-
1
-
-
84920291929
-
Novel anthracycline disaccharides: Effect of the orientation of the second sugar residue on antitumor activity
-
Animati, F., Arcamone, F., Bigioni, M., Berettoni, M., Cipollone, A., Franciotti, M., Lombardi, P., Pratesi, G., Supino, R. and Zunino, F. (1996a) Novel anthracycline disaccharides: effect of the orientation of the second sugar residue on antitumor activity. Ann. Oncol. 7 (Suppl. 1): 109.
-
(1996)
Ann. Oncol.
, vol.7
, Issue.SUPPL. 1
, pp. 109
-
-
Animati, F.1
Arcamone, F.2
Bigioni, M.3
Berettoni, M.4
Cipollone, A.5
Franciotti, M.6
Lombardi, P.7
Pratesi, G.8
Supino, R.9
Zunino, F.10
-
2
-
-
9544232513
-
Biochemical and pharmacological activity of novel 8-fluoroanthracyclines: Influence of stereochetnistry and conformation
-
Animati, F., Arcamone, F., Bigioni, M., Capranico, G., Caserini, C., De Cesare, M., Lombardi P., Pratesi, G., Salvatore, C., Supino, R. and Zunino, F. (1996b) Biochemical and pharmacological activity of novel 8-fluoroanthracyclines: influence of stereochetnistry and conformation. Mol. Pharmacol. 50: 603-609.
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 603-609
-
-
Animati, F.1
Arcamone, F.2
Bigioni, M.3
Capranico, G.4
Caserini, C.5
De Cesare, M.6
Lombardi, P.7
Pratesi, G.8
Salvatore, C.9
Supino, R.10
Zunino, F.11
-
3
-
-
33748904372
-
New anthracycline disaccharides. Synthesis of L-daunosaminyl-α(1-4)-2-deoxy-L-rhamnosyl and of L-daunosaminyl-α(1-4)-2-deoxy-L-fucosyl daunorubicin analogues
-
Animati, F., Berettoni, M., Cipollone, A., Franciotti, M., Lombardi, P., Monteagudo, E. and Arcamone, F. (1996c) New anthracycline disaccharides. Synthesis of L-daunosaminyl-α(1-4)-2-deoxy-L-rhamnosyl and of L-daunosaminyl-α(1-4)-2-deoxy-L-fucosyl daunorubicin analogues. J. Chem. Soc. Perkin. Trans. 1: 1327-1329.
-
(1996)
J. Chem. Soc. Perkin. Trans.
, vol.1
, pp. 1327-1329
-
-
Animati, F.1
Berettoni, M.2
Cipollone, A.3
Franciotti, M.4
Lombardi, P.5
Monteagudo, E.6
Arcamone, F.7
-
4
-
-
0000356472
-
Doxorubicin, anticancer antibiotics
-
de Stevens, G. (ed.) Academic Press, New York
-
Arcamone, F. (1981) Doxorubicin, anticancer antibiotics. In: Medicinal Chemistry Series, pp. 1-369, de Stevens, G. (ed.) Academic Press, New York.
-
(1981)
Medicinal Chemistry Series
, pp. 1-369
-
-
Arcamone, F.1
-
5
-
-
0014490968
-
Adriamycin (14-hydroxydaunorubicin) an antitumor antibiotic
-
Arcamone, F., Franceschi, G., Penco, S. and Selva, A. (1969) Adriamycin (14-hydroxydaunorubicin) an antitumor antibiotic. Tetrahedron Lett. 10: 1007-1010.
-
(1969)
Tetrahedron Lett.
