메뉴 건너뛰기




Volumn 5, Issue 4, 1996, Pages 319-330

The SCID but not the RAG-2 gene product is required for Sμ-Sε heavy chain class switching

Author keywords

[No Author keywords available]

Indexed keywords

CD19 ANTIGEN; CD23 ANTIGEN; CD40 ANTIGEN; IMMUNOGLOBULIN HEAVY CHAIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY; PROTEIN KINASE;

EID: 0030273141     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80258-7     Document Type: Article
Times cited : (385)

References (75)
  • 1
    • 0027490279 scopus 로고
    • DNA damage and the DNA-activated protein kinase
    • Andersson, C.W. (1993). DNA damage and the DNA-activated protein kinase. Trends Biochem. Sci. 18, 433-437.
    • (1993) Trends Biochem. Sci. , vol.18 , pp. 433-437
    • Andersson, C.W.1
  • 4
    • 0027223391 scopus 로고
    • Human B cell proliferation and Ig secretion induced by recombinant CD40 ligand are modulated by soluble cytokines
    • Armitage, R.J., Macduff, B.M., Spriggs, M.K., and Fanslow, W.C. (1993). Human B cell proliferation and Ig secretion induced by recombinant CD40 ligand are modulated by soluble cytokines. J. Immunol. 150, 3671-3680.
    • (1993) J. Immunol. , vol.150 , pp. 3671-3680
    • Armitage, R.J.1    Macduff, B.M.2    Spriggs, M.K.3    Fanslow, W.C.4
  • 5
    • 0026092621 scopus 로고
    • Long-term human B cell lines dependent on interleukin-4 and antibody to CD40
    • Banchereau, J., de Paoli, P., Valle, A., Garcia, E., and Rousset, F. (1991). Long-term human B cell lines dependent on interleukin-4 and antibody to CD40. Science 251, 70-72.
    • (1991) Science , vol.251 , pp. 70-72
    • Banchereau, J.1    De Paoli, P.2    Valle, A.3    Garcia, E.4    Rousset, F.5
  • 6
    • 0025891769 scopus 로고
    • CD40 signaling activates CD11a/CD18 (LFA-1)-mediated adhesion in B cells
    • Barrett, T.B., Shu, G., and Clark, E.A. (1991). CD40 signaling activates CD11a/CD18 (LFA-1)-mediated adhesion in B cells. J. Immunol. 146, 1722-1729.
    • (1991) J. Immunol. , vol.146 , pp. 1722-1729
    • Barrett, T.B.1    Shu, G.2    Clark, E.A.3
  • 7
    • 0028152658 scopus 로고
    • Cross-linking CD40 on B cells rapidly activates nuclear factor κB
    • Berberich, I., Shu, G.L., and Clark, E.A. (1994). Cross-linking CD40 on B cells rapidly activates nuclear factor κB. J. Immunol. 153, 4357-4366.
    • (1994) J. Immunol. , vol.153 , pp. 4357-4366
    • Berberich, I.1    Shu, G.L.2    Clark, E.A.3
  • 8
    • 0344037977 scopus 로고
    • Synthesis of germline γ1 immunoglobulin heavy-chain transcript in resting B cells: Induction by interleukin 4 and inhibition by interferon γ
    • Berton, M.T., Uhr, J.W., and Vitetta, E.S. (1989). Synthesis of germline γ1 immunoglobulin heavy-chain transcript in resting B cells: induction by interleukin 4 and inhibition by interferon γ. Proc. Natl. Acad. Sci. USA 86, 2829-2833.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 2829-2833
    • Berton, M.T.1    Uhr, J.W.2    Vitetta, E.S.3
  • 9
    • 0019786306 scopus 로고
    • A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: Evidence for I region gene duplication
    • Bhattacharya, A., Dorf, M.E., and Springer, T.A. (1981). A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I region gene duplication. J. Immunol. 127, 2488-2495.
    • (1981) J. Immunol. , vol.127 , pp. 2488-2495
    • Bhattacharya, A.1    Dorf, M.E.2    Springer, T.A.3
  • 10
    • 0023002697 scopus 로고
    • Recombination between immunoglobulin variable region gene segments is enhanced by transcription
    • Blackwell, T.K., Moore, M.W., Yancopoulos, G.D., Suh, H., Lutzker, S., Selsing, E., and Alt, F.W. (1986). Recombination between immunoglobulin variable region gene segments is enhanced by transcription. Nature 324, 585-589.
