-
1
-
-
84857097177
-
RNA-guided genetic silencing systems in bacteria and archaea
-
Wiedenheft, B., Sternberg, S. H. & Doudna, J. A. RNA-guided genetic silencing systems in bacteria and archaea. Nature 482, 331-338 (2012
-
(2012)
Nature
, vol.482
, pp. 331-338
-
-
Wiedenheft, B.1
Sternberg, S.H.2
Doudna, J.A.3
-
2
-
-
0037510038
-
Enhancing gene targeting with designed zinc finger nucleases
-
DOI 10.1126/science.1079512
-
Bibikova, M., Beumer, K., Trautman, J. K. & Carroll, D. Enhancing gene targeting with designed zinc finger nucleases. Science 300, 764 (2003 (Pubitemid 36532104)
-
(2003)
Science
, vol.300
, Issue.5620
, pp. 764
-
-
Bibikova, M.1
Beumer, K.2
Trautman, J.K.3
Carroll, D.4
-
3
-
-
0038523969
-
Chimeric nucleases stimulate gene targeting in human cells
-
DOI 10.1126/science.1078395
-
Porteus, M. H. & Baltimore, D. Chimeric nucleases stimulate gene targeting in human cells. Science 300, 763 (2003 (Pubitemid 36532103)
-
(2003)
Science
, vol.300
, Issue.5620
, pp. 763
-
-
Porteus, M.H.1
Baltimore, D.2
-
4
-
-
74949133880
-
Targeted chromosomal deletions in human cells using zinc finger nucleases
-
Lee, H. J., Kim, E. & Kim, J. S. Targeted chromosomal deletions in human cells using zinc finger nucleases. Genome Res. 20, 81-89 (2010
-
(2010)
Genome Res
, vol.20
, pp. 81-89
-
-
Lee, H.J.1
Kim, E.2
Kim, J.S.3
-
5
-
-
84863275797
-
Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases
-
Lee, H. J., Kweon, J., Kim, E., Kim, S. & Kim, J. S. Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases. Genome Res. 22, 539-548 (2012
-
(2012)
Genome Res
, vol.22
, pp. 539-548
-
-
Lee, H.J.1
Kweon, J.2
Kim, E.3
Kim, S.4
Kim, J.S.5
-
6
-
-
84884165315
-
DNA targeting specificity of RNA-guided Cas9 nucleases
-
Hsu, P. D. et al. DNA targeting specificity of RNA-guided Cas9 nucleases. Nat. Biotechnol. 31, 827-832 (2013
-
(2013)
Nat. Biotechnol
, vol.31
, pp. 827-832
-
-
Hsu, P.D.1
-
7
-
-
84865070369
-
A programmable dual-rna-guided dna endonuclease in adaptive bacterial immunity
-
Jinek, M. et al. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337, 816-821 (2012
-
(2012)
Science
, vol.337
, pp. 816-821
-
-
Jinek, M.1
-
8
-
-
84874608929
-
RNA-guided editing of bacterial genomes using CRISPR-Cas systems
-
Jiang, W., Bikard, D., Cox, D., Zhang, F. & Marraffini, L. A. RNA-guided editing of bacterial genomes using CRISPR-Cas systems. Nat. Biotechnol. 31, 233-239 (2013
-
(2013)
Nat. Biotechnol
, vol.31
, pp. 233-239
-
-
Jiang, W.1
Bikard, D.2
Cox, D.3
Zhang, F.4
Marraffini, L.A.5
-
9
-
-
84874624936
-
Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease
-
Cho, S. W., Kim, S., Kim, J. M. & Kim, J. S. Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease. Nat. Biotechnol. 31, 230-232 (2013
-
(2013)
Nat. Biotechnol
, vol.31
, pp. 230-232
-
-
Cho, S.W.1
Kim, S.2
Kim, J.M.3
Kim, J.S.4
-
10
-
-
84873729095
-
Multiplex genome engineering using crispr/cas systems
-
Cong, L. et al. Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819-823 (2013
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
-
11
-
-
84873734105
-
Rna-guided human genome engineering via cas9
-
Mali, P. et al. RNA-guided human genome engineering via Cas9. Science 339, 823-826 (2013
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali, P.1
-
12
-
-
84876567971
-
RNA-programmed genome editing in human cells
-
Jinek, M. et al. RNA-programmed genome editing in human cells. eLife 2, e00471 (2013