, vol.10
, pp. 1007-1010
-
-
Arcamone, F.1
Franceschi, G.2
Penco, S.3
Selva, A.4
-
6
-
-
0030807646
-
A doxorubicin disaccharide analog: Apoptosis-related improvement of efficacy in vivo
-
in press
-
Arcamone, F., Animati, F., Berettoni, M., Bigioni, M., Capranico, G., Casazza, A. M., Caserini, C., Cipollone, A., De Cesare, M., Franciotti, M., Lombardi, P., Madami, A., Manzini, S., Monteagudo, E., Polizzi, D., Pratesi, G., Righetti, S. C., Salvatore, C., Supino, R. and Zunino, F. (1997) A doxorubicin disaccharide analog: apoptosis-related improvement of efficacy in vivo. J. Natl. Cancer Inst., in press.
-
(1997)
J. Natl. Cancer Inst.
-
-
Arcamone, F.1
Animati, F.2
Berettoni, M.3
Bigioni, M.4
Capranico, G.5
Casazza, A.M.6
Caserini, C.7
Cipollone, A.8
De Cesare, M.9
Franciotti, M.10
Lombardi, P.11
Madami, A.12
Manzini, S.13
Monteagudo, E.14
Polizzi, D.15
Pratesi, G.16
Righetti, S.C.17
Salvatore, C.18
Supino, R.19
Zunino, F.20
more..
-
7
-
-
0019802363
-
Approche de la synthèse d'anthracyclines oligosaccharidiques. Hemisynthèse de la 4′-O-(2-desoxy-L-fucosyl) daunorubicin
-
Boivin, J., Monneret, C. and Païs, M. (1981) Approche de la synthèse d'anthracyclines oligosaccharidiques. Hemisynthèse de la 4′-O-(2-desoxy-L-fucosyl) daunorubicin. Tetrahedron 37: 4219-4228.
-
(1981)
Tetrahedron
, vol.37
, pp. 4219-4228
-
-
Boivin, J.1
Monneret, C.2
Païs, M.3
-
8
-
-
0027181002
-
Drugs ten years later: Epirubicin
-
Bonadonna, G., Gianni, L., Santoro, A., Bonfante, V., Bidoli, P., Casali, P., Demicheli, R. and Valagussa, P. (1993) Drugs ten years later: epirubicin. Ann. Oncol. 4: 359-369.
-
(1993)
Ann. Oncol.
, vol.4
, pp. 359-369
-
-
Bonadonna, G.1
Gianni, L.2
Santoro, A.3
Bonfante, V.4
Bidoli, P.5
Casali, P.6
Demicheli, R.7
Valagussa, P.8
-
9
-
-
0000097143
-
Anthracyclinone und Anthracycline (Rhodomycinone, Pyrromycinone und lhre Glycoside)
-
Zeichmeister, L. (ed.) Springer, Vienna
-
Brockmann, H. (1963) Anthracyclinone und Anthracycline (Rhodomycinone, Pyrromycinone und lhre Glycoside). In: Fortschritte der Chemie Organischer Naturstoffe, Vol. 21, pp. 121-182, Zeichmeister, L. (ed.) Springer, Vienna.
-
(1963)
Fortschritte der Chemie Organischer Naturstoffe
, vol.21
, pp. 121-182
-
-
Brockmann, H.1
-
10
-
-
0002182396
-
Antitumor inhibitors of DNA topoisomerases
-
Capranico, G. and Zunino, F. (1995) Antitumor inhibitors of DNA topoisomerases. Curr. Pharm. Design 1: 1-14.
-
(1995)
Curr. Pharm. Design
, vol.1
, pp. 1-14
-
-
Capranico, G.1
Zunino, F.2
-
11
-
-
0024602758
-
Role of DNA breakage in cytotoxicity of doxorubicin, 9-deoxydoxorubicin, and 4-demethyl-6-deoxydoxorubicin in murine leukemia P388 cells
-
Capranico, G., De Isabella, P., Penco, S., Tinelli, S. and Zunico, F. (1989) Role of DNA breakage in cytotoxicity of doxorubicin, 9-deoxydoxorubicin, and 4-demethyl-6-deoxydoxorubicin in murine leukemia P388 cells. Cancer Res. 49: 2022-2027.
-
(1989)
Cancer Res.
