Identification of topoisomerase I as the cytotoxic target of the protoberberine alkaloid coralyne

Cancer Research

Volumn 56, Issue 12, 1996, Pages 2795-2800

  Gatto, Barbara ^a   Sanders, Marilyn M ^a   Yu, Chiang ^a   Wu, Hong Yan ^a   Makhey, Darshan ^b   LaVoie, Edmond J ^b   Liu, Leroy F ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; CORALYNE; DNA TOPOISOMERASE; NITIDINE; PROTOBERBERINE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CROSS RESISTANCE; CYTOTOXICITY; DNA STRAND BREAKAGE; DRUG PROTEIN BINDING; ENZYME INDUCTION; ENZYME PURIFICATION; ESCHERICHIA COLI; HUMAN; HUMAN CELL; LEUKEMIA; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BASE SEQUENCE; BERBERINE ALKALOIDS; CAMPTOTHECIN; CATTLE; DNA DAMAGE; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MOLECULAR SEQUENCE DATA; PHENANTHRIDINES; YEASTS;

EID: 0029947975     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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