메뉴 건너뛰기




Volumn 131, Issue , 2018, Pages 2-11

CRISPR-Cas9 based plant genome editing: Significance, opportunities and recent advances

Author keywords

Cisgenics; CRISPR Cas9; Gene editing; Marker free transgenics; Mutations

Indexed keywords

CRISPR CAS SYSTEM; CROP; GENE EDITING; GENETICS; PLANT; PLANT GENOME; PROCEDURES; TRANSGENIC PLANT;

EID: 85032907233     PISSN: 09819428     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.plaphy.2017.10.024     Document Type: Review
Times cited : (46)

References (112)
  • 1
    • 84950276046 scopus 로고    scopus 로고
    • Europe's genetically edited plants stuck in legal limbo
    • Abbott, A., Europe's genetically edited plants stuck in legal limbo. Nature 528 (2015), 319–320.
    • (2015) Nature , vol.528 , pp. 319-320
    • Abbott, A.1
  • 3
    • 84989951388 scopus 로고    scopus 로고
    • Efficient targeted multiallelic mutagenesis in tetraploid potato (Solanum tuberosum) by transient CRISPR-Cas9 expression in protoplasts
    • Andersson, M., Turesson, H., Nicolia, A., Fält, A.S., Samuelsson, M., et al. Efficient targeted multiallelic mutagenesis in tetraploid potato (Solanum tuberosum) by transient CRISPR-Cas9 expression in protoplasts. Plant Cell Rep. 36 (2017), 117–128.
    • (2017) Plant Cell Rep. , vol.36 , pp. 117-128
    • Andersson, M.1    Turesson, H.2    Nicolia, A.3    Fält, A.S.4    Samuelsson, M.5
  • 4
    • 85023209110 scopus 로고    scopus 로고
    • Simultaneous targeting of multiple gene homeologues to alter seed oil production in Camelina sativa
    • Aznar-Moreno, J.A., Durrett, T.P., Simultaneous targeting of multiple gene homeologues to alter seed oil production in Camelina sativa. Plant Cell Physiol., 2017, 10.1093/pcp/pcx058.
    • (2017) Plant Cell Physiol.
    • Aznar-Moreno, J.A.1    Durrett, T.P.2
  • 6
    • 84885353478 scopus 로고    scopus 로고
    • Plant genome editing made easy: targeted mutagenesis in model and crop plants using the CRISPR/Cas system
    • Belhaj, K., Chaparro-Garcia, A., Kamoun, S., Nekrasov, V., Plant genome editing made easy: targeted mutagenesis in model and crop plants using the CRISPR/Cas system. Plant Methods, 9, 2013, 39.
    • (2013) Plant Methods , vol.9 , pp. 39
    • Belhaj, K.1    Chaparro-Garcia, A.2    Kamoun, S.3    Nekrasov, V.4
  • 7
    • 80755187812 scopus 로고    scopus 로고
    • CRISPR-Cas systems in bacteria and archaea: versatile small RNAs for adaptive defense and regulation
    • Bhaya, D., Davison, M., Barrangou, R., CRISPR-Cas systems in bacteria and archaea: versatile small RNAs for adaptive defense and regulation. Annu. Rev. Genet. 45 (2011), 273–297.
    • (2011) Annu. Rev. Genet. , vol.45 , pp. 273-297
    • Bhaya, D.1    Davison, M.2    Barrangou, R.3
  • 8
    • 77956126894 scopus 로고    scopus 로고
    • Xanthomonas AvrBs3 family-type III effectors: discovery and function
    • Boch, J., Bonas, U., Xanthomonas AvrBs3 family-type III effectors: discovery and function. Annu. Rev. Phytopathol. 48 (2010), 419–436.
    • (2010) Annu. Rev. Phytopathol. , vol.48 , pp. 419-436
    • Boch, J.1    Bonas, U.2
  • 9
    • 84920262090 scopus 로고    scopus 로고
    • The CRISPR system for plant genome editing and beyond
    • Bortesi, L., Fischer, R., The CRISPR system for plant genome editing and beyond. Biotechnol. Adv. 33 (2015), 41–52.
    • (2015) Biotechnol. Adv. , vol.33 , pp. 41-52
    • Bortesi, L.1    Fischer, R.2
  • 10
    • 84908584019 scopus 로고    scopus 로고
    • Efficient gene editing in tomato in the first generation using the clustered regularly interspaced short palindromic repeats/CRISPR-associated9 system
    • Brooks, C., Nekrasov, V., Lippman, Z.B., Van Eck, J., Efficient gene editing in tomato in the first generation using the clustered regularly interspaced short palindromic repeats/CRISPR-associated9 system. Plant Physiol. 166 (2014), 1292–1297.
    • (2014) Plant Physiol. , vol.166 , pp. 1292-1297
    • Brooks, C.1    Nekrasov, V.2    Lippman, Z.B.3    Van Eck, J.4
  • 12
    • 85027950047 scopus 로고    scopus 로고
    • Development of broad virus resistance in non-transgenic cucumber using CRISPR/Cas9 technology
    • Chandrasekaran, J., Brumin, M., Wolf, D., Leibman, D., Klap, C., et al. Development of broad virus resistance in non-transgenic cucumber using CRISPR/Cas9 technology. Mol. Plant Pathol. 17 (2016), 1140–1153.
    • (2016) Mol. Plant Pathol. , vol.17 , pp. 1140-1153
    • Chandrasekaran, J.1    Brumin, M.2    Wolf, D.3    Leibman, D.4    Klap, C.5
  • 13
    • 84997712029 scopus 로고    scopus 로고
    • An Agrobacterium-delivered CRISPR/Cas9 system for high-frequency targeted mutagenesis in maize
    • Char, S.N., Neelakandan, A.K., Nahampun, H., Frame, B., Main, M., et al. An Agrobacterium-delivered CRISPR/Cas9 system for high-frequency targeted mutagenesis in maize. Plant Biotechnol. J. 15 (2017), 257–268.
    • (2017) Plant Biotechnol. J. , vol.15 , pp. 257-268
    • Char, S.N.1    Neelakandan, A.K.2    Nahampun, H.3    Frame, B.4    Main, M.5
  • 14
    • 84894063115 scopus 로고    scopus 로고
    • Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system
    • Chen, B., Gilbert, L.A., Cimini, B.A., Schnitzbauer, J., Zhang, W., Li, et al. Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system. Cell 155 (2013), 1479–1491.
    • (2013) Cell , vol.155 , pp. 1479-1491
    • Chen, B.1    Gilbert, L.A.2    Cimini, B.A.3    Schnitzbauer, J.4    Zhang, W.5    Li6
  • 15
    • 84966359029 scopus 로고    scopus 로고
    • Expanding the CRISPR imaging toolset with Staphylococcus aureus Cas9 for simultaneous imaging of multiple genomic loci
    • Chen, B., Hu, J., Almeida, R., Liu, H., Balakrishnan, S., et al. Expanding the CRISPR imaging toolset with Staphylococcus aureus Cas9 for simultaneous imaging of multiple genomic loci. Nucleic Acids Res., 44, 2016, e75.
    • (2016) Nucleic Acids Res. , vol.44 , pp. e75
    • Chen, B.1    Hu, J.2    Almeida, R.3    Liu, H.4    Balakrishnan, S.5
  • 16
    • 84875298381 scopus 로고    scopus 로고
    • A large-scale in vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context dependent assembly
    • Chen, S., Oikonomou, G., Chiu, C.N., Niles, B.J., Liu, J., et al. A large-scale in vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context dependent assembly. Nucleic Acids Res. 41 (2013), 2769–2778.
