Chapter 15. Recent Developments in Cancer Cytotoxics

Annual Reports in Medicinal Chemistry

Volumn 33, Issue C, 1998, Pages 151-162

  Balasubramanian, Balu N ^a   Kadow, John F ^a   Kramer, Robert A ^a   Vyas, Dolatrai M ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0004901116     PISSN: 00657743     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0065-7743(08)61080-5     Document Type: Chapter

References (150)

1. Rennie J. Scientific American (1996) 1
2. Khayat D. Semin. Oncol. 24 (1997) S11
3. Cragg G.M., Newman D.J., and Weiss R.B. Semin. Oncol. 24 (1997) 156
4. Weiss R.B. Semin. Oncol. 24 (1997) 153
5. Monks A., Scudiero D.C., Johnson G.S., Paull K.D., and Sausville E.A. Anti-Cancer Drug Design 12 (1997)
6. Robert J. Drugs Fut. 22 (1997) 739
7. Workman P. Anti-Cancer Drug Design 12 (1997) 525
8. Brown J.M. Oncology Research 9 (1997) 213
9. Doyle T.W., and Vyas D.M. "Kirk-Othmer Encyclopedia of Chemical Technology Fourth Ed." (1993), John Wiley and Sons, New York, NY 870
10. Ecker G., and Chiba P. Exp. Opin. Ther. Patents 7 (1997) 589
11. Rowinsky E.K. Annu. Rev. Med. 48 (1997) 353
12. deFuria M.D. Phytomedicine 4 (1997) 273
13. Swindell C.S., Chirlian L.E., Francl M.M., Heerding J.M., Krauss N.E., Williams H.J., Scott A.I., and Dieden R.A. Tetrahedron 49 (1993) 6545
14. Moyna G., Williams H.J., Scott A.I., Ringel I., Gorodetsky R., and Swindell C.S. J. Med. Chem. 40 (1997) 3305
15. Guenard D., Dubois J., Gueritte-Voegelein F., Guedira N., Potier P., Gillet B., and Beloeil J.-C. Tetrahedron 49 (1993) 6533
16. Mastropaolo D., Camerman A., Luo Y., Brayer G.D., and Camerman N. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 6920
17. Georg G.I., Harriman G.C.B., Vanderveide D.G., Boge T.C., Cheruvallath Z.S., Datta A., Hepperie M., Park H., Himes R.H., and Jayasinghe L. "Taxane Anticancer Agents, ACS Symposium Series" (1995), American Chemical Society, Washington, DC 217
18. Ojima I., Kuduk S.D., Chakravarty S., Ourevitch M., and Begue J.P. J. Am. Chem. Soc. 119 (1997) 5519
19. Nogales E., Wolf S.G., and Downing K.H. Nature 391 (1998) 199
20. In: Suffness M. (Ed). "TAXOL® Science and Applications" (1995), CRC Press, Boca Raton, FL
21. Kingston D.G.I., Molinero A.A., and Rimoldi J.M. Prog. Chem. Org. Nat. Prod. 61 (1993) 1
22. Vyas D.M., and Kadow J.F. In: Luscombe G.P.E.a.D.K. (Ed). "Prog. Med. Chem" (1995), Elsevier, Amsterdam 289
23. All S.M., Hoemann M.Z., Aube J., Georg G.I., Mitscher L.A., and Jayasinghe L.R. J. Med. Chem. 40 (1997) 236
24. Chen S.H., Kadow J.F., Farina V., Fairchild C.R., and Johnston K.A. J. Org. Chem. 59 (1994) 6156
25. Chen S.-H., Wei J.-M., Long B.H., Fairchild C.A., Carboni J., Mamber S.W., Rose W.C., Johnston K., Casazza A.M., Kadow J.F., Vyas D.M., and Doyle T.W. Bioorg. Med. Chem. Lett. 5 (1995) 2741
