Quality Control in the Endoplasmic Reticulum: Crosstalk between ERAD and UPR pathways

Trends in Biochemical Sciences

Volumn 43, Issue 8, 2018, Pages 593-605

  Hwang, Jiwon ^a   Qi, Ling ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

endoplasmic reticulum (ER); ER chaperones; IRE1 ; protein degradation; protein folding; SEL1L HRD1

Indexed keywords

HEAT SHOCK PROTEIN 47; MEMBRANE PROTEIN; PROTEIN ERDJ4; PROTEIN HRD1; PROTEIN IRE1; PROTEIN IRE1 ALPHA; PROTEIN SEL1L; UNCLASSIFIED DRUG; CHAPERONE; DNAJB9 PROTEIN, HUMAN; ERN1 PROTEIN, HUMAN; HEAT SHOCK PROTEIN 40; PROTEIN; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE; SEL1L PROTEIN, HUMAN; SYVN1 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATION; FEEDBACK SYSTEM; HETEROZYGOSITY; HOMEOSTASIS; HUMAN; LOSS OF FUNCTION MUTATION; MOLECULAR INTERACTION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN FUNCTION; QUALITY CONTROL; REVIEW; UNFOLDED PROTEIN RESPONSE; CYTOSOL; ENDOPLASMIC RETICULUM; METABOLISM; SIGNAL TRANSDUCTION;

CYTOSOL; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM-ASSOCIATED DEGRADATION; ENDORIBONUCLEASES; HSP40 HEAT-SHOCK PROTEINS; HSP47 HEAT-SHOCK PROTEINS; MEMBRANE PROTEINS; MOLECULAR CHAPERONES; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; QUALITY CONTROL; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES; UNFOLDED PROTEIN RESPONSE;

EID: 85049353118     PISSN: 09680004     EISSN: 13624326     Source Type: Journal    
DOI: 10.1016/j.tibs.2018.06.005     Document Type: Review

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