    • (2013) Nucleic Acids Res. , vol.41 , pp. 2769-2778
    • Chen, S.1    Oikonomou, G.2    Chiu, C.N.3    Niles, B.J.4    Liu, J.5
  • 17
    • 85015626714 scopus 로고    scopus 로고
    • CRISPR/Cas9-mediated base-editing system efficiently generates gain-of-function mutations in Arabidopsis
    • Chen, Y., Wang, Z., Ni, H., Xu, Y., Chen, Q., et al. CRISPR/Cas9-mediated base-editing system efficiently generates gain-of-function mutations in Arabidopsis. Sci. China Life Sci., 2017, 10.1007/s11427-017-9021-5.
    • (2017) Sci. China Life Sci.
    • Chen, Y.1    Wang, Z.2    Ni, H.3    Xu, Y.4    Chen, Q.5
  • 18
    • 84885180675 scopus 로고    scopus 로고
    • Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system
    • Cheng, A.W., Wang, H., Yang, H., Shi, L., Katz, Y., et al. Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system. Cell Res. 23 (2013), 1163–1171.
    • (2013) Cell Res. , vol.23 , pp. 1163-1171
    • Cheng, A.W.1    Wang, H.2    Yang, H.3    Shi, L.4    Katz, Y.5
  • 19
    • 84898961107 scopus 로고    scopus 로고
    • Opportunities in plant synthetic biology
    • Cook, C., Martin, L., Bastow, R., Opportunities in plant synthetic biology. J. Exp. Bot. 65 (2014), 1921–1926.
    • (2014) J. Exp. Bot. , vol.65 , pp. 1921-1926
    • Cook, C.1    Martin, L.2    Bastow, R.3
  • 20
    • 84871794394 scopus 로고    scopus 로고
    • Genome engineering of crops with designer nucleases
    • Curtin, S.J., Voytas, D.F., Stupar, R.M., Genome engineering of crops with designer nucleases. Plant Genome 5 (2012), 42–50.
    • (2012) Plant Genome , vol.5 , pp. 42-50
    • Curtin, S.J.1    Voytas, D.F.2    Stupar, R.M.3
  • 21
    • 84926612621 scopus 로고    scopus 로고
    • The new frontier of genome engineering with CRISPR-Cas9
    • Doudna, J.A., Charpentier, E., The new frontier of genome engineering with CRISPR-Cas9. Science 346 (2014), 1077–1093.
    • (2014) Science , vol.346 , pp. 1077-1093
    • Doudna, J.A.1    Charpentier, E.2
  • 22
    • 85023642711 scopus 로고    scopus 로고
    • Live cell CRISPR-imaging in plants reveals dynamic telomere movements
    • Dreissig, S., Schiml, S., Schindele, P., Weiss, O., Rutten, T., et al. Live cell CRISPR-imaging in plants reveals dynamic telomere movements. Plant J. 91 (2017), 565–573.
    • (2017) Plant J. , vol.91 , pp. 565-573
    • Dreissig, S.1    Schiml, S.2    Schindele, P.3    Weiss, O.4    Rutten, T.5
  • 23
    • 84971006580 scopus 로고    scopus 로고
    • High efficiency of targeted mutagenesis in Arabidopsis via meiotic promoter-driven expression of Cas9 endonuclease
    • Eid, A., Ali, Z., Mahfouz, M.M., High efficiency of targeted mutagenesis in Arabidopsis via meiotic promoter-driven expression of Cas9 endonuclease. Plant Cell Rep. 35 (2016), 1555–1558.
    • (2016) Plant Cell Rep. , vol.35 , pp. 1555-1558
    • Eid, A.1    Ali, Z.2    Mahfouz, M.M.3
  • 24
    • 84937702694 scopus 로고    scopus 로고
    • Efficient CRISPR/Cas9-mediated targeted mutagenesis in Populus in the first generation
    • Fan, D., Liu, T., Li, C., Jiao, B., Li, S., et al. Efficient CRISPR/Cas9-mediated targeted mutagenesis in Populus in the first generation. Sci. Rep., 5, 2015, 12217.
    • (2015) Sci. Rep. , vol.5 , pp. 12217
    • Fan, D.1    Liu, T.2    Li, C.3    Jiao, B.4    Li, S.5
  • 25
    • 84904068340 scopus 로고    scopus 로고
    • Both CRISPR/Cas-based nucleases and nickases can be used efficiently for genome engineering in Arabidopsis thaliana
    • Fauser, F., Schiml, S., Puchta, H., Both CRISPR/Cas-based nucleases and nickases can be used efficiently for genome engineering in Arabidopsis thaliana. Plant J. 79 (2014), 348–359.
    • (2014) Plant J. , vol.79 , pp. 348-359
    • Fauser, F.1    Schiml, S.2    Puchta, H.3
  • 26
    • 84957839838 scopus 로고    scopus 로고
    • Efficient targeted genome modification in maize using CRISPR/Cas9 system
    • Feng, C., Yuan, J., Wang, R., Liu, Y., Birchler, J.A., et al. Efficient targeted genome modification in maize using CRISPR/Cas9 system. J. Genet. Genomics 43 (2016), 37–43.
    • (2016) J. Genet. Genomics , vol.43 , pp. 37-43
    • Feng, C.1    Yuan, J.2    Wang, R.3    Liu, Y.4    Birchler, J.A.5
  • 27
    • 84896924524 scopus 로고    scopus 로고
    • Multigeneration analysis reveals the inheritance, specificity, and patterns of CRISPR/Cas-induced gene modifications in Arabidopsis
    • Feng, Z., Mao, Y., Xu, N., Zhang, B., Wei, P., et al. Multigeneration analysis reveals the inheritance, specificity, and patterns of CRISPR/Cas-induced gene modifications in Arabidopsis. Proc. Natl. Acad. Sci. U. S. A. 111 (2014), 4632–4637.
    • (2014) Proc. Natl. Acad. Sci. U. S. A. , vol.111 , pp. 4632-4637
    • Feng, Z.1    Mao, Y.2    Xu, N.3    Zhang, B.4    Wei, P.5
  • 28
    • 84885181396 scopus 로고    scopus 로고
    • Efficient genome editing in plants using a CRISPR/Cas system
    • Feng, Z., Zhang, B., Ding, W., Liu, X., Yang, D.L., et al. Efficient genome editing in plants using a CRISPR/Cas system. Cell Res. 23 (2013), 1229–1232.
    • (2013) Cell Res. , vol.23 , pp. 1229-1232
    • Feng, Z.1    Zhang, B.2    Ding, W.3    Liu, X.4    Yang, D.L.5
  • 29
    • 84879264708 scopus 로고    scopus 로고
    • ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
    • Gaj, T., Gersbach, C.A., Barbas, C.F., ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. Trends Biotechnol. 31 (2013), 397–405.
    • (2013) Trends Biotechnol. , vol.31 , pp. 397-405
    • Gaj, T.1    Gersbach, C.A.2    Barbas, C.F.3
  • 30
    • 84977578000 scopus 로고    scopus 로고
    • An effective strategy for reliably isolating heritable and Cas9-free Arabidopsis mutants generated by CRISPR/Cas9-mediated genome editing
    • Gao, X., Chen, J., Dai, X., Zhang, D., Zhao, Y., An effective strategy for reliably isolating heritable and Cas9-free Arabidopsis mutants generated by CRISPR/Cas9-mediated genome editing. Plant Physiol. 171 (2016), 1794–1800.
