Total Synthesis of (-)-Epothilone A

Angewandte Chemie (International Edition in English)

Volumn 36, Issue 5, 1997, Pages 523-524

  Schinzer, Dieter ^a,b   Limberg, Anja ^a   Bauer, Armin ^a   Böhm, Oliver M ^a   Cordes, Martin ^a  

^a TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^b Chemisches Institut der Universitat   (Germany)

Author keywords

Aldol reactions; Epothilones; Metathesis; Natural products; Total synthesis

Indexed keywords

EID: 0030894922     PISSN: 05700833     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.199705231     Document Type: Article

References (18)

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15. Traces of the corresponding diastereomer can only be detected if the aldol reaction is carried out on a one gram scale.
16. W. J. Zuercher, M. Hashimoto, R. H. Grubbs; J. W. Ziller J. Am. Chem. Soc. 1996, 118, 100-110.
17. The name epothilone C was proposed by G. Höfle, whom we thank for a sample of 19.
18. The main product of this inaction is 1, which is chromatographically and spectroscopically identical to an authentic sample. We thank G. Höfle for a sample of 1.