-
1
-
-
84870733168
-
Protein folding in the endoplasmic reticulum
-
Braakman, I., Hebert, D.N., Protein folding in the endoplasmic reticulum. Cold Spring Harb. Perspect. Biol., 5, 2013, a013201.
-
(2013)
Cold Spring Harb. Perspect. Biol.
, vol.5
, pp. a013201
-
-
Braakman, I.1
Hebert, D.N.2
-
2
-
-
84860118506
-
The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology
-
Guerriero, C.J., Brodsky, J.L., The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology. Physiol. Rev. 92 (2012), 537–576.
-
(2012)
Physiol. Rev.
, vol.92
, pp. 537-576
-
-
Guerriero, C.J.1
Brodsky, J.L.2
-
3
-
-
84856111924
-
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
-
Hetz, C., The unfolded protein response: controlling cell fate decisions under ER stress and beyond. Nat. Rev. Mol. Cell Biol. 13 (2012), 89–102.
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 89-102
-
-
Hetz, C.1
-
4
-
-
80052366845
-
Stressed out about obesity: IRE1alpha-XBP1 in metabolic disorders
-
Sha, H., et al. Stressed out about obesity: IRE1alpha-XBP1 in metabolic disorders. Trends Endocrinol. Metab. 22 (2011), 374–381.
-
(2011)
Trends Endocrinol. Metab.
, vol.22
, pp. 374-381
-
-
Sha, H.1
-
5
-
-
20044394518
-
Essential role of synoviolin in embryogenesis
-
Yagishita, N., et al. Essential role of synoviolin in embryogenesis. J. Biol. Chem. 280 (2005), 7909–7916.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 7909-7916
-
-
Yagishita, N.1
-
6
-
-
77951564358
-
Deficiency of suppressor enhancer lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethality
-
Francisco, A.B., et al. Deficiency of suppressor enhancer lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethality. J. Biol. Chem. 285 (2010), 13694–13703.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 13694-13703
-
-
Francisco, A.B.1
-
7
-
-
33846506651
-
Targeted deletion of p97 (VCP/CDC48) in mouse results in early embryonic lethality
-
Müller, J.M., et al. Targeted deletion of p97 (VCP/CDC48) in mouse results in early embryonic lethality. Biochem. Biophys. Res. Commun. 354 (2007), 459–465.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.354
, pp. 459-465
-
-
Müller, J.M.1
-
8
-
-
84896270715
-
Quality control: ER-associated degradation: protein quality control and beyond
-
Ruggiano, A., et al. Quality control: ER-associated degradation: protein quality control and beyond. J. Cell. Biol. 204 (2014), 869–879.
-
(2014)
J. Cell. Biol.
, vol.204
, pp. 869-879
-
-
Ruggiano, A.1
-
9
-
-
84898729879
-
Cleaning up in the endoplasmic reticulum: ubiquitin in charge
-
Christianson, J.C., Ye, Y., Cleaning up in the endoplasmic reticulum: ubiquitin in charge. Nat. Struct. Mol. Biol. 21 (2014), 325–335.
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 325-335
-
-
Christianson, J.C.1
Ye, Y.2
-
10
-
-
84979077635
-
Endoplasmic reticulum-associated degradation and lipid homeostasis
-
Stevenson, J., et al. Endoplasmic reticulum-associated degradation and lipid homeostasis. Annu. Rev. Nutr. 36 (2016), 511–542.
-
(2016)
Annu. Rev. Nutr.
, vol.36
, pp. 511-542
-
-
Stevenson, J.1
-
11
-
-
84913536702
-
The ER-associated degradation adaptor protein Sel1L regulates LPL secretion and lipid metabolism
-
Sha, H., et al. The ER-associated degradation adaptor protein Sel1L regulates LPL secretion and lipid metabolism. Cell Metab. 20 (2014), 458–470.
-
(2014)
Cell Metab.