26. Chaudhary A.G., Gharpure M.M., Rimoldi J.M., Chordia M.D., Gunatilaka A.A.L., and Kingston D.G.I. J. Am. Chem. Soc. 116 (1994) 4097
27. Ojima I., Duclos O., Kuduk S.D., Sun C.M., Slater J.C., Lavelle F., Veith J.M., and Bernacki R.J. Bioorg. Med. Chem. Lett. 4 (1994) 2631
28. Distefano M., Scambia G., Ferlini C., Gaggini C., DeVincenzo R., Riva A., Bombardelli E., Ojima I., Fattorossi A., Panici P.B., and Mancuso S. Int. J. Cancer 72 (1997) 844
29. Ojima I., Kuduk S.D., Pera P., Veith J.M., and Bernacki R.J. J. Med. Chem. 40 (1997) 279
30. Ojima I., Slater J.C., Michaud E., Kuduk S.C., Bounaud P.-Y., Vrignaud P., Bissery M.-C., Veith J., Pera P., and Bernacki R.J. J. Med. Chem. 39 (1996) 3889
31. Ojima I., Slater J.C., Kuduk S.D., Takeuchi C.S., Gimi R.H., Sun C.M., Park Y.H., Pera P., Veith J.M., and Bernacki R.J. J. Med. Chem. 40 (1997) 267
32. Vyas D.M. In: Farina V. (Ed). "The Chemistry and Pharmacology of TAXOL®" (1995), Elesevier, Amsterdam 103
33. Rose W.C., Clark J.L., Lee F.Y.F., and Casazza A.M. Cancer Chemother. Pharmacol. 39 (1997) 486
34. Senter P.D., Marquardt H., Thomas B.A., Hammock B.D., Frank I.S., and Svensson H.P. Cancer Res. 56 (1996) 1471
35. Ojima I., Bounaud P.-Y., Takeuchi C., Pera P., and Bernacki R.J. Bioorg. Med. Chem. Lett. 8 (1998) 189
36. Sarris, A.H., Younes, A., McLaughlin, P., Moore, D., Hagemeister, F., Swan, F., Rodriguez, M.A., Romaguera, J., North, L. and Cabanillas, F., Abstracts Submitted to the 36th Annual Meeting of the American Society of Hematology, Nashville, Tennessee, USA, December 2-6, 1994. Blood 84 (1994)
37. Berg S.L., Tolcher A., O'Shaughnessy J.A., Denicoff A.M., Noone M., Ognibene F.P., Cowan K.H., and Balls F.M. J. Clin. Oncol. 13 (1995) 2039
38. Peck R.L., Hewett J., Yang Y.-M., Chartuvedi P., Harding M., Hatch S., and Hawkins M.J. Proc. Am. Soc. Clin. Oncol. 16 (1997) 218a
39. Rowinsky E.L., Smith L., Chartuvedi P., Yang Y.-M., Campbell E., Hatch S., Harding M., Aylesworth C., Eckhardt G., Villalona M., Drengler R., Kraynak M., and Hoff D.V. Proc. Am. Soc. Clin. Oncol. 16 (1997) 218a
40. Broder, S., Duchin, K.L. and Selim, S., WO 97/15269, (1997)
41. Sparreboom A., vanAsperen J., Mayer U., Schinkel A.H., Smit J.W., Meijer D.K.F., Borst P., Nooijen W.J., Beijnen J.H., and vanTellingen O. Proc. Natl. Acad. Sci. USA 94 (1997) 2031
42. vanAsperen J., vanTellingen O., Sparreboom A., Schinkel A.H., Borst P., Nooijen W.J., and Beijnen J.H. Br. J. Cancer 76 (1997) 1181
43. Zhan A.R., Scala S., Monks A., Hose C., Bates S., and Fojo T. Cancer Chemother. Pharmacol. 40 (1997) 245
44. Benet, L. and Wu, C.Y., WO9520980 A1, (1995)
45. Hansel, S.B., PCT WO 9727855 AA, (1997)
