Synthesis and structure-activity relationships of nonaromatic taxoids: Effects of alkyl and alkenyl ester groups on cytotoxicity

Journal of Medicinal Chemistry

Volumn 40, Issue 3, 1997, Pages 279-285

  Ojima, Iwao ^a   Kuduk, Scott D ^a   Pera, Paula ^b   Veith, Jean M ^b   Bernacki, Ralph J ^b  

^a STONY BROOK UNIVERSITY   (United States)

^b ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BACCATIN III; DOCETAXEL; PACLITAXEL; TERPENOID DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CHEMICAL MODIFICATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BREAST NEOPLASMS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; ESTERS; FEMALE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; OVARIAN NEOPLASMS; PACLITAXEL; STRUCTURE-ACTIVITY RELATIONSHIP; TAXOIDS; TUMOR CELLS, CULTURED;

EID: 0031049783     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9606711     Document Type: Article

References (32)

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