    • (1986) Nature , vol.324 , pp. 585-589
    • Blackwell, T.K.1    Moore, M.W.2    Yancopoulos, G.D.3    Suh, H.4    Lutzker, S.5    Selsing, E.6    Alt, F.W.7
  • 12
    • 0020663062 scopus 로고
    • A severe combined immunodeficiency mutation in the mouse
    • Bosma, G.C., Custer, R.P., and Bosma, M.J. (1983). A severe combined immunodeficiency mutation in the mouse. Nature 301, 527-530.
    • (1983) Nature , vol.301 , pp. 527-530
    • Bosma, G.C.1    Custer, R.P.2    Bosma, M.J.3
  • 13
    • 0027952630 scopus 로고
    • S region transcription per se promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process
    • Bottaro, A., Lansford, R., Xu, L., Zhang, J., Rothman, P., and Alt, F.W. (1994). S region transcription per se promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process. EMBO J. 13, 665-674.
    • (1994) EMBO J. , vol.13 , pp. 665-674
    • Bottaro, A.1    Lansford, R.2    Xu, L.3    Zhang, J.4    Rothman, P.5    Alt, F.W.6
  • 15
    • 0027164915 scopus 로고
    • Regulation of expression of the ligand for CD40 on T helper lymphocytes
    • Castle, B.E., Kishimoto, K., Stearns, C., Brown, M.L., and Kehry, M.R. (1993). Regulation of expression of the ligand for CD40 on T helper lymphocytes. J. Immunol. 151, 1777-1788.
    • (1993) J. Immunol. , vol.151 , pp. 1777-1788
    • Castle, B.E.1    Kishimoto, K.2    Stearns, C.3    Brown, M.L.4    Kehry, M.R.5
  • 16
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and Sacchi, N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 17
    • 0026636784 scopus 로고
    • Quantitation of immunoglobulin μ-γ1 heavy chain switch region recombination by a digestion-circularization polymerase chain reaction method
    • Chu, C.C., Paul, W.E., and Max, E.E. (1992). Quantitation of immunoglobulin μ-γ1 heavy chain switch region recombination by a digestion-circularization polymerase chain reaction method. Proc. Natl. Acad. Sci. USA 89, 6978-6982.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6978-6982
    • Chu, C.C.1    Paul, W.E.2    Max, E.E.3
  • 18
    • 0025042313 scopus 로고
    • CD40: A cytokine receptor in search of a ligand
    • Clark, E.A. (1990). CD40: a cytokine receptor in search of a ligand. Tissue Antigens 36, 33-36.
    • (1990) Tissue Antigens , vol.36 , pp. 33-36
    • Clark, E.A.1
  • 19
    • 0010982635 scopus 로고
    • Activation of human B cells mediated through two distinct cell surface differentiation antigens, Bp35 and Bp50
    • Clark, E.A., and Ledbetter, J.A. (1986). Activation of human B cells mediated through two distinct cell surface differentiation antigens, Bp35 and Bp50. Proc. Natl. Acad. Sci. USA 83, 4494-4498.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 4494-4498
    • Clark, E.A.1    Ledbetter, J.A.2
  • 20
    • 0026601968 scopus 로고
    • Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease
    • Dürkop, H., Latza, U., Hummel, M., Eitelback, F., Seed, B., and Stein, H. (1992). Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease. Cell 68, 421-427.
    • (1992) Cell , vol.68 , pp. 421-427
    • Dürkop, H.1    Latza, U.2    Hummel, M.3    Eitelback, F.4    Seed, B.5    Stein, H.6
  • 21
    • 0024385049 scopus 로고
    • Rapid induction of transcription of unrearranged S γ1 switch regions in activated murine B cells by interleukin 4
    • Esser, C., and Radbruch, A. (1989). Rapid induction of transcription of unrearranged S γ1 switch regions in activated murine B cells by interleukin 4. EMBO J. 8, 483-488.