46. ter Haar E., Kowalski R.J., Hamel E., Lin C.M., Longley R.E., Gunasekera S.P., Rosenkranz H.S., and Day B.W. Biochemistry 35 (1996) 243
47. Kowalski R.J., Glannakakou P., Gunasekera S.P., Longley R.E., Day B.W., and Hamel E. Mol. Pharmacol. 52 (1997) 613
48. Lindel T., Jensen P.R., Fenical W., Long B.H., Casazza A.M., Carboni J., and Fairchild C.R. J. Am. Chem. Soc. 119 (1997) 8744
49. Ciomei M., Albanese C., Pastori W., Grandi M., Pietra F., D'Ambrosio M., Guerriero A., and Battistinl C. Proc. Am. Assoc. Cancer Res. 38 (1997) 5 Abstract 30
50. Battistinl, C., Ciomei, M., Pietra, F., D'Ambroslo, M. & Gurriero, A., WO 9636335, (1996)
51. Fenical, W.H., Jensen, P.R. and Lindel, T., 5,473,057, (1995)
52. Bollag D.M., McQueney P.A., Zhu J., Hensens O., Koupal L., Liesch J., Goetz M., Lazarides E., and Woods C.M. Cancer Res. 55 (1995) 2325
53. Nicolaou K.C., Xu J.Y., Kim S., Ohshima T., Hosokawa S., and Pfefferkorn J. J. Am. Chem. Soc. 119 (1997) 11353
54. Nicolaou K.C., vanDelft F., Ohshima T., Vourioumis D., Xu J.Y., Hosokawa S., Pfefferkorn J., Kim S., and Li T.H. Angew. Chem. Int. Ed. Engl. 36 (1997) 2520
55. Hofle G., Bedorf N., Steinmetz H., Schomberg D., Gerth K., and Reichenbach H. Angew. Chem. Int. Ed. Engl. 35 (1996) 1567
56. Bollag D.M. Exp. Opin. Invest. Drugs 6 (1997) 867
57. Kowalski R.J., Terhaar E., Longley R.E., Gunasekera S.P., Lin C.M., Day B.V., and Hamel E. Molecular Biology of the Cell 6 (1995) 2137
58. Kowalski R.J., Glannakakou P., and Hamel E. J. Biol. Chem. 272 (1997) 2534
59. Balog A., Meng D.F., Kamenecka T., Bertinato P., Su D.S., Sorensen E.J., and Danishefsky S. Angew. Chem. Int. Ed. Engl. 35 (1997) 2801
60. Nicolaou K.C., He Y., Vourioumis D., Vallberg H., Roschangar F., Sarabia F., Ninkovic S., Yang Z., and Trujillo J.I. J. Am. Chem. Soc. 119 (1997) 7960
61. Nicolaou K.C., Vourioumis D., Li T.H., Pastor J., Winssinger N., He Y., Ninkovic S., Sarabia F., Vallberg H., Roschangar F., King N.P., Finlay M.R.V., Giannakakou P., VerdierPinard P., and Hamel E. Angew. Chem. Int. Ed. Engl. 36 (1997) 2097
62. Nicolaou K.C., Winssinger N., Pastor J., Ninkovic S., Sarabia F., He Y., Vourioumis D., Yang Z., Li T., Giannakakou P., and Hamel E. Nature 387 (1997) 268
63. Nicolaou K.C., Sarabia F., Ninkovic S., and Yang Z. Angew. Chem. Int. Ed. Engl. 36 (1997) 525
64. Nicolaou K.C., Ninkovic S., Sarabia F., Vourioumis D., He Y., Vallberg H., Finlay M.R.V., and Yang Z. J. Am. Chem. Soc. 119 (1997) 7974
65. Su D.S., Meng D.F., Bertinato P., Balog A., Sorensen E.J., Danishefsky S.J., Zheng Y.H., Chou T.C., He L.F., and Horwitz S.B. Angew. Chem. Int. Ed. Engl. 36 (1997) 757
66. Yang Z., He Y., Vourioumis D., Vallberg H., and Nicolaou K.C. Angew. Chem. Int. Ed. Engl. 36 (1997) 166