-
(2013)
ELife
, vol.2
-
-
Jinek, M.1
-
13
-
-
84874617789
-
Efficient genome editing in zebrafish using a crispr-cas system
-
Hwang, W. Y. et al. Efficient genome editing in zebrafish using a CRISPR-Cas system. Nat. Biotechnol. 31, 227-229 (2013
-
(2013)
Nat. Biotechnol
, vol.31
, pp. 227-229
-
-
Hwang, W.Y.1
-
14
-
-
84880088705
-
Genome engineering of drosophila with the crispr rna-guided cas9 nuclease
-
Gratz, S. J. et al. Genome engineering of Drosophila with the CRISPR RNA-guided Cas9 nuclease. Genetics 194, 1029-1035 (2013
-
(2013)
Genetics
, vol.194
, pp. 1029-1035
-
-
Gratz, S.J.1
-
15
-
-
84877707375
-
One-step generation of mice carrying mutations in multiple genes by crispr/cas-mediated genome engineering
-
Wang, H. et al. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-Mediated genome engineering. Cell 153, 910-918 (2013
-
(2013)
Cell
, vol.153
, pp. 910-918
-
-
Wang, H.1
-
16
-
-
84876409836
-
Genome editing with rna-guided cas9 nuclease in zebrafish embryos
-
Chang, N. et al. Genome editing with RNA-guided Cas9 nuclease in zebrafish embryos. Cell Res. 23, 465-472
-
Cell Res
, vol.23
, pp. 465-472
-
-
Chang, N.1
-
17
-
-
84877103949
-
Generation of gene-modified mice via Cas9/RNA-mediated gene targeting
-
Shen, B. et al. Generation of gene-modified mice via Cas9/RNA-mediated gene targeting. Cell Res. 23, 720-723
-
Cell Res
, vol.23
, pp. 720-723
-
-
Shen, B.1
-
18
-
-
84884911076
-
Heritable gene knockout in Caenorhabditis elegans by direct injection of Cas9-sgRNA ribonucleoproteins
-
Cho, S. W., Lee, J., Carroll, D. & Kim, J. S. Heritable gene knockout in Caenorhabditis elegans by direct injection of Cas9-sgRNA ribonucleoproteins. Genetics 195, 1177-1180 (2013
-
(2013)
Genetics
, vol.195
, pp. 1177-1180
-
-
Cho, S.W.1
Lee, J.2
Carroll, D.3
Kim, J.S.4
-
19
-
-
84891704542
-
Highly efficient gene knockout in mice and zebrafish with RNA-guied endonucleases
-
doi: 10.1101/gr.163394.113
-
Sung, Y. H. et al. Highly efficient gene knockout in mice and zebrafish with RNA-guied endonucleases. Genome Res. doi: 10.1101/gr.163394.113 (2013
-
(2013)
Genome Res
-
-
Sung, Y.H.1
-
20
-
-
85042815594
-
Targeted genome modification of crop plants using a CRISPR-Cas system
-
Shan, Q. et al. Targeted genome modification of crop plants using a CRISPR-Cas system. Nat. Biotechnol. 31, 686-688 (2013
-
(2013)
Nat. Biotechnol
, vol.31
, pp. 686-688
-
-
Shan, Q.1
-
21
-
-
84883785822
-
Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9
-
Li, J. F. et al. Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9. Nat. Biotechnol. 31, 688-691 (2013
-
(2013)
Nat. Biotechnol
, vol.31
, pp. 688-691
-
-
Li, J.F.1
-
22
-
-
84883828590
-
Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease
-
Nekrasov, V., Staskawicz, B., Weigel, D., Jones, J. D. & Kamoun, S. Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease. Nat. Biotechnol. 31, 691-693 (2013
-
(2013)
Nat. Biotechnol
, vol.31
, pp. 691-693
-
-
Nekrasov, V.1
Staskawicz, B.2
Weigel, D.3
Jones, J.D.4
Kamoun, S.5
-
23
-
-
67650045497
-
Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly
-
Kim, H. J., Lee, H. J., Kim, H., Cho, S. W. & Kim, J. S. Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly. Genome Res. 19, 1279-1288 (2009
-
(2009)
Genome Res
, vol.19
, pp. 1279-1288
-
-
Kim, H.J.1
Lee, H.J.2
Kim, H.3
Cho, S.W.4
Kim, J.S.5
-
24
-
-
18944373328
-
Highly efficient endogenous human gene correction using designed zinc-finger nucleases
