Human HRD1 Is an E3 Ubiquitin Ligase Involved in Degradation of Proteins from the Endoplasmic Reticulum

Journal of Biological Chemistry

Volumn 279, Issue 5, 2004, Pages 3525-3534

  Kikkert, Marjolein ^a   Doolman, Ram ^b   Dai, Min ^c   Avner, Rachel ^b   Hassink, Gerco ^a   Van Voorden, Sjaak ^a   Thanedar, Swapna ^c   Roitelman, Joseph ^b   Chau, Vincent ^c   Wiertz, Emmanuel ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b SHEBA MEDICAL CENTER   (Israel)

^c PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COENZYMES; DEGRADATION; METABOLISM; SUBSTRATES; YEAST;

OLIGOMERIZATION;

BIOCHEMISTRY;

CD3 ANTIGEN; HRD1 PROTEIN, HUMAN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LYSINE; POLYUBIQUITIN; PROTEIN; PROTEIN HRD1; PROTEINASE K; STEROL; TRANSMEMBRANE CONDUCTANCE REGULATOR; UBE2G2 PROTEIN, HUMAN; UBIQUITIN; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL; ANIMAL CELL; ARTICLE; BIOSYNTHESIS; CELL STRAIN 3T3; CHEMISTRY; ENDOPLASMIC RETICULUM; ENZYME METABOLISM; ENZYME SUBSTRATE; ENZYMOLOGY; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; GENETICS; GLYCOSYLATION; HELA CELL; HUMAN; METABOLISM; MOLECULAR GENETICS; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OLIGOMERIZATION; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN SYNTHESIS; PROTEIN TERTIARY STRUCTURE; RNA TRANSLATION; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; T LYMPHOCYTE RECEPTOR GENE; TIME; UBIQUITINATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD3; ENDOPEPTIDASE K; ENDOPLASMIC RETICULUM; GENES, T-CELL RECEPTOR ALPHA; GLYCOSYLATION; HELA CELLS; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; LYSINE; MICE; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; NIH 3T3 CELLS; PROTEIN BIOSYNTHESIS; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, AMINO ACID; STEROLS; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS; TRANSFECTION; UBIQUITIN; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITIN-PROTEIN LIGASES;

ANIMALIA; SACCHAROMYCES CEREVISIAE;

EID: 9144239817     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M307453200     Document Type: Article

References (55)