67. Schinzer D., Limberg A., Bauer A., Bohm O., and Cordes M. Angew. Chem. Int. Ed. Engl. 36 (1997) 523
68. Su D.S., Balog A., Meng D.F., Bertinato P., Danishefsky S.J., Zheng Y.H., Chou T.C., He L.F., and Horwitz S.B. Angew. Chem. Int. Ed. Engl. 36 (1997) 2093
69. Piccart M. Cancer Treat. Rev. 23 (1997) S59
70. Lavelle F. Exp. Opin. Invest. Drugs 6 (1997) 771
71. Petit G.R., Xu J., Hogan F., Williams M.D., Doubek D.L., Schmidt J.M., Cerny R.L., and Boyd M.R. J. Nat. Prod. 60 (1997) 752
72. Yamada K., and Kigoshi H. Bull. Chem. Soc. Jpn. 70 (1997) 1479
73. Petit G.R., Xu J., Hogan F., and Cerny R.L. Heterocycles 47 (1998) 491
74. Horita K., Nagasawa M., Hachiya S., Sakural Y., Yamazaki T., Uenishi J., and Yonemitsu O. Tetrahedron Lett. 38 (1997) 8965
75. Golakotl T., Ohtani I., Patterson G.M.L., Corbett T.H., Valeriote F.A., and Demchik L. J. Am. Chem. Soc. 117 (1994) 2479
76. Panda D., Himes R.H., Moore R.E., Wilson L., and Jordan M.A. Biochemistry 36 (1997) 12948
77. Smith C.D., and Zhang X. J. Biol. Chem. 271 (1996) 6192
78. Mooberry S.L., Busquets L., and Tien G. Int J Cancer 73 (1997) 440
79. Worzalla J.F., Cao J., Ehlhardt W.J., Harrison S.D., Law K.L., Martinelli M.J., Self T.D., Starling J.J., Shih C., Theobald K.S., Toth J.E., Zimmerman J.L., and Corbett T.H. Proc. Am. Assoc. Cancer Res. 34 (1997) 225 Abstract 1516
80. Corbett T., Valeriote F., and Simpson C. Proc. Am. Assoc. Cancer Res. 38 (1997) 225 Abstract 1515
81. Polin L., Valeriote F., Moore R., Tius M., Hemscheidt B.R.T., Liang J., Palik S., White K., Harrison S., Shih J., Martinelli M., and Corbett T. Proc. Am. Assoc. Cancer Res. 38 (1997) 225 Abstract 1514
82. Anderson H.J., Coleman J.E., Andersen R.J., and Roberge M. Cancer Chemother. Pharmacol. 39 (1997) 223
83. Anderson R.L., Coleman J.E., Piers E.L., and Wallace D.J. Tetrahedron Lett. 38 (1997) 317
84. Yoshimatsu K., Yamaguchi A., Yoshino H., Koyanagi N., and Tachibana K.K. Cancer Res. 57 (1997) 3208
85. Carmichael J. Exp. Opin. Invest. Drugs. 6 (1997) 593
86. Boisseau M., Guichard S., Canal P., and Bugat R. Exp. Opin. Invest. Drugs 5 (1996) 613
87. Wang H.-K., Morris-Natschke S.L., and Lee K.-H. Med. Res. Rev. 17 (1997) 367
88. Prudhomme M. Curr. Pharm. Design 3 (1997) 265
89. Ahmed A.E., Jacob S., Giovanella B.C., Kozielski A.J., Liehr J.G., and Stehlin J.S. Cancer Chemother. Pharmacol. 41 (1997) 29
90. Joto N., Ishii M., Minami M., Kuga H., Mitsui I., and Tohgo A. Int J Cancer 72 (1997) 680
91. Fang F.G., Bankston D.D., Huie E.M., Johnson M.R., Kang M.C., LeHoullier C.S., Lewis G.C., Lovelace T.C., Lowery M.W., McDougald D.L., Meerholz C.A., Partridge J.J., Sharp M.J., and Xie S.P. Tetrahedron 53 (1997) 10953