, vol.49
, pp. 2022-2027
-
-
Capranico, G.1
De Isabella, P.2
Penco, S.3
Tinelli, S.4
Zunico, F.5
-
12
-
-
0025037693
-
Sequence-selective topoisomerase II inhibition by anthracycline derivatives in SV 40 DNA: Relationship with DNA binding affinity and cytotoxicity
-
Capranico, G., Zunino, F., Kohn, K. W. and Pommier, Y. (1990) Sequence-selective topoisomerase II inhibition by anthracycline derivatives in SV 40 DNA: relationship with DNA binding affinity and cytotoxicity. Biochemistry 29: 562-569.
-
(1990)
Biochemistry
, vol.29
, pp. 562-569
-
-
Capranico, G.1
Zunino, F.2
Kohn, K.W.3
Pommier, Y.4
-
13
-
-
0028304459
-
Influence of structural modifications at the 3′ and 4′ positions of doxorubicin on the drug ability to trap topoisomerase II and to overcome drug resistance
-
Capranico, G., Supino, R., Binaschi, M., Capolongo, L., Grandi, M., Suarato, A. and Zunino, F. (1994) Influence of structural modifications at the 3′ and 4′ positions of doxorubicin on the drug ability to trap topoisomerase II and to overcome drug resistance. Mol. Pharmacol. 45: 908-915.
-
(1994)
Mol. Pharmacol.
, vol.45
, pp. 908-915
-
-
Capranico, G.1
Supino, R.2
Binaschi, M.3
Capolongo, L.4
Grandi, M.5
Suarato, A.6
Zunino, F.7
-
14
-
-
0028814479
-
Change of the sequence specificity of daunorubicin-stimulated topoisomerase II DNA cleavage by epimerization of the amino group of the sugar moiety
-
Capranico, G., Butelli, E. and Zunino, F. (1995) Change of the sequence specificity of daunorubicin-stimulated topoisomerase II DNA cleavage by epimerization of the amino group of the sugar moiety. Cancer Res. 55: 312-317.
-
(1995)
Cancer Res.
, vol.55
, pp. 312-317
-
-
Capranico, G.1
Butelli, E.2
Zunino, F.3
-
15
-
-
0021258466
-
Separation, characterization, and analysis of epirubicin(4′-epidoxorubicin) and its metabolites from human urine
-
Cassinelli, G., Configliacchi, E., Penco, S., Rivola, G., Arcamone, F., Pacciarini, A. and Ferrari, L. (1984) Separation, characterization, and analysis of epirubicin(4′-epidoxorubicin) and its metabolites from human urine. Drug Metab. Dispos. 12: 506-510.
-
(1984)
Drug Metab. Dispos.
, vol.12
, pp. 506-510
-
-
Cassinelli, G.1
Configliacchi, E.2
Penco, S.3
Rivola, G.4
Arcamone, F.5
Pacciarini, A.6
Ferrari, L.7
-
16
-
-
0026516911
-
Idarubicin: An anthracycline antineoplastic agent
-
Cersosimo, R. J. (1992) Idarubicin: an anthracycline antineoplastic agent. Clin. Pharmacol. 11: 152-167.
-
(1992)
Clin. Pharmacol.
, vol.11
, pp. 152-167
-
-
Cersosimo, R.J.1
-
17
-
-
0016640250
-
DNA complexing antibiotics: Daunomycin, adriamycin and their derivatives
-
Di Marco, A. and Arcamone, F. (1974) DNA complexing antibiotics: daunomycin, adriamycin and their derivatives Arzneimittelforschung 25: 368-375.
-
(1974)
Arzneimittelforschung
, vol.25
, pp. 368-375
-
-
Di Marco, A.1
Arcamone, F.2
-
18
-
-
0017118358
-
Relationship between activity and aminosugar stereochemistry in daunorubicin and adriamycin derivatives
-
Di Marco, A., Casazza, A. M., Gambetta, R., Supino, R. and Zunino, F. (1976) Relationship between activity and aminosugar stereochemistry in daunorubicin and adriamycin derivatives. Cancer Res. 36: 1062-1966.