    • (1989) EMBO J. , vol.8 , pp. 483-488
    • Esser, C.1    Radbruch, A.2
  • 22
    • 0025210071 scopus 로고
    • Immunoglobulin class switching: Molecular and cellular analysis
    • Esser, C., and Radbruch, A. (1990). Immunoglobulin class switching: molecular and cellular analysis. Annu. Rev. Immunol. 8, 717-735.
    • (1990) Annu. Rev. Immunol. , vol.8 , pp. 717-735
    • Esser, C.1    Radbruch, A.2
  • 23
    • 0028276378 scopus 로고
    • CD40 signaling pathway: Anti-CD40 monoclonal antibody induces rapid dephosphorylation and phosphorylation of tyrosine-phosphorylated proteins including protein tyrosine kinase Lyn, Fyn, and Syk and the appearance of a 28-kD tyrosine phosphorylated protein
    • Faris, M., Gaskin, F., Parsons, J.T., and Fu, S.M. (1994). CD40 signaling pathway: anti-CD40 monoclonal antibody induces rapid dephosphorylation and phosphorylation of tyrosine-phosphorylated proteins including protein tyrosine kinase Lyn, Fyn, and Syk and the appearance of a 28-kD tyrosine phosphorylated protein. J. Exp. Med. 179, 1923-1931.
    • (1994) J. Exp. Med. , vol.179 , pp. 1923-1931
    • Faris, M.1    Gaskin, F.2    Parsons, J.T.3    Fu, S.M.4
  • 25
    • 0027530790 scopus 로고
    • Interferon-γ arrests proliferation and causes apoptosis in stromal cell/interleukin-7-dependent normal murine pre-B cell lines and clones in vitro, but does not induce differentiation to surface immunoglobulin-positive B cells
    • Grawunder, U., Melchers, F., and Rolink, A. (1993). Interferon-γ arrests proliferation and causes apoptosis in stromal cell/interleukin-7-dependent normal murine pre-B cell lines and clones in vitro, but does not induce differentiation to surface immunoglobulin-positive B cells. Eur. J. Immunol. 23, 544-551.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 544-551
    • Grawunder, U.1    Melchers, F.2    Rolink, A.3
  • 26
    • 0029584057 scopus 로고
    • Induction of sterile transcription from the κl chain gene locus in V(D)J-recombinase deficient progenitor B cells
    • Grawunder, U., Rolink, A., and Melchers, F. (1995). Induction of sterile transcription from the κL chain gene locus in V(D)J-recombinase deficient progenitor B cells. Int. Immunol. 7, 1915-1925.
    • (1995) Int. Immunol. , vol.7 , pp. 1915-1925
    • Grawunder, U.1    Rolink, A.2    Melchers, F.3
  • 27
    • 0027280936 scopus 로고
    • Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-IoxP-mediated gene targeting
    • Gu, H., Zou, Y.-R., and Rajewsky, K. (1993). Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-IoxP-mediated gene targeting. Cell 73, 1155-1164.
    • (1993) Cell , vol.73 , pp. 1155-1164
    • Gu, H.1    Zou, Y.-R.2    Rajewsky, K.3
  • 28
    • 0028136532 scopus 로고
    • Properties of mouse CD40: Cellular distribution of CD40 and B cell activation by monoclonal anti-mouse CD40 antibodies
    • Hasbold, J., Johnson-Leger, C., Atkins, C.J., Clark, E.A., and Klaus, G.G. (1994). Properties of mouse CD40: cellular distribution of CD40 and B cell activation by monoclonal anti-mouse CD40 antibodies. Eur. J. Immunol. 24, 1835-1842.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1835-1842
    • Hasbold, J.1    Johnson-Leger, C.2    Atkins, C.J.3    Clark, E.A.4    Klaus, G.G.5
  • 30
    • 0025650466 scopus 로고
    • CD40 and IgE: Synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells
    • Jabara, H.H., Fu, S.M., Geha, R.S., and Vercelli, D. (1990). CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells. J. Exp. Med. 172, 1861-1864.
    • (1990) J. Exp. Med. , vol.172 , pp. 1861-1864
    • Jabara, H.H.1    Fu, S.M.2    Geha, R.S.3    Vercelli, D.4
  • 31
    • 0028349260 scopus 로고
    • Ligation of CD40 induces sterile transcripts of multiple Ig H chain isotypes in human B cells
    • Jumper, M.D., Splawski, J.B., Lipsky, P.E., and Meek, K. (1994). Ligation of CD40 induces sterile transcripts of multiple Ig H chain isotypes in human B cells. J. Immunol. 152, 438-445.