, vol.20
, pp. 458-470
-
-
Sha, H.1
-
12
-
-
84893517295
-
Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival
-
Sun, S., et al. Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival. Proc. Natl. Acad. Sci. U. S. A. 111 (2014), E582–E591.
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. E582-E591
-
-
Sun, S.1
-
13
-
-
84948712979
-
IRE1a is an endogenous substrate of endoplasmic-reticulum-associated degradation
-
Sun, S., et al. IRE1a is an endogenous substrate of endoplasmic-reticulum-associated degradation. Nat. Cell Biol. 17 (2015), 1546–1555.
-
(2015)
Nat. Cell Biol.
, vol.17
, pp. 1546-1555
-
-
Sun, S.1
-
14
-
-
84956634517
-
Epithelial Sel1L is required for the maintenance of intestinal homeostasis
-
Sun, S., et al. Epithelial Sel1L is required for the maintenance of intestinal homeostasis. Mol. Biol. Cell 27 (2016), 483–490.
-
(2016)
Mol. Biol. Cell
, vol.27
, pp. 483-490
-
-
Sun, S.1
-
15
-
-
84898874270
-
Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis
-
Wu, T., et al. Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis. Genes Dev. 28 (2014), 708–722.
-
(2014)
Genes Dev.
, vol.28
, pp. 708-722
-
-
Wu, T.1
-
16
-
-
84911924274
-
Hrd1-mediated BLIMP-1 ubiquitination promotes dendritic cell MHCII expression for CD4 T cell priming during inflammation
-
Yang, H., et al. Hrd1-mediated BLIMP-1 ubiquitination promotes dendritic cell MHCII expression for CD4 T cell priming during inflammation. J. Exp. Med. 211 (2014), 2467–2479.
-
(2014)
J. Exp. Med.
, vol.211
, pp. 2467-2479
-
-
Yang, H.1
-
17
-
-
84927698900
-
The E3 ligase synoviolin controls body weight and mitochondrial biogenesis through negative regulation of PGC-1beta
-
Fujita, H., et al. The E3 ligase synoviolin controls body weight and mitochondrial biogenesis through negative regulation of PGC-1beta. EMBO J. 34 (2015), 1042–1055.
-
(2015)
EMBO J.
, vol.34
, pp. 1042-1055
-
-
Fujita, H.1
-
18
-
-
0028840915
-
Degradation of CFTR by the ubiquitin-proteasome pathway
-
Ward, C.L., et al. Degradation of CFTR by the ubiquitin-proteasome pathway. Cell 83 (1995), 121–127.
-
(1995)
Cell
, vol.83
, pp. 121-127
-
-
Ward, C.L.1
-
19
-
-
0028006681
-
Intracellular turnover of cystic fibrosis transmembrane conductance regulator. Inefficient processing and rapid degradation of wild-type and mutant proteins
-
Ward, C.L., Kopito, R.R., Intracellular turnover of cystic fibrosis transmembrane conductance regulator. Inefficient processing and rapid degradation of wild-type and mutant proteins. J. Biol. Chem. 269 (1994), 25710–25718.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 25710-25718
-
-
Ward, C.L.1
Kopito, R.R.2
-
20
-
-
0028559511
-
Conformational maturation of CFTR but not its mutant counterpart (delta F508) occurs in the endoplasmic reticulum and requires ATP
-
Lukacs, G.L., et al. Conformational maturation of CFTR but not its mutant counterpart (delta F508) occurs in the endoplasmic reticulum and requires ATP. EMBO J. 13 (1994), 6076–6086.
-
(1994)
EMBO J.
, vol.13
, pp. 6076-6086
-
-
Lukacs, G.L.1
-
21
-
-
0029811218
-
Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein
-
Hampton, R.Y., et al. Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein. Mol. Biol. Cell 7 (1996), 2029–2044.