-
(1976)
Cancer Res.
, vol.36
, pp. 1062-1966
-
-
Di Marco, A.1
Casazza, A.M.2
Gambetta, R.3
Supino, R.4
Zunino, F.5
-
19
-
-
4243477646
-
Synthesis of 7-(3-amino-2,3,6,-trideoxy-4-O-(2,6-dideoxy-α-L-lyxo-hexopyranosyl)-α-L-lyxo-hexo pyranosyl) daunomycinone
-
El Khadem, H. S. and Matsuura D. (1982) Synthesis of 7-(3-amino-2,3,6,-trideoxy-4-O-(2,6-dideoxy-α-L-lyxo-hexopyranosyl)-α-L-lyxo-hexo pyranosyl) daunomycinone. Carbohydr. Res. 101: C1-C4.
-
(1982)
Carbohydr. Res.
, vol.101
-
-
El Khadem, H.S.1
Matsuura, D.2
-
20
-
-
0002265018
-
Protocols for screening chemical agents and natural products against animal tumors and other biological systems
-
Geran, R. I., Greenberg, N. H., Mcdonald, M. M., Schumacher, A. M. and Abbot, B. G. (1972) Protocols for screening chemical agents and natural products against animal tumors and other biological systems. Cancer Chemother. Rep. Part 33; -88.
-
(1972)
Cancer Chemother. Rep. Part 33
, vol.33
, pp. 88
-
-
Geran, R.I.1
Greenberg, N.H.2
Mcdonald, M.M.3
Schumacher, A.M.4
Abbot, B.G.5
-
21
-
-
0024595338
-
Correlation between growth inhibition and intranuclear coxorubicin and 4′-deoxy-4′-iododoxorubicin quantitated in living K562 cells by microspectrofluorometry
-
Gigli, M., Rasoanaivo, T. W., Millot, J.-M., Jeannesson, P., Rizzo, V., Jardillier, J.-C., Arcamone, F. and Manfait, M. (1989) Correlation between growth inhibition and intranuclear coxorubicin and 4′-deoxy-4′-iododoxorubicin quantitated in living K562 cells by microspectrofluorometry. Cancer Res. 49: 560-564.
-
(1989)
Cancer Res.
, vol.49
, pp. 560-564
-
-
Gigli, M.1
Rasoanaivo, T.W.2
Millot, J.-M.3
Jeannesson, P.4
Rizzo, V.5
Jardillier, J.-C.6
Arcamone, F.7
Manfait, M.8
-
22
-
-
0024602650
-
Joint experimental and theorethical investigation of the comparative DNA binding affinities of intercalating anthracycline derivatives
-
Gresh, N., Pullman, B., Arcamone, F., Menozzi, M. and Tonani, R. (1988) Joint experimental and theorethical investigation of the comparative DNA binding affinities of intercalating anthracycline derivatives. Mol. Pharmacol. 35: 251-256.
-
(1988)
Mol. Pharmacol.
, vol.35
, pp. 251-256
-
-
Gresh, N.1
Pullman, B.2
Arcamone, F.3
Menozzi, M.4
Tonani, R.5
-
23
-
-
0028555349
-
Characterization of the Streptomyces peucetius ATCC 29050 genes encoding doxorubicin polyketide synthase
-
Grimm, A., Madduri, K., Ali, A. and Hutchinson, C. R. (1994) Characterization of the Streptomyces peucetius ATCC 29050 genes encoding doxorubicin polyketide synthase. Gene 151: 1-10.
-
(1994)
Gene
, vol.151
, pp. 1-10
-
-
Grimm, A.1
Madduri, K.2
Ali, A.3
Hutchinson, C.R.4
-
24
-
-
0027362076
-
Synthesis and antiturnor activity of anthracycline disaccharide glycosides containing daunosamine
-
Horton, D., Priebe, W., Sznaidman, M. L. and Varela, O. (1993) Synthesis and antiturnor activity of anthracycline disaccharide glycosides containing daunosamine. J. Antibiot. 46: 1720-1730.