    • (2016) Plant Physiol. , vol.171 , pp. 1794-1800
    • Gao, X.1    Chen, J.2    Dai, X.3    Zhang, D.4    Zhao, Y.5
  • 31
    • 84923164523 scopus 로고    scopus 로고
    • Auxin binding protein 1 (ABP1) is not required for either auxin signaling or Arabidopsis development
    • Gao, Y., Zhang, Y., Zhang, D., Dai, X., Estelle, M., Zhao, Y., Auxin binding protein 1 (ABP1) is not required for either auxin signaling or Arabidopsis development. Proc. Natl. Acad. Sci. U. S. A. 112 (2015), 2275–2280.
    • (2015) Proc. Natl. Acad. Sci. U. S. A. , vol.112 , pp. 2275-2280
    • Gao, Y.1    Zhang, Y.2    Zhang, D.3    Dai, X.4    Estelle, M.5    Zhao, Y.6
  • 32
    • 78149261827 scopus 로고    scopus 로고
    • The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA
    • Garneau, J.E., Dupuis, M.E., Villion, M., Romero, D.A., Barrangou, R., et al. The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA. Nature 468 (2010), 67–71.
    • (2010) Nature , vol.468 , pp. 67-71
    • Garneau, J.E.1    Dupuis, M.E.2    Villion, M.3    Romero, D.A.4    Barrangou, R.5
  • 33
    • 84908352138 scopus 로고    scopus 로고
    • Genome-Scale CRISPR-mediated control of gene repression and activation
    • Gilbert, L.A., Horlbeck, M.A., Adamson, B., Villalta, J.E., Chen, Y., et al. Genome-Scale CRISPR-mediated control of gene repression and activation. Cell 159 (2014), 647–661.
    • (2014) Cell , vol.159 , pp. 647-661
    • Gilbert, L.A.1    Horlbeck, M.A.2    Adamson, B.3    Villalta, J.E.4    Chen, Y.5
  • 34
    • 32644451363 scopus 로고    scopus 로고
    • The impact of genetically modified crops on soil microbial communities
    • Giovannetti, M., Sbrana, C., Turrini, A., The impact of genetically modified crops on soil microbial communities. Riv. Biol. Biol. Forum 98 (2005), 393–417.
    • (2005) Riv. Biol. Biol. Forum , vol.98 , pp. 393-417
    • Giovannetti, M.1    Sbrana, C.2    Turrini, A.3
  • 35
    • 84898998655 scopus 로고    scopus 로고
    • Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors
    • Hu, J., Lei, Y., Wong, W.K., Liu, S., Lee, K.C., et al. Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors. Nucleic Acids Res. 42 (2014), 4375–4390.
    • (2014) Nucleic Acids Res. , vol.42 , pp. 4375-4390
    • Hu, J.1    Lei, Y.2    Wong, W.K.3    Liu, S.4    Lee, K.C.5
  • 36
    • 84920435758 scopus 로고    scopus 로고
    • Site-directed mutagenesis in Arabidopsis thaliana using dividing tissue-targeted RGEN of the CRISPR/Cas system to generate heritable null alleles
    • Hyun, Y., Kim, J., Cho, S.W., Choi, Y., Kim, J.S., Coupland, G., Site-directed mutagenesis in Arabidopsis thaliana using dividing tissue-targeted RGEN of the CRISPR/Cas system to generate heritable null alleles. Planta 241 (2015), 271–284.
    • (2015) Planta , vol.241 , pp. 271-284
    • Hyun, Y.1    Kim, J.2    Cho, S.W.3    Choi, Y.4    Kim, J.S.5    Coupland, G.6
  • 37
    • 0023600057 scopus 로고
    • Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product
    • Ishino, Y., Shinagawa, H., Makino, K., Amemura, M., Nakata, A., Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product. J. Bacteriol. 169 (1987), 5429–5433.
    • (1987) J. Bacteriol. , vol.169 , pp. 5429-5433
    • Ishino, Y.1    Shinagawa, H.2    Makino, K.3    Amemura, M.4    Nakata, A.5
  • 38
    • 85018757081 scopus 로고    scopus 로고
    • Significant enhancement of fatty acid composition in seeds of the allohexaploid, Camelina sativa, using CRISPR/Cas9 gene editing
    • Jiang, W.Z., Henry, I.M., Lynagh, P.G., Comai, L., Cahoon, E.B., Significant enhancement of fatty acid composition in seeds of the allohexaploid, Camelina sativa, using CRISPR/Cas9 gene editing. Plant Biotechnol. J. 15 (2017), 648–657.
    • (2017) Plant Biotechnol. J. , vol.15 , pp. 648-657
    • Jiang, W.Z.1    Henry, I.M.2    Lynagh, P.G.3    Comai, L.4    Cahoon, E.B.5
  • 39
    • 84871519181 scopus 로고    scopus 로고
    • TALENs: a widely applicable technology for targeted genome editing
    • Joung, J.K., Sander, J.D., TALENs: a widely applicable technology for targeted genome editing. Nat. Rev. Mol. Cell Biol. 14 (2013), 49–55.
    • (2013) Nat. Rev. Mol. Cell Biol. , vol.14 , pp. 49-55
    • Joung, J.K.1    Sander, J.D.2
  • 40
    • 84892897176 scopus 로고    scopus 로고
    • Genotyping with CRISPR-Cas-derived RNA-guided endonucleases
    • Kim, J.M., Kim, D., Kim, S., Kim, J.S., Genotyping with CRISPR-Cas-derived RNA-guided endonucleases. Nat. Commun., 5, 2014, 3157.
    • (2014) Nat. Commun. , vol.5 , pp. 3157
    • Kim, J.M.1    Kim, D.2    Kim, S.3    Kim, J.S.4
  • 41
    • 0030032063 scopus 로고    scopus 로고
    • Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain
    • Kim, Y.G., Cha, J., Chandrasegaran, S., Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain. Proc. Natl. Acad. Sci. U. S. A. 93 (1996), 1156–1160.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 1156-1160
    • Kim, Y.G.1    Cha, J.2    Chandrasegaran, S.3
  • 42
    • 0031960121 scopus 로고    scopus 로고
    • Chimeric restriction enzyme: Gal4 fusion to FokI cleavage domain
    • Kim, Y.G., Smith, J., Durgesha, M., Chandrasegaran, S., Chimeric restriction enzyme: Gal4 fusion to FokI cleavage domain. Biol. Chem. 379 (1998), 489–495.
    • (1998) Biol. Chem. , vol.379 , pp. 489-495
    • Kim, Y.G.1    Smith, J.2    Durgesha, M.3    Chandrasegaran, S.4
  • 43
    • 85014623651 scopus 로고    scopus 로고
    • Targeted mutagenesis in the medicinal plant Salvia miltiorrhiza
    • Li, B., Cui, G., Shen, G., Zhan, Z., Huang, L., et al. Targeted mutagenesis in the medicinal plant Salvia miltiorrhiza. Sci. Rep., 7, 2017, 43320.
    • (2017) Sci. Rep. , vol.7 , pp. 43320
    • Li, B.1    Cui, G.2    Shen, G.3    Zhan, Z.4    Huang, L.5
  • 44
    • 84860736700 scopus 로고    scopus 로고
    • High-efficiency TALEN-based gene editing produces disease-resistant rice
    • Li, T., Liu, B., Spalding, M.H., Weeks, D.P., Yang, B., High-efficiency TALEN-based gene editing produces disease-resistant rice. Nat. Biotechnol. 30 (2012), 390–392.