-
(1996)
Mol. Biol. Cell
, vol.7
, pp. 2029-2044
-
-
Hampton, R.Y.1
-
22
-
-
0034597161
-
Endoplasmic reticulum degradation requires lumen to cytosol signaling. Transmembrane control of Hrd1p by Hrd3p
-
Gardner, R.G., et al. Endoplasmic reticulum degradation requires lumen to cytosol signaling. Transmembrane control of Hrd1p by Hrd3p. J. Cell Biol. 151 (2000), 69–82.
-
(2000)
J. Cell Biol.
, vol.151
, pp. 69-82
-
-
Gardner, R.G.1
-
23
-
-
0035144199
-
Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation
-
Bays, N.W., et al. Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation. Nat. Cell Biol. 3 (2001), 24–29.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 24-29
-
-
Bays, N.W.1
-
24
-
-
0034971386
-
In vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation
-
Gardner, R.G., et al. In vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation. Mol. Cell Biol. 21 (2001), 4276–4291.
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 4276-4291
-
-
Gardner, R.G.1
-
25
-
-
0032957204
-
Biosynthesis and degradation of CFTR
-
Kopito, R.R., Biosynthesis and degradation of CFTR. Physiol. Rev. 79 (1999), S167–S173.
-
(1999)
Physiol. Rev.
, vol.79
, pp. S167-S173
-
-
Kopito, R.R.1
-
26
-
-
84870763849
-
The mammalian endoplasmic reticulum-associated degradation system
-
Olzmann, J.A., et al. The mammalian endoplasmic reticulum-associated degradation system. Cold Spring Harb. Perspect. Biol., 5, 2013, a013185.
-
(2013)
Cold Spring Harb. Perspect. Biol.
, vol.5
, pp. a013185
-
-
Olzmann, J.A.1
-
27
-
-
84931565973
-
N-linked sugar-regulated protein folding and quality control in the ER
-
Tannous, A., et al. N-linked sugar-regulated protein folding and quality control in the ER. Semin. Cell Dev. Biol. 41 (2015), 79–89.
-
(2015)
Semin. Cell Dev. Biol.
, vol.41
, pp. 79-89
-
-
Tannous, A.1
-
28
-
-
84870762133
-
The endoplasmic reticulum-associated degradation pathways of budding yeast
-
Thibault, G., Ng, D.T., The endoplasmic reticulum-associated degradation pathways of budding yeast. Cold Spring Harb. Perspect. Biol., 4, 2012, a013193.
-
(2012)
Cold Spring Harb. Perspect. Biol.
, vol.4
, pp. a013193
-
-
Thibault, G.1
Ng, D.T.2
-
29
-
-
40249088336
-
OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD
-
Christianson, J.C., et al. OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD. Nat. Cell Biol. 10 (2008), 272–282.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 272-282
-
-
Christianson, J.C.1
-
30
-
-
84970979593
-
Forcible destruction of severely misfolded mammalian glycoproteins by the non-glycoprotein ERAD pathway
-
Ninagawa, S., et al. Forcible destruction of severely misfolded mammalian glycoproteins by the non-glycoprotein ERAD pathway. J. Cell Biol. 211 (2015), 775–784.
-
(2015)
J. Cell Biol.
, vol.211
, pp. 775-784
-
-
Ninagawa, S.1
-
31
-
-
24944583185
-
Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen
-
Bhamidipati, A., et al. Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen. Mol. Cell 19 (2005), 741–751.
-
(2005)
Mol. Cell
, vol.19
, pp. 741-751
-
-
Bhamidipati, A.1
-
32
-
-
24944552879
-
Yos9p detects and targets misfolded glycoproteins for ER-associated degradation
-
Kim, W., et al. Yos9p detects and targets misfolded glycoproteins for ER-associated degradation. Mol. Cell 19 (2005), 753–764.
-
(2005)
Mol. Cell
, vol.19
, pp. 753-764
-
-
Kim, W.1
-
33
-
-
0037470410
-
Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle
-
Molinari, M., et al. Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle. Science 299 (2003), 1397–1400.