92. Lackey K., Sternbach D.D., Croom D.K., Emerson D.L., Evans M.G., Leitner P.L., Luzzio M.J., McIntyre G., Vuong A., Yates J., and Besterman J.M. J. Med. Chem. 39 (1996) 713
93. Candiani I., Bedeschi A., Cabri W., Zarini F., Visentin G., Capolongo L., Geroni C., and Ciomel M. Bioorg. Med. Chem. Lett. 7 (1997) 847
94. Carrigan S., Fox P.C., Wall M.E., Wani M.C., and Bowen J.P. J. Computer-Aided Molec. Design 11 (1997) 71
95. Cao Z.S., Harris N., Kozielski A., Vardeman D., Stehlin J.S., and Giovanella B. J Med Chem 41 (1998) 31
96. Josien H., Bom D., Curran D.P., Zheng Y.H., and Chou T.C. Bioorg. Med. Chem. Lett. 7 (1997) 3189
97. Verschraegen C.F., Natelson E.A., Giovanella B.C., Kavanagh J.J., Kudelka A.P., Freedman R.S., Edwards C.L., Ende K., and Stehlin J.S. Anti Cancer Drug 9 (1998) 36
98. Bailly C., Riou J.-F., Colson P., Houssier C., Rodrigues-Pereira E., and Prudhomme M. Biochemistry 36 (1997) 3917
99. Long B.H., Fairchild C.A., Bifano M., and Kramer R. Proc. Am. Assoc. Cancer Res. 38 (1997) 75
100. Arakawa H., Iguchi T., Morita M., Yoshinari T., Kojiri K., Suda H., Okura A., and Nidhimura S. Cancer Research 55 (1995) 1316
101. Ohkubo M., Kawamoto H., Ohno T., Nakano M., and Morishima H. Tetrahedron 53 (1997) 585
102. Anizon F., Belin L., Moreau P., Sancelme M., Voldoire A., Prudhomme M., Ollier M., Severe D., Riou J.F., Bailly C., Fabbro D., and Meyer T. J. Med. Chem. 40 (1997) 3456
103. Gatto B., Sanders M., Yu C., Wu H.-Y., Makhey D., LaVoie E.J., and Liu L.F. Cancer Res. 56 (1996) 2795
104. Insaf S.S., Danks M.K., and Witiak D.T. Curr. Pharm. Design 3 (1996) 437
105. Madalenegoitia J.S., Tepe J.J., Werbovitz K.A., Lehnert E.K., and Macdonald T.L. Biorg. Med. Chem. 5 (1997) 1807
106. Spicer J.A., Gamage S.A., Atwell G.J., Finley G.J., Baguley B.C., and Denny W.A. J. Med. Chem. 40 (1997) 1919
107. Denny W.A. Exp. Opin. Invest. Drugs. 6 (1997) 1845
108. Vasey P.A., and Kaye S.B. Br. J. Cancer 76 (1997) 1395
109. Takimoto C.H. Semin. Oncol. 24 (1997) 40
110. Kamen B. Semin. Oncol. 24 (1997) 30
111. Blanke C.D., Messenger M., and Taplin S.C. Semin. Oncol. 24 (1997) 57
112. Peters G.J., and Ackland S.P. Exp. Opin. Invest. Drugs 5 (1996) 637
113. Kadhim S.A., Bowlin T.L., Wand W.R., Angers E.G., Bibeau L., DeMuys J.M., Bednarski K., Cimpoia A., and Attardo G. Cancer Res. 57 (1997) 4803
114. Li J., Chen S.H., Li X.Y., Niu C.S., and Doyle T.W. Tetrahedron 54 (1998) 393
115. Liu M.-C., Lin T.-S., and Sartorelli A.C. J. Med. Chem. 35 (1992) 3672
116. Szekeres T., FritzerSzekeres M., and Elford H.L. Crit Rev. Clin. Lab. Sci. 34 (1997) 503
117. Moore M.J., Tannock I.F., Ernst D.S., Huan S., and Murray N. J. Clin. Oncol. 15 (1997) 3441
118. Sun L.Q., Li Y.X., Guillou L., Mirimanoff R.O., and Couck P.A. Cancer Res. 57 (1997) 4023
