 86, 379-389.
    • (1996) Cell , vol.86 , pp. 379-389
    • Zhu, C.1    Bogue, M.A.2    Lim, D.-S.3    Hasty, P.4    Roth, D.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.