    • (1994) J. Immunol. , vol.152 , pp. 438-445
    • Jumper, M.D.1    Splawski, J.B.2    Lipsky, P.E.3    Meek, K.4
  • 32
    • 0027417869 scopus 로고
    • Shutdown of class switch recombination by deletion of a switch region control element
    • Jung, S., Rajewsky, K., and Radbruch, A. (1993). Shutdown of class switch recombination by deletion of a switch region control element. Science 259, 984-987.
    • (1993) Science , vol.259 , pp. 984-987
    • Jung, S.1    Rajewsky, K.2    Radbruch, A.3
  • 33
    • 0023872192 scopus 로고
    • Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using a modified cDNA expression vectors
    • Karasuyama, H., and Melchers, F. (1988). Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using a modified cDNA expression vectors. Eur. J. Immunol. 18, 97-104.
    • (1988) Eur. J. Immunol. , vol.18 , pp. 97-104
    • Karasuyama, H.1    Melchers, F.2
  • 34
    • 0028447437 scopus 로고
    • The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation
    • Kawabe, T., Naka, T., Yoshida, K., Tanaka, T., Fujiwara, H., Suematsu, S., Yoshida, N., Kishimoto, T., and Kikutani, H. (1994). The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation. Immunity 1, 167-178.
    • (1994) Immunity , vol.1 , pp. 167-178
    • Kawabe, T.1    Naka, T.2    Yoshida, K.3    Tanaka, T.4    Fujiwara, H.5    Suematsu, S.6    Yoshida, N.7    Kishimoto, T.8    Kikutani, H.9
  • 35
    • 0027985361 scopus 로고
    • Properties of mouse CD40: The role of homotypic adhesion in the activation of B cells via CD40
    • Klaus, G.G.B., Holman, M., and Hasbold, J. (1994). Properties of mouse CD40: the role of homotypic adhesion in the activation of B cells via CD40. Eur. J. Immunol. 24, 2714-1719.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2714-11719
    • Klaus, G.G.B.1    Holman, M.2    Hasbold, J.3
  • 36
    • 0027360460 scopus 로고
    • Protein tyrosine phosphorylation is mandatory for CD40-mediated rescue of germinal center B cells from apoptosis
    • Knox, K.A., and Gordon, J. (1993). Protein tyrosine phosphorylation is mandatory for CD40-mediated rescue of germinal center B cells from apoptosis. Eur. J. Immunol. 23, 2578-2584.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 2578-2584
    • Knox, K.A.1    Gordon, J.2
  • 38
    • 0027515034 scopus 로고
    • Expression and functional properties of mouse B7/BB1 using a fusion protein between mouse CTLA4 and human γ1
    • Lane, P., Gerhard, W., Hubele, S., Lanzavecchia, A., and McConnell, F. (1993). Expression and functional properties of mouse B7/BB1 using a fusion protein between mouse CTLA4 and human γ1. Immunology 80, 56-61.
    • (1993) Immunology , vol.80 , pp. 56-61
    • Lane, P.1    Gerhard, W.2    Hubele, S.3    Lanzavecchia, A.4    McConnell, F.5
  • 39
    • 0021966190 scopus 로고
    • Monoclonal antibodies specific for murine IgM. II. Activation of B lymphocytes by monoclonal antibodies specific for the four constant domains of IgM
    • Leptin, M. (1985). Monoclonal antibodies specific for murine IgM. II. Activation of B lymphocytes by monoclonal antibodies specific for the four constant domains of IgM. Eur. J. Immunol. 15, 131-137.
    • (1985) Eur. J. Immunol. , vol.15 , pp. 131-137
    • Leptin, M.1
  • 40
    • 0023889066 scopus 로고
    • Mitogen- and IL-4-regulated expression of germ-line Igγ2b transcripts: Evidence for directed heavy chain class switching
    • Lutzger, S., Rothman, P., Pollock, R., Coffman, R., and Alt, F.W. (1988). Mitogen- and IL-4-regulated expression of germ-line Igγ2b transcripts: evidence for directed heavy chain class switching. Cell 53, 177-184.
