The role of rat serum carboxylesterase in the activation of paclitaxel and camptothecin prodrugs

Cancer Research

Volumn 56, Issue 7, 1996, Pages 1471-1474

  Senter, Peter D ^a   Marquardt, Hans ^a   Thomas, Beth A ^b   Hammock, Bruce D ^b   Frank, Ian S ^a   Svensson, Håkan P ^a  

^a BRISTOL MYERS SQUIBB   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; CARBOXYLESTERASE; IRINOTECAN; PACLITAXEL; PRODRUG;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVATION; DRUG BLOOD LEVEL; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; LUNG CARCINOMA; MELANOMA; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIOTRANSFORMATION; CAMPTOTHECIN; CARBOXYLESTERASE; CARBOXYLIC ESTER HYDROLASES; HUMANS; MICE; PACLITAXEL; PRODRUGS; RATS;

EID: 0029863926     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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