Activation of the Unfolded Protein Response by Lipid Bilayer Stress

Molecular Cell

Volumn 67, Issue 4, 2017, Pages 673-684.e8

  Halbleib, Kristina ^a   Pesek, Kristina ^a   Covino, Roberto ^b   Hofbauer, Harald F ^a   Wunnicke, Dorith ^a   Hänelt, Inga ^a   Hummer, Gerhard ^a,b   Ernst, Robert ^a,c  

^a GOETHE UNIVERSITY   (Germany)

^b MAX PLANCK INSTITUTE OF BIOPHYSICS   (Germany)

^c SAARLAND UNIVERSITY   (Germany)

Author keywords

ER stress; Ire1; lipid bilayer stress; membrane quality control; membrane stress; membrane stress response; UPR

Indexed keywords

PROTEIN IRE1; IRE1 PROTEIN, S CEREVISIAE; LIPID BILAYER; MEMBRANE PROTEIN; PROTEIN SERINE THREONINE KINASE; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; ENDOPLASMIC RETICULUM STRESS; IN VITRO STUDY; IN VIVO STUDY; LIPID BILAYER; MOLECULAR DYNAMICS; NONHUMAN; OLIGOMERIZATION; PHYSICAL CHEMISTRY; PROTEIN FUNCTION; UNFOLDED PROTEIN RESPONSE; ALPHA HELIX; CHEMISTRY; ENDOPLASMIC RETICULUM; GENETICS; INTRACELLULAR MEMBRANE; METABOLISM; MUTATION; PROTEIN FOLDING; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; TIME FACTOR;

ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; INTRACELLULAR MEMBRANES; LIPID BILAYERS; MEMBRANE GLYCOPROTEINS; MOLECULAR DYNAMICS SIMULATION; MUTATION; PROTEIN CONFORMATION, ALPHA-HELICAL; PROTEIN FOLDING; PROTEIN-SERINE-THREONINE KINASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS; UNFOLDED PROTEIN RESPONSE;

EID: 85021810677     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2017.06.012     Document Type: Article

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