Syntheses and structure-activity relationships of the second-generation antitumor taxoids: Exceptional activity against drug-resistant cancer cells

Journal of Medicinal Chemistry

Volumn 39, Issue 20, 1996, Pages 3889-3896

  Ojima, Iwao ^a   Slater, John C ^a   Michaud, Evelyne ^a   Kuduk, Scott D ^a   Bounaud, Pierre Yves ^a   Vrignaud, Patricia ^b   Bissery, Marie Christine ^b   Veith, Jean M ^c   Pera, Paula ^c   Bernacki, Ralph J ^c  

^a STONY BROOK UNIVERSITY   (United States)

^b SANOFI   (France)

^c ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOCETAXEL; GLYCOPROTEIN P; PACLITAXEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CANCER CONTROL; CELL KILLING; COLON CANCER; DRUG ACTIVITY; INTRAVENOUS DRUG ADMINISTRATION; LUNG NON SMALL CELL CANCER; MELANOMA; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; OVARY CANCER; PHENOTYPE; PROTEIN BINDING; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BREAST NEOPLASMS; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; MELANOMA, EXPERIMENTAL; MICE; MICE, NUDE; MOLECULAR STRUCTURE; OVARIAN NEOPLASMS; P-GLYCOPROTEIN; PACLITAXEL; STRUCTURE-ACTIVITY RELATIONSHIP; TAXOIDS; TUMOR CELLS, CULTURED;

EID: 10144251769     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9604080     Document Type: Article

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