-
DOI 10.1038/nature03556
-
Urnov, F. D. et al. Highly efficient endogenous human gene correction using designed zinc-finger nucleases. Nature 435, 646-651 (2005 (Pubitemid 40825505)
-
(2005)
Nature
, vol.435
, Issue.7042
, pp. 646-651
-
-
Urnov, F.D.1
Miller, J.C.2
Lee, Y.-L.3
Beausejour, C.M.4
Rock, J.M.5
Augustus, S.6
Jamieson, A.C.7
Porteus, M.H.8
Gregory, P.D.9
Holmes, M.C.10
-
25
-
-
80255134581
-
Surrogate reporters for enrichment of cells with nuclease-induced mutations
-
Kim, H., Um, E., Cho, S. R., Jung, C. & Kim, J. S. Surrogate reporters for enrichment of cells with nuclease-induced mutations. Nat. Methods 8, 941-943 (2011
-
(2011)
Nat. Methods
, vol.8
, pp. 941-943
-
-
Kim, H.1
Um, E.2
Cho, S.R.3
Jung, C.4
Kim, J.S.5
-
26
-
-
84866156176
-
Simple methods for generating and detecting locus-specific mutations induced with talens in the zebrafish genome
-
Dahlem, T. J. et al. Simple methods for generating and detecting locus-specific mutations induced with TALENs in the zebrafish genome. PLoS Genet. 8, e1002861 (2012
-
(2012)
PLoS Genet
, vol.8
-
-
Dahlem, T.J.1
-
27
-
-
84872194963
-
Knockout mice created by talen-mediated gene targeting
-
Sung, Y. H. et al. Knockout mice created by TALEN-mediated gene targeting. Nat. Biotechnol. 31, 23-24 (2013
-
(2013)
Nat. Biotechnol
, vol.31
, pp. 23-24
-
-
Sung, Y.H.1
-
28
-
-
78650855391
-
Preassembled zinc-finger arrays for rapid construction of zfns
-
Kim, S., Lee, M. J., Kim, H., Kang, M. & Kim, J. S. Preassembled zinc-finger arrays for rapid construction of ZFNs. Nat. Methods 8, 7 (2011
-
(2011)
Nat. Methods
, vol.8
, Issue.7
-
-
Kim, S.1
Lee, M.J.2
Kim, H.3
Kang, M.4
Kim, J.S.5
-
29
-
-
84875157258
-
A library of TAL effector nucleases spanning the human genome
-
Kim, Y. et al. A library of TAL effector nucleases spanning the human genome. Nat. Biotechnol. 31, 251-258 (2013
-
(2013)
Nat. Biotechnol
, vol.31
, pp. 251-258
-
-
Kim, Y.1
-
30
-
-
0037062430
-
Targeted inactivation of CTNNB1 reveals unexpected effects of β-catenin mutation
-
DOI 10.1073/pnas.082240999
-
Chan, T. A., Wang, Z., Dang, L. H., Vogelstein, B. & Kinzler, K. W. Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation. Proc. Natl Acad. Sci. USA 99, 8265-8270 (2002 (Pubitemid 34651041)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.12
, pp. 8265-8270
-
-
Chan, T.A.1
Wang, Z.2
Dang, L.H.3
Vogelstein, B.4
Kinzler, K.W.5
-
31
-
-
16044373004
-
Resistance to hiv-1 infection in caucasian individuals bearing mutant alleles of the ccr-5 chemokine receptor gene
-
Samson, M. et al. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 382, 722-725 (1996
-
(1996)
Nature
, vol.382
, pp. 722-725
-
-
Samson, M.1
-
32
-
-
75549087826
-
Cosmic (the catalogue of somatic mutations in cancer): A resource to investigate acquired mutations in human cancer
-
Forbes, S. A. et al. COSMIC (the Catalogue of Somatic Mutations in Cancer): A resource to investigate acquired mutations in human cancer. Nucleic Acids Res. 38, D652-D657 (2010
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Forbes, S.A.1
-
33
-
-
84891710947
-
Analysis of off-Target effects of crisprcas-derived rna-guided endonucleases and nickases
-
doi: 10.1101/ gr.162339.113
-
Cho, S. W. et al. Analysis of off-Target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases. Genome Res. doi: 10.1101/ gr.162339.113 (2013
-
(2013)
Genome Res
-
-
Cho, S.W.1
|