Conformational studies of paclitaxel analogs modified at the C-2' position in hydrophobic and hydrophilic solvent systems

Journal of Medicinal Chemistry

Volumn 40, Issue 20, 1997, Pages 3305-3311

  Moyna, G ^a   Williams, H J ^a   Scott, A I ^a   Ringel, I ^a   Gorodetsky, R ^a   Swindell, C S ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2' DEOXYPACLITAXEL; 2' METHOXYPACLITAXEL; PACLITAXEL DERIVATIVE; SOLVENT; TUBULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; CATTLE; CELL PROLIFERATION; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG CONFORMATION; FIBROSARCOMA; HUMAN; HUMAN CELL; HYDROGEN BOND; HYDROPHILICITY; HYDROPHOBICITY; MICROTUBULE ASSEMBLY; MOLECULAR MODEL; MOLECULAR RECOGNITION; NONHUMAN; NOTE; NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

ANIMALS; CATTLE; CELL DIVISION; CIRCULAR DICHROISM; HUMANS; MACROPHAGES; MICE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PACLITAXEL; SOLVENTS; TUMOR CELLS, CULTURED;

EID: 0030846178     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970026+     Document Type: Note

References (33)