-
(1993)
J. Antibiot.
, vol.46
, pp. 1720-1730
-
-
Horton, D.1
Priebe, W.2
Sznaidman, M.L.3
Varela, O.4
-
25
-
-
0029433862
-
Synthesis and conformational preference of novel 8-fluoroanthracyclines
-
Lombardi, P., Animati, F., Cipollone, A., Giannini, G., Monteagudo, E. and Arcamone, F. (1995) Synthesis and conformational preference of novel 8-fluoroanthracyclines. Acta Biochim. Pol. 42: 433-444.
-
(1995)
Acta Biochim. Pol.
, vol.42
, pp. 433-444
-
-
Lombardi, P.1
Animati, F.2
Cipollone, A.3
Giannini, G.4
Monteagudo, E.5
Arcamone, F.6
-
26
-
-
0030995769
-
Conformational analysis of 4-demethoxy-7-O-[2,6-dideoxy-4-O-(2,3,6-trideoxy-3-amino-α-L-lyxo-hexopyranosyl)-α-L-lyxo-hexo pyranosyl] adriamycinone, the first doxorubicin disaccharide analogue to be reported
-
Monteagudo, E., Madami, A., Animati, F., Lombardi, P. and Arcamone, F. (1997) Conformational analysis of 4-demethoxy-7-O-[2,6-dideoxy-4-O-(2,3,6-trideoxy-3-amino-α-L-lyxo-hexopyranosyl)-α-L-lyxo-hexo pyranosyl] adriamycinone, the first doxorubicin disaccharide analogue to be reported. Carbohydr. Res. 300: 11-16.
-
(1997)
Carbohydr. Res.
, vol.300
, pp. 11-16
-
-
Monteagudo, E.1
Madami, A.2
Animati, F.3
Lombardi, P.4
Arcamone, F.5
-
27
-
-
0024399696
-
DNA-drug interactions: The crystal structure of d(CGATCG) complexed with daunomycin
-
Moore, M. H., Hunter, W. N., Langlois d'Estanoit, B. and Kennard, O. (1989) DNA-drug interactions: the crystal structure of d(CGATCG) complexed with daunomycin. J. Mol. Biol. 206: 693-705.
-
(1989)
J. Mol. Biol.
, vol.206
, pp. 693-705
-
-
Moore, M.H.1
Hunter, W.N.2
Langlois D'Estanoit, B.3
Kennard, O.4
-
28
-
-
0029656011
-
Synthesis of ring A fluorinated anthracyclines
-
Pasqui, F., Canfarini, F., Giolitti, A., Guidi, A., Pestellini, V. and Arcamone, F. (1996) Synthesis of ring A fluorinated anthracyclines. Tetrahedron 52: 185-198.
-
(1996)
Tetrahedron
, vol.52
, pp. 185-198
-
-
Pasqui, F.1
Canfarini, F.2
Giolitti, A.3
Guidi, A.4
Pestellini, V.5
Arcamone, F.6
-
29
-
-
0002373164
-
Synthesis and ring A conformation of new anthracyclines
-
Penco, S., Angelucci, F., Ballabio, M., Barchielli, G., Suarato, A., Vanotti, E., Vogevani, A. and Arcamone, F. (1984) Synthesis and ring A conformation of new anthracyclines. Heterocycles 21: 21-27.
-
(1984)
Heterocycles
, vol.21
, pp. 21-27
-
-
Penco, S.1
Angelucci, F.2
Ballabio, M.3
Barchielli, G.4
Suarato, A.5
Vanotti, E.6
Vogevani, A.7
Arcamone, F.8
-
30
-
-
0000420523
-
DNA topoisomerase II inhibitors
-
Techter, B. A. (ed.) Humana Press, Totowa
-
Pommier, Y. (1997) DNA topoisomerase II inhibitors. In: Cancer Therapeutics, Experimental and Clinical Agents, pp. 153-174, Techter, B. A. (ed.) Humana Press, Totowa.