    • (1988) Cell , vol.53 , pp. 177-184
    • Lutzger, S.1    Rothman, P.2    Pollock, R.3    Coffman, R.4    Alt, F.W.5
  • 42
    • 0026772133 scopus 로고
    • A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells
    • Noelle, R.J., Roy, M., Shepherd, D.M., Stamenkovic, I., Ledbetter, J.A., and Aruffo, A. (1992). A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells. Proc. Natl. Acad. Sci. USA 89, 6550-6554.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6550-6554
    • Noelle, R.J.1    Roy, M.2    Shepherd, D.M.3    Stamenkovic, I.4    Ledbetter, J.A.5    Aruffo, A.6
  • 43
    • 0024003645 scopus 로고
    • B cell ontogeny in murine embryo studied by a culture system with the monolayer of a stromal cell clone, ST-2: B cell progenitor develops first in the embryonal body rather than the yolk sac
    • Ogawa, M., Nishikawa, S., Ikuta, K., Yamamura, F., Naito, M., Takahashi, K., and Nishikawa, S.I. (1988). B cell ontogeny in murine embryo studied by a culture system with the monolayer of a stromal cell clone, ST-2: B cell progenitor develops first in the embryonal body rather than the yolk sac. EMBO J. 7, 1337-1343.
    • (1988) EMBO J. , vol.7 , pp. 1337-1343
    • Ogawa, M.1    Nishikawa, S.2    Ikuta, K.3    Yamamura, F.4    Naito, M.5    Takahashi, K.6    Nishikawa, S.I.7
  • 45
    • 0026744329 scopus 로고
    • Relative expression of surface IgM, IgD and the Ig-associating α(mb-1) and β(B-29) polypeptide chains
    • Parkhouse, R.M.E., Preece, G., Sutton, R., Cordell, J.L., and Mason, D.Y. (1992). Relative expression of surface IgM, IgD and the Ig-associating α(mb-1) and β(B-29) polypeptide chains. Immunology 76, 535-540.
    • (1992) Immunology , vol.76 , pp. 535-540
    • Parkhouse, R.M.E.1    Preece, G.2    Sutton, R.3    Cordell, J.L.4    Mason, D.Y.5
  • 46
    • 0024541563 scopus 로고
    • The human B lymphocyte and carcinoma antigen, CDw40, is a phosphoprotein involved in growth signal transduction
    • Paulie, S., Rosen, A., Ehlin-Henriksson, B., Braesch-Andersen, S., Jakobsen, E., Koho, H., and Perlmann, P. (1989). The human B lymphocyte and carcinoma antigen, CDw40, is a phosphoprotein involved in growth signal transduction. J. Immunol. 142, 590-595.
    • (1989) J. Immunol. , vol.142 , pp. 590-595
    • Paulie, S.1    Rosen, A.2    Ehlin-Henriksson, B.3    Braesch-Andersen, S.4    Jakobsen, E.5    Koho, H.6    Perlmann, P.7
  • 47
    • 0025225502 scopus 로고
    • Induction of RNA-stabilized DNA conformers by transcription of an immunoglobulin switch region
    • Reaban, M.E., and Griffin, M.A. (1990). Induction of RNA-stabilized DNA conformers by transcription of an immunoglobulin switch region. Nature 348, 342-344.
    • (1990) Nature , vol.348 , pp. 342-344
    • Reaban, M.E.1    Griffin, M.A.2
  • 48
    • 0026011211 scopus 로고
    • Long-term proliferating early preB cell lines and clones with the potential to develop to surface-Ig positive mitogen-reactive B cells "in vitro" and "in vivo."
    • Rolink, A., Kudo, A., Karasuyama, H., Kikuchi, Y., and Melchers, F. (1991). Long-term proliferating early preB cell lines and clones with the potential to develop to surface-Ig positive mitogen-reactive B cells "in vitro" and "in vivo." EMBO J. 10, 327-336.