-
(2003)
Science
, vol.299
, pp. 1397-1400
-
-
Molinari, M.1
-
34
-
-
0037470515
-
EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin
-
Oda, Y., et al. EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin. Science 299 (2003), 1394–1397.
-
(2003)
Science
, vol.299
, pp. 1394-1397
-
-
Oda, Y.1
-
35
-
-
1842409617
-
Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation
-
Plemper, R.K., et al. Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation. Nature 388 (1997), 891–895.
-
(1997)
Nature
, vol.388
, pp. 891-895
-
-
Plemper, R.K.1
-
36
-
-
66449136067
-
EDEM1 recognition and delivery of misfolded proteins to the SEL1L-containing ERAD complex
-
Cormier, J.H., et al. EDEM1 recognition and delivery of misfolded proteins to the SEL1L-containing ERAD complex. Mol. Cell 34 (2009), 627–633.
-
(2009)
Mol. Cell
, vol.34
, pp. 627-633
-
-
Cormier, J.H.1
-
37
-
-
84255169603
-
Defining human ERAD networks through an integrative mapping strategy
-
Christianson, J.C., et al. Defining human ERAD networks through an integrative mapping strategy. Nat. Cell Biol. 14 (2012), 93–105.
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 93-105
-
-
Christianson, J.C.1
-
38
-
-
33750359201
-
SEL1L, the homologue of yeast Hrd3p, is involved in protein dislocation from the mammalian ER
-
Mueller, B., et al. SEL1L, the homologue of yeast Hrd3p, is involved in protein dislocation from the mammalian ER. J. Cell Biol. 175 (2006), 261–270.
-
(2006)
J. Cell Biol.
, vol.175
, pp. 261-270
-
-
Mueller, B.1
-
39
-
-
26244431960
-
Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane
-
Lilley, B.N., Ploegh, H.L., Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane. Proc. Natl. Acad. Sci. U. S. A. 102 (2005), 14296–14301.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 14296-14301
-
-
Lilley, B.N.1
Ploegh, H.L.2
-
40
-
-
50449107542
-
SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins
-
Mueller, B., et al. SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins. Proc. Natl. Acad. Sci. U. S. A. 105 (2008), 12325–12330.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 12325-12330
-
-
Mueller, B.1
-
41
-
-
78149482323
-
Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p
-
Carvalho, P., et al. Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p. Cell 143 (2010), 579–591.
-
(2010)
Cell
, vol.143
, pp. 579-591
-
-
Carvalho, P.1
-
42
-
-
84978435047
-
Autoubiquitination of the Hrd1 ligase triggers protein retrotranslocation in ERAD
-
Baldridge, R.D., Rapoport, T.A., Autoubiquitination of the Hrd1 ligase triggers protein retrotranslocation in ERAD. Cell 166 (2016), 394–407.
-
(2016)
Cell
, vol.166
, pp. 394-407
-
-
Baldridge, R.D.1
Rapoport, T.A.2
-
43
-
-
84908072286
-
Key steps in ERAD of luminal ER proteins reconstituted with purified components
-
Stein, A., et al. Key steps in ERAD of luminal ER proteins reconstituted with purified components. Cell 158 (2014), 1375–1388.
-
(2014)
Cell
, vol.158
, pp. 1375-1388
-
-
Stein, A.1
-
44
-
-
84948978497
-
gp78 functions downstream of Hrd1 to promote degradation of misfolded proteins of the endoplasmic reticulum
-
Zhang, T., et al. gp78 functions downstream of Hrd1 to promote degradation of misfolded proteins of the endoplasmic reticulum. Mol. Biol. Cell 26 (2015), 4438–4450.