-
(1997)
Cancer Therapeutics, Experimental and Clinical Agents
, pp. 153-174
-
-
Pommier, Y.1
-
31
-
-
0000225064
-
Antitumor activity of [L-daunosaminyl-α-(1-4)-2-deoxy-α-L-fucosyl]-4-demethoxy-adriamycinone (MEN 10755) in a panel of human tumor xenografts naturally resistant to doxorubicin
-
Pratesi, G., Animati, F., Arcamone, F., Berettoni, M., Bigioni, M., Cipollone, A., Franciotti, M., Lombardi, P., Supino, R. and Zunino, F. (1996a) Antitumor activity of [L-daunosaminyl-α-(1-4)-2-deoxy-α-L-fucosyl]-4-demethoxy-adriamycinone (MEN 10755) in a panel of human tumor xenografts naturally resistant to doxorubicin. Proc. Am. Assoc. Cancer Res. 37: 394.
-
(1996)
Proc. Am. Assoc. Cancer Res.
, vol.37
, pp. 394
-
-
Pratesi, G.1
Animati, F.2
Arcamone, F.3
Berettoni, M.4
Bigioni, M.5
Cipollone, A.6
Franciotti, M.7
Lombardi, P.8
Supino, R.9
Zunino, F.10
-
32
-
-
84920299554
-
Pharmacological properties of novel anthracycline aminodisaccharide in human lung and gynecological cancer. Preclinical studies
-
Pratesi, G., Bigioni, M., De Casare, M., Supino, R., Zunino F., Animati, F., Arcamone, F., Berettoni, M., Cipollone, A., Franciotti, M. and Lombardi, P. (1996b) Pharmacological properties of novel anthracycline aminodisaccharide in human lung and gynecological cancer. Preclinical studies. Ann. Oncol. 7 (Suppl. 1): 41.
-
(1996)
Ann. Oncol.
, vol.7
, Issue.SUPPL. 1
, pp. 41
-
-
Pratesi, G.1
Bigioni, M.2
De Casare, M.3
Supino, R.4
Zunino, F.5
Animati, F.6
Arcamone, F.7
Berettoni, M.8
Cipollone, A.9
Franciotti, M.10
Lombardi, P.11
-
33
-
-
0021151237
-
Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II
-
Tewey, K. M., Rowe, T. C., Yang, L., Halligan, B. D. and Liu, L. F. (1984) Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II. Science 226: 466-468.
-
(1984)
Science
, vol.226
, pp. 466-468
-
-
Tewey, K.M.1
Rowe, T.C.2
Yang, L.3
Halligan, B.D.4
Liu, L.F.5
-
34
-
-
0023151436
-
Interactions between an anthracycline antibiotic and DNA: Molecular structure of daunomycin complex to d(CpGpTpApCpGp) at 1.2 Å resolution
-
Wang, A. H.-J., Ughetto, G., Quigley, G. J. and Rich, A. (1987) Interactions between an anthracycline antibiotic and DNA: molecular structure of daunomycin complex to d(CpGpTpApCpGp) at 1.2 Å resolution. Biochemistry 26: 1152-1163.
-
(1987)
Biochemistry
, vol.26
, pp. 1152-1163
-
-
Wang, A.H.-J.1
Ughetto, G.2
Quigley, G.J.3
Rich, A.4
-
35
-
-
0026714331
-
The anthracyclines: Will we ever find a better doxorubicin?
-
Weiss, R. B. (1992) The anthracyclines: will we ever find a better doxorubicin? Semin. Oncol. 19: 670-686.
-
(1992)
Semin. Oncol.
, vol.19
, pp. 670-686
-
-
Weiss, R.B.1
|