The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity

Nature Communications

Volumn 7, Issue , 2016, Pages

  Xu, Yuanming ^a   Zhao, Fang ^a   Qiu, Quan ^a,b   Chen, Kun ^b   Wei, Juncheng ^a   Kong, Qingfei ^a   Gao, Beixue ^a   Melo Cardenas, Johanna ^a   Zhang, Bin ^a   Zhang, Jinping ^c   Song, Jianxun ^d   Zhang, Donna D ^e   Zhang, Jianing ^f   Fan, Yunping ^g   Li, Huabin ^b,g   Fang, Deyu ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b FUDAN UNIVERSITY   (China)

^c SOOCHOW UNIVERSITY   (China)

^d PENN STATE COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF ARIZONA   (United States)

^f DALIAN UNIVERSITY OF TECHNOLOGY   (China)

^g SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 2; UBIQUITIN LIGASE HRD1; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; CDKN1B PROTEIN, MOUSE; SYVN1 PROTEIN, HUMAN; SYVN1 PROTEIN, MOUSE;

AMINO ACID; CELLS AND CELL COMPONENTS; DISEASE; ENZYME; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC DIFFERENTIATION; IMMUNE SYSTEM; IMMUNITY; MEMBRANE; MUTATION; RODENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOPLASMIC RETICULUM MEMBRANE; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; GENE DELETION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH17 CELL; UBIQUITINATION; ANIMAL; ENDOPLASMIC RETICULUM; GENETICS; IMMUNOLOGY; INTRACELLULAR MEMBRANE; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; METABOLISM; T LYMPHOCYTE; TRANSGENIC MOUSE;

MUS;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CYCLIN-DEPENDENT KINASE INHIBITOR P27; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENDOPLASMIC RETICULUM; HUMANS; INTRACELLULAR MEMBRANES; LYMPHOCYTE ACTIVATION; MICE, KNOCKOUT; MICE, TRANSGENIC; MULTIPLE SCLEROSIS; T-LYMPHOCYTES; TH1 CELLS; TH17 CELLS; UBIQUITIN-PROTEIN LIGASES;

EID: 84978760294     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms12073     Document Type: Article

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