    • (2012) Nat. Biotechnol. , vol.30 , pp. 390-392
    • Li, T.1    Liu, B.2    Spalding, M.H.3    Weeks, D.P.4    Yang, B.5
  • 45
    • 84942908491 scopus 로고    scopus 로고
    • Cas9-guide RNA directed genome editing in soybean
    • Li, Z., Liu, Z., Xing, A., Moon, B.P., Koellhoffer, J.P., et al. Cas9-guide RNA directed genome editing in soybean. Plant Physiol. 169 (2015), 960–970.
    • (2015) Plant Physiol. , vol.169 , pp. 960-970
    • Li, Z.1    Liu, Z.2    Xing, A.3    Moon, B.P.4    Koellhoffer, J.P.5
  • 46
    • 85010058709 scopus 로고    scopus 로고
    • Efficient DNA-free genome editing of bread wheat using CRISPR/Cas9 ribonucleoprotein complexes
    • Liang, Z., Chen, K., Li, T., Zhang, Y., Wang, Y., et al. Efficient DNA-free genome editing of bread wheat using CRISPR/Cas9 ribonucleoprotein complexes. Nat. Commun., 8, 2017, 14261.
    • (2017) Nat. Commun. , vol.8 , pp. 14261
    • Liang, Z.1    Chen, K.2    Li, T.3    Zhang, Y.4    Wang, Y.5
  • 47
    • 84894321885 scopus 로고    scopus 로고
    • Targeted mutagenesis in Zea mays using TALENs and the CRISPR/Cas system
    • Liang, Z., Zhang, K., Chen, K., Gao, C., Targeted mutagenesis in Zea mays using TALENs and the CRISPR/Cas system. J. Genet. Genomics 41 (2014), 63–68.
    • (2014) J. Genet. Genomics , vol.41 , pp. 63-68
    • Liang, Z.1    Zhang, K.2    Chen, K.3    Gao, C.4
  • 48
    • 85017389847 scopus 로고    scopus 로고
    • GW5 acts in the brassinosteroid signalling pathway to regulate grain width and weight in rice
    • Liu, J., Chen, J., Zheng, X., Wu, F., Lin, Q., et al. GW5 acts in the brassinosteroid signalling pathway to regulate grain width and weight in rice. Nat. Plants, 3, 2017, 17043.
    • (2017) Nat. Plants , vol.3 , pp. 17043
    • Liu, J.1    Chen, J.2    Zheng, X.3    Wu, F.4    Lin, Q.5
  • 49
    • 84973410860 scopus 로고    scopus 로고
    • CRISPR/Cas9-based genome editing systems and analysis of targeted genome mutations in plants
    • Ma, X., Liu, Y.G., CRISPR/Cas9-based genome editing systems and analysis of targeted genome mutations in plants. Hered. (Beijing) 38 (2016), 118–125.
    • (2016) Hered. (Beijing) , vol.38 , pp. 118-125
    • Ma, X.1    Liu, Y.G.2
  • 50
    • 84938748218 scopus 로고    scopus 로고
    • A robust CRISPR/Cas9 system for convenient, high-efficiency multiplex genome editing in monocot and dicot plants
    • Ma, X., Zhang, Q., Zhu, Q., Liu, W., Chen, Y., et al. A robust CRISPR/Cas9 system for convenient, high-efficiency multiplex genome editing in monocot and dicot plants. Mol. Plant 8 (2015), 1274–1284.
    • (2015) Mol. Plant , vol.8 , pp. 1274-1284
    • Ma, X.1    Zhang, Q.2    Zhu, Q.3    Liu, W.4    Chen, Y.5
  • 51
    • 79952302385 scopus 로고    scopus 로고
    • De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks
    • Mahfouz, M.M., Li, L., Shamimuzzaman, M., Wibowo, A., Fang, X., Zhu, J.K., De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks. Proc. Natl. Acad. Sci. U. S. A. 108 (2011), 2623–2628.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 2623-2628
    • Mahfouz, M.M.1    Li, L.2    Shamimuzzaman, M.3    Wibowo, A.4    Fang, X.5    Zhu, J.K.6
  • 52
    • 84891932593 scopus 로고    scopus 로고
    • Application of the CRISPR-Cas system for efficient genome engineering in plants
    • Mao, Y., Zhang, H., Xu, N., Zhang, B., Gou, F., Zhu, J., Application of the CRISPR-Cas system for efficient genome engineering in plants. Mol. Plant 6 (2013), 2008–2011.
    • (2013) Mol. Plant , vol.6 , pp. 2008-2011
    • Mao, Y.1    Zhang, H.2    Xu, N.3    Zhang, B.4    Gou, F.5    Zhu, J.6
  • 53
    • 84971507156 scopus 로고    scopus 로고
    • Precision targeted mutagenesis via Cas9 paired nickases in rice
    • Mikami, M., Toki, S., Endo, M., Precision targeted mutagenesis via Cas9 paired nickases in rice. Plant Cell Physiol. 57 (2016), 1058–1068.
    • (2016) Plant Cell Physiol. , vol.57 , pp. 1058-1068
    • Mikami, M.1    Toki, S.2    Endo, M.3
  • 54
    • 0034034401 scopus 로고    scopus 로고
    • Biological significance of a family of regularly spaced repeats in the genomes of Archaea, Bacteria and mitochondria
    • Mojica, F.J., Díez-Villaseñor, C., Soria, E., Juez, G., Biological significance of a family of regularly spaced repeats in the genomes of Archaea, Bacteria and mitochondria. Mol. Microbiol. 36 (2000), 244–246.
    • (2000) Mol. Microbiol. , vol.36 , pp. 244-246
    • Mojica, F.J.1    Díez-Villaseñor, C.2    Soria, E.3    Juez, G.4
  • 55
    • 64049118040 scopus 로고    scopus 로고
    • Short motif sequences determine the targets of the prokaryotic CRISPR defence system
    • Mojica, F.J.M., Díez-Villaseñor, C., García-Martínez, J., Almendros, C., Short motif sequences determine the targets of the prokaryotic CRISPR defence system. Microbiology 155 (2009), 733–740.
    • (2009) Microbiology , vol.155 , pp. 733-740
    • Mojica, F.J.M.1    Díez-Villaseñor, C.2    García-Martínez, J.3    Almendros, C.4
  • 56
    • 85011667995 scopus 로고    scopus 로고
    • Selective gene dosage by CRISPR-Cas9 genome editing in hexaploid Camelina sativa
    • Morineau, C., Bellec, Y., Tellier, F., Gissot, L., Kelemen, Z., et al. Selective gene dosage by CRISPR-Cas9 genome editing in hexaploid Camelina sativa. Plant Biotechnol. J., 2016, 10.1111/pbi.12671.
    • (2016) Plant Biotechnol. J.
    • Morineau, C.1    Bellec, Y.2    Tellier, F.3    Gissot, L.4    Kelemen, Z.5
  • 57
    • 84883828590 scopus 로고    scopus 로고
    • Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease
    • Nekrasov, V., Staskawicz, B., Weigel, D., Jones, J.D., Kamoun, S., Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease. Nat. Biotechnol. 31 (2013), 691–693.