-
(2015)
Mol. Biol. Cell
, vol.26
, pp. 4438-4450
-
-
Zhang, T.1
-
45
-
-
0027435169
-
Suppressors of a lin-12 hypomorph define genes that interact with both lin-12 and glp-1 in Caenorhabditis elegans
-
Sundaram, M., Greenwald, I., Suppressors of a lin-12 hypomorph define genes that interact with both lin-12 and glp-1 in Caenorhabditis elegans. Genetics 135 (1993), 765–783.
-
(1993)
Genetics
, vol.135
, pp. 765-783
-
-
Sundaram, M.1
Greenwald, I.2
-
46
-
-
84957812679
-
Crystal structure of SEL1L: insight into the roles of SLR motifs in ERAD pathway
-
Jeong, H., et al. Crystal structure of SEL1L: insight into the roles of SLR motifs in ERAD pathway. Sci. Rep., 6, 2016, 20261.
-
(2016)
Sci. Rep.
, vol.6
, pp. 20261
-
-
Jeong, H.1
-
47
-
-
79952433637
-
Processing and turnover of the Hedgehog protein in the endoplasmic reticulum
-
Chen, X., et al. Processing and turnover of the Hedgehog protein in the endoplasmic reticulum. J. Cell Biol. 192 (2011), 825–838.
-
(2011)
J. Cell Biol.
, vol.192
, pp. 825-838
-
-
Chen, X.1
-
48
-
-
84871197818
-
Unassembled CD147 is an endogenous endoplasmic reticulum-associated degradation substrate
-
Tyler, R.E., et al. Unassembled CD147 is an endogenous endoplasmic reticulum-associated degradation substrate. Mol. Biol. Cell 23 (2012), 4668–4678.
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 4668-4678
-
-
Tyler, R.E.1
-
49
-
-
84887058388
-
The unfolded protein response transducer ATF6 represents a novel transmembrane-type endoplasmic reticulum-associated degradation substrate requiring both mannose trimming and SEL1L protein
-
Horimoto, S., et al. The unfolded protein response transducer ATF6 represents a novel transmembrane-type endoplasmic reticulum-associated degradation substrate requiring both mannose trimming and SEL1L protein. J. Biol. Chem. 288 (2013), 31517–31527.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 31517-31527
-
-
Horimoto, S.1
-
50
-
-
79955758729
-
SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates
-
Iida, Y., et al. SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates. J. Biol. Chem. 286 (2011), 16929–16939.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 16929-16939
-
-
Iida, Y.1
-
51
-
-
84875204546
-
The ERdj5-Sel1L complex facilitates cholera toxin retrotranslocation
-
Williams, J.M., et al. The ERdj5-Sel1L complex facilitates cholera toxin retrotranslocation. Mol. Biol. Cell 24 (2013), 785–795.
-
(2013)
Mol. Biol. Cell
, vol.24
, pp. 785-795
-
-
Williams, J.M.1
-
52
-
-
84969749567
-
Direct and essential function for Hrd3 in ER-associated degradation
-
Vashistha, N., et al. Direct and essential function for Hrd3 in ER-associated degradation. Proc. Natl. Acad. Sci. U. S. A. 113 (2016), 5934–5939.
-
(2016)
Proc. Natl. Acad. Sci. U. S. A.
, vol.113
, pp. 5934-5939
-
-
Vashistha, N.1
-
53
-
-
84909962081
-
Quality control of inner nuclear membrane proteins by the Asi complex
-
Foresti, O., et al. Quality control of inner nuclear membrane proteins by the Asi complex. Science 346 (2014), 751–755.
-
(2014)
Science
, vol.346
, pp. 751-755
-
-
Foresti, O.1
-
54
-
-
84922218720
-
Protein quality control at the inner nuclear membrane
-
Khmelinskii, A., et al. Protein quality control at the inner nuclear membrane. Nature 516 (2014), 410–413.