1. Weissman, A. M. (2001) Nat. Rev. Mol. Cell. Biol. 2, 169-178
2. Ward, C. L., Omura, S., and Kopito, R. R. (1995) Cell 83, 121-127
3. Yang, M., Omura, S., Bonifacino, J. S., and Weissman, A. M. (1998) J. Exp. Med. 187, 835-846
4. Gardner, R. G., Shearer, A. G., and Hampton, R. Y. (2001) Mol. Cell. Biol. 21, 4276-4291
5. Fisher, E. A., Zhou, M., Mitchell, D. M., Wu, X., Omura, S., Wang, H., Goldberg, A. L., and Ginsberg, H. N. (1997) J. Biol. Chem. 272, 20427-20434
6. Wiertz, E. J., Tortorella, D., Bogyo, M., Yu, J., Mothes, W., Jones, T. R., Rapoport, T. A., and Ploegh, H. L. (1996) Nature 384, 432-438
7. Zhou, M., and Schekman, R. (1999) Mol. Cell 4, 925-934
8. Pilon, M., Schekman, R., and Romisch, K. (1997) EMBO J. 16, 4540-4548
9. Jarosch, E., Taxis, C., Volkwein, C., Bordallo, J., Finley, D., Wolf, D. H., and Sommer, T. (2002) Nat. Cell Biol. 4, 134-139
10. Rabinovich, E., Kerem, A., Frohlich, K. U., Diamant, N., and Bar-Nun, S. (2002) Mol. Cell. Biol. 22, 626-634
11. Ye, Y., Meyer, H. H., and Rapoport, T. A. (2001) Nature 414, 652-656
12. Sifers, R. N., Brashears-Macatee, S., Kidd, V. J., Muensch, H., and Woo, S. L. (1988) J. Biol. Chem. 263, 7330-7335
13. Shamu, C. E., Flierman, D., Ploegh, H. L., Rapoport, T. A., and Chau, V. (2001) Mol. Biol. Cell 12, 2546-2555
14. Kikkert, M., Hassink, G., Barel, M., Hirsch, C., van der Wal, F. J., and Wiertz, E. (2001) Biochem. J. 358, 369-377
15. de Virgilio, M., Kitzmuller, C., Schwaiger, E., Klein, M., Kreibich, G., and Ivessa, N. E. (1999) Mol. Biol. Cell 10, 4059-4073
16. Tsai, B., Ye, Y., and Rapoport, T. A. (2002) Nat. Rev. Mol. Cell. Biol. 3, 246-255
17. Pickart, C. M. (2001) Annu. Rev. Biochem. 70, 503-533
18. Joazeiro, C. A., and Weissman, A. M. (2000) Cell 102, 549-552
19. Jackson, P. K., Eldridge, A. G., Freed, E., Furstenthal, L., Hsu, J. Y., Kaiser, B. K., and Reimann, J. D. (2000) Trends Cell Biol. 10, 429-439
20. Freemont, P. S. (2000) Curr. Biol. 10, R84-R87
21. Coscoy, L., and Ganem, D. (2003) Trends Cell Biol. 13, 7-12
22. Hampton, R. Y., Gardner, R. G., and Rine, J. (1996) Mol. Biol. Cell 7, 2029-2044
23. Bordallo, J., Plemper, R. K., Finger, A., and Wolf, D. H. (1998) Mol. Biol. Cell 9, 209-222
24. Goldstein, J. L., and Brown, M. S. (1990) Nature 343, 425-430
25. Roitelman, J., and Simoni, R. D. (1992) J. Biol. Chem. 267, 25264-25273
26. Gardner, R. G., Shan, H., Matsuda, S. P., and Hampton, R. Y. (2001) J. Biol. Chem. 276, 8681-8694
27. Gardner, R. G., and Hampton, R. Y. (1999) J. Biol. Chem. 274, 31671-31678
28. Ravid, T., Doolman, R., Avner, R., Harats, D., and Roitelman, J. (2000) J. Biol. Chem. 275, 35840-35847
29. Bays, N. W., Gardner, R. G., Seelig, L. P., Joazeiro, C. A., and Hampton, R. Y. (2001) Nat. Cell Biol. 3, 24-29
30. Gardner, R. G., Swarbrick, G. M., Bays, N. W., Cronin, S. R., Wilhovsky, S., Seelig, L., Kim, C., and Hampton, R. Y. (2000) J. Cell Biol. 151, 69-82
31. Friedlander, R., Jarosch, E., Urban, J., Volkwein, C., and Sommer, T. (2000) Nat. Cell Biol. 2, 379-384
32. Swanson, R., Locher, M., and Hochstrasser, M. (2001) Genes Dev. 15, 2660-2674
33. Haynes, C. M., Caldwell, S., and Cooper, A. A. (2002) J. Cell Biol. 158, 91-101
34. Fang, S., Ferrone, M., Yang, C., Jensen, J. P., Tiwari, S., and Weissman, A. M. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 14422-14427
35. Liang, J. S., Kim, T., Fang, S., Yamaguchi, J., Weissman, A. M., Fisher, E. A., and Ginsberg, H. N. (2003) J. Biol. Chem. 278, 23984-23988
36. Meacham, G. C., Patterson, C., Zhang, W., Younger, J. M., and Cyr, D. M. (2001) Nat. Cell Biol. 3, 100-105
37. Connell, P., Ballinger, C. A., Jiang, J., Wu, Y., Thompson, L. J., Hohfeld, J., and Patterson, C. (2001) Nat. Cell Biol. 3, 93-96
38. Yoshida, Y., Chiba, T., Tokunaga, F., Kawasaki, H., Iwai, K., Suzuki, T., Ito, Y., Matsuoka, K., Yoshida, M., Tanaka, K., and Tai, T. (2002) Nature 418, 438-442
39. Goldstein, J. L., Basu, S. K., and Brown, M. S. (1983) Methods Enzymol. 98, 241-260
40. Kikuno, R., Nagase, T., Waki, M., and Ohara, O. (2002) Nucleic Acids Res. 30, 166-168
41. Roitelman, J., Olender, E. H., Bar-Nun, S., Dunn, W. A., Jr., and Simoni, R. D. (1992) J. Cell Biol. 117, 959-973
42. Lew, A. M., Maloy, W. L., Koning, F., Valas, R., and Coligan, J. E. (1987) J. Immunol. 138, 807-814
43. Read, M. A., Brownell, J. E., Gladysheva, T. B., Hottelet, M., Parent, L. A., Coggins, M. B., Pierce, J. W., Podust, V. N., Luo, R. S., Chau, V., and Palombella, V. J. (2000) Mol. Cell. Biol. 20, 2326-2333
44. Haas, A. L., Reback, P. B., and Chau, V. (1991) J. Biol. Chem. 266, 5104-5112
45. Cook, W. J., Martin, P. D., Edwards, B. F., Yamazaki, R. K., and Chau, V. (1997) Biochemistry (Mosc.) 36, 1621-1627
46. Kaneko, M., Ishiguro, M., Niinuma, Y., Uesugi, M., and Nomura, Y. (2002) FEBS Lett. 532, 147-152
47. Kyte, J., and Doalittle, R. F. (1982) J. Mol. Biol. 157, 105-132
48. Deak, P. M., and Wolf, D. H. (2001) J. Biol. Chem. 276, 10663-10669
49. Finley, D., Sadis, S., Monia, B. P., Boucher, P., Ecker, D. J., Crooke, S. T., and Chau, V. (1994) Mol. Cell. Biol. 14, 5501-5509
50. Chau, V., Tobias, J. W., Bachmair, A., Marriott, D., Ecker, D. J., Gonda, D. K., and Varshavsky, A. (1989) Science 243, 1576-1583
51. Nadav, E., Shmueli, A., Barr, H., Gonen, H., Ciechanover, A., and Reiss, Y. (2003) Biochem. Biophys. Res. Commun. 303, 91-97
52. Gregori, L., Poosch, M. S., Cousins, G., and Chau, V. (1990) J. Biol. Chem. 265, 8354-8357
53. Sever, N., Yang, T., Brown, M. S., Goldstein, J. L., and DeBose-Boyd, R. A. (2003) Mol. Cell 11, 25-33
54. Xu, L., and Simoni, R. D. (2003) Arch. Biochem. Biophys. 414, 232-243
55. Ponting, C. P. (2000) Biochem. J. 351, 527-535