    • (2013) Nat. Biotechnol. , vol.31 , pp. 691-693
    • Nekrasov, V.1    Staskawicz, B.2    Weigel, D.3    Jones, J.D.4    Kamoun, S.5
  • 58
    • 85016748230 scopus 로고    scopus 로고
    • Rapid generation of a transgene-free powdery mildew resistant tomato by genome deletion
    • Nekrasov, V., Wang, C., Win, J., Lanz, C., Weigel, D., et al. Rapid generation of a transgene-free powdery mildew resistant tomato by genome deletion. Sci. Rep., 7, 2017, 482.
    • (2017) Sci. Rep. , vol.7 , pp. 482
    • Nekrasov, V.1    Wang, C.2    Win, J.3    Lanz, C.4    Weigel, D.5
  • 59
    • 84998673639 scopus 로고    scopus 로고
    • CRISPR-Cas9: tool for qualitative and quantitative plant genome editing
    • Noman, A., Aqeel, M., He, S., CRISPR-Cas9: tool for qualitative and quantitative plant genome editing. Front. Plant Sci., 7, 2016, 1740.
    • (2016) Front. Plant Sci. , vol.7 , pp. 1740
    • Noman, A.1    Aqeel, M.2    He, S.3
  • 61
    • 84971280492 scopus 로고    scopus 로고
    • Optimization of CRISPR/Cas9 genome editing to modify abiotic stress responses in plants
    • Osakabe, Y., Watanabe, T., Sugano, S.S., Ueta, R., Ishihara, R., et al. Optimization of CRISPR/Cas9 genome editing to modify abiotic stress responses in plants. Sci. Rep., 6, 2016, 26685.
    • (2016) Sci. Rep. , vol.6 , pp. 26685
    • Osakabe, Y.1    Watanabe, T.2    Sugano, S.S.3    Ueta, R.4    Ishihara, R.5
  • 62
    • 84964688883 scopus 로고    scopus 로고
    • CRISPR/Cas9-mediated efficient and heritable targeted mutagenesis in tomato plants in the first and later generations
    • Pan, C., Ye, L., Qin, L., Liu, X., He, Y., et al. CRISPR/Cas9-mediated efficient and heritable targeted mutagenesis in tomato plants in the first and later generations. Sci. Rep., 6, 2016, 24765.
    • (2016) Sci. Rep. , vol.6 , pp. 24765
    • Pan, C.1    Ye, L.2    Qin, L.3    Liu, X.4    He, Y.5
  • 63
    • 84991721657 scopus 로고    scopus 로고
    • Genome-wide assessment of efficiency and specificity in CRISPR/Cas9 mediated multiple site targeting in Arabidopsis
    • Peterson, B.A., Haak, D.C., Nishimura, M.T., Teixeira, P.J., James, S.R., et al. Genome-wide assessment of efficiency and specificity in CRISPR/Cas9 mediated multiple site targeting in Arabidopsis. PLoS One, 11, 2016, e0162169.
    • (2016) PLoS One , vol.11
    • Peterson, B.A.1    Haak, D.C.2    Nishimura, M.T.3    Teixeira, P.J.4    James, S.R.5
  • 64
    • 84928212884 scopus 로고    scopus 로고
    • RNA-guided transcriptional regulation in planta via synthetic dCas9-based transcription factors
    • Piatek, A., Ali, Z., Baazim, H., Li, L., Abulfaraj, A., Al-Shareef, S., et al. RNA-guided transcriptional regulation in planta via synthetic dCas9-based transcription factors. Plant Biotechnol. J. 13 (2015), 578–589.
    • (2015) Plant Biotechnol. J. , vol.13 , pp. 578-589
    • Piatek, A.1    Ali, Z.2    Baazim, H.3    Li, L.4    Abulfaraj, A.5    Al-Shareef, S.6
  • 65
    • 0029946668 scopus 로고    scopus 로고
    • Two different but related mechanisms are used in plants for the repair of genomic double-strand breaks by homologous recombination
    • Puchta, H., Dujon, B., Hohn, B., Two different but related mechanisms are used in plants for the repair of genomic double-strand breaks by homologous recombination. Proc. Natl. Acad. Sci. U. S. A. 93 (1996), 5055–5060.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 5055-5060
    • Puchta, H.1    Dujon, B.2    Hohn, B.3
  • 66
    • 84901386271 scopus 로고    scopus 로고
    • Synthetic nucleases for genome engineering in plants: prospects for a bright future
    • Puchta, H., Fauser, F., Synthetic nucleases for genome engineering in plants: prospects for a bright future. Plant J. 78 (2014), 727–741.
    • (2014) Plant J. , vol.78 , pp. 727-741
    • Puchta, H.1    Fauser, F.2
  • 67
    • 84884288934 scopus 로고    scopus 로고
    • Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity
    • Ran, F.A., Hsu, P.D., Lin, C.Y., Gootenberg, J.S., Konermann, S., et al. Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell 154 (2013), 1380–1389.
    • (2013) Cell , vol.154 , pp. 1380-1389
    • Ran, F.A.1    Hsu, P.D.2    Lin, C.Y.3    Gootenberg, J.S.4    Konermann, S.5
  • 68
    • 84881255212 scopus 로고    scopus 로고
    • Spatial dynamics of chromosome translocations in living cells
    • Roukos, V., Voss, T.C., Schmidt, C.K., Lee, S., Wangsa, D., Misteli, T., Spatial dynamics of chromosome translocations in living cells. Science 341 (2013), 660–664.
    • (2013) Science , vol.341 , pp. 660-664
    • Roukos, V.1    Voss, T.C.2    Schmidt, C.K.3    Lee, S.4    Wangsa, D.5    Misteli, T.6
  • 69
    • 0032531757 scopus 로고    scopus 로고
    • Capture of genomic and T-DNA sequences during double-strand break repair in somatic plant cells
    • Salomon, S., Puchta, H., Capture of genomic and T-DNA sequences during double-strand break repair in somatic plant cells. EMBO. J. 17 (1998), 6086–6095.
    • (1998) EMBO. J. , vol.17 , pp. 6086-6095
    • Salomon, S.1    Puchta, H.2
  • 70
    • 84916624400 scopus 로고    scopus 로고
    • The CRISPR/Cas system can be used as nuclease for in planta gene targeting and as paired nickases for directed mutagenesis in Arabidopsis resulting in heritable progeny
    • Schiml, S., Fauser, F., Puchta, H., The CRISPR/Cas system can be used as nuclease for in planta gene targeting and as paired nickases for directed mutagenesis in Arabidopsis resulting in heritable progeny. Plant J. 80 (2014), 1139–1150.
    • (2014) Plant J. , vol.80 , pp. 1139-1150
    • Schiml, S.1    Fauser, F.2    Puchta, H.3
  • 71
    • 0030119272 scopus 로고    scopus 로고
    • Single-strand conformation polymorphism (SSCP) analysis: a convenient, rapid method for detection of single-base changes in DNA
    • Sekiya, T., Single-strand conformation polymorphism (SSCP) analysis: a convenient, rapid method for detection of single-base changes in DNA. Tanpakushitsu kakusan koso Protein, nucleic Acid. enzyme 41 (1996), 539–545.
    • (1996) Tanpakushitsu kakusan koso Protein, nucleic Acid. enzyme , vol.41 , pp. 539-545
    • Sekiya, T.1
  • 72
    • 84880737219 scopus 로고    scopus 로고
    • Rapid and efficient gene modification in rice and Brachypodium using TALENs
    • Shan, Q., Wang, Y., Chen, K., Liang, Z., Li, J., et al. Rapid and efficient gene modification in rice and Brachypodium using TALENs. Mol. Plant 6 (2013), 1365–1368.