-
(2014)
Nature
, vol.516
, pp. 410-413
-
-
Khmelinskii, A.1
-
55
-
-
84869464499
-
RING-finger type E3 ubiquitin ligase inhibitors as novel candidates for the treatment of rheumatoid arthritis
-
Yagishita, N., et al. RING-finger type E3 ubiquitin ligase inhibitors as novel candidates for the treatment of rheumatoid arthritis. Int. J. Mol. Med. 30 (2012), 1281–1286.
-
(2012)
Int. J. Mol. Med.
, vol.30
, pp. 1281-1286
-
-
Yagishita, N.1
-
56
-
-
0027305620
-
A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus
-
Mori, K., et al. A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus. Cell 74 (1993), 743–756.
-
(1993)
Cell
, vol.74
, pp. 743-756
-
-
Mori, K.1
-
57
-
-
0026710871
-
IRE1 encodes a putative protein kinase containing a membrane-spanning domain and is required for inositol phototrophy in Saccharomyces cerevisiae
-
Nikawa, J., Yamashita, S., IRE1 encodes a putative protein kinase containing a membrane-spanning domain and is required for inositol phototrophy in Saccharomyces cerevisiae. Mol. Microbiol. 6 (1992), 1441–1446.
-
(1992)
Mol. Microbiol.
, vol.6
, pp. 1441-1446
-
-
Nikawa, J.1
Yamashita, S.2
-
58
-
-
0027324844
-
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase
-
Cox, J.S., et al. Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase. Cell 73 (1993), 1197–1206.
-
(1993)
Cell
, vol.73
, pp. 1197-1206
-
-
Cox, J.S.1
-
59
-
-
0032525990
-
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells
-
Tirasophon, W., et al. A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells. Genes Dev. 12 (1998), 1812–1824.
-
(1998)
Genes Dev.
, vol.12
, pp. 1812-1824
-
-
Tirasophon, W.1
-
60
-
-
0032190546
-
Cloning of mammalian Ire1 reveals diversity in the ER stress responses
-
Wang, X.Z., et al. Cloning of mammalian Ire1 reveals diversity in the ER stress responses. EMBO J. 17 (1998), 5708–5717.
-
(1998)
EMBO J.
, vol.17
, pp. 5708-5717
-
-
Wang, X.Z.1
-
61
-
-
0034724520
-
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
-
Travers, K.J., et al. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell 101 (2000), 249–258.
-
(2000)
Cell
, vol.101
, pp. 249-258
-
-
Travers, K.J.1
-
62
-
-
0037320265
-
A time-dependent phase shift in the mammalian unfolded protein response
-
Yoshida, H., et al. A time-dependent phase shift in the mammalian unfolded protein response. Dev. Cell 4 (2003), 265–271.
-
(2003)
Dev. Cell
, vol.4
, pp. 265-271
-
-
Yoshida, H.1
-
63
-
-
36049023152
-
A different pathway in the endoplasmic reticulum stress-induced expression of human HRD1 and SEL1 genes
-
Kaneko, M., et al. A different pathway in the endoplasmic reticulum stress-induced expression of human HRD1 and SEL1 genes. FEBS Lett. 581 (2007), 5355–5360.
-
(2007)
FEBS Lett.
, vol.581
, pp. 5355-5360
-
-
Kaneko, M.1
-
64
-
-
43049096083
-
Synoviolin promotes IRE1 ubiquitination and degradation in synovial fibroblasts from mice with collagen-induced arthritis
-
Gao, B., et al. Synoviolin promotes IRE1 ubiquitination and degradation in synovial fibroblasts from mice with collagen-induced arthritis. EMBO Rep. 9 (2008), 480–485.
-
(2008)
EMBO Rep.
, vol.9
, pp. 480-485
-
-
Gao, B.1
-
65
-
-
63549121490
-
NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer
-
Hayes, J.D., McMahon, M., NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer. Trends Biochem. Sci. 34 (2009), 176–188.
-
(2009)
Trends Biochem. Sci.
