Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion

Nature Biotechnology

Volumn 35, Issue 5, 2017, Pages 438-440

  Zong, Yuan ^a,b   Wang, Yanpeng ^a,b   Li, Chao ^a,b   Zhang, Rui ^a   Chen, Kunling ^a   Ran, Yidong ^c   Qiu, Jin Long ^a   Wang, Daowen ^a   Gao, Caixia ^a  

^a INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c Genovo Biotechnology Co Ltd   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYTIDINE DEAMINASE; DNA DONORS; DOUBLE STRANDED DNA; GENOME MODIFICATION; MAIZE PLANTS;

BIOTECHNOLOGY;

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 1; CRISPR CAS9 NICKASE CYTIDINE DEAMINASE FUSION PROTEIN; CYTOSINE; HYBRID PROTEIN; THYMINE; UNCLASSIFIED DRUG; CASPASE 9; CRISPR ASSOCIATED PROTEIN; CYTIDINE DEAMINASE; PLANT DNA;

ARTICLE; CONTROLLED STUDY; CRISPR CAS SYSTEM; GENE CONVERSION; GENE EDITING; GENE TARGETING; MAIZE; NONHUMAN; PLANT GENE; PLANT REGENERATION; PRIORITY JOURNAL; PROTOPLAST; RICE; WHEAT; BASE PAIRING; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; GENETICS; ORYZA; PLANT; POINT MUTATION; PROCEDURES; SITE DIRECTED MUTAGENESIS; TRANSGENIC PLANT;

BASE PAIRING; CASPASE 9; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-ASSOCIATED PROTEINS; CYTIDINE DEAMINASE; DNA, PLANT; GENE EDITING; GENES, PLANT; MUTAGENESIS, SITE-DIRECTED; ORYZA; PLANTS; PLANTS, GENETICALLY MODIFIED; POINT MUTATION; RECOMBINANT FUSION PROTEINS; TRITICUM; ZEA MAYS;

EID: 85018618268     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.3811     Document Type: Article

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