    • (1991) EMBO J. , vol.10 , pp. 327-336
    • Rolink, A.1    Kudo, A.2    Karasuyama, H.3    Kikuchi, Y.4    Melchers, F.5
  • 51
    • 0025214025 scopus 로고
    • Structure and expression of germ line immunoglobulin heavy-chain ∈ transcripts: Interleukin-4 plus lipopolysaccharide-directed switching to c∈
    • Rothman, P., Chen, Y.Y., Lutzker, S., Li, S.C., Stewart, V., Coffman, R., and Alt, F.W. (1990). Structure and expression of germ line immunoglobulin heavy-chain ∈ transcripts: interleukin-4 plus lipopolysaccharide-directed switching to C∈. Mol. Cell. Biol. 10, 1672-1679.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 1672-1679
    • Rothman, P.1    Chen, Y.Y.2    Lutzker, S.3    Li, S.C.4    Stewart, V.5    Coffman, R.6    Alt, F.W.7
  • 57
    • 0027465755 scopus 로고
    • Towards a comprehensive view of immunoglobulin class switching
    • Snapper, C.M., and Mond, J.J. (1993). Towards a comprehensive view of immunoglobulin class switching. Immunol. Today 14, 15-17.
    • (1993) Immunol. Today , vol.14 , pp. 15-17
    • Snapper, C.M.1    Mond, J.J.2
  • 59
    • 0024414103 scopus 로고
    • A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas
    • Stamenkovic, I., Clark, E.A., and Seed, B. (1989). A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas. EMBO J. 8, 1403-1410.
    • (1989) EMBO J. , vol.8 , pp. 1403-1410
    • Stamenkovic, I.1    Clark, E.A.2    Seed, B.3
  • 60
    • 0022599997 scopus 로고
    • Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching
    • Stavnezer-Nordgren, J., and Sirlin, S. (1986). Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching. EMBO J. 5, 95-102.
    • (1986) EMBO J. , vol.5 , pp. 95-102
    • Stavnezer-Nordgren, J.1    Sirlin, S.2
  • 61
    • 0021963170 scopus 로고
    • Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells
    • Stavnezer-Nordgren, J., Sirlin, S., and Abbott, J. (1985). Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. J. Exp. Med. 161, 577-601.
    • (1985) J. Exp. Med. , vol.161 , pp. 577-601
    • Stavnezer-Nordgren, J.1    Sirlin, S.2    Abbott, J.3
  • 62
    • 0025786164 scopus 로고
    • bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship
    • Strasser, A., Harris, A.W., and Gory, S. (1991). bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell 67, 889-899.
    • (1991) Cell , vol.67 , pp. 889-899
    • Strasser, A.1    Harris, A.W.2    Gory, S.3
  • 63
    • 0020534965 scopus 로고
    • Somatic generation of antibody diversity
    • Tonegawa, S. (1983). Somatic generation of antibody diversity. Nature 302, 575-581.
    • (1983) Nature , vol.302 , pp. 575-581
    • Tonegawa, S.1
  • 64
    • 0026527783 scopus 로고
    • Differential increase of an alternatively polyadenylated mRNA species of murine CD40 upon B lymphocyte activation
    • Torres, R.M., and Clark, E.A. (1992). Differential increase of an alternatively polyadenylated mRNA species of murine CD40 upon B lymphocyte activation. J. Immunol. 148, 620-626.
    • (1992) J. Immunol. , vol.148 , pp. 620-626
    • Torres, R.M.1    Clark, E.A.2
  • 65
    • 0027236043 scopus 로고
    • B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40
    • Tsubata, T., Wu, J., and Honjo, T. (1993). B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40. Nature 364, 645-648.
    • (1993) Nature , vol.364 , pp. 645-648
    • Tsubata, T.1    Wu, J.2    Honjo, T.3
  • 66
    • 0025955702 scopus 로고
    • Stimulation of protein tyrosine phosphorylation, phosphoinositide turnover, and multiple previously unidentified serine/threonine-specific protein kinases by the pan-B-cell receptor CD40/Bp50 at discrete developmental stages of human B-cell ontogeny
    • Uckun, F.M., Schieven, G.L., Dibirdik, I., Chandan-Langlie, M.,TuelAhlgren, L., and Ledbetter, J.A. (1991). Stimulation of protein tyrosine phosphorylation, phosphoinositide turnover, and multiple previously unidentified serine/threonine-specific protein kinases by the pan-B-cell receptor CD40/Bp50 at discrete developmental stages of human B-cell ontogeny. J. Biol. Chem. 266, 17478-17485.