, vol.34
, pp. 176-188
-
-
Hayes, J.D.1
McMahon, M.2
-
66
-
-
3543008924
-
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
-
Kobayashi, A., et al. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2. Mol. Cell Biol. 24 (2004), 7130–7139.
-
(2004)
Mol. Cell Biol.
, vol.24
, pp. 7130-7139
-
-
Kobayashi, A.1
-
67
-
-
79952256187
-
SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner
-
Rada, P., et al. SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner. Mol. Cell Biol. 31 (2011), 1121–1133.
-
(2011)
Mol. Cell Biol.
, vol.31
, pp. 1121-1133
-
-
Rada, P.1
-
68
-
-
84978194206
-
Genome-wide association study in mice identifies loci affecting liver-related phenotypes including Sel1l influencing serum bile acids
-
Wu, W., et al. Genome-wide association study in mice identifies loci affecting liver-related phenotypes including Sel1l influencing serum bile acids. Hepatology 63 (2016), 1943–1956.
-
(2016)
Hepatology
, vol.63
, pp. 1943-1956
-
-
Wu, W.1
-
69
-
-
0029163399
-
Genetics of responsiveness to high-fat and high-cholesterol diets in the mouse
-
Paigen, B., Genetics of responsiveness to high-fat and high-cholesterol diets in the mouse. Am. J. Clin. Nutr. 62 (1995), 458S–462S.
-
(1995)
Am. J. Clin. Nutr.
, vol.62
, pp. 458S-462S
-
-
Paigen, B.1
-
70
-
-
0003732734
-
Immunobiology: The Immune System in Health & Disease
-
5th edn Garland Publishing Inc
-
Janeway, C.A. Jr, et al. Immunobiology: The Immune System in Health & Disease. 5th edn, 2001, Garland Publishing Inc, 7:1–7:35.
-
(2001)
, pp. 71-7:35
-
-
Janeway, C.A.1
-
71
-
-
85002713183
-
The Sel1L-Hrd1 endoplasmic reticulum-associated degradation complex manages a key checkpoint in B cell development
-
Ji, Y., et al. The Sel1L-Hrd1 endoplasmic reticulum-associated degradation complex manages a key checkpoint in B cell development. Cell Rep. 16 (2016), 2630–2640.
-
(2016)
Cell Rep.
, vol.16
, pp. 2630-2640
-
-
Ji, Y.1
-
72
-
-
84873342483
-
Regulation of dendritic cell activation by microRNA let-7c and BLIMP1
-
Kim, S.J., et al. Regulation of dendritic cell activation by microRNA let-7c and BLIMP1. J. Clin. Invest. 123 (2013), 823–833.
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 823-833
-
-
Kim, S.J.1
-
73
-
-
77950343252
-
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
-
Hotamisligil, G., Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 140 (2010), 900–917.
-
(2010)
Cell
, vol.140
, pp. 900-917
-
-
Hotamisligil, G.1
-
74
-
-
77955342864
-
A Phos-tag-based method reveals the extent of physiological endoplasmic reticulum stress
-
Yang, L., et al. A Phos-tag-based method reveals the extent of physiological endoplasmic reticulum stress. PLoS One, 5, 2010, e11621.
-
(2010)
PLoS One
, vol.5
, pp. e11621
-
-
Yang, L.1
-
75
-
-
79251504265
-
Detecting and quantitating physiological endoplasmic reticulum stress
-
Qi, L., et al. Detecting and quantitating physiological endoplasmic reticulum stress. Methods Enzymol. 490 (2011), 137–146.
-
(2011)
Methods Enzymol.
, vol.490
, pp. 137-146
-
-
Qi, L.1
-
76
-
-
84938209174
-
Endoplasmic reticulum quality control in cancer: friend or foe
-
Kim, H., et al. Endoplasmic reticulum quality control in cancer: friend or foe. Semin. Cancer Biol. 33 (2015), 25–33.