119. D'Incalci M., and Sessa C. Exp. Opin. Invest. Drugs 6 (1997) 875
120. Asai A., Nagamura S., and Saito H. J. Am. Chem. Soc. 116 (1994) 4171
121. Kobayashi E., Okamoto A., Asada M., Okabe M., Nagamura S., Asai A., Saito H., Gomi K., and Hirata T. Cancer Res. 54 (1994) 2404
122. Nagamura S., Asai A., Kanda Y., Kobayashi E., Gomi K., and Saito H. Chem. Pharm. Bull. 44 (1996) 1723
123. Boger D.L., Garbaccio R.M., and Jin Q. J. Org. Chem. 62 (1997) 8875
124. Patel V.F., Andis S.L., Enkema J.K., Johnson D.A., Kennedy J.H., Mohamadi F., Schultz R.M., Soose D.J., and Spees M.M. J. Org. Chem. 62 (1997) 8868
125. Arcamone F., Animati F., Capranico G., Lombardi P., Pratesi G., Manzini S., Supino R., and Zunino F. Pharmacol. Ther. 76 (1997) 117
126. Richardson D.S., Kelsey S.M., Johnson S.A., Tighe M., Cavenagh J.D., and Newland A.C. Invest. New Drugs 15 (1997) 247
127. Cherney R.J., Swartz S.G., Patten A.D., Akamike E., Sun J.-H., Kaltenbach III R.F., Seitz S.P., Behrens C.H., Getahun Z., Trainor G.L., Vavala M., Kirshenbaum M.R., Papp L.M., Stafford M.P., Czerniak P.M., Diamond R.J., McRipley R.J., Page R.J., and Gross J.L. Bioorg. Med. Chem. Lett. 7 (1997) 163
128. Mitra K., Kim W., Daniels J.S., and Gates K.S. J. Am. Chem. Soc. 119 (1997) 11691
129. Greenwald R.B. Exp. Opin. Ther. Patents 7 (1997) 601
130. Blakey D. Exp. Opin. Ther. Patents 7 (1997) 965
131. Melton R.G., Knox R.J., and Connors T.A. Drugs Fut. 21 (1996) 167
132. Jack D.B. Scrip (1997) 23
133. Holmes J. The Pharm. Journal 257 (1996) 294
134. Ladino C.A., Chari R.V.J., Bourret L.A., Kedersha N.L., and Goldmacher V.S. Int. J. Cancer 73 (1997) 859
135. Arap W., Pasqualini R., and Ruoslahti E. Science 279 (1998) 377
136. Hung D.T., Jamison T.F., and Schreiber S.L. Chem. and Biol. 3 (1996) 623
137. Uhr J.W., Scheuermann R.H., Street N.E., and Vitetta E.S. Nat. Med. 3 (1997) 505
138. Folkman J. Nature Med. 1 (1995) 27
139. Seed M.P. Exp. Opin. Invest. Drugs 5 (1997) 1617
140. Sharma S., Raymond E., Soda H., and VonHoff D.D. Exp. Opin. Invest. Drugs 6 (1997) 1179
141. Yang D., and Wang S. Curr. Pharm. Design 3 (1997) 335
142. Konstantopoulos N., and Burgess A. Mol. Med. Today (1997) 284
143. Sebti S.M., and Hamilton A.D. Pharmacol. Ther. 74 (1997) 103
144. Sebti S.M., and Hamilton A.D. DDT 3 (1998) 26
145. Lerner E.C., Hamilton A.D., and Sebti S.M. Anti Cancer Drug Design 12 (1997) 229
146. Sugita K., and Ohtani M. Curr. Pharm. Drugs 3 (1997) 323
147. Traxler P.M. Exp. Opin. Ther. Patents 7 (1997) 571
148. Burke T.R., Yao Z.-J., Smyth M.S., and Ye B. Curr. Pharm. Design 3 (1997) 291
149. Zhang M., Martin K.J., Sheng S., and Sager R. Trends. Bio-Tech. 16 (1998) 66
150. Ershler W.B., and Longo D.L. J. Natl. Cancer Inst. 89 (1997) 1489