    • (2013) Mol. Plant , vol.6 , pp. 1365-1368
    • Shan, Q.1    Wang, Y.2    Chen, K.3    Liang, Z.4    Li, J.5
  • 73
    • 84922910242 scopus 로고    scopus 로고
    • Genome editing in rice and wheat using the CRISPR/Cas system
    • Shan, Q., Wang, Y., Li, J., Gao, C., Genome editing in rice and wheat using the CRISPR/Cas system. Nat. Protoc. 9 (2014), 2395–2410.
    • (2014) Nat. Protoc. , vol.9 , pp. 2395-2410
    • Shan, Q.1    Wang, Y.2    Li, J.3    Gao, C.4
  • 74
    • 85018594542 scopus 로고    scopus 로고
    • Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion
    • Shimatani, Z., Kashojiya, S., Takayama, M., Terada, R., Arazoe, T., et al. Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion. Nat. Biotechnol. 35 (2017), 441–443.
    • (2017) Nat. Biotechnol. , vol.35 , pp. 441-443
    • Shimatani, Z.1    Kashojiya, S.2    Takayama, M.3    Terada, R.4    Arazoe, T.5
  • 75
    • 11144325580 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in randomly selected genes among japonica rice (Oryza sativa L.) varieties identified by PCR-RF-SSCP
    • Shirasawa, K., Monna, L., Kishitani, S., Nishio, T., Single nucleotide polymorphisms in randomly selected genes among japonica rice (Oryza sativa L.) varieties identified by PCR-RF-SSCP. DNA Res. 11 (2004), 275–283.
    • (2004) DNA Res. , vol.11 , pp. 275-283
    • Shirasawa, K.1    Monna, L.2    Kishitani, S.3    Nishio, T.4
  • 76
    • 0036016441 scopus 로고    scopus 로고
    • Efficient repair of genomic double-strand breaks by homologous recombination between directly repeated sequences in the plant genome
    • Siebert, R., Puchta, H., Efficient repair of genomic double-strand breaks by homologous recombination between directly repeated sequences in the plant genome. Plant Cell. 14 (2002), 1121–1131.
    • (2002) Plant Cell. , vol.14 , pp. 1121-1131
    • Siebert, R.1    Puchta, H.2
  • 77
    • 84930651072 scopus 로고    scopus 로고
    • Targeted mutagenesis in soybean using the CRISPR-Cas9 system
    • Sun, X., Hu, Z., Chen, R., Jiang, Q., Song, G., et al. Targeted mutagenesis in soybean using the CRISPR-Cas9 system. Sci. Rep., 5, 2015, 10342.
    • (2015) Sci. Rep. , vol.5 , pp. 10342
    • Sun, X.1    Hu, Z.2    Chen, R.3    Jiang, Q.4    Song, G.5
  • 78
    • 85014906772 scopus 로고    scopus 로고
    • Generation of high-amylose rice through CRISPR/Cas9-mediated targeted mutagenesis of starch branching enzymes
    • Sun, Y., Jiao, G., Liu, Z., Zhang, X., Li, J., et al. Generation of high-amylose rice through CRISPR/Cas9-mediated targeted mutagenesis of starch branching enzymes. Front. Plant Sci., 8, 2017, 298.
    • (2017) Front. Plant Sci. , vol.8 , pp. 298
    • Sun, Y.1    Jiao, G.2    Liu, Z.3    Zhang, X.4    Li, J.5
  • 79
    • 84995550201 scopus 로고    scopus 로고
    • A Genome editing in maize directed by CRISPR-Cas9 ribonucleoprotein complexes
    • Svitashev, S., Schwartz, C., Lenderts, B., Young, J.K., Mark, C., A Genome editing in maize directed by CRISPR-Cas9 ribonucleoprotein complexes. Nat. Commun., 7, 2016, 13274.
    • (2016) Nat. Commun. , vol.7 , pp. 13274
    • Svitashev, S.1    Schwartz, C.2    Lenderts, B.3    Young, J.K.4    Mark, C.5
  • 80
    • 84942901283 scopus 로고    scopus 로고
    • Targeted mutagenesis, precise gene editing, and site-specific gene insertion in maize using Cas9 and guide RNA
    • Svitashev, S., Young, J.K., Schwartz, C., Gao, H., Falco, S.C., Cigan, A.M., Targeted mutagenesis, precise gene editing, and site-specific gene insertion in maize using Cas9 and guide RNA. Plant Physiol. 169 (2015), 931–945.
    • (2015) Plant Physiol. , vol.169 , pp. 931-945
    • Svitashev, S.1    Young, J.K.2    Schwartz, C.3    Gao, H.4    Falco, S.C.5    Cigan, A.M.6
  • 81
    • 85013304812 scopus 로고    scopus 로고
    • A CRISPR-Cpf1 system for efficient genome editing and transcriptional repression in plants
    • Tang, X., Lowder, L.G., Zhang, T., Malzahn, A.A., Zheng, X., et al. A CRISPR-Cpf1 system for efficient genome editing and transcriptional repression in plants. Nat. Plants, 3, 2017, 17018.
    • (2017) Nat. Plants , vol.3 , pp. 17018
    • Tang, X.1    Lowder, L.G.2    Zhang, T.3    Malzahn, A.A.4    Zheng, X.5
  • 82
    • 84949100864 scopus 로고    scopus 로고
    • Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements
    • Thakore, P.I., D'ippolito, A.M., Song, L., Safi, A., Shivakumar, N.K., et al. Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements. Nat. Methods 12 (2015), 1143–1149.
    • (2015) Nat. Methods , vol.12 , pp. 1143-1149
    • Thakore, P.I.1    D'ippolito, A.M.2    Song, L.3    Safi, A.4    Shivakumar, N.K.5
  • 83
    • 85006355621 scopus 로고    scopus 로고
    • Efficient CRISPR/Cas9-based gene knockout in watermelon
    • Tian, S., Jiang, L., Gao, Q., Zhang, J., Zong, M., et al. Efficient CRISPR/Cas9-based gene knockout in watermelon. Plant Cell Rep. 36 (2016), 399–406.
    • (2016) Plant Cell Rep. , vol.36 , pp. 399-406
    • Tian, S.1    Jiang, L.2    Gao, Q.3    Zhang, J.4    Zong, M.5
  • 84
    • 66249093890 scopus 로고    scopus 로고
    • High-frequency modification of plant genes using engineered zinc-finger nucleases
    • Townsend, J.A., Wright, D.A., Winfrey, R.J., Fu, F., Maeder, M.L., et al. High-frequency modification of plant genes using engineered zinc-finger nucleases. Nature 459 (2009), 442–445.
    • (2009) Nature , vol.459 , pp. 442-445
    • Townsend, J.A.1    Wright, D.A.2    Winfrey, R.J.3    Fu, F.4    Maeder, M.L.5
  • 85
    • 84902204289 scopus 로고    scopus 로고
    • Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing
    • Tsai, S.Q., Wyvekens, N., Khayter, C., Foden, J.A., Thapar, V., et al. Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing. Nat. Biotechnol. 32 (2014), 569–576.