-
(2015)
Semin. Cancer Biol.
, vol.33
, pp. 25-33
-
-
Kim, H.1
-
77
-
-
77956795163
-
Widespread protein aggregation as an inherent part of aging in C elegans
-
David, D.C., et al. Widespread protein aggregation as an inherent part of aging in C elegans. PLoS Biol., 8, 2010, e1000450.
-
(2010)
PLoS Biol.
, vol.8
, pp. e1000450
-
-
David, D.C.1
-
78
-
-
17144365015
-
Proinsulin disulfide maturation and misfolding in the endoplasmic reticulum
-
Liu, M., et al. Proinsulin disulfide maturation and misfolding in the endoplasmic reticulum. J. Biol. Chem. 280 (2005), 13209–13212.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 13209-13212
-
-
Liu, M.1
-
79
-
-
67749096213
-
Proinsulin and the genetics of diabetes mellitus
-
Weiss, M.A., Proinsulin and the genetics of diabetes mellitus. J. Biol. Chem. 284 (2009), 19159–19163.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 19159-19163
-
-
Weiss, M.A.1
-
80
-
-
84992268836
-
Mutations in the amino-terminal region of proopiomelanocortin (POMC) in patients with early-onset obesity impair POMC sorting to the regulated secretory pathway
-
Creemers, J.W., et al. Mutations in the amino-terminal region of proopiomelanocortin (POMC) in patients with early-onset obesity impair POMC sorting to the regulated secretory pathway. J. Clin. Endocrinol. Metab. 93 (2008), 4494–4499.
-
(2008)
J. Clin. Endocrinol. Metab.
, vol.93
, pp. 4494-4499
-
-
Creemers, J.W.1
-
81
-
-
70450230337
-
Dominant pro-vasopressin mutants that cause diabetes insipidus form disulfide-linked fibrillar aggregates in the endoplasmic reticulum
-
Birk, J., et al. Dominant pro-vasopressin mutants that cause diabetes insipidus form disulfide-linked fibrillar aggregates in the endoplasmic reticulum. J. Cell. Sci. 122 (2009), 3994–4002.
-
(2009)
J. Cell. Sci.
, vol.122
, pp. 3994-4002
-
-
Birk, J.1
-
82
-
-
2442475348
-
Degradation of wild-type vasopressin precursor and pathogenic mutants by the proteasome
-
Friberg, M.A., et al. Degradation of wild-type vasopressin precursor and pathogenic mutants by the proteasome. J. Biol. Chem. 279 (2004), 19441–19447.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 19441-19447
-
-
Friberg, M.A.1
-
83
-
-
84957801406
-
Thyroglobulin from molecular and cellular biology to clinical endocrinology
-
Di Jeso, B., Arvan, P., Thyroglobulin from molecular and cellular biology to clinical endocrinology. Endocr. Rev. 37 (2016), 2–36.
-
(2016)
Endocr. Rev.
, vol.37
, pp. 2-36
-
-
Di Jeso, B.1
Arvan, P.2
-
84
-
-
84962140678
-
Disulfide mispairing during proinsulin folding in the endoplasmic reticulum
-
Haataja, L., et al. Disulfide mispairing during proinsulin folding in the endoplasmic reticulum. Diabetes 65 (2016), 1050–1060.
-
(2016)
Diabetes
, vol.65
, pp. 1050-1060
-
-
Haataja, L.1
-
85
-
-
84943140507
-
PDI reductase acts on Akita mutant proinsulin to initiate retrotranslocation along the Hrd1/Sel1L-p97 axis
-
He, K., et al. PDI reductase acts on Akita mutant proinsulin to initiate retrotranslocation along the Hrd1/Sel1L-p97 axis. Mol. Biol. Cell 26 (2015), 3413–3423.
-
(2015)
Mol. Biol. Cell
, vol.26
, pp. 3413-3423
-
-
He, K.1
|