Degradation of a mutant secretory protein, α 1-antitrypsin Z, in the endoplasmic reticulum requires proteasome activity

Journal of Biological Chemistry

Volumn 271, Issue 37, 1996, Pages 22791-22795

  Qu, Dongfeng ^a   Teckman, Jeffrey H ^a   Omura, Satoshi ^b   Perlmutter, David H ^a  

^a ST LOUIS CHILDREN S HOSPITAL   (United States)

^b KITASATO INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; CALNEXIN; COMPLEMENTARY DNA; ENDONUCLEASE; MESSENGER RNA; MICROSOME ENZYME; MUTANT PROTEIN; PROTEASOME; PROTEINASE; SECRETORY PROTEIN;

ALPHA 1 ANTITRYPSIN DEFICIENCY; ARTICLE; EMPHYSEMA; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; FIBROBLAST; LIVER DISEASE; MICROSOME; PANCREAS; PRIORITY JOURNAL;

ACETYLCYSTEINE; ALPHA 1-ANTITRYPSIN; ANIMALS; CALCIUM-BINDING PROTEINS; CALNEXIN; CELL-FREE SYSTEM; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DOGS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOPEPTIDASE K; ENDOPLASMIC RETICULUM; FIBROBLASTS; HEXOSAMINIDASES; HUMANS; MULTIENZYME COMPLEXES; PROTEASOME ENDOPEPTIDASE COMPLEX; RABBITS;

EID: 0029788023     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.37.22791     Document Type: Article

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