    • (2014) Nat. Biotechnol. , vol.32 , pp. 569-576
    • Tsai, S.Q.1    Wyvekens, N.2    Khayter, C.3    Foden, J.A.4    Thapar, V.5
  • 86
    • 84890831873 scopus 로고    scopus 로고
    • RNA-guided genome editing for target gene mutations in wheat
    • Upadhyay, S.K., Kumar, J., Alok, A., Tuli, R., RNA-guided genome editing for target gene mutations in wheat. G3 (Bethesda) 3 (2013), 2233–2238.
    • (2013) G3 (Bethesda) , vol.3 , pp. 2233-2238
    • Upadhyay, S.K.1    Kumar, J.2    Alok, A.3    Tuli, R.4
  • 87
    • 79955584258 scopus 로고    scopus 로고
    • It is a long way to GM agriculture
    • Van Montagu, M., It is a long way to GM agriculture. Annu. Rev. Plant Biol. 62 (2011), 1–23.
    • (2011) Annu. Rev. Plant Biol. , vol.62 , pp. 1-23
    • Van Montagu, M.1
  • 88
    • 84924666891 scopus 로고    scopus 로고
    • Comparison of T7E1 and surveyor mismatch cleavage assays to detect mutations triggered by engineered nucleases
    • Vouillot, L., Thélie, A., Pollet, N., Comparison of T7E1 and surveyor mismatch cleavage assays to detect mutations triggered by engineered nucleases. G3 (Bethesda) 5 (2015), 407–415.
    • (2015) G3 (Bethesda) , vol.5 , pp. 407-415
    • Vouillot, L.1    Thélie, A.2    Pollet, N.3
  • 89
    • 84903317244 scopus 로고    scopus 로고
    • Precision genome engineering and agriculture: opportunities and regulatory challenges
    • Voytas, D.F., Gao, C., Precision genome engineering and agriculture: opportunities and regulatory challenges. PLoS Biol., 12, 2014, e1001877.
    • (2014) PLoS Biol. , vol.12
    • Voytas, D.F.1    Gao, C.2
  • 90
    • 84977500985 scopus 로고    scopus 로고
    • Enhanced rice blast resistance by CRISPR/Cas9-targeted mutagenesis of the ERF transcription factor gene OsERF922
    • Wang, F., Wang, C., Liu, P., Lei, C., Hao, W., et al. Enhanced rice blast resistance by CRISPR/Cas9-targeted mutagenesis of the ERF transcription factor gene OsERF922. PLoS One, 11, 2016, e0154027.
    • (2016) PLoS One , vol.11
    • Wang, F.1    Wang, C.2    Liu, P.3    Lei, C.4    Hao, W.5
  • 91
    • 84921934205 scopus 로고    scopus 로고
    • Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew
    • Wang, Y., Cheng, X., Shan, Q., Zhang, Y., Liu, J., et al. Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew. Nat. Biotechnol. 32 (2014), 947–951.
    • (2014) Nat. Biotechnol. , vol.32 , pp. 947-951
    • Wang, Y.1    Cheng, X.2    Shan, Q.3    Zhang, Y.4    Liu, J.5
  • 92
    • 84937568562 scopus 로고    scopus 로고
    • Egg cell-specific promoter-controlled CRISPR/Cas9 efficiently generates homozygous mutants for multiple target genes in Arabidopsis in a single generation
    • Wang, Z., Xing, H., Dong, L., Zhang, H., Han, C., et al. Egg cell-specific promoter-controlled CRISPR/Cas9 efficiently generates homozygous mutants for multiple target genes in Arabidopsis in a single generation. Genome Biol., 16, 2015, 144.
    • (2015) Genome Biol. , vol.16 , pp. 144
    • Wang, Z.1    Xing, H.2    Dong, L.3    Zhang, H.4    Han, C.5
  • 93
    • 84939191325 scopus 로고    scopus 로고
    • Use of designer nucleases for targeted gene and genome editing in plants
    • Weeks, D.P., Spalding, M.H., Yang, B., Use of designer nucleases for targeted gene and genome editing in plants. Plant Biotechnol. J. 14 (2015), 483–495.
    • (2015) Plant Biotechnol. J. , vol.14 , pp. 483-495
    • Weeks, D.P.1    Spalding, M.H.2    Yang, B.3
  • 94
    • 84947255513 scopus 로고    scopus 로고
    • DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins
    • Woo, J.W., Kim, J., Kwon, S.I., Corvalán, C., Cho, S.W., et al. DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins. Nat. Biotechnol. 33 (2015), 1162–1164.
    • (2015) Nat. Biotechnol. , vol.33 , pp. 1162-1164
    • Woo, J.W.1    Kim, J.2    Kwon, S.I.3    Corvalán, C.4    Cho, S.W.5
  • 95
    • 84925262435 scopus 로고    scopus 로고
    • Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system
    • Xie, K., Minkenberg, B., Yang, Y., Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system. Proc. Natl. Acad. Sci. U. S. A. 112 (2015), 3570–3575.
    • (2015) Proc. Natl. Acad. Sci. U. S. A. , vol.112 , pp. 3570-3575
    • Xie, K.1    Minkenberg, B.2    Yang, Y.3
  • 96
    • 84884962826 scopus 로고    scopus 로고
    • RNA-guided genome editing in plants using a CRISPR-Cas system
    • Xie, K., Yang, Y., RNA-guided genome editing in plants using a CRISPR-Cas system. Mol. Plant 6 (2013), 1975–1983.
    • (2013) Mol. Plant , vol.6 , pp. 1975-1983
    • Xie, K.1    Yang, Y.2
  • 97
    • 84964313841 scopus 로고    scopus 로고
    • A CRISPR/Cas9 toolkit for multiplex genome editing in plants
    • Xing, H.L., Dong, L., Wang, Z.P., Zhang, H.Y., et al. A CRISPR/Cas9 toolkit for multiplex genome editing in plants. BMC Plant Biol., 14, 2014, 327.
    • (2014) BMC Plant Biol. , vol.14 , pp. 327
    • Xing, H.L.1    Dong, L.2    Wang, Z.P.3    Zhang, H.Y.4
  • 98
    • 84938551842 scopus 로고    scopus 로고
    • Gene targeting using the Agrobacterium tumefaciens-mediated CRISPR-Cas system in rice
    • Xu, R., Li, H., Qin, R., Wang, L., Li, L., Wei, P., Yang, J., Gene targeting using the Agrobacterium tumefaciens-mediated CRISPR-Cas system in rice. Rice, 7, 2014, 5.
    • (2014) Rice , vol.7 , pp. 5
    • Xu, R.1    Li, H.2    Qin, R.3    Wang, L.4    Li, L.5    Wei, P.6    Yang, J.7
  • 99
    • 85011091298 scopus 로고    scopus 로고
    • Generation of targeted mutant rice using a CRISPR-Cpf1 system
    • Xu, R., Qin, R., Li, H., Li, D., Li, L., et al. Generation of targeted mutant rice using a CRISPR-Cpf1 system. Plant Biotechnol. J., 2016, 1–5.
    • (2016) Plant Biotechnol. J. , pp. 1-5
    • Xu, R.1    Qin, R.2    Li, H.3    Li, D.4    Li, L.5
  • 100
    • 84947723842 scopus 로고    scopus 로고
    • High-efficiency genome editing in Arabidopsis using YAO promoter-driven CRISPR/Cas9 system
    • Yan, L., Wei, S., Wu, Y., Hu, R., Li, H., et al. High-efficiency genome editing in Arabidopsis using YAO promoter-driven CRISPR/Cas9 system. Mol. Plant 8 (2015), 1820–1823.