    • (1991) J. Biol. Chem. , vol.266 , pp. 17478-17485
    • Uckun, F.M.1    Schieven, G.L.2    Dibirdik, I.3    Chandan-Langlie, M.4    TuelAhlgren, L.5    Ledbetter, J.A.6
  • 68
    • 0027373275 scopus 로고
    • In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions
    • Van den Eertwegh, A.J.M., Noelle, R.J., Roy, M., Shepherd, D.M., Aruffo, A., Ledbetter, J.A., Boersma, W.J.A., and Claassen, E. (1993). In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions. J. Exp. Med. 178, 1555-1565.
    • (1993) J. Exp. Med. , vol.178 , pp. 1555-1565
    • Van Den Eertwegh, A.J.M.1    Noelle, R.J.2    Roy, M.3    Shepherd, D.M.4    Aruffo, A.5    Ledbetter, J.A.6    Boersma, W.J.A.7    Claassen, E.8
  • 69
    • 0028177788 scopus 로고
    • IFN-γ represses ∈ germline transcription and subsequently down-regulates switch recombination to ∈
    • Xu, L., and Rothman, P. (1994). IFN-γ represses ∈ germline transcription and subsequently down-regulates switch recombination to ∈. Int. Immunol. 6, 515-521.
    • (1994) Int. Immunol. , vol.6 , pp. 515-521
    • Xu, L.1    Rothman, P.2
  • 70
    • 0027416856 scopus 로고
    • Replacement of germline ∈ promoter by gene targeting alters control of immunoglobulin heavy chain class switching
    • Xu, L., Gorham, B., Li, S.C., Bottaro, A., and Alt, F.W. (1993). Replacement of germline ∈ promoter by gene targeting alters control of immunoglobulin heavy chain class switching. Proc. Natl. Acad. Sci. USA 90, 3705-3709.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3705-3709
    • Xu, L.1    Gorham, B.2    Li, S.C.3    Bottaro, A.4    Alt, F.W.5
  • 72
    • 0019735172 scopus 로고
    • Use of monoclonal anti-mouse immunoglobulin to detect mouse antibodies
    • Yelton, D.E., Desaymard, C., and Scharff, M.D. (1981). Use of monoclonal anti-mouse immunoglobulin to detect mouse antibodies. Hybridoma 1, 5-11.
    • (1981) Hybridoma , vol.1 , pp. 5-11
    • Yelton, D.E.1    Desaymard, C.2    Scharff, M.D.3
  • 73
    • 0027273019 scopus 로고
    • A selective defect in IgG2b switching as a result of targeted mutation of the Iγ2b promoter and exon
    • Zhang, J., Bottaro, A., Li, S., Steward, V., and Alt, F. (1993). A selective defect in IgG2b switching as a result of targeted mutation of the Iγ2b promoter and exon. EMBO J. 12, 3529-3537.
    • (1993) EMBO J. , vol.12 , pp. 3529-3537
    • Zhang, J.1    Bottaro, A.2    Li, S.3    Steward, V.4    Alt, F.5
  • 74
    • 0025762518 scopus 로고
    • CD40 stimulation provides an IFN-γ-independent and IL-4-dependent differentiation directly to human B cells for IgE production
    • Zhang, K., Clark, E.A., and Saxon, A. (1991). CD40 stimulation provides an IFN-γ-independent and IL-4-dependent differentiation directly to human B cells for IgE production. J. Immunol. 146, 1836-1842.
    • (1991) J. Immunol. , vol.146 , pp. 1836-1842
    • Zhang, K.1    Clark, E.A.2    Saxon, A.3
  • 75
    • 0026762983 scopus 로고
    • Two unusual forms of human immunoglobulin E encoded by alternative RNA splicing of ∈ heavy chain membrane exons
    • Zhang, K., Saxon, A., and Max, E.E. (1992). Two unusual forms of human immunoglobulin E encoded by alternative RNA splicing of ∈ heavy chain membrane exons. J. Exp. Med. 176, 233-243.
    • (1992) J. Exp. Med. , vol.176 , pp. 233-243
    • Zhang, K.1    Saxon, A.2    Max, E.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.