Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion

Nature Biotechnology

Volumn 35, Issue 5, 2017, Pages 441-443

  Shimatani, Zenpei ^a   Kashojiya, Sachiko ^b   Takayama, Mariko ^b   Terada, Rie ^c   Arazoe, Takayuki ^a   Ishii, Hisaki ^a   Teramura, Hiroshi ^a   Yamamoto, Tsuyoshi ^b   Komatsu, Hiroki ^b   Miura, Kenji ^b   Ezura, Hiroshi ^b   Nishida, Keiji ^a   Ariizumi, Tohru ^b   Kondo, Akihiko ^a  

^a KOBE UNIVERSITY   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c MEIJO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CROPS; HERBICIDES; NUCLEIC ACIDS; PLANTS (BOTANY); WEED CONTROL;

ACTIVATION INDUCED CYTIDINE DEAMINASE; CROP IMPROVEMENT; CYTIDINE DEAMINASE; GENOMIC REGIONS; HERBICIDE RESISTANCE; MARKER-FREE; POINT MUTAGENESIS; POINT MUTATIONS;

FRUITS;

ACTIVATION INDUCED CYTIDINE DEAMINASE; CYTIDINE DEAMINASE; DNA; GUIDE RNA; HERBICIDE; CASPASE 9; CRISPR ASSOCIATED PROTEIN; HYBRID PROTEIN; PLANT DNA;

ARTICLE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; GENOMICS; MUTAGENESIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; RICE; TOMATO; BASE PAIRING; GENE EDITING; GENETICS; ORYZA; PLANT GENE; PROCEDURES; SITE DIRECTED MUTAGENESIS; TRANSGENIC PLANT;

BASE PAIRING; CASPASE 9; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-ASSOCIATED PROTEINS; CYTIDINE DEAMINASE; DNA, PLANT; GENE EDITING; GENES, PLANT; LYCOPERSICON ESCULENTUM; MUTAGENESIS, SITE-DIRECTED; ORYZA; PLANTS, GENETICALLY MODIFIED; POINT MUTATION; RECOMBINANT FUSION PROTEINS;

EID: 85018594542     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.3833     Document Type: Article

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