    • (2015) Mol. Plant , vol.8 , pp. 1820-1823
    • Yan, L.1    Wei, S.2    Wu, Y.3    Hu, R.4    Li, H.5
  • 101
    • 84943602335 scopus 로고    scopus 로고
    • A geminivirus-based guide RNA delivery system for CRISPR/Cas9 mediated plant genome editing
    • Yin, K., Han, T., Liu, G., Chen, T., Wang, Y., et al. A geminivirus-based guide RNA delivery system for CRISPR/Cas9 mediated plant genome editing. Sci. Rep., 5, 2015, 14926.
    • (2015) Sci. Rep. , vol.5 , pp. 14926
    • Yin, K.1    Han, T.2    Liu, G.3    Chen, T.4    Wang, Y.5
  • 102
    • 84975678715 scopus 로고    scopus 로고
    • Cpf1 is a single RNA-guided endonuclease of a Class 2 CRISPR-Cas system
    • Zetsche, B., Gootenberg, J.S., Abudayyeh, O.O., Slaymaker, I.M., Makarova, K.S., et al. Cpf1 is a single RNA-guided endonuclease of a Class 2 CRISPR-Cas system. Cell 163 (2015), 759–771.
    • (2015) Cell , vol.163 , pp. 759-771
    • Zetsche, B.1    Gootenberg, J.S.2    Abudayyeh, O.O.3    Slaymaker, I.M.4    Makarova, K.S.5
  • 103
    • 84988940483 scopus 로고    scopus 로고
    • Genome editing: new antiviral weapon for plants
    • Zhang, D.D., Li, Z.X., Li, J.F., Genome editing: new antiviral weapon for plants. Nat. Plants, 1, 2015, 15146.
    • (2015) Nat. Plants , vol.1 , pp. 15146
    • Zhang, D.D.1    Li, Z.X.2    Li, J.F.3
  • 104
    • 84904639258 scopus 로고    scopus 로고
    • The CRISPR/Cas9 system produces specific and homozygous targeted gene editing in rice in one generation
    • Zhang, H., Zhang, J., Wei, P., Zhang, B., Gou, F., et al. The CRISPR/Cas9 system produces specific and homozygous targeted gene editing in rice in one generation. Plant Biotechnol. J. 12 (2014), 797–807.
    • (2014) Plant Biotechnol. J. , vol.12 , pp. 797-807
    • Zhang, H.1    Zhang, J.2    Wei, P.3    Zhang, B.4    Gou, F.5
  • 105
    • 84983783288 scopus 로고    scopus 로고
    • Efficient and transgene-free genome editing in wheat through transient expression of CRISPR/Cas9 DNA or RNA
    • Zhang, Y., Liang, Z., Zong, Y., Wang, Y., Liu, J., et al. Efficient and transgene-free genome editing in wheat through transient expression of CRISPR/Cas9 DNA or RNA. Nat. Commun., 7, 2016, 12617.
    • (2016) Nat. Commun. , vol.7 , pp. 12617
    • Zhang, Y.1    Liang, Z.2    Zong, Y.3    Wang, Y.4    Liu, J.5
  • 106
    • 84949557262 scopus 로고    scopus 로고
    • A multiplex CRISPR/Cas9 platform for fast and efficient editing of multiple genes in Arabidopsis
    • Zhang, Z., Mao, Y., Ha, S., Liu, W., Botella, J.R., Zhu, J.K., A multiplex CRISPR/Cas9 platform for fast and efficient editing of multiple genes in Arabidopsis. Plant Cell Rep. 35 (2016), 1519–1533.
    • (2016) Plant Cell Rep. , vol.35 , pp. 1519-1533
    • Zhang, Z.1    Mao, Y.2    Ha, S.3    Liu, W.4    Botella, J.R.5    Zhu, J.K.6
  • 107
    • 84961774687 scopus 로고    scopus 로고
    • Effective screen of CRISPR/Cas9-induced mutants in rice by single-strand conformation polymorphism
    • Zheng, X., Yang, S., Zhang, D., Zhong, Z., Tang, X., et al. Effective screen of CRISPR/Cas9-induced mutants in rice by single-strand conformation polymorphism. Plant Cell Rep. 35 (2016), 1545–1554.
    • (2016) Plant Cell Rep. , vol.35 , pp. 1545-1554
    • Zheng, X.1    Yang, S.2    Zhang, D.3    Zhong, Z.4    Tang, X.5
  • 108
    • 84996802204 scopus 로고    scopus 로고
    • Development of commercial thermo-sensitive genic male sterile rice accelerates hybrid rice breeding using the CRISPR/Cas9-mediated TMS5 editing system
    • Zhou, H., He, M., Li, J., Chen, L., Huang, Z., et al. Development of commercial thermo-sensitive genic male sterile rice accelerates hybrid rice breeding using the CRISPR/Cas9-mediated TMS5 editing system. Sci. Rep., 6, 2016, 37395.
    • (2016) Sci. Rep. , vol.6 , pp. 37395
    • Zhou, H.1    He, M.2    Li, J.3    Chen, L.4    Huang, Z.5
  • 109
    • 84942827085 scopus 로고    scopus 로고
    • Exploiting SNPs for biallelic CRISPR mutations in the outcrossing woody perennial Populus reveals 4-coumarate: CoA ligase specificity and redundancy
    • Zhou, X., Jacobs, T.B., Xue, L.J., Harding, S.A., Tsai, C.J., Exploiting SNPs for biallelic CRISPR mutations in the outcrossing woody perennial Populus reveals 4-coumarate: CoA ligase specificity and redundancy. New Phytol. 208 (2015), 298–301.
    • (2015) New Phytol. , vol.208 , pp. 298-301
    • Zhou, X.1    Jacobs, T.B.2    Xue, L.J.3    Harding, S.A.4    Tsai, C.J.5
  • 110
    • 84957838490 scopus 로고    scopus 로고
    • Efficiency and inheritance of targeted mutagenesis in maize using CRISPR-Cas9
    • Zhu, J., Song, N., Sun, S., Yang, W., Zhao, H., et al. Efficiency and inheritance of targeted mutagenesis in maize using CRISPR-Cas9. J. Genet. Genomics 43 (2016), 25–36.
    • (2016) J. Genet. Genomics , vol.43 , pp. 25-36
    • Zhu, J.1    Song, N.2    Sun, S.3    Yang, W.4    Zhao, H.5
  • 111
    • 84923229919 scopus 로고    scopus 로고
    • An efficient genotyping method for genome-modified animals and human cells generated with CRISPR/Cas9 system
    • Zhu, X., Xu, Y., Yu, S., Lu, L., Ding, M., et al. An efficient genotyping method for genome-modified animals and human cells generated with CRISPR/Cas9 system. Sci. Rep., 4, 2014, 6420.
    • (2014) Sci. Rep. , vol.4 , pp. 6420
    • Zhu, X.1    Xu, Y.2    Yu, S.3    Lu, L.4    Ding, M.5
  • 112
    • 85018618268 scopus 로고    scopus 로고
    • Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion
    • Zong, Y., Wang, Y., Li, C., Zhang, R., Chen, K., et al. Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion. Nat. Biotechnol. 35 (2017), 438–440.
    • (2017) Nat. Biotechnol. , vol.35 , pp. 438-440
    • Zong, Y.1    Wang, Y.2    Li, C.3    Zhang, R.4    Chen, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.