Structure-activity relationship for DNA topoisomerase II-induced DNA cleavage by azatoxin analogues

Bioorganic and Medicinal Chemistry

Volumn 5, Issue 9, 1997, Pages 1807-1815

  Madalengoitia, Jose S ^a   Tepe, Jetze J ^a   Werbovetz, Karl A ^a   Lehnert, Erich K ^a   Macdonald, Timothy L ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZATOXIN DERIVATIVE; DNA TOPOISOMERASE (ATP HYDROLYSING); ELLIPTICINE DERIVATIVE; EPIPODOPHYLLOTOXIN DERIVATIVE; ETOPOSIDE; UNCLASSIFIED DRUG;

ARTICLE; DNA CLEAVAGE; DNA STRAND; DRUG ACTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN TISSUE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION;

DNA; DNA TOPOISOMERASES, TYPE II; HYDROLYSIS; INDOLES; MAGNETIC RESONANCE SPECTROSCOPY; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030880552     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(97)00113-2     Document Type: Article

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