Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors

Nucleic Acids Research

Volumn 42, Issue 7, 2014, Pages 4375-4390

  Hu, Jiabiao ^a   Lei, Yong ^a   Wong, Wing Ki ^a   Liu, Senquan ^a,b   Lee, Kai Chuen ^a   He, Xiangjun ^a   You, Wenxing ^a   Zhou, Rui ^a   Guo, Jun Tao ^c   Chen, Xiongfong ^d   Peng, Xianlu ^a,e   Sun, Hao ^a,e   Huang, He ^b   Zhao, Hui ^a   Feng, Bo ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b ZHEJIANG UNIVERSITY   (China)

^c University of North Carolina at Charlotte   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

^e CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE ACETYLTRANSFERASE PCAF; LUCIFERASE; OCTAMER TRANSCRIPTION FACTOR 4; RNA; SMALL GUIDE RNA; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CAS9; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; EMBRYO; EPIGENETICS; GENE EXPRESSION REGULATION; GENE REPRESSION; GENE SILENCING; GENE TARGETING; GENETIC ENGINEERING; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OCT4 GENE; PRIORITY JOURNAL; SOMATIC CELL; TRANSCRIPTION INITIATION SITE;

ANIMALS; CELLS, CULTURED; GENE SILENCING; HUMANS; MICE; OCTAMER TRANSCRIPTION FACTOR-3; P300-CBP TRANSCRIPTION FACTORS; RECOMBINANT FUSION PROTEINS; RNA, GUIDE; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION;

EID: 84898998655     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku109     Document Type: Article

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